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| 名称 | RAW 264.7 (小鼠单核巨噬细胞白血病细胞) (种属鉴定正确) |
| 别称 | RAW264; RAW2647; RAW264.7; RAW-264.7; Raw 264.7; Raw264.7 |
| 种属 | 小鼠 |
| 年龄（性别） | 雄；成年 |
| 组织来源 | Abelson鼠科白血病病毒诱导的肿瘤；单核细胞；巨噬细胞 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 不规则形 |
| 背景描述 | RAW 264.7细胞源自Abelson鼠科白血病病毒诱导的肿瘤；sIg-、Ia-抗原、Thy-1.2表面抗原阴性。RAW 264.7细胞不分泌可检测到的病毒颗粒，XC斑点形成试验阴性。RAW 264.7细胞可以胞饮中性红并吞噬乳胶颗粒与酵母聚糖，并且可以抗体依赖性地分解绵羊红血球与肿瘤靶细胞。LPS或PPD处理2天可诱导RAW 264.7细胞分解红血球，但对肿瘤靶细胞无作用。 |
| 生物安全等级 | 2 |
| 生长培养基 | DMEM(PM150210)＋10% FBS(164210-500)＋1% P/S(PB180120) |
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 倍增时间 | ~12-30 hours |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 受体表达情况 | complement (C3) |
| 抗原表达情况 | H-2d |
| 基因表达情况 | lysozyme, H-2d; Tested and found negative for ectromelia virus (mousepox). |
| 保藏机构 | ATCC; TIB-71 ECACC; 91062702 |
STR鉴定
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STR位点信息
18-3 18 9-2 14.3 6-7 12 5-5 14 X-1 24 15-3 22.3 12-1 16 6-4 18 4-2 22.3 jaridl Y,X -
STR鉴定图
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参考文献
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Evaluation of efficacy on RANKL induced osteoclast from RAW264.7 cells(2018.12.04)
作者：Chengchao Song, Xiaobin Yang, Yongsheng Lei, Zhen Zhang, Wanli Smith, Jinglong Yan
期刊：journal of cellular physiology
影响因子 ：5.546
引用产品：CL-0190
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Cellular study of the LPS‐induced osteoclastic multinucleated cell formation from RAW264.7 cells(2019.06.21)
作者：Yuan Xiao, Yang Cao, Chengchao Song
期刊：Journal of Cellular Physiology
影响因子 ：5.546
引用产品：CL-0190
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Activation of RAW264.7 macrophages by an acidic polysaccharide derived from Citrus grandis ‘Tomentosa’(2020.08.01)
作者：Ruiyi Fan, Congyi Zhu, Diyang Qiu
期刊：International Journal of Biological Macromolecules
DOI：10.1016/j.ijbiomac.2019.11.172
影响因子 ：5.162
引用产品：CL-0190
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Dual-functional lipid polymeric hybrid pH-responsive nanoparticles decorated with cell penetrating peptide and folate for therapy against rheumatoid arthritis(19 June 2018)
作者：Jinlong Zhaoa, Xueyan Zhanga, Xiangshi Sun
期刊：European Journal of Pharmaceutics and Biopharmaceutics
DOI：10.1016/j.ejpb.2018.06.020
影响因子 ：4.604
引用产品：CL-0190
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Study of double-targeting nanoparticles loaded with MCL-1 siRNA and dexamethasone for adjuvant-induced arthritis therapy(September 2020)
作者：Xiangyu Li, Changhui Yu, Xiangxue Meng
期刊：European Journal of Pharmaceutics and Biopharmaceutics
DOI：10.1016/j.ejpb.2020.07.009
影响因子 ：4.604
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Dual-functional lipid polymeric hybrid pH-responsive nanoparticles decorated with cell penetrating peptide and folate for therapy against rheumatoid arthritis(2018.09)
作者：Jinlong Zhao, Xueyan Zhang, Xiangshi Sun
期刊：European Journal of Pharmaceutics and Biopharmaceutics
DOI：10.1016/j.ejpb.2018.06.020
影响因子 ：4.604
引用产品：CL-0190
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Three new monoterpene glycosides from oil peony seed cake(2018.01)
作者：PuLiuYu Zhang, Yi-Fan Xu, Xin-Yue Zhu
期刊：Industrial Crops and Products
DOI：10.1016/j.indcrop.2017.10.043
影响因子 ：4.244
引用产品：CL-0190
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Tantalum boride as a biocompatible coating to improve osteogenesis of the bionano interface(2020.03.29)
作者：Ruiyan Li, Guancong Liu, Lina Yang, Yun'an Qing
期刊：J Biomed Mater Res A
影响因子 ：3.525
引用产品：CL-0190
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Artemisinin alleviates atherosclerotic lesion by reducing macrophage inflammation via regulation of AMPK/NF-κB/NLRP3 inflammasomes pathway(2019.07.16)
作者：Yan Jiang
期刊：Journal of Drug Targeting
DOI：10.1080/1061186X.2019.1616296
影响因子 ：3.38
引用产品：CL-0190
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Curcumin prevents osteocyte apoptosis by inhibiting M1‐type macrophage polarization in mice model of glucocorticoid‐associated osteonecrosis of the femoral head(2020.02.03)
作者：Shengyang Jin, Chunqing Meng, Yu He
期刊：Journal of Orthopaedic Research
影响因子 ：2.728
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Electrochemical sensing of H2O2 released from living cells based on AuPd alloy-modified PDA nanotubes(2019.02.20)
作者：Guangli He, Fengli Gao, Wei Li, Pengwei Li
期刊：Analytical Methods
影响因子 ：2.596
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Placenta‑derived mesenchymal stem cells ameliorate lipopolysaccharide‑induced inflammation in RAW264.7 cells and acute lung injury in rats(2020.06.15)
作者：Wen Yuan Heng‑Ya Song Jie Xiong
期刊：Molecular Medicine Reports
影响因子 ：2.1
引用产品：CL-0190
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Artemargyinolide E, a new sesquiterpene lactone from Artemisia argyi inhibits inflammatory responses via down-regulating NF-κB signaling pathway(2020.04)
作者：Lai-Bin Zhang, Hui-Hui Zhu
期刊：Phytochemistry Letters
DOI：10.1016/j.phytol.2020.01.009
影响因子 ：1.459
引用产品：CL-0190
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Anti-inflammatory activities of gentiopicroside against iNOS and COX-2 targets(2019.01)
作者：Qi-li Zhang, Jian Zhang, Peng-fei Xia
期刊：Chinese Herbal Medicines
DOI：10.1016/j.chmed.2018.10.004
影响因子 ：0
引用产品：CL-0190
