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  • MDA-MB-231 (人乳腺癌细胞) (L15) (STR鉴定正确)

MDA-MB-231 (人乳腺癌细胞) (L15) (STR鉴定正确)

货号:CL-0150A

规格:1×10⁶cells/T25培养瓶

价格: ¥1600

生长培养基:Leibovitz's L-1510% FBS1% P/S

数量: - +

  • MDA-MB-231 (人乳腺癌细胞) (L15) (STR鉴定正确)

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MDA-MB-231 (人乳腺癌细胞) (L15) (STR鉴定正确) ¥1600
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产品概述
产品信息
名称 MDA-MB-231 (人乳腺癌细胞) (L15) (STR鉴定正确)
别称 MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA231; MB231; MD Anderson-Metastatic Breast-231
种属
生长特性 贴壁细胞
细胞形态 上皮细胞样
生长培养基 Leibovitz's L-1510% FBS1% P/S
冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
培养条件 气相:空气,100% 温度:37℃
推荐传代比例 1:2-1:4
推荐换液频率 2~3次/周
注意事项 1、该细胞推荐使用Leibovitz's L-15培养基进行培养,Leibovitz's L-15不可以通入二氧化碳,会产生细胞毒性; 2、如您没有无二氧化碳的培养箱,可使用DMEM替代Leibovitz's L-15,使用DMEM培养基时即可正常通入5%二氧化碳; 3、配套专用培养基默认Leibovitz's L-15配置,如需DMEM配方,请联系销售下单备注更改。
参考资料(来源文献)
背景描述 MDA-MB-231来自患有转移乳腺腺癌的51岁女病人的胸水。 在裸鼠和ALS处理的BALB/c小鼠中,它能形成低分化腺癌(III级)。细胞表达WNT7B癌基因。
年龄(性别) 女性,51岁
组织来源 乳腺腺癌,转移性胸膜渗出液
细胞类型 肿瘤细胞
肿瘤类型 乳腺癌细胞
生物安全等级 1
倍增时间 ~32-42小时
致瘤性 Yes, in ALS treated BALB/c mice, forms poorly differentiated adenocarcinoma (grade III).Yes, in nude mice, forms poorly differentiated adenocarcinoma (grade III).
受体表达情况 epidermal growth factor (EGF), expressed;transforming growth factor alpha (TGF alpha), expressed
保藏机构 ATCC; CRL-12532ATCC; HTB-26 ATCC; CRM-HTB-26 BCRC; 60425 BCRJ; 0164 DSMZ; ACC-732 ECACC; 92020424
STR鉴定
  • STR位点信息
    Amelogenin X
    CSF1PO 12,13
    D2S1338 20,21
    D3S1358 16
    D5S818 12
    D7S820 8,9
    D8S1179 13
    D13S317 13
    D16S539 12
    D18S51 11,16
    D19S433 11,14
    D21S11 30,33.2
    FGA 22,23
    PentaD 11,14
    PentaE 11
    TH01 7,9.3
    TPOX 8,9
    vWA 15,18
    D6S1043 18
    D12S391 17,18
    D2S441 14,15
  • STR鉴定图
参考文献
文献列表
  • Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase(2021/08/05)

    作者:Ximing Shao, Zhihao Ding, Wenhua Zhou

    期刊:Nature Nanotechnology

    DOI:10.1038/s41565-021-00952-x

    影响因子 :38.300

    引用产品:CL-0016 CL-0101 CL-0103 CL-0150A CL-0150B CL-0236 CL-0238

  • A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer(2023/07/05)

    作者:Runjie Song, Peilan Guo, Xin Ren

    期刊:Molecular Cancer

    DOI:10.1186/s12943-023-01806-x

    影响因子 :37.300

    引用产品:CL-0005 CL-0114 CL-0149 CL-0150A CL-0228 CL-0247 CL-0290A CL-0525

  • Mitochondria-targeted magnetic gold nanoheterostructure for multi-modal imaging guided photothermal and photodynamic therapy of triple-negative breast cancer(2020/07/24)

    作者:Bo Li, Qian Zhou, Haiyang Wang

    期刊:Chemical Engineering Journal

    DOI:10.1016/j.cej.2020.126364

    影响因子 :15.100

    引用产品:CL-0150A CL-0150B

  • Zebrafish xenograft model for studying mechanism and treatment of non-small cell lung cancer brain metastasis(2021/11/20)

