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产品概述
| 名称 | THP-1 (人单核细胞白血病) (STR鉴定正确) |
| 别称 | THP1; THP 1; THPI; THP-1(ATCC); Tohoku Hospital Pediatrics-1 |
| 种属 | 人 |
| 生长特性 | 悬浮细胞 |
| 细胞形态 | 单核细胞 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 5×10^5-1×10^6cells/mL |
| 推荐换液频率 | 2-3次/周 |
| 注意事项 | 该细胞为悬浮细胞，请注意离心收集细胞悬液；请勿直接倒掉细胞培养液。 |
| 背景描述 | THP-1细胞对乳汁珠和激活的红细胞有吞噬作用，无表面和胞质免疫球蛋白。THP-1细胞可以用佛波醇、TPA诱导单核细胞分化。 |
| 年龄（性别） | 男性；1岁 |
| 组织来源 | 急性单核细胞白血病，单核细胞 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 白血病细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~36-72 hours |
| 受体表达情况 | complement (C3), expressed;Fc, expressed |
| 抗原表达情况 | HLA A2, A9, B5, DRw1, DRw2 |
| 基因表达情况 | lysozyme, HLA A2, A9, B5, DRw1, DRw2 |
| 保藏机构 | ATCC; TIB-202 DSMZ; ACC-16 ECACC; 88081201 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 11,13 D2S1338 17,18 D3S1358 15,17 D5S818 11,12 D7S820 10 D8S1179 10,14 D13S317 13 D16S539 11,12 D18S51 13,14 D19S433 12.2,13 D21S11 30,31.2 FGA 24,25 PentaD 10,12 PentaE 11,15 TH01 8,9.3 TPOX 8,11 vWA 16 D6S1043 14 D12S391 19 D2S441 10,11 -
STR鉴定图
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参考文献
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NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice(2023/08/09)
作者：Cheng Cheng, Jie Zhang, Xiaodong Li
期刊：Signal Transduction and Targeted Therapy
DOI：10.1038/s41392-023-01560-y
影响因子 ：39.300
引用产品：CL-0233
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Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles(2022/08/23)
作者：YangLin Wu, Chenhui Zhang, Yun Teng
期刊：Military Medical Research
DOI：10.1186/s40779-022-00404-0
影响因子 ：21.200
-
Serum/glucocorticoid-inducible kinase 1 deficiency induces NLRP3 inflammasome activation and autoinflammation of macrophages in a murine endolymphatic hydrops model(2023/03/06)
作者：Daogong Zhang, Wenqian Yu, Jiahui Liu
期刊：Nature Communications
DOI：10.1038/s41467-023-36949-4
影响因子 ：16.600
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Single-cell analysis of peripheral blood from high-altitude pulmonary hypertension patients identifies a distinct monocyte phenotype(2023/03/31)
作者：Xinhua Wu, Yangyang He, Zhangrong Chen
期刊：Nature Communications
DOI：10.1038/s41467-023-37527-4
影响因子 ：16.600
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Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury(2024/01/01)
作者：Shanshan Liu, Xinyu Xiao, La Zhang
期刊：Theranostics
影响因子 ：12.400
引用产品：CL-0233
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Water-extracted Lonicera japonica polysaccharide attenuates allergic rhinitis by regulating NLRP3-IL-17 signaling axis(2022/09/03)
作者：Xinyu Bai, Ping Liu, Hengyan Shen
期刊：CARBOHYDRATE POLYMERS
DOI：10.1016/j.carbpol.2022.120053
影响因子 ：11.200
-
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer(2022/12/10)
作者：Xiaoyan Yang, Jinguo Zhang, Qiaomei Zhou
期刊：JOURNAL OF NANOBIOTECHNOLOGY
DOI：10.1186/s12951-022-01738-6
影响因子 ：10.200
-
The ketone body β-hydroxybutyrate alleviates CoCrMo alloy particles induced osteolysis by regulating NLRP3 inflammasome and osteoclast differentiation(2022/03/09)
作者：Yanglin Wu,Yun Teng, Chenhui Zhang
期刊：Journal Of Nanobiotechnology
DOI：10.1186/s12951-022-01320-0
影响因子 ：10.200
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Enhanced Anticoagulation of Hierarchy Liquid Infused Surfaces in Blood Flow(2023/11/17)
作者：Shuguang Zhang, Yuhe Wang, Kuilin Meng
期刊：ACS Applied Materials & Interfaces
影响因子 ：9.500
引用产品：CL-0233
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HIMF deletion ameliorates acute myocardial ischemic injury by promoting macrophage transformation to reparative subtype(2021/04/23)
作者：Yanjiao Li, Min Dong, Qing Wang
期刊：Basic Research in Cardiology
DOI：10.1007/s00395-021-00867-7
影响因子 ：9.500
引用产品：CL-0233
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SLC1A5 enhances malignant phenotypes through modulating ferroptosis status and immune microenvironment in glioma(2022/12/24)
