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产品概述
适用细胞：
干细胞，内皮细胞，上皮细胞， 神经细胞，软骨细胞， 肌细胞， 成纤维细胞， 其他原代细胞以及所有的细胞系。
产品特性：
① 低内毒素，无细菌、支原体、噬菌体、病毒等污染；
② 无外源添加因子，不含激素、抗生素等；
③ 已通过本公司肿瘤细胞库中500种细胞系、400多种原代细胞的验证，细胞增殖速度快，状态良好，可放心使用。
注意事项：
1、产品验收：
① 血清内外包装均应完好，无破损、裂缝、溢渗等现象；
② 血清到货时应为冷冻或冰水混合状态，不应完全融化；
③ 若出现上述现象，请拍照取证后及时与我们联系，以便及时进行更换。
2、血清的解冻：
① 请在2℃～8℃环境中解冻，不宜在较高温度下进行解冻；解冻温度较高会导致血清浑浊，沉淀增加，品质下降；
② 血清解冻的过程中请不时摇匀（小心勿造成气泡），使血清成分和温度均匀，从而减少沉淀的产生；
③ 血清解冻后应尽快用完，尽量避免反复冻融；
④ 血清不宜在室温中长时间放置，使用后尽快放回2℃～8℃中；
⑤ 高温解冻、剧烈摇晃、反复冻融、放置时间过长等，均会导致血清品质的降低。
3、运输及储存条件
运输条件：冷冻、密封、避光；
储存条件：贮藏温度≤-15℃， 可长时间保存； 4℃存放时，请勿超过一个月。
FAQs:
Q1：如何解冻血清才不会使产品质量受损？
A1：① 将血清从低温冰箱取出后，先于2-8℃冰箱放置12-24小时左右使之部分溶解，然后在室温下使之全溶；但必须注意的是，溶解过程中必须规则地摇晃均匀。
② 切勿将刚刚从-20℃冰箱里拿出来的血清直接放在水浴中，无论室温的水或者37℃的水；因为在水浴中血清迅速融化，过大的温差变化（-20℃→37℃，温差为57℃）极其容易造成血清析出沉淀。
③ 血清应该置于-15℃以下保存；若一次无法用完一瓶，应该无菌分装，再冷冻保存，避免反复冻融。
Q2：血清中可能出现的沉淀物是什么？
A2：① 纤维蛋白，它是经常出现的较大的沉淀物，可以达到1-2mm，可以用肉眼观察到。
② 磷酸钙，它也是常见的一种沉淀物，通常会使血清出现浑浊，并且在37℃培养的时候会增加。这种沉淀物在倒置显微镜下观察像小黑点，这些小黑点由于布朗运动看上去可以活动，因此经常被误认为是微生物污染。
③ 胆固醇、脂肪酸酯以及一些蛋白质，它们也是血清中出现沉淀物的常见原因。关于细胞生长，我们的试验以及经验表明沉淀物不会影响细胞培养，我们的客户以及其它血清生产商也证明了这一点。
Q3：血清解冻后发现有絮状沉淀物出现，该如何处理？
A3：若您欲去除这些絮状沉淀物，可以将血清分装至无菌离心管内，以400-600g离心5min，上清液即可加入培养基内一起培养。 我们不建议您以过滤的方法去除这些絮状沉淀物，一方面它可能会阻塞您的过滤膜；另一方面，过滤血清这种行为可能会导致血清中部分营养成分的流失。
Q4：如何避免沉淀物的产生？
A4：温度过高、时间过久、摇晃不均匀等，都会造成沉淀增多；我们建议，如非必要，无须对血清进行灭活；若必须热灭活，应严格遵守56℃、30min 的原则，并随时摇晃均匀。
Q5：保存血清最好的方法是什么？
A5：需长期保存的血清必须储存于-15℃或更低温冰箱中；研究表明，储存在-80℃下的血清在性能方面没有任何变化，但解冻时巨大的温差会导致更多沉淀的产生，故不建议-80℃储存。血清在4℃冰箱存放时间切勿超过1个月；若一次无法用完1瓶，建议分装后保存，避免反复冻融。另外，血清结冰体积会增加约10%，分装时请预留一定的体积空间。
关于我们的血清产品，如您有任何疑问或要求，请点击右侧在线咨询联系我们，或点击右下方的在线留言按钮给我们留言，我们专业的技术人员会第一时间答复您。
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Comprehensive characterization of extracellular matrix-related genes in PAAD identified a novel prognostic panel related to clinical outcomes and immune microenvironment: A silico analysis with in vivo and vitro validation(2022/10/13)
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CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1(2022/11/12)
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Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction(2022/08/31)
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The Involvement of Macrophage Colony Stimulating Factor on Protein Hydrolysate Injection Mediated Hematopoietic Function Improvement(2021/10/16)
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引用产品：164210 164210-50 CL-0005 CL-0016 CL-0165 CL-0166 CL-0249 CL-0299 PB180120 PM150110
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Advanced Oxidation Protein Product Promotes Oxidative Accentuation in Renal Epithelial Cells via the Soluble (Pro)renin Receptor-Mediated Intrarenal Renin-Angiotensin System and Nox4-H2O2 Signaling(2021/11/26)
作者：Kai Xue,Yurong Wang,Yan Wang
期刊：Oxidative Medicine and Cellular Longevity
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Mesangial Cell–Derived Exosomal miR-4455 Induces Podocyte Injury in IgA Nephropathy by Targeting ULK2(2022/11/04)
作者：Mengjie Yu, Xiaogang Shen, Wenfang He, Danna Zheng, Qiang He, Juan Jin
期刊：Oxidative Medicine and Cellular Longevity
影响因子 ：7.3100
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PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib(2022/09/05)
作者：Xiaocui Zhang, Meige Sun, Yisheng Jiao
期刊：Oxidative Medicine and Cellular Longevity
影响因子 ：7.3100
引用产品：164210 164210-50 CL-0013 CL-0079 CL-0178 P-CA-161 PM150110 PM150710
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Design, synthesis, and evaluation of amphiphilic sofalcone derivatives as potent Gram-positive antibacterial agents(2020/07/08)
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期刊：European Journal of Medicinal Chemistry
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Glyconanoparticles with Activatable Near-Infrared Probes for Tumor-Cell Imaging and Targeted Drug Delivery(2022/04/02)
作者：Guanyu Chi, Yinghua Lv, Shuang Chao
期刊：International Journal of Nanomedicine
影响因子 ：7.0330
引用产品：164210
