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  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)

4T1(小鼠乳腺癌细胞) (STR鉴定正确)

货号:CL-0007

规格:1×10⁶cells/T25培养瓶

价格: ¥1600

生长培养基:RPMI-164010% FBS1% P/S

数量: - +

  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • 4T1(小鼠乳腺癌细胞) (STR鉴定正确)

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4T1(小鼠乳腺癌细胞) (STR鉴定正确) 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
  • ¥1600
4T1细胞专用培养基 4T1细胞专用培养基
  • ¥350
  • ¥450

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产品概述
产品信息
名称 4T1(小鼠乳腺癌细胞) (STR鉴定正确)
别称 4T1-A
背景描述 4T1细胞是从410.4瘤株中未经诱变筛得的6-硫鸟嘌噙抗性细胞株。当4T1细胞注射到BALB/c小鼠中时,4T1细胞会自发产生高转移肿瘤,可转移到肺、肝、淋巴结和大脑,同时在注射部位形成始发灶,诱导转移时不需要摘除始发灶。4T1细胞在BALB/c小鼠中的生长与转移特性与人体中的乳腺癌十分相近,这种肿瘤是人Ⅵ期乳腺癌的动物模型。4T1细胞诱导的肿瘤在手术后及未手术情况下转移的动力学相近,可以用作手术后及未手术模型。4T1细胞诱导的肿瘤模型跟其他肿瘤模型相比,由于4T1细胞的抗6-硫鸟嘌噙特性,微小的转移细胞团(少到仅仅1个)也可以在许多远端器官中检测到,没必要数淋巴结或称重器官。
种属 小鼠
组织来源 乳腺组织
生长特性 贴壁细胞
细胞形态 上皮细胞样
细胞类型 肿瘤细胞
肿瘤类型 乳腺癌细胞
生物安全等级 1
生长培养基 RPMI-164010% FBS1% P/S
推荐传代比例 1:3-1:4
推荐换液频率 2~3次/周
冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
培养条件 气相:空气,95%;CO2,5% 温度:37℃
致瘤性 Yes, forms tumors and metastasizes in BALB/c mice.
保藏机构 ATCC; CRL-2539
STR鉴定
  • STR位点信息
    18-3 18,19
    6-7 12,12
    5-5 14,14
    X-1 24,25
    1-2 17,17
    7-1 25.2,25.2
    8-1 13,13
    1-1 16,16
    19-2 13,13
    15-3 22.3,22.3
    12-1 16,17
    6-4 18,18
    4-2 21.3,21.3
    3-2 14,15
    2-1 16,17
    13-1 16.2,16.2
    11-2 18,19
    17-2 15,15
  • STR鉴定图
参考文献
文献列表
  • 9,10-Phenanthrenequinone: A Promising Kernel to Develop Multifunctional Antitumor Systems for Efficient Type I Photodynamic and Photothermal Synergistic Therapy(2021/11/30)

    作者:Jingjing Guo, Jun Dai, Xiaoluo Peng

    期刊:ACS Nano

    DOI:10.1021/acsnano.1c07730

    影响因子 :18.0270

    引用产品:CL-0007

  • A photoresponsive and rod-shape nanocarrier: Single wavelength of light triggered photothermal and photodynamic therapy based on AuNRs-capped & Ce6-doped mesoporous silica nanorods(2017/04/01)

    作者:Qi Sun, Qing You, Xiaojuan

    期刊:Biomaterials

    DOI:10.1016/j.biomaterials.2017.01.021

    影响因子 :15.304

    引用产品:CL-0007

  • Image-Guided TME-Improving Nano-Platform for Ca2+ Signal Disturbance and Enhanced Tumor PDT(2021/6/24)

    作者:Yuping Jiang, Wei Meng, Lijuan Wu

    期刊:Advanced Healthcare Materials

    DOI:10.1002/adhm.202100789

    影响因子 :11.0920

    引用产品:CL-0007

  • Hollow Au–Cu Nanocomposite for Real-Time Tracing Photothermal/Antiangiogenic Therapy(2017/5/2)

    作者:Xiaojuan Pang, Xiaoxiao Tan, Jinping Wang

    期刊:Advanced Healthcare Materials

    DOI:10.1002/adhm.201700099

    影响因子 :11.0920

    引用产品:CL-0007 CL-0122

  • Cell-penetrating corosolic acid liposome as a functional carrier for delivering chemotherapeutic drugs(2020/02/17)

    作者:Xuqian Li, Andy Samuel Widjaya, Jingxuan Liu

    期刊:Acta Biomaterialia

    DOI:10.1016/j.actbio.2020.02.013

    影响因子 :10.6330

    引用产品:CL-0007 CL-0190

  • BSA–Bioinspired Gadolinium Hybrid-Functionalized Hollow Gold Nanoshells for NIRF/PA/CT/MR Quadmodal Diagnostic Imaging-Guided Photothermal/Photodynamic Cancer Therapy(2017/10/31)

