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产品概述
名称 | 786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确) |
别称 | 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
生长培养基 | RPMI-1640+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | 786-O [786-0]细胞源自一个原发性透明细胞癌;786-O [786-0]细胞有微绒毛和桥粒,能在软琼脂内生长。786-O [786-0]细胞生成的一个PTH样的多肽与乳癌和肺癌中的肽相似。这个多肽的N端与PTH相似,活性与PTH相似,分子量为6000道尔顿。 |
年龄(性别) | 男;58岁 |
组织来源 | 肾;肾细胞腺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肾癌细胞 |
生物安全等级 | 1 |
倍增时间 | ~24-45 hours |
致瘤性 | Yes, in immunosuppressed hamsters. |
保藏机构 | ATCC; CRL-1932 BCRC; 60243 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10 D2S1338 17,18 D3S1358 16 D5S818 9 D7S820 11,12 D8S1179 13 D13S317 8 D16S539 12 D18S51 13,14 D19S433 14,15 D21S11 29,30 FGA 24 PentaD 9,12 PentaE 7,16 TH01 6,9.3 TPOX 8,11 vWA 15,17 D6S1043 11 D12S391 17,18 D2S441 10,11 -
STR鉴定图
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参考文献
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Tumor promoting effects of circRNA_001287 on renal cell carcinoma through miR-144-targeted CEP55(2020/12/01)
作者:Jiafu Feng, Yongcan Guo, Yuanmeng Li
期刊:Journal Of Experimental & Clinical Cancer Research
DOI:10.1186/s13046-020-01744-2
影响因子 :11.300
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YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway(2022/08/17)
作者:Wei Li, Kun Ye, Xurui Li
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-022-02460-9
影响因子 :11.300
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The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors(2022/04/02)
作者:Liu Wentao, Zhang Bin, Zhang Dan
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-04760-6
影响因子 :9.000
引用产品:CL-0005 CL-0010 CL-0021 PB180120 PM150110 PM150210 PM150410
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Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming(2023/02/20)
作者:Zhangnan Liu, Mengzhen Fan, Junqing Hou
期刊:Cell Death & Disease
DOI:10.1038/s41419-023-05677-4
影响因子 :9.000
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The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis(2023/02/02)
作者:Yapeng Wang, Mou Peng, Yawen Zhong
期刊:ONCOGENE
DOI:10.1038/s41388-023-02613-w
影响因子 :8.000
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Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis.(2022/09/21)
作者:Longfei Yang, Yuwei Zhang, Yang Wang
期刊:Frontiers in Pharmacology
影响因子 :5.600
引用产品:CL-0002 CL-0010 CL-0052 CL-0075 CL-0109 CL-0185 CL-0200 CL-0222 CL-0227 CM-H019 PM150110 PM150210 PM150910
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The mechanism of long-chain acyl-CoA synthetase 3 in inhibiting cell proliferation, migration, and invasion in clear cell renal cell carcinoma(2023/03/15)
作者:Lin Zhang, Bo Wu, Dongwen Wang
期刊:American Journal of Cancer Research
DOI:PMID:37034217
影响因子 :5.300
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Hypoxia-induced microRNA-155 overexpression in extracellular vesicles promotes renal cell carcinoma progression by targeting FOXO3(2021/03/19)
作者:Liwei Meng, Zhaoquan Xing, Zhaoxin Guo
期刊:Aging-US
影响因子 :5.200
引用产品:CL-0010
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Tumor-associated M2 macrophages in the immune microenvironment influence the progression of renal clear cell carcinoma by regulating M2 macrophage-associated genes(2023/06/08)
作者:Xiaoxu Zhang, Yang Sun, Yushuo Ma
期刊:Frontiers in Oncology
影响因子 :4.700
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A pan-cancer analysis of DDR1 in prognostic signature and tumor immunity, drug resistance(2023/04/08)
作者:Longfei Yang, Yuwei Zhang, Yifan Tang
期刊:Scientific Reports
DOI:10.1038/s41598-023-27975-9
影响因子 :4.600
引用产品:CL-0002 CL-0010 CL-0052 CL-0075 CL-0109 CL-0185 CL-0200 CL-0222 CL-0227 CM-H019 PM150110 PM150210 PM150910