作者：Liying Han, Jinpeng Zhou, Leiyang Li
期刊：Cell Death & Disease
DOI：10.1038/s41419-022-05526-w
影响因子 ：9.000
-
Sequentially suspended 3D bioprinting of multiple-layered vascular models with tunable geometries for in vitro modeling of arterial disorders initiation(2023/08/14)
作者：Chen Pan, Jingwen Xu, Qiqi Gao
期刊：Biofabrication
影响因子 ：9.000
引用产品：CL-0233
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Exosomal transfer of tumor-associated macrophage-derived hsa_circ_0001610 reduces radiosensitivity in endometrial cancer(2021/08/30)
作者：Xiaobin Gu, Yonggang Shi, Meilian Dong
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-04087-8
影响因子 ：9.000
-
DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation(2021/09/21)
作者：Tanjing Song, Qingli Zou, Yingying Yan
期刊：Cell Reports
DOI：10.1016/j.celrep.2021.109739
影响因子 ：8.800
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Fucoidan-loaded, neutrophil membrane-coated nanoparticles facilitate MRSA-accompanied wound healing(2023/02/18)
作者：Jingyi Li, Jiahao Wang, Zhen Zhang
期刊：MATERIALS & DESIGN
DOI：10.1016/j.matdes.2023.111758
影响因子 ：8.400
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Endothelial cell-derived MMP19 promotes pulmonary fibrosis by inducing E(nd)MT and monocyte infiltration(2023/03/13)
作者：Weiming Zhao, Lan Wang, Juntang Yang
期刊：Cell Communication and Signaling
DOI：10.1186/s12964-023-01040-4
影响因子 ：8.400
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Linc00657 promoted pyroptosis in THP-1-derived macrophages and exacerbated atherosclerosis via the miR-106b-5p/TXNIP/NLRP3 axis(2023/09/20)
作者：Yin Liang, Xiaodan Xu, Xi Xu
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2023.126953
影响因子 ：8.200
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Extracellular Vesicles from Akkermansia muciniphila Elicit Antitumor Immunity Against Prostate Cancer via Modulation of CD8+ T Cells and Macrophages(2021/04/20)
作者：Zhongwei Luo, Kun Xia, Yiwei Liu
期刊：International Journal of Nanomedicine
影响因子 ：8.000
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M2 Macrophage-Derived Exosomal lncRNA MIR4435-2HG Promotes Progression of Infantile Hemangiomas by Targeting HNRNPA1(2023/10/19)
作者：Zhiyu Li, Zhongying Cao, Nanxi Li
期刊：International Journal of Nanomedicine
影响因子 ：8.000
引用产品：CL-0233
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MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses(2022/03/12)
作者： JiajieTu, Yilong Fang, Dafei Han
期刊：Oncogene
DOI：10.1038/s41388-022-02236-7
影响因子 ：8.000
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Human Keratinocyte-Derived Exosomal MALAT1 Promotes Diabetic Wound Healing by Upregulating MFGE8 via microRNA-1914-3p(2023/02/20)
作者：Liwen Kuang, Chenchen Zhang, Binghui Li
期刊：International Journal of Nanomedicine
影响因子 ：8.000
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Autophagy inhibition and ferroptosis activation during atherosclerosis: Hypoxia-inducible factor 1α inhibitor PX-478 alleviates atherosclerosis by inducing autophagy and suppressing ferroptosis in macrophages(2023/03/21)
作者：Guofu Hu, Zihui Yuan, Jian Wang
期刊：BIOMEDICINE & PHARMACOTHERAPY
DOI：10.1016/j.biopha.2023.114333
影响因子 ：7.500
引用产品：CL-0233
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Trophoblast-derived miR-410-5p induces M2 macrophage polarization and mediates immunotolerance at the fetal-maternal interface by targeting the STAT1 signaling pathway(2024/01/04)
作者：Jing Yang, Longfei Li, Linlin Wang
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04831-y
影响因子 ：7.400
引用产品：CL-0233
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The application of HER2 and CD47 CAR-macrophage in ovarian cancer(2023/09/22)
作者：Yizhao Chen, Xiangling Zhu, Hanze Liu
期刊：Journal of Translational Medicine
DOI：10.1186/s12967-023-04479-8
影响因子 ：7.400
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AFM negatively regulates the infiltration of monocytes to mediate sepsis-associated acute kidney injury(2023/01/30)
