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  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)

KGN (人卵巢颗粒细胞) (STR鉴定正确)

货号:CL-0603

规格:1×10⁶cells/T25培养瓶

价格: ¥2200

生长培养基:DMEM/F1210% FBS1% P/S

数量: - +

  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)
  • KGN (人卵巢颗粒细胞) (STR鉴定正确)

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产品概述
产品信息
名称 KGN (人卵巢颗粒细胞) (STR鉴定正确)
种属
生长特性 贴壁细胞
细胞形态 成纤维细胞样
冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
培养方案A(默认)
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
推荐传代比例 1:2-1:4
推荐换液频率 2-3次/周
参考资料(来源文献)
背景描述 Granulosa cell tumor. Possible to produce progesterone after HCG addition. Cell growth is slow.
年龄(性别) 女性;69岁
组织来源 卵巢,腹膜
细胞类型 肿瘤细胞
肿瘤类型 卵巢癌细胞
生物安全等级 BSL-1
倍增时间 ~46 hours
STR鉴定
  • STR位点信息
    Amelogenin X
    CSF1PO 10,12
    D2S1338 25
    D3S1358 15,17
    D5S818 13
    D7S820 11
    D8S1179 13,14
    D13S317 9
    D16S539 10,12
    D18S51 12,14
    D19S433 13,15.2
    D21S11 30,32.2
    FGA 25,26
    PentaD 10,13
    PentaE 12,21
    TH01 9
    TPOX 8,9
    vWA 17
    D6S1043 13,20
    D12S391 19,21
    D2S441 10,12
  • STR鉴定图
参考文献
文献列表
  • Advanced oxidation protein products attenuate the autophagy-lysosome pathway in ovarian granulosa cells by modulating the ROS-dependent mTOR-TFEB pathway(2024/02/21)

    作者:Xingyu Zhou, Yunhui Lai, Jun Zhang

    期刊:Cell Death & Disease

    DOI:10.1038/s41419-024-06540-w

    影响因子 :9.000

    引用产品:CL-0603

  • Perfluorooctane sulfonate (PFOS) induces apoptosis and autophagy by inhibition of PI3K/AKT/mTOR pathway in human granulosa cell line KGN(2024/01/09)

    作者:Min Gao, Haofei Shen, Qiuyuan Li

    期刊:ENVIRONMENTAL POLLUTION

    DOI:10.1016/j.envpol.2024.123333

    影响因子 :8.900

    引用产品:CL-0603

  • SMAD4-induced knockdown of the antisense long noncoding RNA BRE-AS contributes to granulosa cell apoptosis(2021/05/14)

    作者:Wang Yao, Xing Du, Jinbi Zhang

    期刊:Molecular Therapy-Nucleic Acids

    DOI:10.1016/j.omtn.2021.05.006

    影响因子 :8.800

    引用产品:CL-0603

  • The mechanism of curcumin to protect mouse ovaries from oxidative damage by regulating AMPK/mTOR mediated autophagy(2024/02/24)

    作者:Hongwei Duan, Shanshan Yang, Shuai Yang

    期刊:PHYTOMEDICINE

    DOI:10.1016/j.phymed.2024.155468

    影响因子 :7.900

    引用产品:CL-0603

  • Berberine alleviates inflammation in polycystic ovary syndrome by inhibiting hyaluronan synthase 2 expression(2024/02/15)

    作者:Shaojing He, Hui Li, Qianjie Zhang

    期刊:PHYTOMEDICINE

    DOI:10.1016/j.phymed.2024.155456

    影响因子 :7.900

    引用产品:CL-0603

  • The Release of Peripheral Immune Inflammatory Cytokines Promote an Inflammatory Cascade in PCOS Patients via Altering the Follicular Microenvironment(2021/05/17)

    作者:Yishan Liu, Hao Liu, Zitao Li

    期刊:Frontiers in Immunology

    DOI:10.3389/fimmu.2021.685724

    影响因子 :7.300

    引用产品:CL-0603

  • Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance(2024/01/19)

