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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Mouse

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  • Procell-IL-2/ IL2, Mouse, Recombinant

IL-2/ IL2, Mouse, Recombinant

货号:PCK025

价格:¥980¥2980¥17480¥25680

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Aldesleukin; Interleukin 2; Interleukin-2; IL-2; IL2; T-cell Growth Factor; T cell Growth Factor; TCGF
物种 Mouse
表达宿主 E.coli
序列信息 Ala21-Gln169
检索号 P04351
分子量 17.4 kDa
表观分子量 17 kDa
生物活性 Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells.The specific activity of Recombinant Mouse IL-2 is ≥1×10^7 IU/mg.

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM Sodium Citrate, 5% Trehalose, pH4.5.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled waterPlease aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Interleukin 2 (IL 2), also termed T-cell Growth Factor, is a member of the Cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 Receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by Cytokine Receptors of all members of Cytokine family. Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma δ T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key Cytokine in the natural suppression of autoimmunity.
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