作者：Caiyun Guo, Youling Fan, Jiurong Cheng
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2023.1049536
影响因子 ：7.300
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Prediction of prognosis, immunogenicity and efficacy of immunotherapy based on glutamine metabolism in lung adenocarcinoma(2022/08/11)
作者：Jichang Liu, Hongchang Shen, Wenchao Gu
期刊：Frontiers in Immunology
影响因子 ：7.300
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Design, Synthesis, and Biological Evaluation of Proteolysis-Targeting Chimeras as Highly Selective and Efficient Degraders of Extracellular Signal-Regulated Kinase 5(2023/09/26)
作者：Pengming Pan, Tongtong Geng, Zhongtang Li
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c00864
影响因子 ：7.300
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Synthesis and pharmacological validation of fluorescent diarylsulfonylurea analogues as NLRP3 inhibitors and imaging probes(2022/04/04)
作者：Jiannan Zhao, Yongling Li, Jing Ma, Jingting Liu
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2022.114338
影响因子 ：6.700
引用产品：CL-0233
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Melatonin alleviates pyroptosis by regulating the SIRT3/FOXO3α/ROS axis and interacting with apoptosis in Atherosclerosis progression(2023/12/02)
作者：Lin Cong, Xiankun Liu, Yiming Bai
期刊：BIOLOGICAL RESEARCH
DOI：10.1186/s40659-023-00479-6
影响因子 ：6.700
引用产品：CL-0233
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C/EBPβ is a key transcription factor of ox-LDL inducing THP-1 cells to release multiple pro-inflammatory cytokines(2021/10/04)
作者：Jun Ma, Xiangyu Yang, Xiaoping Chen
期刊：Inflammation Research
DOI：10.1007/s00011-021-01509-3
影响因子 ：6.700
引用产品：CL-0233
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Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis(2023/01/23)
作者：Jun Yang, Minxiu Wang, Yulan Xu
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2023.115144
影响因子 ：6.700
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RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma(2023/12/22)
作者：Shuai He, Ming Lu, Liang Zhang
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI：10.1016/j.bbadis.2023.166996
影响因子 ：6.200
引用产品：CL-0233
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WTAP promotes macrophage recruitment and increases VEGF secretion via N6-methyladenosine modification in corneal neovascularization(2023/04/03)
作者：Yanhui Bai, Xiaohang Jiao, Jinge Hu
期刊：BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
DOI：10.1016/j.bbadis.2023.166708
影响因子 ：6.200
引用产品：CL-0233
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Development of a novel HER2-CAR monocyte cell therapy with controllable proliferation and enhanced anti-tumor efficacy(2024/01/19)
作者：Bing Yang, Xiaoxue Wang, Xundong Wei
期刊：CHINESE MEDICAL JOURNAL
DOI：10.1097/CM9.0000000000002944
影响因子 ：6.100
引用产品：CL-0233
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Sennoside A is a novel inhibitor targeting caspase-1(2022/09/01)
作者：Jiasi Wu, Yuejia Lan, Xiaoke Shi
期刊：Food & Function
影响因子 ：6.100
-
SQSTM1/p62 Knockout by Using the CRISPR/Cas9 System Inhibits Migration and Invasion of Hepatocellular Carcinoma(2023/04/25)
作者：Jinghua Lu, Yipei Ding, Wanqiu Zhang
期刊：Cells
影响因子 ：6.000
引用产品：CL-0233
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Single-cell transcriptome analysis reveals aberrant stromal cells and heterogeneous endothelial cells in alcohol-induced osteonecrosis of the femoral head(2022/04/06)
作者：Liao Zheting, Jin Yu, Chu Yuhao
期刊：Communications Biology
DOI：10.1038/s42003-022-03271-6
影响因子 ：5.900
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1,25(OH)2D3 Promotes Macrophage Efferocytosis Partly by Upregulating ASAP2 Transcription via the VDR-Bound Enhancer Region and ASAP2 May Affect Antiviral Immunity(2022/11/21)
作者：Hui Shi, Jiangling Duan, Jiayu Wang, Haohao Li, Zhiheng Wu, Shuaideng Wang, Xueyan Wu, Ming Lu
