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![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0010-1-1.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0010-1-2.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0010-1-3.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0010-1-4.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0010-1-5.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0010-1-6.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/product/cell-line-new.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0010-1-1.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0010-1-2.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0010-1-3.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0010-1-4.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0010-1-5.jpg)
![786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0010-1-6.jpg)
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产品概述
| 名称 | 786-O [786-0] (人肾透明细胞腺癌细胞) (STR鉴定正确) |
| 别称 | 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 生长培养基 | RPMI-1640＋10% FBS＋1% P/S |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 背景描述 | 786-O [786-0]细胞源自一个原发性透明细胞癌；786-O [786-0]细胞有微绒毛和桥粒，能在软琼脂内生长。786-O [786-0]细胞生成的一个PTH样的多肽与乳癌和肺癌中的肽相似。这个多肽的N端与PTH相似，活性与PTH相似，分子量为6000道尔顿。 |
| 年龄（性别） | 男；58岁 |
| 组织来源 | 肾；肾细胞腺癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肾癌细胞 |
| 生物安全等级 | 1 |
| 倍增时间 | ~24-45 hours |
| 致瘤性 | Yes, in immunosuppressed hamsters. |
| 保藏机构 | ATCC; CRL-1932 BCRC; 60243 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10 D2S1338 17,18 D3S1358 16 D5S818 9 D7S820 11,12 D8S1179 13 D13S317 8 D16S539 12 D18S51 13,14 D19S433 14,15 D21S11 29,30 FGA 24 PentaD 9,12 PentaE 7,16 TH01 6,9.3 TPOX 8,11 vWA 15,17 D6S1043 11 D12S391 17,18 D2S441 10,11 -
STR鉴定图
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参考文献
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Tumor promoting effects of circRNA_001287 on renal cell carcinoma through miR-144-targeted CEP55(2020/12/01)
作者：Jiafu Feng, Yongcan Guo, Yuanmeng Li
期刊：Journal Of Experimental & Clinical Cancer Research
DOI：10.1186/s13046-020-01744-2
影响因子 ：11.300
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YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway(2022/08/17)
作者：Wei Li, Kun Ye, Xurui Li
期刊：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI：10.1186/s13046-022-02460-9
影响因子 ：11.300
-
The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors(2022/04/02)
作者：Liu Wentao, Zhang Bin, Zhang Dan
期刊：Cell Death & Disease
DOI：10.1038/s41419-022-04760-6
影响因子 ：9.000
引用产品：CL-0005 CL-0010 CL-0021 PB180120 PM150110 PM150210 PM150410
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Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming(2023/02/20)
作者：Zhangnan Liu, Mengzhen Fan, Junqing Hou
期刊：Cell Death & Disease
DOI：10.1038/s41419-023-05677-4
影响因子 ：9.000
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The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis(2023/02/02)
作者：Yapeng Wang, Mou Peng, Yawen Zhong
期刊：ONCOGENE
DOI：10.1038/s41388-023-02613-w
影响因子 ：8.000
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Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis.(2022/09/21)
作者：Longfei Yang, Yuwei Zhang, Yang Wang
期刊：Frontiers in Pharmacology
影响因子 ：5.600
引用产品：CL-0002 CL-0010 CL-0052 CL-0075 CL-0109 CL-0185 CL-0200 CL-0222 CL-0227 CM-H019 PM150110 PM150210 PM150910
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The mechanism of long-chain acyl-CoA synthetase 3 in inhibiting cell proliferation, migration, and invasion in clear cell renal cell carcinoma(2023/03/15)
作者：Lin Zhang, Bo Wu, Dongwen Wang
期刊：American Journal of Cancer Research
DOI：PMID:37034217
影响因子 ：5.300
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Hypoxia-induced microRNA-155 overexpression in extracellular vesicles promotes renal cell carcinoma progression by targeting FOXO3(2021/03/19)
作者：Liwei Meng, Zhaoquan Xing, Zhaoxin Guo
期刊：Aging-US
影响因子 ：5.200
引用产品：CL-0010
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Tumor-associated M2 macrophages in the immune microenvironment influence the progression of renal clear cell carcinoma by regulating M2 macrophage-associated genes(2023/06/08)
作者：Xiaoxu Zhang, Yang Sun, Yushuo Ma