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Multifunctional folate receptor-targeting and pH-responsive nanocarriers loaded with methotrexate for treatment of rheumatoid arthritis(2017/09/11)
作者：Jinlong Zhao, Menghui Zhao, Changhui Yu
期刊：International Journal of Nanomedicine
影响因子 ：7.0330
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Facile synthesis of yellowish-green emitting carbon quantum dots and their applications for phoxim sensing and cellular imaging(2021/05/24)
作者：Xingyan Huo, Lizhen Liu, Yunfeng Bai
期刊：Analytica Chimica Acta
影响因子 ：6.911
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Ropivacaine suppresses tumour biological characteristics of human hepatocellular carcinoma via inhibiting IGF-1R/PI3K/AKT/mTOR signalling axis(2021/11/22)
作者：Runze Zhang, Yanhong Lian, Kangjie Xie
期刊：Bioengineered
DOI：10.1080/21655979.2021.1995103
影响因子 ：6.8320
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Chrysophanol Induced Glioma Cells Apoptosis via Activation of Mitochondrial Apoptosis Pathway(2021/9/14)
作者：Jia Gu, Sunil Rauniyar, Yan Wang
期刊：Bioengineered
DOI：10.1080/21655979.2021.1972079
影响因子 ：6.8320
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Regulating COX10-AS1 / miR-142-5p / PAICS axis inhibits the proliferation of non-small cell lung cancer(2021/7/29)
作者：Xinyu Tang, YiHe Wu, Jie Yang
期刊：Bioengineered
DOI：10.1080/21655979.2021.1957072
影响因子 ：6.8320
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FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2(2022/10/25)
作者：Meige Sun, Xiaocui Zhang, Fangfang Bi
期刊：Cancers
影响因子 ：6.5750
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PLGA/PCADK composite microspheres containing hyaluronic acid–chitosan siRNA nanoparticles: A rational design for rheumatoid arthritis therapy(2021/01/23)
作者：Menghui Zhao, Tianyu Zhu, Jicong Chen
期刊：International Journal Of Pharmaceutics
DOI：10.1016/j.ijpharm.2021.120204
影响因子 ：6.510
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Delivery of siRNA using folate receptor-targeted pH-sensitive polymeric nanoparticles for rheumatoid arthritis therapy(2019/05/22)
作者：Xiangshi Sun, Shiyan Dong, Xiangyu Li
期刊：Nanomedicine-Nanotechnology Biology and Medicine
DOI：10.1016/j.nano.2019.102017
影响因子 ：6.4580
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Circ-RNF121 regulates tumor progression and glucose metabolism by miR-1224-5p/FOXM1 axis in colorectal cancer(2021/11/06)
作者：Zhipeng Jiang, Hao Hu, Wenli Hu
期刊：Cancer Cell International
DOI：10.1186/s12935-021-02290-3
影响因子 ：6.4290
引用产品：164210 164210-50 CL-0096 CL-0144 CL-0223B CL-0225B PB180120 PM150110 PM150210
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Long non-coding RNA UCA1 relieves cardiomyocytes H9c2 injury aroused by oxygen-glucose deprivation via declining miR-122(2019/12/01)
作者：Zaiwei Zhang
期刊： Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1652630
影响因子 ：6.355
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Emodin protects against lipopolysaccharide-induced inflammatory injury in HaCaT cells through upregulation of miR-21(2019/06/28)
作者：Yanping Song, Xueling Cui, Ruilan Zhao
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1629951
影响因子 ：6.355
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RETRACTED ARTICLE: Bilobalide protects H9c2 cell from oxygen-glucose-deprivation-caused damage via upregulation of miR-27a(2019/07/19)
作者：Ailin Cao, Xiangting Li
期刊： Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1640708
影响因子 ：6.355
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Glutaraldehyde inactivation of enveloped DNA viruses in the preparation of haemoglobin-based oxygen carriers(2017/10/28)
作者：Huiya Ma
期刊： Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2017.1394875
影响因子 ：6.355
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Alantolactone induces apoptosis through ROS-mediated AKT pathway and inhibition of PINK1-mediated mitophagy in human HepG2 cells(2019/05/22)
作者：Xing Kang, Hijuan Wang, Yanwei Li
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1593854
影响因子 ：6.355