期刊：Nutrients
影响因子 ：5.900
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Lactate from glycolysis regulates inflammatory macrophage polarization in breast cancer(2023/02/02)
作者：Chao Wang, Linxuan Xue, Wenqiang Zhu
期刊：CANCER IMMUNOLOGY IMMUNOTHERAPY
DOI：10.1007/s00262-023-03382-x
影响因子 ：5.800
引用产品：CL-0233
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Oncogenic FLT3 internal tandem duplication activates E2F1 to regulate purine metabolism in acute myeloid leukaemia(2023/02/17)
作者：Ziyao Ou, Ke Wang, Wenwen Shen
期刊：BIOCHEMICAL PHARMACOLOGY
影响因子 ：5.800
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Lack of NPR1 Increases Vascular Endothelial Adhesion through Induction of Integrin Beta 4(2022/10/20)
作者：Hongfei Liu, Jiankun Liu, Changkun Long
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
引用产品：CL-0233
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Integrating RNA-seq and scRNA-seq to explore the mechanism of macrophage ferroptosis associated with COPD.(2023/03/10)
作者：Pengbei Fan, Yige Zhang, Shenao Ding
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2023.1139137
影响因子 ：5.600
引用产品：CL-0233
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Glycolytic reprogramming controls periodontitis-associated macrophage pyroptosis via AMPK/SIRT1/NF-κB signaling pathway(2023/04/15)
作者：Yani He, Yuting Wang, Xiangbin Jia
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110192
影响因子 ：5.600
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Inhibiting vascular smooth muscle cell proliferation mediated by osteopontin via regulating gut microbial lipopolysaccharide: A novel mechanism for paeonol in atherosclerosis treatment(2022/08/11)
作者：Xiaoyan Shi, Hongfei Wu, Yarong Liu
期刊：Frontiers in Pharmacology
影响因子 ：5.600
引用产品：CL-0233
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Hepatocellular Carcinoma Cell-Derived Exosomal miR-21-5p Induces Macrophage M2 Polarization by Targeting RhoB(2023/02/27)
作者：Haiyang Yu, Jing Pan, Siyue Zheng
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
引用产品：CL-0233
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iNOS inhibitor S-methylisothiourea alleviates smoke inhalation-induced acute lung injury by suppressing inflammation and macrophage infiltration(2023/11/20)
作者：Yinghan Shi, Yan Cao, Xinjie Han
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.111097
影响因子 ：5.600
引用产品：CL-0233
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L-cystathionine protects against oxidative stress and DNA damage induced by oxidized low-density lipoprotein in THP-1-derived macrophages(2023/07/25)
作者：Hanlin Peng, Mingzhu Zhu, Wei Kong
期刊：Frontiers in Pharmacology
DOI：10.3389/fphar.2023.1161542
影响因子 ：5.600
引用产品：CL-0233
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ERp29 Attenuates Nicotine-Induced Endoplasmic Reticulum Stress and Inhibits Choroidal Neovascularization(2023/10/24)
作者：Tu Lu, Fangfang Xie, Chuangxin Huang
期刊：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 ：5.600
引用产品：CL-0233
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Ginsenoside Rg3 Alleviates ox-LDL Induced Endothelial Dysfunction and Prevents Atherosclerosis in ApoE−/− Mice by Regulating PPARγ/FAK Signaling Pathway(2020/04/22)
作者：Jianan Geng, Wenwen Fu, Xiaofeng Yu
期刊：Frontiers in Pharmacology
影响因子 ：5.600
引用产品：CL-0233
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Systematic analysis of lysine crotonylation in human macrophages responding to MRSA infection(2023/02/08)
作者：Hao Zhang, Wei Ma, Haoru Liu
期刊：Frontiers in Cellular and Infection Microbiology
DOI：10.3389/fcimb.2023.1126350
影响因子 ：5.500
引用产品：CL-0233
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RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12(2022/11/15)
作者：Liang Liu, Xuelan Zhou, Shan Cheng, Yuyuan Ge, Baomin Chen, Jia Shi, Haoran Li, Suwen Li, Yongdong Li, Jiaqi Yuan, Anyi Wu, Xinglei Liu, Shilu Huang, Zhipeng Xu, Jun Dong
期刊：CNS Neuroscience & Therapeutics
