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产品概述
| 名称 | SMMC-7721 (人肝癌细胞)(暂不出售） |
| 别称 | SMMC 7721; SMMC7721; H7721; H-7721 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 生长培养基 | RPMI-1640＋10% FBS＋1% P/S |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 背景描述 | SMMC-7721细胞取自人肝癌组织，采用静置和旋转管法培养11天细胞开始生长，首次传代23天。SMMC-7721细胞AFP阳性；用Northern Blot方法，未能检测到SMMC-7721细胞中1.3kb LFIRE-1/HFREP-1 mRNA的表达，免疫缺陷小鼠体内可成瘤。(STR检测位点同HELA) |
| 年龄（性别） | 男 |
| 组织来源 | 肝癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肝胆癌细胞 |
参考文献
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MiR-342-3p inhibits LCSC oncogenicity and cell stemness through HDAC7/PTEN axis(2021/11/29)
作者：Chunlin Xu, Weiwei Sun, Jinglei Liu
期刊：Inflammation Research
DOI：10.1007/s00011-021-01521-7
影响因子 ：6.700
引用产品：CL-0216
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A confined crosslinking strategy towards an intelligent organosilica–micellar hybrid drug delivery system(2022/1/18)
作者：Xing Qin, Limei Qin, Jianping He
期刊：Biomaterials Science
影响因子 ：6.600
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A metabolic data-driven systems pharmacology strategy for decoding and validating the mechanism of Compound Kushen Injection against HCC(2021/3/20)
作者：Kexin Wang, Yupeng Chen, Aiping Lu
期刊：Journal Of Ethnopharmacology
影响因子 ：5.400
引用产品：CL-0216
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Study on the anti-hepatocarcinoma effect and molecular mechanism of Prunella vulgaris total flavonoids(2021/3/4)
作者：Yagang Song, Le Kang, Shuo Tian
期刊：Journal Of Ethnopharmacology
影响因子 ：5.400
引用产品：CL-0216
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Overexpression of YEATS2 Remodels the Extracellular Matrix to Promote Hepatocellular Carcinoma Progression via the PI3K/AKT Pathway(2023/03/20)
作者：Xin Liu, Yi Hu, Cairong Li, Jiayu Chen
期刊：Cancers
影响因子 ：5.200
引用产品：CL-0216
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KDM1A Promotes Immunosuppression in Hepatocellular Carcinoma by Regulating PD-L1 through Demethylating MEF2D(2021/07/02)
作者：Yonglan Wang, Kun Cao
期刊：Journal of Immunology Research
影响因子 ：4.493
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LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma(2020/05/21)
作者：Wei Zhang, Lei Han, Peng Xing
期刊：Naunyn-Schmiedebergs Archives of Pharmacology
DOI：10.1007/s00210-020-01889-z
影响因子 ：3.600
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LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma(2020/05/21)
作者：Wei Zhang, Lei Han, Peng Xing
期刊：Naunyn-Schmiedebergs Archives of Pharmacology
DOI：10.1007/s00210-020-01889-z
影响因子 ：3.600
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miR-381 Reverses Multidrug Resistance by Negative Regulation of the CTNNB1/ABCB1 Pathway in HepG2/Dox Cells, and the Diagnostic and Prognostic Values of CTNNB1/ABCB1 Are Identified in Patients with LIHC(2021/12/16)
作者：Bangming Pu, Xiaolan Yu, Yong Cao
期刊：Dna And Cell Biology
影响因子 ：3.100
引用产品：CL-0216
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ATP6V1F is a novel prognostic biomarker and potential immunotherapy target for hepatocellular carcinoma(2023/08/16)
作者：Xinyao Hu, Dan Li, Hua Zhu
期刊：BMC Medical Genomics
DOI：10.1186/s12920-023-01624-6
影响因子 ：2.700
