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  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)

U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)

货号:CL-0236

规格:1×10⁶cells/T25培养瓶

价格: ¥1200

生长培养基:McCoy's 5A10% FBS1% P/S

数量: - +

  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
  • U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)

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U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确) ¥1200
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产品概述
产品信息
名称 U-2 OS [U2OS] (人骨肉瘤细胞) (STR鉴定正确)
别称 U-2 OS; U-2OS; U-2-OS; U2-OS; U20-S; U20S; 2T
种属
生长特性 贴壁细胞
细胞形态 上皮细胞样
冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
培养方案A(默认)
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
推荐传代比例 1:3-1:4
推荐换液频率 2-3次/周
参考资料(来源文献)
背景描述 U-2 OS细胞(原名2T)是由Ponten·J和Saksela·E在1964年从一名15岁女孩的胫骨中等分化的肉瘤中分离建立的。U-2 OS细胞与WI-38细胞共培养或用抗猴空泡病毒SV40、呼吸道合胞病毒RSV或腺病毒的补体结合试验(CF法)未检测到病毒。U-2 OS细胞表达胰岛素样生长因子I、II(IGF-I、IGF-II)受体和骨肉瘤衍生生长因子(ODGF)。
年龄(性别) 女性;15岁
组织来源 骨;骨肉瘤
细胞类型 肿瘤细胞
肿瘤类型 肉瘤细胞
生物安全等级 BSL-1
倍增时间 ~25-30 hours
受体表达情况 insulin-like growth factor I (IGF-I);insulin-like growth factor II (IGF II)
抗原表达情况 Blood Type A; Rh+; HLA A2, Aw30, B12, Bw35, B40(+/-)
基因表达情况 osteosacoma derived growth factor (ODGF), Blood Type A; Rh+; HLA A2, Aw30, B12, Bw35, B40(+/-)
保藏机构 ATCC; HTB-96 DSMZ; ACC-785 ECACC; 92022711
STR鉴定
  • STR位点信息
    Amelogenin X
    CSF1PO 13
    D2S1338 20,24
    D3S1358 16
    D5S818 11
    D7S820 11,12
    D8S1179 12,14
    D13S317 13
    D16S539 11,12
    D18S51 14
    D19S433 15
    D21S11 31
    FGA 20
    PentaD 9
    PentaE 10,13
    TH01 6,9.3
    TPOX 11,12
    vWA 14,18
    D6S1043 11
    D12S391 19,20
    D2S441 10,14
  • STR鉴定图
参考文献
文献列表
  • Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase(2021/08/05)

    作者:Ximing Shao, Zhihao Ding, Wenhua Zhou

    期刊:Nature Nanotechnology

    DOI:10.1038/s41565-021-00952-x

    影响因子 :38.300

    引用产品:CL-0016 CL-0101 CL-0103 CL-0236 CL-0238

  • Recruiting Rate Determines the Blinking Propensity of Rhodamine Fluorophores for Super-Resolution Imaging(2023/02/23)

    作者:Ying Zheng, Zhiwei Ye, Xue Zhang

    期刊:Journal of the American Chemical Society

    DOI:10.1021/jacs.2c11395

    影响因子 :15.000

    引用产品:CL-0236 CL-0242

  • Engineered biomimetic nanoreactor for synergistic photodynamic-chemotherapy against hypoxic tumor(2022/09/22)

    作者:Haoyu Guo, Lutong Wang, Wei Wu

    期刊:JOURNAL OF CONTROLLED RELEASE

    DOI:10.1016/j.jconrel.2022.09.020

    影响因子 :10.800

    引用产品:CL-0190 CL-0236 CL-0492 CP-H082

  • Bone-targeting exosome nanoparticles activate Keap1 / Nrf2 / GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells(2023/09/30)