    作者:Mengting Xu, Fang Li, XiaoYan Xu

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2024.115989

    影响因子 :6.800

    引用产品:CL-0603

  • Exposure to bisphenol A affects transcriptome-wide N6-methyladenine methylation in ovarian granulosa cells(2024/02/13)

    作者:Yuxia Zhang, Congcong Yan, Qian Xie

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2024.116071

    影响因子 :6.800

    引用产品:CL-0603

  • Activation of the p62-Keap1-Nrf2 pathway protects against oxidative stress and excessive autophagy in ovarian granulosa cells to attenuate DEHP-induced ovarian impairment in mice(2023/09/28)

    作者:Bo Xu, Tiantian He, Hong Yang

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2023.115534

    影响因子 :6.800

    引用产品:CL-0603

  • Single-nucleus RNA Sequencing reveals the mechanism of cigarette smoke exposure on diminished ovarian reserve in mice(2022/09/16)

    作者:Fang Li, Ying Wang, Mengting Xu

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2022.114093

    影响因子 :6.800

    引用产品:CL-0603

  • FGF2 Rescued Cisplatin-Injured Granulosa Cells through the NRF2-Autophagy Pathway(2023/09/18)

    作者:Lihui Wang, Feiyan Cheng, Rumeng Pan

    期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

    DOI:10.3390/ijms241814215

    影响因子 :5.600

    引用产品:CL-0603 PM150312

  • Circadian Clock Genes REV-ERBs Inhibits Granulosa Cells Apoptosis by Regulating Mitochondrial Biogenesis and Autophagy in Polycystic Ovary Syndrome(2021/08/05)

    作者:Lihua Sun, Hui Tian, Songguo Xue

    期刊:Frontiers in Cell and Developmental Biology

    DOI:10.3389/fcell.2021.658112

    影响因子 :5.500

    引用产品:CL-0603

  • Inhibition of cisplatin-induced Acsl4-mediated ferroptosis alleviated ovarian injury(2023/12/05)

    作者:Siyuan Wang, Xuqing Li, Jun Li

    期刊:CHEMICO-BIOLOGICAL INTERACTIONS

    DOI:10.1016/j.cbi.2023.110825

    影响因子 :5.100

    引用产品:CL-0603

  • MiR-1224-5p attenuates polycystic ovary syndrome through inhibiting NOD-like receptor protein 3 inflammasome activation via targeting Forkhead box O 1(2021/10/21)

    作者:Yan Li, Nianling Yao, Yan Gao

    期刊:Bioengineered

    DOI:10.1080/21655979.2021.1987125

    影响因子 :4.900

    引用产品:CL-0603 PM150312

  • Kurarinone attenuates hydrogen peroxide-induced oxidative stress and apoptosis through activating the PI3K/Akt signaling by upregulating IGF1 expression in human ovarian granulosa cells(2022/09/17)

    作者:Weiwei Li, Xiurong Yin, Yani Yan

    期刊:ENVIRONMENTAL TOXICOLOGY

    DOI:10.1002/tox.23659

    影响因子 :4.500

    引用产品:CL-0603

  • 25(OH)D3 improves granulosa cell proliferation and IVF pregnancy outcomes in patients with endometriosis by increasing G2M+S phase cells(2023/12/05)

    作者:Rui Hu, Leilei Li, Lanlan Liang

    期刊:Reproductive Biology and Endocrinology

    DOI:10.1186/s12958-023-01165-8

    影响因子 :4.400

    引用产品:CL-0603

  • BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment(2023/10/18)

    作者:Ran Gu, Fangfang Dai, Chunrong Xiang

    期刊:JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

    DOI:10.1016/j.jsbmb.2023.106410

    影响因子 :4.100

    引用产品:CL-0603

  • Design, synthesis and biological evaluation of rhein–piperazine–furanone hybrids as potential anticancer agents(2024/02/13)

