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  • Procell-APRIL/ TNFSF13/ TRDL-1α (N-Flag-His), Human, Recombinant

APRIL/ TNFSF13/ TRDL-1α (N-Flag-His), Human, Recombinant

货号:PCK107

价格:¥4880¥7880¥39980¥68880

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Tumor necrosis factor Ligand superfamily member 13; A proliferation-inducing Ligand; APRIL; TNF- and APOL-related leukocyte expressed Ligand 2; TALL-2; TNF-related death Ligand 1; TRDL-1; CD256; TNFSF13
物种 Human
表达宿主 Human Cells
序列信息 Lys112-Leu250
检索号 O75888
分子量 50 kDa
表观分子量 60 kDa
生物活性 Testing in progress

产品特性

纯度 >90% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
复融 Dissolve the lyophilized protein in distilled water. ??

背景介绍

APRIL (a proliferation-inducingLigand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF Ligand superfamily. It issynthesized as a32 kDa pro Protein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule.Secreted human APRIL, which consists almost entirely ofa single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. BothAPRIL and its close relative BAFF bind and signalthrough the TNF superfamily Receptors TACI and BCMA, while BAFF additionally functions through BAFF R.APRIL binds to heparan sulfateproteoglycans (HSPGs) independently of its binding to TACI and BCMA.
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