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AKG induces cell apoptosis by inducing reactive oxygen species-mediated endoplasmic reticulum stress and by suppressing PI3K/AKT/mTOR-mediated autophagy in renal cell carcinoma(2022/09/16)
作者:Fan Wu, Xuexia Xie, Guoliang Li
期刊:ENVIRONMENTAL TOXICOLOGY
影响因子 :4.500
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma(2019/05/21)
作者:Jin Wang, Chao Tang, Chao Yang
期刊:J Cancer
影响因子 :4.478
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GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling(2023/01/20)
作者:Shujiang Ye, Siyu Li, Lei Qin
期刊:ONCOLOGY REPORTS
影响因子 :4.200
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δ‐Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β‐catenin nuclear localization and activating its downstream target genes(2020/01/28)
作者:Lincheng Ju, Liping Shan, Bo Yin
期刊:Cancer Medicine
影响因子 :4.000
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Total Flavone Content of Cydonia oblonga Miller Inhibits Proliferation and Migration of Renal Carcinoma Cells by Inhibiting the S1PR2/FAK Pathway(2023/03/30)
作者:Muhadaisi Nuer, Nawaz Khan, Bentuo Zhang
期刊:JOURNAL OF FOOD BIOCHEMISTRY
影响因子 :4.000
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The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi-omics study(2021/11/10)
作者:Fangshi Xu, Yibing Guan, Li Xue
期刊:Cancer Medicine
影响因子 :4.000
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma(2019/5/21)
作者:Jin Wang, Chao Tang, Chao Yang
期刊:Journal of Cancer
影响因子 :3.900
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HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma(2021/2/19)
作者:Yuanbo Cui, Chunyan Zhang, Ya Li
期刊:Cell Biology International
影响因子 :3.900
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Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma(2022/08/09)
作者:Xiao Liu, Meng Jiang, Chenggang Pang
期刊:BMC CANCER
DOI:10.1186/s12885-022-09965-8
影响因子 :3.800
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Comprehensive analysis of the HOXA gene family identifes HOXA13as a novel oncogenic gene in kidney renal clear cell carcinoma(2020/05/22)
作者:Yuanbo Cui, Ming Yan, Chunyan Zhang
期刊:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI:10.1007/s00432-020-03259-x
影响因子 :3.600
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway(2023/01/02)
作者:Zhechuan Zhang, Yuanfeng Zhang, Ronggui Zhang
期刊:MEDICAL ONCOLOGY
DOI:10.1007/s12032-022-01926-2
影响因子 :3.400
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Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma(2018/3/7)
作者:Chao Tang, Jin Wang, Qi Wei
期刊:Oncology Letters
影响因子 :2.900
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Silencing of circular RNA PUM1 inhibits clear cell renal cell carcinoma progression through the miR-340-5p/FABP7 axis(2021/1/20)
作者:Fanchang Zeng, Liumei Luo, Mi Song
期刊:Journal Of Receptors And Signal Transduction
DOI:10.1080/10799893.2020.1870494
影响因子 :2.800
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APOBEC1 complementation factor facilitates cell migration by promoting nucleus translocation of SMAD3 in renal cell carcinoma cells(2021/3/17)
作者:Hua Xia, Yamin Liu, Lei Xu
期刊:IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
DOI:10.1007/s11626-021-00589-z.
影响因子 :2.100
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Identification of a combined lncRNA prognostic signature and knockdown of lncRNA MANCR to inhibit progression of clear cell renal cell carcinoma by bioinformatics analysis(2022/09/01)
作者:Sheng Xue, Hanxu Guo, Shibo Wei
期刊:Translational Andrology and Urology
影响因子 :2.000
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Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression(2022/11/30)
作者:Liqing Yang, Lin Wang, Jitao Wu, Yongqiang Wang
期刊:TRANSPLANT IMMUNOLOGY
DOI:10.1016/j.trim.2022.101764
影响因子 :1.500