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产品概述
名称 | Neuro-2a [N2a; Neuro-2a] (小鼠脑神经瘤细胞) (种属鉴定正确) |
别称 | NEURO-2A; Neuro 2a; Neuro2a; Neuro2A; N-2a; N2a; N2A; Nb2a; NB2a |
种属 | 小鼠 |
生长特性 | 贴壁细胞 |
细胞形态 | 神经细胞样、阿米巴样 |
生长培养基 | MEM(含NEAA)+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | Neuro-2a [N2a; Neuro-2a]细胞是由R·J·Klebe和F·H·Ruddle经A株白鼠的自生肿瘤建立;Neuro-2a [N2a; Neuro-2a]细胞产生大量微管蛋白,此蛋白在神经细胞中起应答轴浆流动的收缩系统作用。 |
组织来源 | 脑神经母细胞瘤,神经母细胞 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 神经母细胞瘤细胞 |
生物安全等级 | 1 |
倍增时间 | ~70 hours |
抗原表达情况 | H-2, a haploType; Mus musculus, expressed |
基因表达情况 | acetylcholinesterase, tubulin |
保藏机构 | ATCC; CCL-131 DSMZ; ACC-148 ECACC; 89121404 |
STR鉴定
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STR位点信息
18-3 22 6-7 12 5-5 15,17 X-1 26,27 1-2 17,18 7-1 25.2 8-1 16,17 1-1 11 19-2 12 15-3 21.3,22.3,23.3,24.3 12-1 16 6-4 18,20 4-2 21.3,22.3 3-2 13,14 2-1 16 13-1 16.2,17.2
11-2 15 17-2 16 -
STR鉴定图
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参考文献
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CircSV2b participates in oxidative stress regulation through miR-5107-5p-Foxk1-Akt1 axis in Parkinsons disease(2022/08/12)
作者:Quancheng Cheng, Jianwei Wang, Man Li
期刊:Redox Biology
DOI:10.1016/j.redox.2022.102430
影响因子 :10.7870
引用产品:CL-0168
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Olfactory bulb microglia activation mediated neuronal death in real-ambient particulate matter exposure mice with depression-like behaviors(2022/01/29)
作者:Xiaoya Ji, Rui Liu, Jiajun Guo
期刊:Science Of The Total Environment
DOI:10.1016/j.scitotenv.2022.153456
影响因子 :10.7530
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Piceatannol-3′-O-β-D-glucopyranoside attenuates colistin-induced neurotoxicity by suppressing oxidative stress via the NRF2/HO-1 pathway(2023/02/21)
作者:Liguang Xiong, Debiao Xiang, Fang Yuan
期刊:BIOMEDICINE & PHARMACOTHERAPY
DOI:10.1016/j.biopha.2023.114419
影响因子 :7.4190
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Dietary High-Fat Promotes Cognitive Impairment by Suppressing Mitophagy(2023/01/21)
作者:Jie Wen, Yangyang Wang, Chuanling Wang
期刊:Oxidative Medicine and Cellular Longevity
影响因子 :7.3100
引用产品:CL-0168
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Downregulation of BACH1 Protects AGAINST Cerebral Ischemia/Reperfusion Injury through the Functions of HO-1 and NQO1(2020/6/1)
作者:Shan Yu, Jingjie Zhai, Jing Yu
期刊:Neuroscience.
DOI:10.1016/j.neuroscience.2020.04.014.
影响因子 :3.7080
引用产品:CL-0168
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Activation of β2-adrenergic receptor ameliorates amyloid-β-induced mitophagy defects and tau pathology in mice(2022/10/05)
作者:Gaoshang Chai, Jiajun Wu, Juan Gong
期刊:NEUROSCIENCE
DOI:10.1016/j.neuroscience.2022.09.020
影响因子 :3.7080
引用产品:CL-0168
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Neuroprotective effects of miR-532-5p against ischemic stroke(2020/01/21)
作者:Jingwei Mu, Xi Cheng, Shanshan Zhong
期刊:Metabolic Brain Disease
DOI:10.1007/s11011-020-00544-z
影响因子 :3.655
引用产品:CL-0168
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LncRNA SNHG3 promotes autophagy-induced neuronal cell apoptosis by acting as a ceRNA for miR-485 to up-regulate ATG7 expression( 2020/8/29)
作者:Yanbin Cao, Lihua Pan, Xuejun Zhang
期刊:Metabolic Brain Disease
DOI:10.1007/s11011-020-00607-1
影响因子 :3.5840
引用产品:CL-0168
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miR‑183‑5p attenuates cerebral ischemia injury by negatively regulating PTEN(2020/9/7)
作者:Li Zhu, Xueying Zhou, Shanshan Li
期刊:Molecular Medicine Reports
影响因子 :3.4230
引用产品:CL-0168
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Molecular mechanism of Acanthopanax senticosus in the treatment of Alzheimer’s disease based on network pharmacology and molecular docking(2022/12/28)
作者:Kuang Feng, Xiang Tao
期刊:MOLECULAR DIVERSITY
DOI:10.1007/s11030-022-10586-3
影响因子 :3.3640
引用产品:CL-0168