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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

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  • Procell-β-NGF/ NGF/ NGFB (Glu19-Ala241), Human, Recombinant

β-NGF/ NGF/ NGFB (Glu19-Ala241), Human, Recombinant

货号:PCK069

价格:¥1380¥3680¥17480¥25680

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB
物种 Human
表达宿主 E.coli
序列信息 Glu19-Ala241
检索号 P01138
分子量 25 kDa
表观分子量 30 kDa
生物活性 Testing in progress

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

The precursor form of the Nerve Growth Factor (proNGF) like its mature form is characterized by the cystin knot Motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin Receptor p75 (p75NTR) and vps10p domain-containing Receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
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