    作者:Ruoyue Fan, Jiaqi Wu, Yuyang Liu

    期刊:Journal Of Experimental & Clinical Cancer Research

    DOI:10.1186/s13046-021-02173-5

    影响因子 :11.300

    引用产品:CL-0149 CL-0150A

  • Up-regulated circBACH2 contributes to cell proliferation, invasion, and migration of triple-negative breast cancer(2021/4/19)

    作者:Xinxing Wang, Bingjian Xue, Yujie Zhang

    期刊:Cell Death & Disease

    DOI:10.1038/s41419-021-03684-x

    影响因子 :9.000

    引用产品:CL-0040 CL-0041 CL-0149 CL-0150A CL-0150B CL-0152A CL-0152B CL-0290A CL-0290B CL-0525

  • MCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis(2021/04/06)

    作者:Fengxia Chen, Qingqing Wang, Xiaoyan Yu

    期刊:Cell Death & Disease

    DOI:10.1038/s41419-021-03661-4

    影响因子 :9.000

    引用产品:CL-0005 CL-0041 CL-0114 CL-0150A CL-0150B CL-0380 CL-0525 PM150312B

  • Phenotype-related drug sensitivity analysis of single CTCs for medicine evaluation(2020/08/10)

    作者:Haimeng Pei, Mei Yu, Defang Dong

    期刊:Chemical Science

    DOI:10.1039/C9SC05566E

    影响因子 :8.400

    引用产品:CL-0149 CL-0150A CL-0150B

  • A Combined Self-Assembled Drug Delivery for Effective Anti-Breast Cancer Therapy(2021/03/23)

    作者:Hairong Wang, Yawen Zhang, Xiangle Zeng

    期刊:International Journal of Nanomedicine

    DOI:10.2147/IJN.S299681

    影响因子 :8.000

    引用产品:CL-0149 CL-0150A CL-0150B

  • Therapeutic Effect of Doxorubicin-Chlorin E6-Loaded Mesoporous Silica Nanoparticles Combined with Ultrasound on Triple-Negative Breast Cancer(2020/04/21)

    作者:Peng Xu, Jia Yao, Zhen Li

    期刊:International Journal of Nanomedicine

    DOI:10.2147/IJN.S243037

    影响因子 :8.000

    引用产品:CL-0150A CL-0150B

  • Oxypalmatin regulates proliferation and apoptosis of breast cancer cells by inhibiting PI3K/AKT signaling and its efficacy against breast cancer organoids(2023/03/10)

    作者:Xian Lin, Dong Chen, Xinyu Chu

    期刊:PHYTOMEDICINE

    DOI:10.1016/j.phymed.2023.154752

    影响因子 :7.900

    引用产品:CL-0093 CL-0149 CL-0150A CL-0719

  • A self-assembled RNA-triple helix hydrogel drug delivery system targeting triple-negative breast cancer(2019/11/08)

    作者:Lairong Ding, Junwei Li, Changrong Wu

    期刊:Journal of Materials Chemistry B

    DOI:10.1039/C9TB01610D

    影响因子 :7.571

    引用产品:CL-0150A CL-0150B

  • Simultaneous Fluorescence Visualization of Epithelial-Mesenchymal Transition and Apoptosis Processes in Tumor Cells for Evaluating the Impact of Epithelial-Mesenchymal Transition on Drug Efficacy(2018/09/18)

    作者:Mingming Luan, Jinjie Chang, Wei Pan

    期刊:Analytical Chemistry

    DOI:10.1021/acs.analchem.8b02494

    影响因子 :7.400

    引用产品:CL-0150A CL-0150B CL-0184 CL-0525

  • Assessment of 2-allyl-4,5-dimethoxyphenol safety and attractiveness to mature males of Bactrocera dorsalis (Hendel)(2021/08/04)

    作者:Shuzhen Deng, Xinyang Li, Ziming Wang

    期刊:Ecotoxicology And Environmental Safety

    DOI:10.1016/j.ecoenv.2021.112567

    影响因子 :6.800

    引用产品:CL-0037 CL-0106 CL-0150A CL-0150B

  • Small nucleolar RNA SNORA71A promotes epithelial-mesenchymal transition by maintaining ROCK2 mRNA stability in breast cancer(2022/03/30)

    作者:Ting Hu, Chong Lu, Yun Xia

    期刊:Molecular Oncology

    DOI:10.1002/1878-0261.13186

    影响因子 :6.600

    引用产品:CL-0149 CL-0150A

  • UBE2C affects breast cancer proliferation through the AKT/mTOR signaling pathway(2021/10/20)