    作者:Wenkai Chen, Zongguang Li, Naichun Yu

    期刊:JOURNAL OF NANOBIOTECHNOLOGY

    DOI:10.1186/s12951-023-02129-1

    影响因子 :10.200

    引用产品:CL-0157 CL-0202 CL-0236 CP-H166

  • Janus-Inspired Core–Shell Structure Hydrogel Programmatically Releases Melatonin for Reconstruction of Postoperative Bone Tumor(2023/01/05)

    作者:Wei Huang, Xiaoyue Wu, Yifan Zhao

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.2c18545

    影响因子 :9.500

    引用产品:CL-0029 CL-0157 CL-0236

  • Targeting visualization of malignant tumor based on the alteration of DWI signal generated by hTERT promoter–driven AQP1 overexpression(2022/01/19)

    作者:Liang Zhang, Mingfu Gong, Sheng Lei

    期刊:European Journal Of Nuclear Medicine And Molecular Imaging

    DOI:10.1007/s00259-022-05684-1

    影响因子 :9.100

    引用产品:CL-0016 CL-0103 CL-0236 CL-0313

  • lncRNA MELTF-AS1 facilitates osteosarcoma metastasis by modulating MMP14 expression(2021/08/26)

    作者:Lei Ding, Taiyuan Liu, Yuan Qu

    期刊:Molecular Therapy-Nucleic Acids

    DOI:10.1016/j.omtn.2021.08.022

    影响因子 :8.800

    引用产品:CL-0157 CL-0202 CL-0236 CL-0360

  • Subtle Structural Translation Magically Modulates the Super-Resolution Imaging of Self-Blinking Rhodamines(2023/02/14)

    作者:Ying Zheng, Zhiwei Ye, Yi Xiao

    期刊:Analytical Chemistry

    DOI:10.1021/acs.analchem.2c05298

    影响因子 :7.400

    引用产品:CL-0236 CL-0242

  • What role does GPR65 play in the progression of osteosarcoma? Its mechanism and clinical significance(2024/01/13)

    作者:Jin Qi, Sihang Liu, Zhirui Zhang

    期刊:Cancer Cell International

    DOI:10.1186/s12935-024-03216-5

    影响因子 :5.800

    引用产品:CL-0236

  • Roles of PTEN gene methylation in Se-CQDs induced mitochondrial apoptosis of osteosarcoma cells(2024/01/16)

    作者:Huahua Su, Yan Lv, Lixian Zhu

    期刊:COLLOIDS AND SURFACES B-BIOINTERFACES

    DOI:10.1016/j.colsurfb.2024.113757

    影响因子 :5.800

    引用产品:CL-0236

  • A1BG-AS1 promotes the biological functions of osteosarcoma cells via regulating the microRNA-148a-3p/USP22 axis and stabilizing the expression of SIRT1 through deubiquitinase function(2023/10/03)

    作者:Xiuxin Han, Mengfan Yin, Chen Gong

    期刊:EXPERT OPINION ON THERAPEUTIC TARGETS

    DOI:10.1080/14728222.2023.2263908

    影响因子 :5.800

    引用产品:CL-0236

  • 2-Hydroxy-3-methylanthraquinone inhibits homologous recombination repair in osteosarcoma through the MYC-CHK1-RAD51 axis(2023/01/30)

    作者:Doudou Jing, Xuanzuo Chen, Zhenhao Zhang

    期刊:MOLECULAR MEDICINE

    DOI:10.1186/s10020-023-00611-y

    影响因子 :5.700

    引用产品:CL-0236 CL-0492 CM-0236 CM-0492

  • Solasonine Inhibits Cancer Stemness and Metastasis by Modulating Glucose Metabolism via Wnt/β-Catenin/Snail Pathway in Osteosarcoma(2023/06/28)

    作者:Bangjun Wang, Yi Zhou, Peng Zhang

    期刊:AMERICAN JOURNAL OF CHINESE MEDICINE

    DOI:10.1142/S0192415X23500593

    影响因子 :5.700

    引用产品:CL-0236 CL-0360

  • Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway(2024/01/08)