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Alantolactone induces apoptosis through ROS-mediated AKT pathway and inhibition of PINK1-mediated mitophagy in human HepG2 cells(2019/05/22)
作者：Xing Kang, Hijuan Wang, Yanwei Li
期刊： Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1593854
影响因子 ：6.355
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6-Gingerols (6G) reduces hypoxia-induced PC-12 cells apoptosis and autophagy through regulation of miR-103/BNIP3(2019/5/2)
作者：Chunyang Kang, Mingyang Kang, Yingying Han
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1606010
影响因子 ：6.3550
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Glutaraldehyde inactivation of enveloped DNA viruses in the preparation of haemoglobin-based oxygen carriers(2017/10/28)
作者：Huiya Ma, Qiuhui Li, Kun Feng
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2017.1394875
影响因子 ：6.3550
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GDF11 Regulates PC12 Neural Stem Cells via ALK5-Dependent PI3K-Akt Signaling Pathway(2022/10/14)
作者：Zongkui Wang, Peng Jiang, Fengjuan Liu
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：6.2080
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Structural Characteristics of Polysaccharide GP2a in Gardenia jasminoides and Its Immunomodulatory Effect on Macrophages(2022/09/24)
作者：Pingdong Lin, Lifei Chen, Xiaojing Huang
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：6.2080
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Hepatocyte-Specific Smad4 Deficiency Alleviates Liver Fibrosis via the p38/p65 Pathway(2022/10/02)
作者：Miaomiao Wei, Xinlong Yan, Xin Xin
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：6.2080
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Epigenetic silencing of microRNA-125b-5p promotes liver fibrosis in nonalcoholic fatty liver disease via integrin α8-mediated activation of RhoA signaling pathway(2020/01/09)
作者：Qingxian Cai, Fengjuan Chen, Fen Xu
期刊：Metabolism
DOI：10.1016/j.metabol.2020.154140
影响因子 ：6.1590
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Novel prognostic matrisome-related gene signature of head and neck squamous cell carcinoma.(2022/08/23)
作者：Chao Huang, Yun Liang, Yi Dong
期刊：Frontiers in Cell and Developmental Biology
影响因子 ：6.0810
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Assessment of the safety and probiotic properties of Roseburia intestinalis: A potential “Next Generation Probiotic”(2022/09/08)
作者：Chao Zhang, Kejia Ma, Kai Nie
期刊：Frontiers in Microbiology
影响因子 ：6.0640
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Effects of Nickel at Environmentally Relevant Concentrations on Human Corneal Epithelial Cells: Oxidative Damage and Cellular Apoptosis(2022/09/12)
作者：Zhenning Zhang, Hai Liu, Mimi Liu
期刊：Biomolecules
影响因子 ：6.0640
-
Effects of novel cellulase (Cel 906) and probiotic yeast fermentation on antioxidant and anti-inflammatory activities of vine tea (Ampelopsis grossedentata).(2022/09/15)
作者：Jin Xu, Mubasher Hussain, Wenfeng Su
期刊：Frontiers in Bioengineering and Biotechnology
DOI：10.3389/fbioe.2022.1006316
影响因子 ：6.0640
-
TMEM16F may be a new therapeutic target for Alzheimer’s disease(2022/08/02)
作者：Zhiqiang Cui, Xiaoying Hu, Tuo Yang
期刊：Neural Regeneration Research
影响因子 ：6.0580
-
microRNA-9 and -29a regulate the progression of diabetic peripheral neuropathy via ISL1-mediated sonic hedgehog signaling pathway(2020/06/16)
作者：Qin Sun, Jun Zeng, Yang Liu
期刊：Aging-US
影响因子 ：5.9550
-
High expression of CCNB1 driven by ncRNAs is associated with a poor prognosis and tumor immune infiltration in breast cancer.(2022/08/29)
作者：Hongtao Fu, Kun Li, Shui Wang
期刊：Aging-US
影响因子 ：5.9550
-
Bioprinting of novel 3D tumor array chip for drug screening(2020/05/19)
作者：Mingjun Xie, Qing Gao, Jianzhong Fu
期刊：Bio-Design and Manufacturing
DOI：10.1007/s42242-020-00078-4
影响因子 ：5.887
-
CircDIP2C ameliorates oxidized low-density lipoprotein-induced cell dysfunction by binding to miR-556-5p to induce TET2 in human umbilical vein endothelial cells(2021/06/18)
作者：Fudong Hu, Xi Chen, Juan Gao
期刊：Vascular Pharmacology
影响因子 ：5.738
-