影响因子 ：5.500
引用产品：CL-0012 CL-0233 CL-0237 CL-0458 CL-0578 CL-0583 CP-H122
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Network pharmacology combines machine learning, molecular simulation dynamics and experimental validation to explore the mechanism of acetylbinankadsurin a in the treatment of liver fibrosis(2023/12/31)
作者：Wangxia Peng, Yupei Yang, Huaguan Lu
期刊：JOURNAL OF ETHNOPHARMACOLOGY
影响因子 ：5.400
引用产品：CL-0233
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Advanced glycation end products reduce macrophage‐mediated killing of Staphylococcus aureus by ARL8 upregulation and inhibition of autolysosome formation(2020/07/15)
作者：Xiaoying Xie, Chuan Yang, Chaohui Duan
期刊：European Journal Of Immunology
影响因子 ：5.400
引用产品：CL-0233
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Neuropeptide Y regulates cholesterol uptake and efflux in macrophages and promotes foam cell formation(2022/09/29)
作者：Yu Cai, Zhengchao Wang, Lun Li
期刊：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
影响因子 ：5.300
引用产品：CL-0233
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Negative feedback loop of ERK/CREB/miR‐212‐3p inhibits HBeAg‐induced macrophage activation(2020/08/07)
作者：Wenjun Chen, Hongjun Bian, Xiaoyu Xie
期刊：Journal Of Cellular And Molecular Medicine
影响因子 ：5.300
引用产品：CL-0233
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miR‐129‐2‐3p directly targets SYK gene and associates with the risk of ischaemic stroke in a Chinese population(2018/11/29)
作者：Suli Huang, Ziquan Lv, Ying Wen
期刊：Journal Of Cellular And Molecular Medicine
影响因子 ：5.300
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Sirt4 deficiency promotes the development of atherosclerosis by activating the NF-κB/IκB/CXCL2/3 pathway(2023/04/21)
作者：Shuting Chang, Guanzhao Zhang, Lanlan Li
期刊：ATHEROSCLEROSIS
DOI：10.1016/j.atherosclerosis.2023.04.006
影响因子 ：5.300
引用产品：CL-0233
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M-CSF secreted by gastric cancer cells exacerbates the progression of gastric cancer by increasing the expression of SHP2 in tumor-associated macrophages(2023/12/29)
作者：Shaohua Zhang, Dongfei Ren, Huiyu Hou
期刊：Aging-US
影响因子 ：5.200
引用产品：CL-0233
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Lnc_000048 Promotes Histone H3K4 Methylation of MAP2K2 to Reduce Plaque Stability by Recruiting KDM1A in Carotid Atherosclerosis(2023/01/23)
作者：Shuai Zhang, Yu Sun, Qi Xiao
期刊：MOLECULAR NEUROBIOLOGY
DOI：10.1007/s12035-023-03214-0
影响因子 ：5.100
引用产品：CL-0233
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ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury(2022/03/10)
作者：Zhen Yu, Xiaoyu Xie, Xiaonan Su
期刊：Cellular Signalling
DOI：10.1016/j.cellsig.2022.110304
影响因子 ：4.800
引用产品：CL-0233
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LncRNA-HOXC-AS2 regulates tumor-associated macrophage polarization through the STAT1/SOCS1 and STAT1/CIITA pathways to promote the progression of non-small cell lung cancer(2023/12/31)
作者：Cunli Yin, Jing Li, Siru Li
期刊：CELLULAR SIGNALLING
DOI：10.1016/j.cellsig.2023.111031
影响因子 ：4.800
引用产品：CL-0233
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α-Mangostin Inhibited M1 Polarization of Macrophages/Monocytes in Antigen-Induced Arthritis Mice by Up-Regulating Silent Information Regulator 1 and Peroxisome Proliferators-Activated Receptor γ Simultaneously(2023/02/22)
作者：Yijin Wu, Sasa Zhang, Qin Yin
期刊：Drug Design Development and Therapy
影响因子 ：4.800
引用产品：CL-0233
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An Autophagy-Associated MITF–GAS5–miR-23 Loop Attenuates Vascular Oxidative and Inflammatory Damage in Sepsis(2023/06/24)
作者：Junning Cheng, Chang Ding, Huying Tang
期刊：Biomedicines
DOI：10.3390/biomedicines11071811
影响因子 ：4.700
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Tumor-associated M2 macrophages in the immune microenvironment influence the progression of renal clear cell carcinoma by regulating M2 macrophage-associated genes(2023/06/08)