    作者:Ziang Zheng, Xinghan Zhao, Bo Yuan

    期刊:MOLECULAR MEDICINE

    DOI:10.1186/s10020-024-00778-y

    影响因子 :5.700

    引用产品:CL-0236

  • RILP inhibits tumor progression in osteosarcoma via Grb10-mediated inhibition of the PI3K/AKT/mTOR pathway(2023/10/03)

    作者:Zhun Wei, Kezhou Xia, Di Zheng

    期刊:MOLECULAR MEDICINE

    DOI:10.1186/s10020-023-00722-6

    影响因子 :5.700

    引用产品:CL-0236

  • MicroRNA PC-3p-2869 Regulates Antler Growth and Inhibits Proliferation and Migration of Human Osteosarcoma and Chondrosarcoma Cells by Targeting CDK8, EEF1A1, and NTN1(2023/06/29)

    作者:Fan Yang, Jin Wu, Mindie Zhao

    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

    DOI:10.3390/ijms241310840

    影响因子 :5.600

    引用产品:CL-0005 CL-0157 CL-0236

  • m7G-related genes predict prognosis and affect the immune microenvironment and drug sensitivity in osteosarcoma(2023/08/16)

    作者:Zili Lin, Ziyi Wu, Yuhao Yuan

    期刊:Frontiers in Pharmacology

    DOI:10.3389/fphar.2023.1158775

    影响因子 :5.600

    引用产品:CL-0157 CL-0236

  • ATRX loss suppresses the type I interferon response in sarcoma cells through chromatin remodeling(2023/08/15)

    作者:Xinrui Wang, Zige Jin, Shanshan Tang

    期刊:American Journal of Cancer Research

    DOI:PMID:37693131

    影响因子 :5.300

    引用产品:CL-0005 CL-0157 CL-0202 CL-0236 CL-0360

  • Circular RNA hsa_circ_001350 contributes to osteosarcoma progression by regulating microRNA-578/CCR4-NOT transcription complex and subunit 7/Wnt signaling(2023/06/15)

    作者:Rujin Xu, Xingyuan Ci, Fang He

    期刊:American Journal of Cancer Research

    DOI:PMID:37424831

    影响因子 :5.300

    引用产品:CL-0157 CL-0202 CL-0236 CL-0360

  • Zinc finger Asp-His-His-Cys palmitoyl -acyltransferase 19 accelerates tumor progression through wnt/β-catenin pathway and is upregulated by miR-940 in osteosarcoma(2022/03/17)

    作者:Shuhong Liang, Xiaojian Zhang, Jun Li

    期刊:Bioengineered

    DOI:10.1080/21655979.2022.2040827

    影响因子 :4.900

    引用产品:CL-0157 CL-0236

  • Sulfatinib, a novel multi-targeted tyrosine kinase inhibitor of FGFR1, CSF1R, and VEGFR1–3, suppresses osteosarcoma proliferation and invasion via dual role in tumor cells and tumor microenvironment(2023/06/08)

    作者:Song Liao, Jianxiong Li, Song Gao

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2023.1158857

    影响因子 :4.700

    引用产品:CL-0157 CL-0190 CL-0236 CL-0360 CL-0371

  • Zyxin Inhibits the Proliferation, Migration, and Invasion of Osteosarcoma via Rap1-Mediated Inhibition of the MEK/ERK Signaling Pathway(2023/08/21)

    作者:Zhun Wei, Kezhou Xia, Bin Zhou

    期刊:Biomedicines

    DOI:10.3390/biomedicines11082314

    影响因子 :4.700

    引用产品:CL-0236

  • A ferroptosis-related gene signature associated with immune landscape and therapeutic response in osteosarcoma.(2022/11/11)

    作者:Xinxing Wang, Guang Xia, Shilang Xiao, Song Wu, Lina Zhang, Junjie Huang, Wenxiu Zhang, Xu Cao, Image_1.tif, Image_2.tif, Image_3.tif, Image_4.tif, Image_5.tif, Image_6.tif, Image_7.tif, DataSheet_1.csv, DataSheet_2.csv, DataSheet_3.csv, DataSheet_4.