    作者:Qing You, Qi Sun, Meng Yu

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.7b11926

    影响因子 :10.3830

    引用产品:CL-0007

  • Injectable, Biodegradable, Thermosensitive Nanoparticles-Aggregated Hydrogel with Tumor-Specific Targeting, Penetration, and Release for Efficient Postsurgical Prevention of Tumor Recurrence(2019/05/09)

    作者:Huiming Liu, Xiaoguang Shi, Di Wu

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.9b01987

    影响因子 :10.3830

    引用产品:CL-0007

  • RETURN TO ISSUEPREVRESEARCH ARTICLENEXTInjectable, Biodegradable, Thermosensitive Nanoparticles-Aggregated Hydrogel with Tumor-Specific Targeting, Penetration, and Release for Efficient Postsurgical Prevention of Tumor Recurrence(2019/05/09)

    作者:Huiming Liu, Xiaoguang Shi, Di Wu, Frewein Kahsay Khshen

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.9b01987

    影响因子 :10.383

    引用产品:CL-0007

  • Self-Assembly of an Antitumor Dipeptide Induced Near-Infrared Fluorescence and Improved Stability for Theranostic Applications(2021/07/06)

    作者:Weifeng Lin, Yingchun Yang, Yang Lei

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.1c07983

    影响因子 :10.3830

    引用产品:CL-0007 CL-0101

  • Persistent Luminescence Nanoplatform with Fenton-like Catalytic Activity for Tumor Multimodal Imaging and Photoenhanced Combination Therapy(2020/05/15)

    作者:Shuqi Wu, Zihan Qiao, Yang Li

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.0c04438

    影响因子 :10.3830

    引用产品:CL-0005 CL-0007

  • MSOT/CT/MR imaging-guided and hypoxia-maneuvered oxygen self-supply radiotherapy based on one-pot MnO2-mSiO2@Au nanoparticles(2019/03/28)

    作者:Siyu Wang, Qing You, Jinping Wang

    期刊:Nanoscale

    DOI:10.1039/c9nr00918c

    影响因子 :8.307

    引用产品:CL-0007

  • A single-light triggered and dual-imaging guided multifunctional platform for combined photothermal and photodynamic therapy based on TD-controlled and ICG-loaded CuS@mSiO2(2016/12/22)

    作者:Qing You, Qi Sun, Jinping Wang

    期刊:Nanoscale

    DOI:10.1039/C6NR09042G

    影响因子 :8.307

    引用产品:CL-0007

  • A triple-synergistic strategy for combinational photo/radiotherapy and multi-modality imaging based on hyaluronic acid-hybridized polyaniline-coated WS2 nanodots(2017/03/28)

    作者:Jinping Wang, Xiaojuan Pang, Xiaoxiao Tan

    期刊:Nanoscale

    DOI:10.1039/C6NR09219E

    影响因子 :8.307

    引用产品:CL-0007

  • MSOT/CT/MR imaging-guided and hypoxia-maneuvered oxygen self-supply radiotherapy based on one-pot MnO2 -mSiO2 @ Au nanoparticle(2019/03/04)

    作者:Siyu Wang , Qing You , Jinping Wang

    期刊:Nanoscale

    DOI:10.1039/C9NR00918C

    影响因子 :8.307

    引用产品:164210 164210-50 CL-0007 PB180120 PM150210

  • A tungsten nitride-based degradable nanoplatform for dual-modal image-guided combinatorial chemo-photothermal therapy of tumors(2018/12/27)

    作者:Cheng Zhang,Shibo Wang,Zhaoxia Chen

    期刊:Nanoscale

    DOI:10.1039/c8nr09064e

    影响因子 :8.307

    引用产品:CL-0007 CL-0071

  • A multimodal strategy of Fe3O4@ZIF-8/GOx@MnO2 hybrid nanozyme via TME modulation for tumor therapy(2021/09/15)

    作者:Yu Zhang, Yifeng Yang, Jinsheng Shi

    期刊:Nanoscale

    DOI:10.1039/d1nr04196g

    影响因子 :8.307

    引用产品:164210 164210-50 CL-0007

  • Micelle nanovehicles for co-delivery of Lepidium meyenii Walp. (maca) polysaccharide and chloroquine to tumor-associated macrophages for synergistic cancer immunotherapy(2021/08/25)

    作者:Ye Yang, Tingting Guo, Junwei Xu

    期刊:International Journal Of Biological Macromolecules

    DOI:10.1016/j.ijbiomac.2021.08.155

    影响因子 :8.025

    引用产品:CL-0007 CL-0190

  • UCPs/Zn2GeO4:Mn2+/g-C3N4 heterojunction engineered injectable thermosensitive hydrogel for oxygen independent breast cancer neoadjuvant photodynamic therapy(2021/01/13)

