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产品概述
| 名称 | A172 (人胶质母细胞瘤细胞) (STR鉴定正确) |
| 别称 | A172; A 172; A-172 MG; A-172MG |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 成纤维细胞样 |
| 生长培养基 | DMEM＋10% FBS＋1% P/S |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 背景描述 | A172细胞在半固体培养基中可形成克隆；A172细胞在免疫抑制小鼠中不成瘤。 |
| 年龄（性别） | 男；53岁 |
| 组织来源 | 脑；胶质母细胞瘤 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胶质瘤细胞 |
| 生物安全等级 | 1 |
| 倍增时间 | ~40 hours |
| 致瘤性 | No, the cells were not tumorigenic in immunosuppressed mice.Yes, form colonies in semisolid medium. |
| 保藏机构 | ATCC; CRL-1620 ATCC; CRL-7899ECACC; 88062428 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 9,12 D2S1338 20,21 D3S1358 14,18 D5S818 11,12 D7S820 11 D8S1179 13,14 D13S317 11 D16S539 12 D18S51 12,13 D19S433 12,15.2 D21S11 28,32.2 FGA 20,22 PentaD 9,13 PentaE 5,10 TH01 6,9.3 TPOX 8,11 vWA 20 D6S1043 13,18 D12S391 22 D2S441 10,11 -
STR鉴定图
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参考文献
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Chitinase-3 like-protein-1 promotes glioma progression via the NF-κB signaling pathway and tumor microenvironment reprogramming.(2022/10/03)
作者：Ting Zhao, Jianming Zeng, Yujie Xu
期刊：Theranostics
影响因子 ：12.400
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Overexpression of GINS4 is associated with poor prognosis and survival in glioma patients(2021/09/23)
作者：Binfeng Liu, Zhendong Liu, Yanbiao Wang
期刊：Molecular Medicine
DOI：10.1186/s10020-021-00378-0
影响因子 ：5.700
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Overexpressed XRCC2 as an independent risk factor for poor prognosis in glioma patients(2021/05/29)
作者：Zhendong Liu, Wang Zhang, Xingbo Cheng
期刊：Molecular Medicine
DOI：10.1186/s10020-021-00316-0
影响因子 ：5.700
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Nifuroxazide inhibits the growth of glioblastoma and promotes the infiltration of CD8 T cells to enhance antitumour immunity(2023/03/14)
作者：Xinzhuang Wang, Junyi Ye, Ming Gao
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.109987
影响因子 ：5.600
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RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12(2022/11/15)
作者：Liang Liu, Xuelan Zhou, Shan Cheng, Yuyuan Ge, Baomin Chen, Jia Shi, Haoran Li, Suwen Li, Yongdong Li, Jiaqi Yuan, Anyi Wu, Xinglei Liu, Shilu Huang, Zhipeng Xu, Jun Dong
期刊：CNS Neuroscience & Therapeutics
影响因子 ：5.500
引用产品：CL-0012 CL-0233 CL-0237 CL-0458 CL-0578 CL-0583 CP-H122
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ITGB3BP is a potential biomarker associated with poor prognosis of glioma( 2021/12/24)
作者：Zhendong Liu, Binfeng Liu, Lu Bian
期刊：Journal of Cellular and Molecular Medicine
影响因子 ：5.300
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Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway(2023/06/02)
作者：Lei Zhang, Peng Luo, Xinggang Mao
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
DOI：10.1016/j.bbamcr.2023.119509
影响因子 ：5.100
引用产品：164210-50 CL-0012 CL-0237 CL-0238 CL-0458 CL-0583 PB180120 PM150210 PM150410
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GD2 CAR-T cells in combination with Nivolumab exhibit enhanced antitumor efficacy(2023/03/24)
作者：Guangji Zhang, Yu Zhao, Zhongfeng Liu
期刊：Translational Oncology
DOI：10.1016/j.tranon.2023.101663
影响因子 ：5.000
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CKAP4-mediated activation of FOXM1 via phosphorylation pathways regulates malignant behavior of glioblastoma cells(2023/01/24)
作者：Kaiyue Xu, Kaiqian Zhang, Jiying Ma
期刊：Translational Oncology
DOI：10.1016/j.tranon.2023.101628
影响因子 ：5.000
引用产品：CL-0012
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Sevoflurane inhibits progression of glioma via regulating the HMMR antisense RNA 1/microRNA-7/cyclin dependent kinase 4 axis(2021/8/31)
作者：Xian Bao, Yibo Peng, Jun Shen
期刊：Bioengineered
DOI：10.1080/21655979.2021.1976712
影响因子 ：4.900
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β3GNT9 as a prognostic biomarker in glioblastoma and its association with glioblastoma immune infiltration, migration and invasion(2023/09/12)
作者：YingHao Luo, Kan Wang, Lu Zhan
期刊：Frontiers in Oncology
影响因子 ：4.700
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Prognostic Significance of mRNA Expression RBBP8 or Its Methylation in Gliomas(2022/02/01)
作者：Zhendong Liu, Xingbo Cheng, Shaochong Lin
期刊：Cellular And Molecular Neurobiology
DOI：10.1007/s10571-022-01198-4
影响因子 ：4.231
引用产品：CL-0012
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Inhibition of FAM83D displays antitumor effects in glioblastoma via down-regulation of the AKT/Wnt/β-catenin pathway(2022/02/12)
作者：Jubo Wang, Yu Quan, Jian Lv
期刊：Environmental Toxicology
影响因子 ：4.109
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CircRNA circ_POSTN promotes the malignancy of glioma by regulating the miR-433-3p/SPARC axis(2022/12/01)
作者：Xiangting Hua, Chaoyong Zhang, Yongfeng Ba
期刊：METABOLIC BRAIN DISEASE
DOI：10.1007/s11011-022-01126-x
影响因子 ：3.600
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EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR(2022/01/17)
作者：Xiaoli Li, Chengmou Wang, Guanghui Chen
期刊： Metabolic Brain Disease
DOI：10.1007/s11011-021-00899-x
影响因子 ：3.600
引用产品：164210 CL-0012 CL-0237 CL-0238 CL-0583 PB180120 PM150210
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Circular RNA circ_0000741/miR-379-5p/TRIM14 signaling axis promotes HDAC inhibitor (SAHA) tolerance in glioblastoma(2023/03/11)
作者：Liang Meng, Yuefei Wang, Qin Tu
期刊：METABOLIC BRAIN DISEASE
DOI：10.1007/s11011-023-01184-9
影响因子 ：3.600
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EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR(2022/01/17)
作者：Xiaoli Li, Chengmou Wang, Guanghui Chen
期刊： Metabolic Brain Disease
DOI：10.1007/s11011-021-00899-x
影响因子 ：3.600
引用产品：164210 CL-0012 CL-0237 CL-0238 CL-0583 PB180120 PM150210
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Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma(2022/10/27)
作者：Xuzhao Li, Nianhua Wang, Haibin Leng
期刊：METABOLIC BRAIN DISEASE
DOI：10.1007/s11011-022-01069-3
影响因子 ：3.600
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Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway(2021/7/23)
作者：Dekang Wang, Aili Hu, Hao Peng
期刊：3 BIOTECH
DOI：10.1007/s13205-021-02922-5
影响因子 ：2.800
