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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

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  • Procell-FGF-8/ AIGF (N-6His), Human, Recombinant

FGF-8/ AIGF (N-6His), Human, Recombinant

货号:PCK137

价格:¥1380¥3680¥17480¥25680

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Fibroblast Growth Factor 8; Androgen-induced Growth Factor; Heparin-binding Growth Factor 8; AIGF; HBGF-8; FGF-8B
物种 Human
表达宿主 E.coli
序列信息 Gln23-Arg244
检索号 P55075-4
分子量 27.7 kDa
表观分子量 30 kDa
标签 N-6His
生物活性 Measured in a cell proliferation assay using BALB/ c 3T3 cells.The ED50 for this effect is less than 0.5 ug/ ml.

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, 1mM DTT,pH 7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Fibroblast Growth Factor 8 (FGF-8) is a member of the fibroblast Growth Factor family. It is discovered as a Growth Factor essential for the androgen--dependent growth of mouse mammary carcinoma cells. Mouse FGF-8b shares 100% aa identity with human FGF-8b. FGF-8 is widely expressed during embryogenesis, and mediates epithelial--mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
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