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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

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  • Procell-IL-15RA/ CD215 (C-Fc), Human, Recombinant

IL-15RA/ CD215 (C-Fc), Human, Recombinant

货号:PCK149

价格:¥1780¥4980¥18980¥27980

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 CD215; IL15RA; CD215 antigen; IL-15 Receptor subunit alpha; IL-15RA; IL-15R-alpha; Interleukin 15 Receptor; alpha; Interleukin-15 Receptor subunit alpha; MGC104179
物种 Human
表达宿主 Human Cells
序列信息 Ile31-Thr205
检索号 Q13261
分子量 45.5 kDa
表观分子量 36-50 kDa
标签 C-Fc
生物活性 Measured by its ability to block human IL-15-induced proliferation of CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is less than 10 ng/ ml.

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glyco Protein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” Cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/ IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 Receptor β and γ heterodimers and enables signaling to cells.
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