Circ_0027599 elevates RUNX1 expression via sponging miR-21-5p on gastric cancer progression(2021/05/25)
作者：Jinzhu Han, Zixin Yang, Shan Zhao
期刊：Eur J Clin Invest
影响因子 ：5.722
-
Notoginsenoside R1 induces oxidative stress and modulates LPS induced immune microenvironment of nasopharyngeal carcinoma(2022/10/21)
作者：Siwei Li, Guoliang Pi, Yong Zeng
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2022.109323
影响因子 ：5.7140
-
Senkyunolide I alleviates renal Ischemia-Reperfusion injury by inhibiting oxidative stress, endoplasmic reticulum stress and apoptosis(2021/11/30)
作者：Yalin Zhu, Jie Huang, Xueying Chen
期刊：International Immunopharmacology
DOI：10.1016/j.intimp.2021.108393
影响因子 ：5.7140
-
CircWDR33 alleviates human pulmonary microvascular endothelial cell injury in sepsis-associated acute lung injury by targeting miR-217-5p/SERP1 axis(2022/11/20)
作者：Ting You, Bihong Zhang
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2022.109440
影响因子 ：5.7140
-
LncRNA surfactant associated 1 activates large tumor suppressor kinase 1/Yes-associated protein pathway via modulating hypoxic exosome-delivered miR-4766–5p to inhibit lung adenocarcinoma metastasis(2022/10/22)
作者：Weiqiang Zhang, Miaochun Bai, Keqiang Liu
期刊：INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI：10.1016/j.biocel.2022.106317
影响因子 ：5.6520
-
Study of double-targeting nanoparticles loaded with MCL-1 siRNA and dexamethasone for adjuvant-induced arthritis therapy(2020/07/15)
作者：Xiangyu Li, Changhui Yu, Xiangxue Meng
期刊：European Journal Of Pharmaceutics And Biopharmaceutics
DOI：10.1016/j.ejpb.2020.07.009
影响因子 ：5.589
-
Glutathione-Mediated Clearable Nanoparticles Based on Ultrasmall Gd2O3 for MSOT/CT/MR Imaging Guided Photothermal/Radio Combination Cancer Therapy(2019/6/17)
作者：Yu Cheng, Tong Lu, Yidan Wang
期刊：Molecular Pharmaceutics
DOI：10.1021/acs.molpharmaceut.9b00332
影响因子 ：5.3640
-
Bifidobacterium animalis sup F1-7 Acts as an Effective Activator to Regulate Immune Response Via Casepase-3 and Bak of FAS/CD95 Pathway(2022/08/22)
作者：Youyou Lu, Xi Liang, Yeting Wu
期刊：Probiotics and Antimicrobial Proteins
DOI：10.1007/s12602-022-09975-9
影响因子 ：5.2650
-
Circ_0006988 promotes the proliferation, metastasis and angiogenesis of non-small cell lung cancer cells by modulating miR-491-5p/MAP3K3 axis(2021/06/30)
作者：Chao Yang, Jiang Shi, Jie Wang
期刊：Cell Cycle
DOI：10.1080/15384101.2021.1941612
影响因子 ：5.173
引用产品：164210 164210-50 CL-0165 CL-0496 CL-0519 PB180120 PM150110
-
Mesenchymal stem cell-derived exosome mediated long non-coding RNA KLF3-AS1 represses autophagy and apoptosis of chondrocytes in osteoarthritis(2021/12/29)
作者：Chuanyang Wen, Lupan Lin, Rui Zou
期刊：Cell Cycle
DOI：10.1080/15384101.2021.2019411
影响因子 ：5.1730
-
miR-203 promotes HaCaT cell overproliferation through targeting LXR-α and PPAR-γ(2020/06/28)
作者：Yueyuan Xiao, Haizhen Wang, Chang Wang
期刊：Cell Cycle
DOI：10.1080/15384101.2020.1783934
影响因子 ：5.173
-
Tanshinone IIA exerts beneficial effects on fracture healing in vitro and in vivo(2019/09/01)
作者：Yang Wang, Hongyu Chen, Hanyang Zhang
期刊：Chemico-Biological Interactions
影响因子 ：5.168
-
Circular RNA circ-ERBB2 Elevates the Warburg Effect and Facilitates Triple-Negative Breast Cancer Growth by the MicroRNA 136-5p/Pyruvate Dehydrogenase Kinase 4 Axis | Molecular and Cellular Biology(2021/9/24)
作者：Yihong Huang, Shuo Zheng, Ying Lin, Liming Kea
期刊：Molecular And Cellular Biology
影响因子 ：5.0690
引用产品：164210 CL-0041 CL-0150A CL-0152A CL-0290A CL-0525 PB180120 PM150110 PM151010
-
LINC01146/F11R facilitates growth and metastasis of prostate cancer under the regulation of TGF-β(2022/09/23)
作者：Xiaohua Guo, Yong Gu, Chao Guo
期刊：JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
DOI：10.1016/j.jsbmb.2022.106193
影响因子 ：5.0110
-
Overexpression of ARHI increases the sensitivity of cervical cancer cells to paclitaxel through inducing apoptosis and autophagy(2021/6/30)
作者：Yang Wang, Fangrong Shen, Jinhua Zhou
期刊：Drug Development Research
影响因子 ：5.0040
-
Dictamnine Inhibits the Adhesion to and Invasion of Uropathogenic Escherichia Coli (UPEC) to Urothelial Cells(2022/01/02 )