作者：Xiaoxu Zhang, Yang Sun, Yushuo Ma
期刊：Frontiers in Oncology
影响因子 ：4.700
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A comprehensive analysis of the role of QPRT in breast cancer(2023/09/18)
作者：Yiqing Yan, Lun Li, Zixin Wang
期刊：Scientific Reports
DOI：10.1038/s41598-023-42566-4
影响因子 ：4.600
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Betulinic Acid Attenuates Osteoarthritis via Limiting NLRP3 Inflammasome Activation to Decrease Interleukin-1β Maturation and Secretion(2023/09/25)
作者：Bo Liu, Yanglin Wu, Ting Liang
期刊：MEDIATORS OF INFLAMMATION
影响因子 ：4.600
引用产品：CL-0233
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Penfluroidol Attenuates the Imbalance of the Inflammatory Response by Repressing the Activation of the NLRP3 Inflammasome and Reduces Oxidative Stress via the Nrf2/HO-1 Signaling Pathway in LPS-Induced Macrophages(2023/08/22)
作者：Qiulin Li, Lidong Wu, Bin Cheng
期刊：MEDIATORS OF INFLAMMATION
影响因子 ：4.600
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CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway(2023/08/25)
作者：Haizhou Ji, Li Chen, Mi Ren
期刊：Pharmaceuticals
影响因子 ：4.600
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Hyaluronic Acid Oligosaccharide Derivatives Alleviate Lipopolysaccharide-Induced Inflammation in ATDC5 Cells by Multiple Mechanisms(2022/08/31)
作者：Hesuyuan Huang, Xuyang Ding, Dan Xing
期刊：MOLECULES
影响因子 ：4.600
引用产品：CL-0233
-
lncRNA IL-17RA-1 Attenuates LPS-Induced Sepsis via miR-7847-3p/PRKCG-Mediated MAPK Signaling Pathway(2022/10/13)
作者：Yuanxiu Gan, Jie Long, Yan Zeng
期刊：MEDIATORS OF INFLAMMATION
影响因子 ：4.600
引用产品：CL-0233
-
Quantitative Proteomic Analysis Reveals the Mechanisms of Sinapine Alleviate Macrophage Foaming(2023/02/21)
作者：Aiyang Liu, Bin Liao, Shipeng Yin
期刊：MOLECULES
影响因子 ：4.600
引用产品：CL-0233
-
Electroacupuncture Alleviates Lung Injury in CpG1826-Challenged Mice via Modulating CD39-NLRP3 Pathway(2023/08/02)
作者：Jiasi Wu, Xin Xiong, Xiumin Hu
期刊：Journal of Inflammation Research
影响因子 ：4.500
引用产品：CL-0233
-
M1-Type Macrophages Secrete TNF-α to Stimulate Vascular Calcification by Upregulating CA1 and CA2 Expression in VSMCs(2023/07/19)
作者：Xianqin Song, Yu Song, Quanping Ma
期刊：Journal of Inflammation Research
影响因子 ：4.500
-
Increased blood CD226- inflammatory monocytes with low antigen presenting potential correlate positively with severity of hemorrhagic fever with renal syndrome(2023/08/16)
作者：Kang Tang, Yongli Hou, Linfeng Cheng
期刊：ANNALS OF MEDICINE
DOI：10.1080/07853890.2023.2247000
影响因子 ：4.400
引用产品：CL-0233
-
Extracellular vesicles derived from hypoxia-preconditioned bone marrow mesenchymal stem cells ameliorate lower limb ischemia by delivering miR-34c(2023/02/02)
作者：Xitao Peng, Junhua Liu, Lijun Ren
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-023-04666-7
影响因子 ：4.300
-
Exosome miRNA-203 promotes M1 macrophage polarization and inhibits prostate cancer tumor progression(2023/10/09)
作者：Liansheng Zhang, Qichao Chen, Hongtao Zong
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-023-04854-5
影响因子 ：4.300
引用产品：CL-0233
-
Macrophage-derived exosomes regulate gastric cancer cell oxaliplatin resistance by wrapping circ 0008253(2022/11/23)
作者：Dandan Yu, Zhiwei Chang, Xiaolei Liu, Pengfei Chen, Huixian Zhang, Yanru Qin
期刊：CELL CYCLE
DOI：10.1080/15384101.2022.2146839
影响因子 ：4.300
-
Oral Cancer Stem Cell-Derived Small Extracellular Vesicles Promote M2 Macrophage Polarization and Suppress CD4+ T-Cell Activity by Transferring UCA1 and Targeting LAMC2(2022/11/28)
作者：Lan Wu, Sai Ye, Yilin Yao, Chenping Zhang, Wei Liu
期刊：Stem Cells International
影响因子 ：4.300
-
The bone mesenchymal stem cell-derived exosomal miR-146a-5p promotes diabetic wound healing in mice via macrophage M1/M2 polarization(2023/10/18)
作者：Xijie Zhou, Chenhao Ye, Liangfu Jiang
期刊：MOLECULAR AND CELLULAR ENDOCRINOLOGY
影响因子 ：4.100
引用产品：CL-0233
-
ADAR1 is targeted by miR-143 to regulate IL-1β-induced endothelial activation through the NFκB pathway(2017/5/17)
