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  • Procell-M-CSF/ CSF1, Rat, Recombinant

M-CSF/ CSF1, Rat, Recombinant

货号:PCK044

价格:¥1780¥4980¥17480¥27980

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Macrophage colony-stimulating factor 1; CSF-1; M-CSF; MCSF; CSF1
物种 Rat
表达宿主 Human Cells
序列信息 Gln33-Arg254
检索号 Q8JZQ0
分子量 25.2 kDa
表观分子量 25.2 kDa
生物活性 Testing in progress

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 In general, recombinant Proteins are provided as lyophilized powder which are shipped at ambient temperature.
制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Rat Macrophage colony-stimulating factor 1 (MCSF,CSF1) is a single-pass type I membrane Cytokine. It is a hematopoietic Growth Factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory Chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipo Protein clearance.
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