作者：Wenbo Yang, Peng Liu, Ying Chen
期刊：MOLECULES
影响因子 ：4.9270
-
Isolation of Phenolic Compounds from Raspberry Based on Molecular Imprinting Techniques and Investigation of Their Anti-Alzheimer’s Disease Properties(2022/10/14)
作者：Qian Wu, Abid Naeem, Jiamei Zou
期刊：MOLECULES
影响因子 ：4.9270
-
Anti-Malignant Ascites Effect of Total Diterpenoids from Euphorbiae ebracteolatae Radix Is Attributable to Alterations of Aquaporins via Inhibiting PKC Activity in the Kidney(2021/02/10)
作者：Yuanbin Zhang, Dongfang Liu, Fan Xue
期刊：Molecules
影响因子 ：4.927
-
E3 ubiquitin ligase mind bomb 1 overexpression reduces apoptosis and inflammation of cardiac microvascular endothelial cells in coronary microvascular dysfunction(2021/12/23)
作者：Xiaofei Qin, Yingguang Shan, Jinghong Gao
期刊：Cellular Signalling
DOI：10.1016/j.cellsig.2021.110223
影响因子 ：4.8500
-
Imaging mitochondrial palladium species in living cells with a NIR iridium(III) complex(2022/11/28)
作者：Jingqi Liu, Xueliang Wang, Jing Wang, Chung-Hang Leung, Wanhe Wang
期刊：SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
影响因子 ：4.8310
-
Comprehensive development and validation of gene signature for predicting survival in patients with glioblastoma.(2022/08/10)
作者：Yi Jin, Zhanwang Wang, Kaimin Xiang
期刊：Frontiers in Genetics
影响因子 ：4.7720
-
Nocardia rubra cell-wall skeleton influences the development of cervical carcinoma by promoting the antitumor effect of macrophages and dendritic cells(2022/01/07)
作者：Siyang Zhang, Han Wang, Yisi Liu
期刊：Cancer Medicine
影响因子 ：4.7110
-
Lipid Microparticles Show Similar Efficacy With Lipid Nanoparticles in Delivering mRNA and Preventing Cancer(2022/11/30)
作者：Ji, Afang, Xu, Minghao, Pan, Yunzhi, Diao, Lu, Ma, Lin, Qian, Li, Cheng, Junping, Liu, Mi
期刊：PHARMACEUTICAL RESEARCH
DOI：10.1007/s11095-022-03445-1
影响因子 ：4.5800
-
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis(2022/01/12 )
作者：Jingyong Xu, Yao Li, Zhe Li, Weiwei Shao
期刊：Journal of Oncology
影响因子 ：4.5010
-
Downregulation of FXYD2 Is Associated with Poor Prognosis and Increased Regulatory T Cell Infiltration in Clear Cell Renal Cell Carcinoma(2022/10/19)
作者：Zedan Zhang, Yanlin Tang, Lei Li
期刊：Journal of Immunology Research
影响因子 ：4.4930
-
Brusatol inhibits amyloid‐β‐induced neurotoxicity in U‐251 cells via regulating the Nrf2/HO‐1 pathway(2019/1/10)
作者：Xin Liu, HuaWen Xu, YueQi Zhang
期刊：Journal Of Cellular Biochemistry
影响因子 ：4.4800
-
Cyclic RGD Peptide Targeting Coated Nano Drug Co-Delivery System for Therapeutic Use in Age-Related Macular Degeneration Disease(2020/10/23)
作者：Jiaxin Liu, Lifu Luo, Fei Xu
期刊：Molecules
影响因子 ：4.4110
-
Ginsenoside Rg3 inhibits cell growth, migration and invasion in Caco-2 cells by downregulation of lncRNA CCAT1(2019/01/08)
作者：Jinliang Li, Yuxi Qi
期刊：Experimental and Molecular Pathology
DOI：10.1016/j.yexmp.2019.01.003
影响因子 ：4.401
-
LncRNA MEG3 regulates breast cancer proliferation and apoptosis through miR-141-3p/RBMS3 axis(2021/04/09)
作者：Shiliang Dong, Minrui Ma, Ming Li
期刊：Genomics
DOI：10.1016/j.ygeno.2021.04.015
影响因子 ：4.310
-
Energy metabolism disorders and oxidative stress in the SH-SY5Y cells following PM2.5 air pollution exposure(2022/08/23)
作者：Zhaofei Li, Fengjie Tian, Hongfang Ban
期刊：TOXICOLOGY LETTERS
DOI：10.1016/j.toxlet.2022.08.008
影响因子 ：4.2710
-
Key Role of Pro-inflammatory Cytokines in the Toxic Effect of Fluoride on Hepa1-6 Cells(2020/01/25)
作者：Yan Zhang, Bianhua Zhou, Panpan Tan
期刊：BIOLOGICAL TRACE ELEMENT RESEARCH
DOI：10.1007/s12011-019-01967-1
影响因子 ：4.0810
-
NLRP3 augmented resistance to gemcitabine in triple-negative breast cancer cells via EMT/IL-1β/Wnt/β-catenin signaling pathway(2020/7/31)
作者：Qiao Zheng, Dejiao Yao, Yi Cai
期刊：Bioscience Reports
影响因子 ：3.9760
-
STAT3/SH3PXD2A-AS1/miR-125b/STAT3 positive feedback loop affects psoriasis pathogenesis via regulating human keratinocyte proliferation(2021/5/13)
作者：Zhibo Yang, Zhenping Chen, Chang Wang
期刊：Cytokine
DOI：10.1016/j.cyto.2021.155535
影响因子 ：3.9260
-
Long non-coding RNA MEG3 attends to morphine-mediated autophagyof HT22 cells through modulating ERK pathway(2019/08/21)