    作者:Yu He, Sisi Zhang, Mengxue Wei

    期刊:RSC Medicinal Chemistry

    DOI:10.1039/D3MD00619K

    影响因子 :4.100

    引用产品:CL-0603

  • DNA Methylation Profiles of Ovarian Granular Cells from Fluorosis Female Patients Suffering Reproductive Dysfunctions(2021/10/22)

    作者:Biqi He, Siyuan Dong, Qun Chen

    期刊:Biological Trace Element Research

    DOI:10.1007/s12011-021-02954-1

    影响因子 :4.081

    引用产品:CL-0603

  • Roles of follicle stimulating hormone and sphingosine 1-phosphate co-administered in the process in mouse ovarian vitrification and transplantation(2023/08/24)

    作者:Fei Wang, Yuan Tian, Liwen Huang

    期刊:Journal of Ovarian Research

    DOI:10.1186/s13048-023-01206-1

    影响因子 :4.000

    引用产品:CL-0603

  • GIMAP7 induces oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inhibiting sonic hedgehog signalling pathway(2022/12/30)

    作者:Anran Xu, Yuanyuan Fan, Song Liu

    期刊:Journal of Ovarian Research

    DOI:10.1186/s13048-022-01092-z

    影响因子 :4.000

    引用产品:CL-0603

  • Exosomes derived from bone marrow mesenchymal stem cells attenuate NLRP3 related pyroptosis in autoimmune premature ovarian insufficiency via NF-κB pathway(2024/01/09)

    作者:Jiaxin Xie, Yutao Yang, Aiping Zhuo

    期刊:REPRODUCTIVE BIOMEDICINE ONLINE

    DOI:10.1016/j.rbmo.2024.103814

    影响因子 :4.000

    引用产品:CL-0603

  • miR-21-loaded BMSC-derived Exosomes repair ovarian function of autoimmune premature ovarian insufficiency by targeting MSX1(2024/01/09)

    作者:Yutao Yang, Lichao Tang, Yuanling Xiao

    期刊:REPRODUCTIVE BIOMEDICINE ONLINE

    DOI:10.1016/j.rbmo.2024.103815

    影响因子 :4.000

    引用产品:CL-0603

  • miR-378d is Involved in the Regulation of Apoptosis and Autophagy of and E 2 Secretion from Cultured Ovarian Granular Cells Treated by Sodium Fluoride(2021/01/06)

    作者:Qun Chen, Zhen Li, Zhao Xu

    期刊:BIOLOGICAL TRACE ELEMENT RESEARCH

    DOI:10.1007/s12011-020-02524-x

    影响因子 :3.900

    引用产品:CL-0603

  • Pterostilbene ameliorates oxidative damage and ferroptosis in human ovarian granulosa cells by regulating the Nrf2/HO-1 pathway(2023/03/09)

    作者:Xin Chen, Qian Lin Song, Ze Hong Li

    期刊:Archives Of Biochemistry And Biophysics

    DOI:10.1016/j.abb.2023.109561

    影响因子 :3.900

    引用产品:CL-0527 CL-0603

  • Baicalin suppress the development of polycystic ovary syndrome via regulating the miR-874-3p/FOXO3 and miR-144/FOXO1 axis(2023/06/05)

    作者:Xiaoyuan Xu, Xiaohua Xu, Xiaoshuang Wang

    期刊:PHARMACEUTICAL BIOLOGY

    DOI:10.1080/13880209.2023.2208636

    影响因子 :3.800

    引用产品:CL-0603

  • PDE4 inhibitor Roflumilast modulates inflammation and lipid accumulation in PCOS mice to improve ovarian function and reduce DHEA-induced granulosa cell apoptosis in vitro(2023/01/09)

    作者:Xiaowei Ji, Yao Ye, Lin Wang

    期刊:DRUG DEVELOPMENT RESEARCH

    DOI:10.1002/ddr.22027

    影响因子 :3.800

    引用产品:CL-0603

  • Whole exome sequencing reveals novel variants associated with diminished ovarian reserve in young women(2023/03/29)