    作者:Linchao Zhang, Manli Yang, Yishun Ji

    期刊:Biomaterials Science

    DOI:10.1039/D0BM01876G

    影响因子 :7.590

    引用产品:CL-0007

  • Oxygen-rich chemotherapy via modified Abraxane to inhibit the growth and metastasis of triple-negative breast cancer(2018/11/13)

    作者:Lingtong Meng, Shaoju Gan, Ya Zhou

    期刊:Biomaterials Science

    DOI:10.1039/C8BM00753E

    影响因子 :7.590

    引用产品:CL-0007

  • Photosensitizer loaded PEG-MoS₂–Au hybrids for CT/NIRF imaging-guided stepwise photothermal and photodynamic therapy(2017/02/24)

    作者:Li Liu, Jinping Wang, Xiaoxiao Tan

    期刊:Journal of materials chemistry B

    DOI:10.1039/C6TB03352K

    影响因子 :7.571

    引用产品:CL-0007

  • NIRF/PA/CT multi-modality imaging guided combined photothermal and photodynamic therapy based on tumor microenvironment-responsive nanocomposites(2018/06/18)

    作者:Li Liu, Jinping Wang, Qing You

    期刊:Journal of Materials chemistry. B

    DOI:10.1039/c8tb00859k

    影响因子 :7.571

    引用产品:CL-0007

  • Magnetically-targeted and near infrared fluorescence/magnetic resonance/photoacoustic imaging-guided combinational anti-tumor phototherapy based on polydopamine-capped magnetic Prussian blue nanoparticles(2018/04/06)

    作者:Yidan Wang, Xiaojuan Pang, Jinping Wang

    期刊:Journal of Materials Chemistry B

    DOI:10.1039/C8TB00483H

    影响因子 :7.571

    引用产品:CL-0007

  • Synergistic Theranostics of Magnetic ResonanceImaging and Photothermal Therapy of Breast CancerBased on the Janus Nanostructures Fe3O4-Aushell-PEG(2021/09/16)

    作者:Xun Kang, Tao Sun, Liang Zhang

    期刊:International Journal of Nanomedicine

    DOI:10.2147/IJN.S322894

    影响因子 :7.0330

    引用产品:CL-0007

  • Persistent luminescence-polypyrrole nanocomposite for dual-modal imaging and photothermal therapy of mammary cancer(2020/07/18)

    作者:Shuqi Wu, Yang Li, Ruofei Zhang

    期刊:Talanta

    DOI:10.1016/j.talanta.2020.121435

    影响因子 :6.556

    引用产品:CL-0007 CL-0101

  • Free paclitaxel-loaded E-selectin binding peptide modified micelle self-assembled from hyaluronic acid-paclitaxel conjugate inhibit breast cancer metastasis in a murine model(2017/05/31)

    作者:Xiaofeng Han, Xuerong Dong, Jing Li

    期刊:International Journal Of Pharmaceutics

    DOI:10.1016/j.ijpharm.2017.05.063

    影响因子 :6.510

    引用产品:CL-0007

  • Interface-Engineered Paclitaxel-Based Hollow Mesoporous Organosilica Nanoplatforms for Photothermal-Enhanced Chemotherapy of Tumor(2021/11/05)

    作者:Chunxi Qian, Bandar Alhamyari, Xiaofei Tang

    期刊:Molecular Pharmaceutics

    DOI:10.1021/acs.molpharmaceut.1c00735

    影响因子 :5.3640

    引用产品:CL-0007

  • Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells(2020/8/19)

    作者:Azubuike Peter Ebokaiwe, Emmanuel Mfotie Njoya, Yuwen Sheng

    期刊:Toxicology And Applied Pharmacology

    DOI:10.1016/j.taap.2020.115203

    影响因子 :4.2190

    引用产品:CL-0007

  • Xiaoyao Kangai Jieyu Fang, a Chinese Herbal Formulation, Ameliorates Cancer-Related Depression Concurrent with Breast Cancer in Mice via Promoting Hippocampal Synaptic Plasticity(2018/11/18)

    作者:Pan Meng, Yuanshan Han, Qin Yang

    期刊:Evidence-Based Complementary and Alternative Medicine

    DOI:10.1155/2018/3967642

    影响因子 :2.650

    引用产品:CL-0007

  • Lidocaine prevents breast cancer growth by targeting neuronatin to inhibit nerve fibers formation(2021/7/1)

    作者:Bingda Li, Hao Xu, Chongwu He

    期刊:Journal Of Toxicological Sciences

    DOI:10.2131/jts.46.329

    影响因子 :1.7920

    引用产品:CL-0007 CL-0150A

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