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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

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  • Procell-ST2/ IL1RL1, Human, Recombinant

ST2/ IL1RL1, Human, Recombinant

货号:PCK167

价格:¥780¥1380¥7880¥12380

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Interleukin-1 Receptor-like 1; Protein ST2; DER4; ST2; T1
物种 Human
表达宿主 Human Cells
序列信息 Lys19-Phe328
检索号 Q01638-2
分子量 36.0 kDa
表观分子量 60 kDa
标签 C-6His
生物活性 Measured by its binding ability in a functional ELISA. 2. Immobilized recombinant human IL33 at 10 μg/ mL (100 μl/ well) can bind biotinylated human IL1RL1 (isoform A) with a linear range of 0.032-8 μg/ ml.

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Interleukin 1 Receptor-like 1 (IL1RL1) is a member of the Interleukin-1 Receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a Receptor for Interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ ERK1 and/ or MAPK1/ ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 Cytokine production, it directly implicated in the progression of cardiac disease.
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