    作者:Zinan Lu, Jia Song, Tonghui Sun

    期刊:Chinese Medical Journal

    DOI:10.1097/CM9.0000000000001708

    影响因子 :6.100

    引用产品:CL-0149 CL-0150A

  • CXCL9 influences the tumor immune microenvironment by stimulating JAK/STAT pathway in triple-negative breast cancer(2022/12/06)

    作者:Lei Wu, Shengnan Sun, Fei Qu

    期刊:CANCER IMMUNOLOGY IMMUNOTHERAPY

    DOI:10.1007/s00262-022-03343-w

    影响因子 :5.800

    引用产品:CL-0150A

  • Ribociclib (LEE011) suppresses cell proliferation and induces apoptosis of MDA-MB-231 by inhibiting CDK4/6-cyclin D-Rb-E2F pathway(2019/10/07)

    作者:Tianqi Li, Yudi Xiong, Qingqing Wang

    期刊:Artificial Cells Nanomedicine and Biotechnology

    DOI:10.1080/21691401.2019.1670670

    影响因子 :5.800

    引用产品:CL-0150A CL-0150B CL-0525

  • Co-delivery of epirubicin and paclitaxel using an estrone-targeted PEGylated liposomal nanoparticle for breast cancer(2020/01/05)

    作者:Huan Tang, Jinglin Chen, Lin Wang

    期刊:International Journal of Pharmaceutics

    DOI:10.1016/j.ijpharm.2019.118806

    影响因子 :5.800

    引用产品:CL-0150A CL-0150B

  • CircFBXL5 promotes the 5-FU resistance of breast cancer via modulating miR-216b/HMGA2 axis(2021/07/19)

    作者:Mingzhi Zhu, Yanyan Wang, Fang Wang

    期刊:Cancer Cell International

    DOI:10.1186/s12935-021-02088-3

    影响因子 :5.800

    引用产品:CL-0150A CL-0150B CL-0152A CL-0152B CL-0525

  • Dysfunction of the ST7-AS1/miR-301b-3p/BTG1 ceRNA network promotes immune escape of triple-negative breast cancer(2023/02/14)

    作者:Yong Li, Wenge Xin, Fang Liu

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2023.109805

    影响因子 :5.600

    引用产品:CL-0007 CL-0150A

  • Weighted gene correlation network analysis identifies RSAD2, HERC5, and CCL8 as prognostic candidates for breast cancer(2019/06/21)

    作者:Jianing Tang, Qian Yang, Qiuxia Cui

    期刊:Journal Of Cellular Physiology

    DOI:10.1002/jcp.28980

    影响因子 :5.600

    引用产品:CL-0150A CL-0150B

  • Circular RNA circ-ERBB2 Elevates the Warburg Effect and Facilitates Triple-Negative Breast Cancer Growth by the MicroRNA 136-5p/Pyruvate Dehydrogenase Kinase 4 Axis | Molecular and Cellular Biology(2021/9/24)

    作者:Yihong Huang, Shuo Zheng, Ying Lin, Liming Kea

    期刊:Molecular And Cellular Biology

    DOI:10.1128/MCB.00609-20

    影响因子 :5.300

    引用产品:164210 CL-0041 CL-0150A CL-0152A CL-0290A CL-0525 PB180120 PM150110 PM151010

  • The curcumin analog EF24 inhibits proliferation and invasion of triple-negative breast cancer cells by targeting the lncRNA HCG11/Sp1 axis | Molecular and Cellular Biology(2021/11/15)

    作者:Yin Duan, Huiling Chen, Min Ling

    期刊:Molecular And Cellular Biology

    DOI:10.1128/MCB.00163-21

    影响因子 :5.300

    引用产品:CL-0041 CL-0150A CL-0290A

  • Enzymatic rhamnosylation of anticancer drugs by an α-l-rhamnosidase from Alternaria sp. L1 for cancer-targeting and enzyme-activated prodrug therapy(2019/08/08)

    作者:Li Xu , Xiaohong Liu , Yinping Li

    期刊:Applied Microbiology And Biotechnology

    DOI:10.1007/s00253-019-10011-0

    影响因子 :5.000

    引用产品:CL-0150A CL-0150B CL-0525

  • Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin(2021/6/2)

    作者:Yan Wang, Zhiqiang Cheng, Jing Xu

    期刊:Bioengineered

    DOI:10.1080/21655979.2021.1924544

    影响因子 :4.900

    引用产品:CL-0114 CL-0149 CL-0150A PM151010

  • Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6(2020/06/11)

