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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Mouse

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  • Procell-M-CSF/ CSF1, Mouse, Recombinant

M-CSF/ CSF1, Mouse, Recombinant

货号:PCK043

价格:¥1780¥4980¥18980¥27980

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm
物种 Mouse
表达宿主 Human Cells
序列信息 Lys33-Glu262
检索号 P07141
分子量 26.0 kDa
表观分子量 43 kDa
生物活性 Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cellsThe ED50 for this effect is less than 10 ng/ ml.

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 0.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Macrophage colony-stimulating factor 1 (M-csf)is a single-pass type I membrane Protein . It is a hematopoietic Growth Factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/ macrophage cell lineage. By interacting with its membrane Receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
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