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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

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  • Procell-IL-1β/ IL1F2, Human, Recombinant

IL-1β/ IL1F2, Human, Recombinant

货号:PCK047

价格:¥1380¥3680¥17480¥25680

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Interleukin-1 beta; Catabolin; IL1F2; IL1B.
物种 Human
表达宿主 E.coli
序列信息 Ala117-Ser269
检索号 P01584
分子量 17.5 kDa
表观分子量 17 kDa
生物活性 Measured by its ability to induce NFKB reporter gene expression in HEK 293 cell line.The ED50 for this effect is typically 142 pg/ mL

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide Cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast Growth Factor activity. IL-1 Proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
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