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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Rabbit

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  • Procell-TNF-α/ TNFA/ TNFSF2, Rabbit, Recombinant

TNF-α/ TNFA/ TNFSF2, Rabbit, Recombinant

货号:PCK056

价格:¥1480¥3980¥17480¥25680

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor; Membrane Form; Tumor Necrosis Factor; Soluble Form; Tnf; Tnfa; Tnfsf2
物种 Rabbit
表达宿主 E.coli
序列信息 Val77-Leu235
检索号 P04924
分子量 17.59 kDa
表观分子量 18 kDa
生物活性 Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is less than 20 pg/ ml.

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB, 300mM NaCl, pH7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Tumor necrosis factor alpha (TNFα) is the prototypic Ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of Receptors TNF-R1 (TNF Receptor type 1,p55R) and TNF-R2 (TNF Receptor type 2,p75R). TNFα is a pleiotropic Cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
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