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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

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  • Procell-TGFB1/ TGFβ1/ TGF-β1, Human, Recombinant
  • Procell-TGFB1/ TGFβ1/ TGF-β1, Human, Recombinant

TGFB1/ TGFβ1/ TGF-β1, Human, Recombinant

货号:PCK091

价格:¥1780¥4980¥24080¥35580

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Transforming Growth Factor Beta-1; TGF-Beta-1; Latency-Associated Peptide; LAP; TGFB1; TGFB
物种 Human
表达宿主 CHO Stable Cells
序列信息 Ala279-Ser390
检索号 P01137
分子量 12.8 kDa
表观分子量 13 kDa
生物活性 Measured by its ability to inhibit the IL-4-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is 4-40 pg/ml.

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 <1.0 EU per µg as determined by LAL test.
保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输 Ambient temperature or ice pack.
制剂 Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mMNacl, pH2.5.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
参考文献
文献列表
  • miRNA-181a over-expression in mesenchymal stem cell-derived exosomes influenced inflammatory response after myocardial ischemia-reperfusion injury(2019/7/3)

    作者:Zilun Wei, Shuaihua Qiao, Jinxuan Zhao

    期刊:Life Sciences

    DOI:10.1016/j.lfs.2019.116632

    影响因子 :6.100

    引用产品:PCK091

  • SMAD4 Inhibits Granulosa Cell Apoptosis via the miR-183-96-182 Cluster and FoxO1 Axis(2021/7/21)

    作者:Wang Yao, Siqi Wang, Xing Du

    期刊:Reproductive Sciences

    DOI:10.1007/s43032-021-00690-4.

    影响因子 :2.900

    引用产品:PCK091

  • DNMT3B attenuated the inhibition of TET3 on epithelial-mesenchymal transition in TGF-β1-induced ovarian cancer by methylating the TET3 promoter(2022/10/12)

    作者:Zhongxue Ye, Yafen Jiang, Junlong Wu

    期刊:Reproductive Biology

    DOI:10.1016/j.repbio.2022.100701

    影响因子 :2.100

    引用产品:PCK091

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