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2022.1024915

    影响因子 :4.700

    引用产品:CL-0236 CL-0492 PM150411 PM150710

  • PNO1 promotes the progression of osteosarcoma via TGF-β and YAP/TAZ pathway(2023/12/09)

    作者:Long Fang, Baolong Wang, Zengkun Yang

    期刊:Scientific Reports

    DOI:10.1038/s41598-023-49295-8

    影响因子 :4.600

    引用产品:CL-0236

  • Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway(2023/03/05)

    作者:Xu Cai, Shaihong Zhu

    期刊:Genomics

    DOI:10.1016/j.ygeno.2023.110595

    影响因子 :4.400

    引用产品:CL-0157 CL-0236 CL-0492

  • RING finger gene 180 inhibits osteosarcoma progression through regulating chromobox homolog 4 ubiquitination(2023/04/24)

    作者:Qirui Zhao, Ning Liu, Tongtong Xu

    期刊:CELL CYCLE

    DOI:10.1080/15384101.2023.2205201

    影响因子 :4.300

    引用产品:CL-0005 CL-0157 CL-0202 CL-0236 CL-0492

  • Osteoblast-derived exosomes promote osteogenic differentiation of osteosarcoma cells via URG4/Wnt signaling pathway(2023/10/11)

    作者:Yuanxi Leng, Jingtang Li, Zhisheng Long

    期刊:BONE

    DOI:10.1016/j.bone.2023.116933

    影响因子 :4.100

    引用产品:CL-0236

  • Identification of an EMT-related gene-based prognostic signature in osteosarcoma(2023/04/27)

    作者:Haoli Gong, Ye Tao, Sheng Xiao

    期刊:Cancer Medicine

    DOI:10.1002/cam4.5942

    影响因子 :4.000

    引用产品:CL-0236 CL-0492 PM150411 PM150710

  • Down-regulation of PRR11 affects the proliferation, migration and invasion of osteosarcoma by inhibiting the Wnt/β-catenin pathway(2021/09/13)

    作者:Ke Li, Hongtao Yu, Chunbing Zhao

    期刊:Journal of Cancer

    DOI:10.7150/jca.62491

    影响因子 :3.900

    引用产品:CL-0157 CL-0202 CL-0236

  • A short peptide LINC00665_18aa encoded by lncRNA LINC00665 suppresses the proliferation and migration of osteosarcoma cells through the regulation of the CREB1/RPS6KA3 interaction(2023/06/07)

    作者:Junwei Pan, Ming Liu, Xiaozong Duan

    期刊:PLoS One

    DOI:10.1371/journal.pone.0286422

    影响因子 :3.700

    引用产品:164210 164210-50 CL-0236 CL-0492 PB180120 PM150210

  • Schisandrin B Inhibits Cell Viability and Migration, and Induces Cell Apoptosis by circ_0009112/miR-708-5p Axis Through PI3K/AKT Pathway in Osteosarcoma(2021/12/22)

    作者:Bing Wang, Xiaowei Wang, Xing Tong

    期刊:Frontiers in Genetics

    DOI:10.3389/fgene.2020.588670

    影响因子 :3.700

    引用产品:CL-0202 CL-0236

  • Disulfidptosis-related PABPC3 promotes tumor progression and inhibits immune activity in osteosarcoma(2023/12/07)

    作者:Yangbo Cao, Song Wu, Yishan Gu

    期刊:JOURNAL OF GENE MEDICINE

    DOI:10.1002/jgm.3641

    影响因子 :3.500

    引用产品:CL-0236

  • Diverse cell death patterns-related signature for predicting prognosis and drug sensitivity of osteosarcoma patients(2023/10/20)

