全国免费热线:400 650 3656

您身边的细胞培养专家!

忘记密码

个人邮箱:
验证码: captcha

账号激活

个人邮箱:
×
当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

产品中心Cell Resources

联系我们CONTACT US

  • Procell-IL-37, Human, Recombinant

IL-37, Human, Recombinant

货号:PCK196

价格:¥1780¥4980¥17480¥25680

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Interleukin-37; FIL1 Zeta; IL-1X; Interleukin-1 Family Member 7; IL-1F7; Interleukin-1 Homolog 4; IL-1H; IL-1H4; Interleukin-1 Zeta; IL-1 Zeta; Interleukin-1-Related Protein; IL-1RP1; Interleukin-23; IL-37; IL37; FIL1Z; IL1F7; IL1H4; IL1RP1
物种 Human
表达宿主 E.coli
序列信息 Lys53-Asp218
检索号 Q9NZH6
分子量 18.7 kDa
表观分子量 18 kDa
生物活性 Measured by its ability to bind Human IL-18R beta in functional ELISA. The ED50 for this effect is less than 10 ug/ ml.

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM DTT, pH 7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Human Interleukin family 1 Member 7 (IL1F7) is a member of the Interleukin 1 Cytokine family. Five alternatively spliced transcript variants encoding distinct isoforms have been reported with distinct expression profiles. The longest IL1F7 transcript, referred to as IL1F7b or IL1F7 isoform 1, encodes a 218 amino acid residues pro Protein containing a 45 amino acid propeptide, which is cleaved to generate mature Protein. IL1F7b binds to IL18 Rα with low affinity but does not exert any IL18 agonistic or antagonistic effects. IL1F7b also binds Interleukin 18 binding Protein (IL-18BP), an inhibitory binding Protein of Interleukin 18 (IL-18), and subsequently forms a complex with IL18 Receptor beta subunit, and through which it inhibits the activity of IL-18.
朱莎莉

朱莎莉

【 湖北、河南 】

刘本佳

刘本佳

【 江苏、上海、安徽 】

章臣雄

章臣雄

【 广东、广西、贵州、云南 】

閤春喜

閤春喜

【 四川、重庆、陕西、甘肃、西藏 】

石文平

石文平

【 北京、黑龙江、吉林、辽宁 】

任施博

任施博

【 江西、福建、新疆、海南 】

李荣枫

李荣枫

【 天津、河北、内蒙古、山西 】

陈雨兰

陈雨兰

【 湖南、山东、宁夏、青海 】

田庆如

田庆如

【浙江】

黄龄

黄玲

【 山东、湖南、四川、陕西、甘肃、重庆、西藏、浙江 】

李欢欢

李欢欢

【 广东、广西、贵州、云南、江苏、安徽、上海 】

尤会杰

尤会杰

【 河北、山西、天津、内蒙古、福建、海南、江西、新疆、宁夏、青海 】

卢丽丽

卢丽丽

【 湖北、河南、北京、辽宁、吉林、黑龙江 】