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  • Procell-MIP-1γ/ CCL9, Mouse, Recombinant

MIP-1γ/ CCL9, Mouse, Recombinant

货号:PCK232

价格:¥1380¥3680¥17480¥25680

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 C-C Motif Chemokine 9; CCF18; Macrophage inflammatory Protein 1-gamma; Macrophage inflammatory Protein-related Protein 2; Small-inducible Cytokine A9; Scya10; Scya9 and CCL9.
物种 Mouse
表达宿主 E.coli
序列信息 Gln22-Gln122
检索号 P51670
分子量 11.6 kDa
表观分子量 15 kDa
生物活性 Testing in progress

产品特性

纯度 >90% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl,300mM NaCl,pH8.0.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

C-C Motif Chemokine 9 (CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of Chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and Chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity Receptor,it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its Receptor CCR1 (the most abundant Chemokine Receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.
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