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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

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  • Procell-TNF-R2/ CD120b/ TNFRSF1B (C-mFc), Human, Recombinant

TNF-R2/ CD120b/ TNFRSF1B (C-mFc), Human, Recombinant

货号:PCK218

价格:¥1380¥3680¥17480¥25680

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Tumor necrosis factor Receptor superfamily member 1B; TNFRSF1B; Tumor necrosis factorReceptor 2; TNF-R2; TNF-RII; Tumor necrosis factor Receptor type II; p75; p80 TNF-alphaReceptor; CD120b
物种 Human
表达宿主 Human Cells
序列信息 Pro24-Thr206
检索号 P20333
分子量 46.5 kDa
表观分子量 60 kDa
生物活性 Testing in progress

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
复融 Dissolve the lyophilized protein in distilled water. ??

背景介绍

Tumor necrosis factor Receptor superfamily member 1B (TNFRSF1B) is a member of the tumor necrosisfactor Receptor superfamily. Human TNF RII contains four cysteinerich repeats in its ECD, which shares 58%and 56% amino acid sequence identity with the mouse and rat orthologs, respectively.TNF RII is expressedpredominantly on cells of the hematopoietic lineage, such as T and natural killer cells, as well as onendothelial cells, microglia, astrocytes,neurons, oligodendrocytes, cardiac myocytes, thymocytes, andmesenchymal stem cells.TNF RII binds to the membranebound forms of TNFα and Lymphotoxinα/ TNFβ;soluble TNF is thought to signal predominately through TNF RI.Soluble TNF RII is believed to inhibit TNFbiological activity by binding TNF thereby preventing it from activating membrane TNF Receptors.
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