作者：Yuanzhuo Chen, Hu Peng, Shuqin Zhou
期刊：International Journal Of Biochemistry & Cell Biology
DOI：10.1016/j.biocel.2017.05.021
影响因子 ：4.000
-
In vitro and Intracellular Antibacterial Activity of Sudapyridine (WX-081) Against Tuberculosis(2023/01/09)
作者：Hua Xiao, Xia Yu, Yuanyuan Shang
期刊：Infection and Drug Resistance
影响因子 ：3.900
引用产品：CL-0233
-
Macrophages-derived exo-miR-4449 induced by Cryptococcus affects HUVEC permeability and promotes pyroptosis in BEAS-2B via the HIC1 pathway(2023/11/22)
作者：Xiaohua Li, Junping Xu, Xin Lin
期刊：CYTOKINE
DOI：10.1016/j.cyto.2023.156441
影响因子 ：3.800
引用产品：CL-0233
-
GLIS3, a novel prognostic indicator of gastric adenocarcinoma, contributes to the malignant biological behaviors of tumor cells via modulating TGF-β1/TGFβR1/Smad1/5 signaling pathway(2023/08/30)
作者：Yue Zhang, Bo Wang, Hui Song
期刊：CYTOKINE
DOI：10.1016/j.cyto.2023.156342
影响因子 ：3.800
-
Lactobacillus casei combined with Lactobacillus reuteri alleviate pancreatic cancer by inhibiting TLR4 to promote macrophage M1 polarization and regulate gut microbial homeostasis(2023/10/30)
作者：Zemin Zhu, Bo Yi, Zikai Tang
期刊：BMC CANCER
DOI：10.1186/s12885-023-11557-z
影响因子 ：3.800
引用产品：CL-0233
-
Calycosin represses AIM2 inflammasome-mediated inflammation and pyroptosis to attenuate monosodium urate-induced gouty arthritis through NF-κB and p62-Keap1 pathways(2022/09/07)
作者：Jing Tian, Dapeng Zhou, Liangbi Xiang
期刊：DRUG DEVELOPMENT RESEARCH
影响因子 ：3.800
-
Development of alternative herbals remedy for gastric cancer based on transcriptomic analysis of immune infiltration and ferroptosis(2023/03/03)
作者：Mingyue Li, Jie Tao, Rui Qian
期刊：Frontiers in Genetics
DOI：10.3389/fgene.2023.1086368
影响因子 ：3.700
引用产品：CL-0233
-
Integrated bioinformatic analyses investigate macrophage-M1-related biomarkers and tuberculosis therapeutic drugs(2023/02/08)
作者：Siqi Deng, Shijie Shen, Keyu Liu
期刊：Frontiers in Genetics
DOI：10.3389/fgene.2023.1041892
影响因子 ：3.700
引用产品：CL-0233
-
In Vitro Antimicrobial Activities of Tigecycline, Eravacycline, Omadacycline, and Sarecycline against Rapidly Growing Mycobacteria | Microbiology Spectrum(2022/12/08)
作者：Tingting Zhang, Jian Du, Lingling Dong
期刊：Microbiology Spectrum
影响因子 ：3.700
引用产品：CL-0233
-
Chemical Syntheses and Biological Evaluation of CXCL14 and Its Site-Selectively Modified Methionine Sulfoxide-Containing Derivatives(2019/12/9)
作者：Zonghui Cai, Qijia Wei, Xiujuan Li
期刊：Journal Of Organic Chemistry
影响因子 ：3.600
引用产品：CL-0233
-
Mesenchymal stem cell exosomal tsRNA-21109 alleviate systemic lupus erythematosus by inhibiting macrophage M1 polarization(2021/08/28)
作者：Rui Dou, Xiulei Zhang, Xiangdong Xu
期刊：Molecular Immunology
DOI：10.1016/j.molimm.2021.08.015
影响因子 ：3.600
-
Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway(2024/01/12)
作者：Dong Yuan, Zhipeng Zheng, Cheng Shen
期刊：MOLECULAR IMMUNOLOGY
DOI：10.1016/j.molimm.2024.01.002
影响因子 ：3.600
引用产品：CL-0233
-
MicroRNA miR-181d-5p regulates the MAPK signaling pathway by targeting mitogen-activated protein kinase 8 (MAPK8) to improve lupus nephritis(2023/11/04)
作者：Fu Chai, Huixin Peng, Linxiu Qin
期刊：GENE
DOI：10.1016/j.gene.2023.147961
影响因子 ：3.500
引用产品：CL-0233
-
Wilforlide A ameliorates the progression of rheumatoid arthritis by inhibiting M1 macrophage polarization(2021/11/2)
作者：Yunxiang Cao, Jian Liu, Chuanbing Huang
期刊：Journal Of Pharmacological Sciences
DOI：10.1016/j.jphs.2021.10.005
影响因子 ：3.500
-
Trimethylamine N-oxide promotes oxidative stress and lipid accumulation in macrophage foam cells via the Nrf2/ABCA1 pathway(2023/11/07)
作者：ZhiSheng Luo, XiaoChen Yu, Chao Wang
期刊：JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
DOI：10.1007/s13105-023-00984-y
影响因子 ：3.400
引用产品：CL-0233
-
Blapsimidazolium A: A new imidazolium carboxylate derivative with anti-inflammatory activity from medicinal insect Blaps rynchopetera(2022/12/05)
作者：Jianrong Luo, Jia Liu, Tingshun Luo