    作者:Meng Jin, Daili Gao, Rongchun Wang

    期刊:Oncology Reports

    DOI:10.3892/or.2020.7644

    影响因子 :4.200

    引用产品:CL-0149 CL-0150A CL-0150B

  • Mesothelin-targeted CAR-NK Cells Derived From Induced Pluripotent Stem Cells Have a High Efficacy in Killing Triple-negative Breast Cancer Cells as Shown in Several Preclinical Models(2023/08/15)

    作者:Mei Yang, Tian Guan, Chunfa Chen

    期刊:JOURNAL OF IMMUNOTHERAPY

    DOI:10.1097/CJI.0000000000000483

    影响因子 :3.900

    引用产品:CL-0150A

  • Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell(2019/08/14)

    作者:Mingjiang Yao, Xiaodi Fan, Bo Yuan

    期刊:BMC Complementary and Alternative Medicine volume

    DOI:10.1186/s12906-019-2615-4

    影响因子 :3.900

    引用产品:CL-0150A CL-0150B

  • Ferroptosis regulators, especially SQLE, play an important role in prognosis, progression and immune environment of breast cancer(2021/10/29)

    作者:Wenqing Tang, Fangshi Xu, Meng Zhao

    期刊:Bmc Cancer

    DOI:10.1186/s12885-021-08892-4

    影响因子 :3.800

    引用产品:CL-0149 CL-0150A CL-0150B CL-0525

  • CKAP2L, transcriptionally inhibited by FOXP3, promotes breast carcinogenesis through the AKT/mTOR pathway(2022/01/21)

    作者:Feng Chi, Long Chen, Xiaoming Jin

    期刊:EXPERIMENTAL CELL RESEARCH

    DOI:10.1016/j.yexcr.2022.113035

    影响因子 :3.700

    引用产品:CL-0150A CL-0211 CL-0228 CL-0290A PM150710 PM151010

  • Circular RNA circHMCU promotes breast tumorigenesis through miR-4458/PGK1 regulatory cascade(2023/03/23)

    作者:Shubian Qiu, Lele Zou, Ruimin Qiu

    期刊:HEREDITAS

    DOI:10.1186/s41065-023-00275-y

    影响因子 :2.700

    引用产品:CL-0005 CL-0149 CL-0150A CL-0525 PM150210 PM150312 PM150411 PM151010

  • The Antitumor Potential of Extract of the Oak Bracket Medicinal Mushroom Inonotus baumii in SMMC-7721 Tumor Cells(2019/09/22)

    作者:Yue Yang, Pingya He

    期刊:Evidence-Based Complementary and Alternative Medicine

    DOI:10.1155/2019/1242784

    影响因子 :2.650

    引用产品:CL-0150A CL-0150B CL-0215

  • Hsa_circ_0069094 positively regulates the expression of oncogenic ZNF217 by competitively targeting miR-758–3p to promote the development of breast cancer(2022/11/08)

    作者:Huaqing Ou, Jialing Li, Qinhua Lv, Decai Feng

    期刊:Reproductive Biology

    DOI:10.1016/j.repbio.2022.100708

    影响因子 :2.100

    引用产品:CL-0041 CL-0150A CL-0525 PM150110 PM150210 PM151010

  • Lidocaine prevents breast cancer growth by targeting neuronatin to inhibit nerve fibers formation(2021/7/1)

    作者:Bingda Li, Hao Xu, Chongwu He

    期刊:Journal Of Toxicological Sciences

    DOI:10.2131/jts.46.329

    影响因子 :2.000

    引用产品:CL-0007 CL-0150A

  • DNAJB4 identified as a potential breast cancer marker: evidence from bioinformatics analysis and basic experiments(2020/12/1)

    作者:Linlong Mo, Jiayou Liu, Ziquan Yang

    期刊:Gland Surgery

    DOI:10.21037/gs-20-431

    影响因子 :1.800

    引用产品:CL-0150A CL-0383A CL-0525

  • CircRNA DNA methyltransferase 1 silence inhibits breast cancer development by regulating micoRNA-485-3p/zinc finger E-box binding homeobox 1 axis(2021/01/05)

    作者:Chen Xie, Junyu Li, Chen Xu

    期刊:Journal Of Obstetrics And Gynaecology Research

    DOI:10.1111/jog.14639

    影响因子 :1.600

    引用产品:CL-0149 CL-0150A CL-0525

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