作者：Shuibo Gao, Enyao Li, Haixia Gao
期刊：Pharmaceutical Biology
DOI：10.1080/13880209.2019.1651343
影响因子 ：3.889
-
CircZNF644 aggravates lipopolysaccharide-induced HK-2 cell impairment via the miR-140-5p/MLKL axis(2022/08/17)
作者：Jing Xing, Songtao Fan, Hongyang Liu
期刊：JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
DOI：10.1007/s10863-022-09946-3
影响因子 ：3.8530
-
Knockdown of circ_0038467 alleviates lipopolysaccharides-induced 16HBE cell injury by regulating the miR-545-3p/TRAF1 axis in neonatal pneumonia(2022/10/08)
作者：Fang Xia, Long Yang, Xiaofang Zhu
期刊：MICROBIAL PATHOGENESIS
DOI：10.1016/j.micpath.2022.105819
影响因子 ：3.8480
-
Circ_0025039 acts an oncogenic role in the progression of non-small cell lung cancer through miR-636-dependent regulation of CORO1C(2022/01/16)
作者：Lei Wang, Cimei Zeng, Zhongren Chen
期刊：Molecular and Cellular Biochemistry
DOI：10.1007/s11010-021-04320-0
影响因子 ：3.8420
引用产品：164210 164210-50 CL-0016 CL-0122 CL-0165 CL-0249 PB180120 PM150110 PM150910
-
Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer(2022/08/02)
作者：Bo Zhang, Wenbin Cao, Yang Liu
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-022-04525-x
影响因子 ：3.8420
-
circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway(2022/01/06)
作者：Yu Li, Guangle Qin, Jinyun Du
期刊：Journal of Healthcare Engineering
影响因子 ：3.8220
-
MiR-140-5p upregulation suppressed β-glycerophosphate-induced vascular smooth muscle cell calcification via targeting TLR4(2022/03/11)
作者：Fan Zhang,Jingxing Li,Chengxiong Gu
期刊：Immunopharmacology And Immunotoxicology
DOI：10.1080/08923973.2022.2043896
影响因子 ：3.7120
-
Silk sericin/fibroin electrospinning dressings: a method for preparing a dressing material with high moisture vapor transmission rate(2021/07/28)
作者：Nan Lin, Baoqi Zuo
期刊：Journal Of Biomaterials Science-Polymer Edition
DOI：10.1080/09205063.2021.1952383
影响因子 ：3.682
-
EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR(2022/01/17)
作者：Xiaoli Li, Chengmou Wang, Guanghui Chen
期刊： Metabolic Brain Disease
DOI：10.1007/s11011-021-00899-x
影响因子 ：3.6550
引用产品：164210 CL-0012 CL-0237 CL-0238 CL-0583 PB180120 PM150210
-
EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR(2022/01/17)
作者：Xiaoli Li, Chengmou Wang, Guanghui Chen
期刊： Metabolic Brain Disease
DOI：10.1007/s11011-021-00899-x
影响因子 ：3.6550
引用产品：164210 CL-0012 CL-0237 CL-0238 CL-0583 PB180120 PM150210
-
Structural characterization, antioxidant activity, and immunological activity in vitro of polysaccharides from fruiting bodies of Suillus granulatus(2018/01/21)
作者：Shuang Chen,Tingting Su,Zhanyong Wang
期刊：Journal of Food Biochemistry
影响因子 ：3.6540
-
Circular RNA Circ_0006282 Promotes Cell Proliferation and Metastasis in Gastric Cancer by Regulating MicroRNA-144-5p/Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein β Axis(2021/1/27)
作者：Yunqi Hua, Hailong Wang, Haizhen Wang
期刊：Cancer Management and Research
影响因子 ：3.6020
引用产品：164210 164210-50 CL-0022 CL-0107 CL-0563 PB180120 PM150110
-
Circ_0032821 Facilitates Gastric Cancer Cell Proliferation, Migration, Invasion and Glycolysis by Regulating MiR-1236-3p/HMGB1 Axis(2020/10/12)
作者：Lei Chen, Kun Chi, Huaguo Xiang
期刊：Cancer Management and Research
影响因子 ：3.6020
引用产品：164210 164210-50 CL-0022 CL-0107 CL-0169 CL-0292 CL-0563 PB180120 PM150110
-
Circ_0001535 Facilitates Tumor Malignant Progression by miR-485-5p/LASP1 Axis in Colorectal Cancer(2022/11/07)
作者：Liang Bai, Zhifeng Gao, An Jiang, Song Ren, Baotai Wang
期刊：Balkan Medical Journal
DOI：10.4274/balkanmedj.galenos.2022.2022-6-51
影响因子 ：3.5700
-
Overexpression of Stathmin 1 Predicts Poor Prognosis and Promotes Cancer Cell Proliferation and Migration in Ovarian Cancer(2022/02/09)
作者：Lekai Nie, Chen Zhang, Haiyun Song
期刊：Disease Markers
影响因子 ：3.4640
-
The sympathetic transmitter norepinephrine inhibits VSMC proliferation induced by TGFβ by suppressing the expression of the TGFβ receptor ALK5 in aorta remodeling(2020/4/22)
作者：Zhipeng Hu, Bowen Li, Zhiwei Wang
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