    作者:Na Li, Wanxue Xu, Huimin Liu

    期刊:Frontiers in Genetics

    DOI:10.3389/fgene.2023.1154067

    影响因子 :3.700

    引用产品:CL-0603

  • The cytokine profiles in follicular fluid and reproductive outcomes in women with endometriosis(2022/10/26)

    作者:Mutian Han, Wei Cheng, Rui Zhu

    期刊:AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

    DOI:10.1111/aji.13633

    影响因子 :3.600

    引用产品:CL-0603

  • Identification of nonfunctional PABPC1L causing oocyte maturation abnormalities and early embryonic arrest in female primary infertility(2023/09/18)

    作者:Xiang Wang, Ruixi Zhou, Xiaowei Lu

    期刊:CLINICAL GENETICS

    DOI:10.1111/cge.14425

    影响因子 :3.500

    引用产品:CL-0603

  • Excessive fluoride induces ovarian function impairment by regulating levels of ferroptosis in fluorosis women and ovarian granulosa cells(2024/02/09)

    作者:Nan Geng, Siyuan Dong, Pengpeng Xie

    期刊:REPRODUCTIVE TOXICOLOGY

    DOI:10.1016/j.reprotox.2024.108556

    影响因子 :3.300

    引用产品:CL-0603

  • SOX4 regulates proliferation and apoptosis of human ovarian granulosa-like tumor cell line KGN through the Hippo pathway(2024/02/27)

    作者:Qiang Hong, Mengmeng Fan, Rui Cai

    期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

    DOI:10.1016/j.bbrc.2024.149738

    影响因子 :3.100

    引用产品:CL-0603

  • Kisspeptin regulates the proliferation and apoptosis of ovary granulosa cells in polycystic ovary syndrome by modulating the PI3K/AKT/ERK signalling pathway(2023/01/11)

    作者:Pingping Sun, Yuemin Zhang, Lilan Sun

    期刊:BMC Womens Health

    DOI:10.1186/s12905-022-02154-6

    影响因子 :2.500

    引用产品:CL-0603

  • CircRNA circ_0043533 facilitates cell growth in polycystic ovary syndrome by targeting miR-1179(2022/03/25)

    作者:Aixue Chen, Ruiying Jin, Weimei Zho

    期刊:Reproductive Biology

    DOI:10.1016/j.repbio.2022.100637

    影响因子 :2.100

    引用产品:CL-0527 CL-0603

  • KLF4 overexpression facilitates proliferation and represses apoptosis of granulosa cells in polycystic ovary syndrome(2023/06/27)

    作者:Hui Miao, Congxiu Miao, Na Li

    期刊:Molecular & Cellular Toxicology

    DOI:10.1007/s13273-023-00354-1

    影响因子 :1.700

    引用产品:CL-0603

  • Lycopene mitigates DHT-induced apoptosis and oxidative stress in human granulosa cell line KGN by regulating the Nrf2 pathway(2024/02/05)

    作者:Yue Chen, Mengmeng Zhao, Xiaoqing Li

    期刊:Molecular & Cellular Toxicology

    DOI:10.1007/s13273-023-00419-1

    影响因子 :1.700

    引用产品:CL-0603

  • Quercetin and tanshinone prevent mitochondria from oxidation and autophagy to inhibit KGN cell apoptosis through the SIRT1/SIRT3-FOXO3a axis(2024/02/29)

    作者:Qingzhi Wan, Lisha Tang, Kaili Jin

    期刊:CELLULAR AND MOLECULAR BIOLOGY

    DOI:10.14715/cmb/2024.70.2.36

    影响因子 :1.600

    引用产品:CL-0603

  • The E3 Ubiquitin Ligase SYVN1 Plays an Antiapoptotic Role in Polycystic Ovary Syndrome by Regulating Mitochondrial Fission(2022/09/19)

    作者:Lihua Sun, Hongjuan Ye, Hui Tian

    期刊:Oxidative Medicine and Cellular Longevity

    DOI:10.1155/2022/3639302

    影响因子 :0.000

    引用产品:CL-0603

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