期刊：Frontiers in Oncology
影响因子 ：4.700
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A pan-cancer analysis of DDR1 in prognostic signature and tumor immunity, drug resistance(2023/04/08)
作者：Longfei Yang, Yuwei Zhang, Yifan Tang
期刊：Scientific Reports
DOI：10.1038/s41598-023-27975-9
影响因子 ：4.600
引用产品：CL-0002 CL-0010 CL-0052 CL-0075 CL-0109 CL-0185 CL-0200 CL-0222 CL-0227 CM-H019 PM150110 PM150210 PM150910
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AKG induces cell apoptosis by inducing reactive oxygen species-mediated endoplasmic reticulum stress and by suppressing PI3K/AKT/mTOR-mediated autophagy in renal cell carcinoma(2022/09/16)
作者：Fan Wu, Xuexia Xie, Guoliang Li
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.500
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma(2019/05/21)
作者：Jin Wang, Chao Tang, Chao Yang
期刊：J Cancer
影响因子 ：4.478
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GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling(2023/01/20)
作者：Shujiang Ye, Siyu Li, Lei Qin
期刊：ONCOLOGY REPORTS
影响因子 ：4.200
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δ‐Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β‐catenin nuclear localization and activating its downstream target genes(2020/01/28)
作者：Lincheng Ju, Liping Shan, Bo Yin
期刊：Cancer Medicine
影响因子 ：4.000
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Total Flavone Content of Cydonia oblonga Miller Inhibits Proliferation and Migration of Renal Carcinoma Cells by Inhibiting the S1PR2/FAK Pathway(2023/03/30)
作者：Muhadaisi Nuer, Nawaz Khan, Bentuo Zhang
期刊：JOURNAL OF FOOD BIOCHEMISTRY
影响因子 ：4.000
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The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi-omics study(2021/11/10)
作者：Fangshi Xu, Yibing Guan, Li Xue
期刊：Cancer Medicine
影响因子 ：4.000
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma(2019/5/21)
作者：Jin Wang, Chao Tang, Chao Yang
期刊：Journal of Cancer
影响因子 ：3.900
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HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma(2021/2/19)
作者：Yuanbo Cui, Chunyan Zhang, Ya Li
期刊：Cell Biology International
影响因子 ：3.900
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Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma(2022/08/09)
作者：Xiao Liu, Meng Jiang, Chenggang Pang
期刊：BMC CANCER
DOI：10.1186/s12885-022-09965-8
影响因子 ：3.800
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Comprehensive analysis of the HOXA gene family identifes HOXA13as a novel oncogenic gene in kidney renal clear cell carcinoma(2020/05/22)
作者：Yuanbo Cui, Ming Yan, Chunyan Zhang
期刊：JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
DOI：10.1007/s00432-020-03259-x
影响因子 ：3.600
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway(2023/01/02)
作者：Zhechuan Zhang, Yuanfeng Zhang, Ronggui Zhang
期刊：MEDICAL ONCOLOGY
DOI：10.1007/s12032-022-01926-2
影响因子 ：3.400
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Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma(2018/3/7)
作者：Chao Tang, Jin Wang, Qi Wei
期刊：Oncology Letters
影响因子 ：2.900
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Silencing of circular RNA PUM1 inhibits clear cell renal cell carcinoma progression through the miR-340-5p/FABP7 axis(2021/1/20)
作者：Fanchang Zeng, Liumei Luo, Mi Song
期刊：Journal Of Receptors And Signal Transduction
DOI：10.1080/10799893.2020.1870494
影响因子 ：2.800
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APOBEC1 complementation factor facilitates cell migration by promoting nucleus translocation of SMAD3 in renal cell carcinoma cells(2021/3/17)
作者：Hua Xia, Yamin Liu, Lei Xu
期刊：IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
DOI：10.1007/s11626-021-00589-z.
影响因子 ：2.100
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Identification of a combined lncRNA prognostic signature and knockdown of lncRNA MANCR to inhibit progression of clear cell renal cell carcinoma by bioinformatics analysis(2022/09/01)
作者：Sheng Xue, Hanxu Guo, Shibo Wei
期刊：Translational Andrology and Urology
影响因子 ：2.000
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Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression(2022/11/30)
作者：Liqing Yang, Lin Wang, Jitao Wu, Yongqiang Wang
期刊：TRANSPLANT IMMUNOLOGY
DOI：10.1016/j.trim.2022.101764
影响因子 ：1.500