Naringin induces apoptosis of gastric carcinoma cells via blocking the PI3K/AKT pathway and activating pro‑death autophagy(2021/9/7)
作者：Cuixiang Xu, Xiaoyan Huang, Yubin Huang
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
Lycium barbarum polysaccharide protects ARPE‑19 cells against H2O2‑induced oxidative stress via the Nrf2/HO‑1 pathway(2021/9/7)
作者：Ran Liang, Qi Zhao, Qing Zhu
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
Methylophiopogonanone B of Radix Ophiopogonis protects cells from H2O2‑induced apoptosis through the NADPH oxidase pathway in HUVECs(2019/8/29)
作者：Liling Wang, Yifeng Zhou, Yuchuan Qin
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
Rosuvastatin protects against oxidized low‑density lipoprotein‑induced endothelial cell injury of atherosclerosis in vitro(2018/11/19)
作者：Jianan Geng, Huali Xu, Xiaofeng Yu
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
Polyaniline promotes peripheral nerve regeneration by enhancement of the brain‑derived neurotrophic factor and ciliary neurotrophic factor expression and activation of the ERK1/2/MAPK signaling pathway(2017/09/20)
作者：Lin Fan, Yan Xiong, Zhen Fu
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
HOXA13 exerts a beneficial effect in albumin-induced epithelial-mesenchymal transition via the glucocorticoid receptor signaling pathway in human renal tubular epithelial cells(2016/05/11)
作者：Li Peng, Qingnan He, Xiaoyan Li
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
Triptolide reduces proliferation and enhances apoptosis of human non-small cell lung cancer cells through PTEN by targeting miR-21(2016/02/02)
作者：Xiaofang Li, Aimin Zang, Youchao Jia
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
Long non‑coding RNA HCG18 facilitates the progression of laryngeal and hypopharyngeal squamous cell carcinoma by upregulating FGFR1 via miR‑133b(2021/12/08)
作者：Hongbin Peng, Pingjiang Ge
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
LOC102553417 silencing facilitates the apoptosis of hepatic stellate cells via the miR‑30e/MTDH axis(2022/09/29)
作者：Wujun Wei, Cheng Lin, Rentong Hu
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
Preparation and characterization of foamy poly(γ-benzyl- l -glutamate- co - l -phenylalanine)/bioglass composite scaffolds for bone tissue engineering(2016/7/18)
作者：Ning Cui, Junmin Qian, Jinlei Wang
期刊：RSC Advances
影响因子 ：3.3610
-
Overexpression of long non-coding RNA XIST promotes IL-1β-induced degeneration of nucleus pulposus cells through targeting miR-499a-5p(2021/3/17)
作者：Jun He, Jing Yang, Tulan Shen
期刊：Molecular And Cellular Probes
影响因子 ：3.2850
-
Blow-Spun Collagen Nanofibrous Spongy Membrane: Preparation and Characterization(2022/01/17)
作者：Jingchuan Zheng, Chunyi Yang, Xiumei Wang
期刊：Tissue Eng Part C Methods
影响因子 ：3.2730
-
Knockdown of Circular Ubiquitin-specific Peptidase 9 X-Linked Alleviates Oxidized Low-density Lipoprotein-induced Injuries of Human Umbilical Vein Endothelial Cells by Mediating the miR-148b-3p/KLF5 Signaling Pathway(2021/12/01)
作者：Xiaowen Jiang, Lei Chen, Hao Wu
期刊：Journal of Cardiovascular Pharmacology
DOI：10.1097/FJC.0000000000001127
影响因子 ：3.2710
-
M2 Macrophage-Derived Exosomes Inhibit Apoptosis of HUVEC Cell through Regulating miR-221-3p Expression(2022/09/07)
作者：Xiandong Cheng, Hong Zhou, Ying Zhou
期刊：Biomed Research International
影响因子 ：3.2460
-
Upregulation of KIF18B facilitates malignant phenotype of esophageal squamous cell carcinoma by activating CDCA8/mTORC1 pathway(2022/09/09)
作者：Jiangliu Xie, Bo Wang, Wenjie Luo
期刊：JOURNAL OF CLINICAL LABORATORY ANALYSIS
影响因子 ：3.1240
-
Articular Cartilage Fragmentation Improves Chondrocyte Migration by Upregulating Membrane Type 1 Matrix Metalloprotease:(2021/10/15)
作者：Yunliang Lei, Jiabin Peng, Zhu Dai
期刊：CARTILAGE
影响因子 ：3.117
-
Nonylphenol promotes the proliferation of colorectal cancer COLO205 cells by upregulating the expression of protein kinase C ζ(2018/12/18)
作者：Xuefeng Yang, Handong Huang, Maijian Wang
期刊：Oncology Letters
影响因子 ：3.1110
-
Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma(2022/01/25)
作者：Xu Qian, Zhongming Bao, Dan Yao
期刊：Kaohsiung Journal of Medical Sciences
影响因子 ：2.9960
-
Circ-METTL15 contributes to the proliferation, metastasis, immune escape and restrains apoptosis in lung cancer by regulating miR-1299/PDL1 axis(2021/11/19)
作者：Rui Zhang, Liang Shang, Jinniang Nan
期刊：Autoimmunity
DOI：10.1080/08916934.2021.2001801
影响因子 ：2.9570
引用产品：164210 164210-50 CL-0016 CL-0165 CL-0166 CL-0229 PB180120 PM150110
-
CircVMA21 ameliorates lipopolysaccharide (LPS)-induced HK-2 cell injury depending on the regulation of miR-7-5p/PPARA(2021/12/13)
作者：Fu Wang, Fangfang Zhang, Qiangqiang Tian
期刊：Autoimmunity
DOI：10.1080/08916934.2021.2012764
影响因子 ：2.9570
-
Enhancing the antibacterial activity of antimicrobial peptide PMAP-37(F34-R) by cholesterol modification(2020/11/02)
作者：Liangliang Chen, Tengfei Shen, Yongqing Liu
期刊：BMC Veterinary Research
DOI：10.1186/s12917-020-02630-x
影响因子 ：2.7920
-
Emodin reverses resistance to gemcitabine in pancreatic cancer by suppressing stemness through regulation of the epithelial‑mesenchymal transition(2022/11/16)
作者：Weitian Wei, Jiangfeng Wang, Yuqian Hu, Sheng Chen, Jinshi Liu
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.7510
-
Apoptotic bodies extracted from adipose mesenchymal stem cells carry microRNA-21–5p to induce M2 polarization of macrophages and augment skin wound healing by targeting KLF6(2022/01/03)
作者：Jianrui Li, Chuanyuan Wei, Yang Yang
期刊：Burns
DOI：10.1016/j.burns.2021.12.010
影响因子 ：2.6090
引用产品：164210 164210-50 CL-0023 CM-M086 CM-M138 CM-M201 CP-M086 CP-M138 CP-M201 PB180120 PM150110
-
Hsa_circ_0074032 promotes prostate cancer progression through elevating homeobox A1 expression by serving as a microRNA-198 decoy(2021/11/19)
作者：Chuanshun Feng, Qinjun Wang, Ling Deng
期刊：Andrologia
影响因子 ：2.5320
引用产品：164210 164210-50 CL-0075 CL-0143 CL-0185 CL-0200 CM-0200 PB180120 PM150110 PM150410 PM150910
-
Heat shock protein 47 promotes cell migration and invasion through AKT signal in non-small cell lung cancer(2022/03/01)
作者：Wei Wu, Zhenzhen Hu, Linkai Xiong
期刊：Anti-Cancer Drugs
DOI：10.1097/CAD.0000000000001262
影响因子 ：2.3890
-
Circ_0000745 regulates NOTCH1-mediated cell proliferation and apoptosis in pediatric T-cell acute lymphoblastic leukemia through adsorbing miR-193b-3p(2021/11/09)
作者：Huanhuan Feng, Fei Li, Ping Tang
期刊：Hematology
DOI：10.1080/16078454.2021.1997197
影响因子 ：2.2640
引用产品：164210 164210-50 CL-0058 CL-0129 CP-H158 PB180120 PM150110
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LncRNA SOX2OT Knockdown Alleviates Lipopolysaccharide-Induced Damage of PC12 Cells by Regulating miR-331-3p/Neurod1 Axis(2020/12/16)
作者：Ronggang Li, Xiaofeng Li, Yong Huang
期刊：World Neurosurgery
DOI：10.1016/j.wneu.2020.12.049
影响因子 ：2.2100
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Knockdown of kinesin family member 2C restricts cell proliferation and induces cell cycle arrest in gastric cancer(2022/11/30)
作者：Shuai Li, Yulian Ma, Chen Wu, Xinfang Hou, Shuai Li, Yulian Ma, Chen Wu, Xinfang Hou
期刊：HISTOLOGY AND HISTOPATHOLOGY
影响因子 ：2.1300
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LncRNA Taurine Up-Regulated 1 plays a proapoptotic role by regulating nuclear-cytoplasmic shuttle of HuR under the condition of neuronal ischemia(2022/10/27)
作者：Xiaocheng Shi, Wei Wei, Yichun Zou
期刊：NEUROREPORT
DOI：10.1097/WNR.0000000000001848
影响因子 ：1.7030
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Saikosaponin D inhibits proliferation and induces apoptosis of non-small cell lung cancer cells by inhibiting the STAT3 pathway(2020/09/22)
作者：Shibo Wu, Weizhuang Chen, Kaitai Liu
期刊：Journal Of International Medical Research
影响因子 ：1.5730
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GATA2/FGF21 Axis Regulates the Effects of High Glucose on the Apoptosis, Autophagy and Oxidative Stress of Human Umbilical Vein Endothelial Cell via PI3K/AKT/mTOR Pathway(2022/03/01)
作者：Jinyan Zheng, Xiaojiang Ma, Yimeng Zhou
期刊：Annals Of Clinical And Laboratory Science
DOI：PMID:35414507
影响因子 ：1.1800