    作者:Yanbin Shi, Song Wu, Xiaolin Zhang

    期刊:JOURNAL OF GENE MEDICINE

    DOI:10.1002/jgm.3613

    影响因子 :3.500

    引用产品:CL-0236

  • Circular RNA circDOCK1 contributes to osteosarcoma progression by acting as a ceRNA for miR-936 to regulate LEF1(2022/09/09)

    作者:Gang Xu, Haijiao Zhang, Yuxia Shi

    期刊:Journal of Bone Oncology

    DOI:10.1016/j.jbo.2022.100453

    影响因子 :3.400

    引用产品:CL-0236 CL-0360 CM-0236 CM-0360 CP-H082 PB180120

  • Hsa_circ_0000591 drives osteosarcoma glycolysis and progression by sequestering miR-194-5p and elevating HK2 expression(2023/02/21)

    作者:Dawei Wang, Yang Wang, Huadong Wang

    期刊:CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

    DOI:10.1111/1440-1681.13763

    影响因子 :2.900

    引用产品:CL-0157 CL-0236 CL-0360 PB180120

  • LPS combined with CD47mAb enhances the anti‑osteosarcoma ability of macrophages(2023/03/28)

    作者:Peng Yuan, Yukang Que, Yulei Liu

    期刊:Oncology Letters

    DOI:10.3892/ol.2023.13777

    影响因子 :2.900

    引用产品:CL-0157 CL-0190 CL-0236 CL-0371

  • PROSER2 is a poor prognostic biomarker for patients with osteosarcoma and promotes proliferation, migration and invasion of osteosarcoma cells(2022/11/08)

    作者:Zhengjiang Li, Yan Zhang, Yongkui Li, Shuxing Xing, Shunqiang Li, Jing Lyu, Zhaonan Ban

    期刊:Experimental and Therapeutic Medicine

    DOI:10.3892/etm.2022.11686

    影响因子 :2.700

    引用产品:CL-0157 CL-0236

  • DEPDC1 and KIF4A synergistically inhibit the malignant biological behavior of osteosarcoma cells through Hippo signaling pathway(2023/02/27)

    作者:Mingming Yang, Hang Zhang, Shichang Gao

    期刊:Journal of Orthopaedic Surgery and Research

    DOI:10.1186/s13018-023-03572-4

    影响因子 :2.600

    引用产品:CL-0157 CL-0202 CL-0236

  • Exosomal miR-331-3p derived from chemoresistant osteosarcoma cells induces chemoresistance through autophagy(2023/11/22)

    作者:Chenyang Meng, Yun Yang, Wei Feng

    期刊:Journal of Orthopaedic Surgery and Research

    DOI:10.1186/s13018-023-04338-8

    影响因子 :2.600

    引用产品:CL-0236

  • Piperine improves the sensitivity of osteosarcoma cells to doxorubicin by inducing apoptosis and inhibiting the PI3K/AKT/GSK-3β pathway(2023/03/09)

    作者:Yubin Qi, Lin Yao, Jianke Liu

    期刊:Journal of Orthopaedic Surgery and Research

    DOI:10.1186/s13018-023-03642-7

    影响因子 :2.600

    引用产品:CL-0236

  • Circ_0003732 promotes osteosarcoma progression through regulating miR-377-3p/CPEB1 axis and Wnt/β-catenin signaling pathway(2022/01/01)

    作者:Zheng Zhou, Tang Liu, Zhihong Li

    期刊:Anti-Cancer Drugs

    DOI:10.1097/CAD.0000000000001206

    影响因子 :2.389

    引用产品:CL-0236 CL-0360

  • circATP2A2 promotes osteosarcoma progression by upregulating MYH9(2021/11/22)

    作者:Xin Cao, Xianfeng Meng, Peng Fu

    期刊:Open Medicine

    DOI:10.1515/med-2021-0370

    影响因子 :2.100

    引用产品:CL-0202 CL-0236 CL-0360 PM150312

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