期刊：FITOTERAPIA
DOI：10.1016/j.fitote.2022.105386
影响因子 ：3.400
-
Alkannin exerts antitumor properties in cutaneous squamous cell carcinoma by inducing apoptosis and shifting the M1/M2 polarization of tumor-associated macrophages by upregulating PTEN(2022/11/11)
作者：Zhong-Zhao Zhang, Chang-Hui Wen, Min Jia, Hong-Qiang Zhang, Shao-Qin Sun
期刊：KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
影响因子 ：3.300
-
Understanding Competitive Endogenous RNA Network Mechanism in Type 1 Diabetes Mellitus Using Computational and Bioinformatics Approaches(2021/9/8)
作者：Xuanzi Yi, Xu Cheng
期刊：Diabetes Metabolic Syndrome and Obesity-Target & Therapy
影响因子 ：3.300
引用产品：CL-0233
-
Picroside II alleviates DSS-induced ulcerative colitis by suppressing the production of NLRP3 inflammasomes through NF-κB signaling pathway(2022/03/23)
作者：Huixiang Yao,Jun Yan,Li Yin
期刊：Immunopharmacology And Immunotoxicology
DOI：10.1080/08923973.2022.2054425
影响因子 ：3.300
引用产品：CL-0233
-
Regulation of Atherosclerosis by Toll-Like Receptor 4 Induced by Serum Amyloid 1: A Systematic In Vitro Study.(2022/09/15)
作者：Jinhui Chen, Gang Liu, Yan Hong
期刊：Biomed Research International
影响因子 ：3.246
-
Echinococcus granulosus cyst fluid inhibits inflammatory responses through inducing histone demethylase KDM5B in macrophages(2023/09/09)
作者：Xiaopeng Wang, Ruolin Lin, Chunxue Fu
期刊：Parasites & Vectors
DOI：10.1186/s13071-023-05948-1
影响因子 ：3.200
引用产品：CL-0233
-
Design, Synthesis and Structure–Activity Relationship Studies on Erianin Analogues as Pyruvate Carboxylase (PC) Inhibitors Against Hepatocellular Carcinoma Cells(2023/08/07)
作者：Hailong Shi, Jinlian Yang, Zeen Qiao
期刊：ORGANIC & BIOMOLECULAR CHEMISTRY
影响因子 ：3.200
引用产品：CL-0233
-
(3α)-3-(tiglinoyloxy)-ent-kaur-16-en-19-oic acid, isolated from Wedelia trilobata L., exerts an anti-inflammatory effect via the modulation of NF-κB, MAPK and mTOR pathway and autophagy in LPS-stimulated macrophages(2021/3/9)
作者：Jingwen Xu, Zhe Wang, Lianlian Sun
期刊：Toxicology In Vitro
影响因子 ：3.200
引用产品：CL-0233
-
Tumor‑associated macrophage‑derived exosomes promote EGFR‑TKI resistance in non‑small cell lung cancer by regulating the AKT, ERK1/2 and STAT3 signaling pathways(2022/08/24)
作者：Shiyang Yuan, Wenjun Chen, Jian Yange
期刊：Oncology Letters
影响因子 ：2.900
引用产品：CL-0233
-
A systematic strategy for investigating the pharmacological effects and mechanism of traditional Chinese medicinal formula: Guilin Xiguashuang as a case(2023/09/11)
作者：Jianing Zhang, Yue Ren, Yanan Liu
期刊：FUNDAMENTAL & CLINICAL PHARMACOLOGY
影响因子 ：2.900
引用产品：CL-0233
-
Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia(2023/12/12)
作者：Fahui Xie, Jia Qu, Dainan Lin
期刊：MOLECULAR BIOLOGY REPORTS
DOI：10.1007/s11033-023-08994-1
影响因子 ：2.800
引用产品：CL-0233
-
Clinical Significance of Apela in Acute Cardiorenal Insuffiency of Chronic Heart Failure(2024/01/18)
作者：Yani Zong, Yajie Wang, Yuexin Hu
期刊：KIDNEY & BLOOD PRESSURE RESEARCH
影响因子 ：2.800
引用产品：CL-0233
-
Tyrosine kinase nonreceptor 1 (TNK1) knockdown ameliorates hemorrhage shock-induced kidney injury via inhibiting macrophage M1 polarization(2021/11/17)
作者：Miaolong Tang, Jimin Cai, Yan Wang
期刊：3 BIOTECH
DOI：10.1007/s13205-021-03042-w
影响因子 ：2.800
引用产品：CL-0233
-
Scutellaria baicalensis Pith-decayed Root Inhibits Macrophage-related Inflammation Through the NF-κB/NLRP3 Pathway to Alleviate LPS-induced Acute Lung Injury(2022/11/07)
作者：Fanglei Zhang, Chang Ke, Zhongshi Zhou, Kang Xu, Yan Wang, Yanju Liu, Jiyuan Tu
期刊：PLANTA MEDICA
影响因子 ：2.700
引用产品：CL-0233
-
IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway(2023/03/03)
作者：Juan Gao, Shiqi Suo, Jingxia Li
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.700
-
Identification of Interleukin-1-Beta Inhibitors in Gouty Arthritis Using an Integrated Approach Based on Network Pharmacology, Molecular Docking, and Cell Experiments(2022/09/19)
作者：Liying Zeng, Zekun Lin, Pan Kang
期刊：Evidence-based Complementary and Alternative Medicine
影响因子 ：2.650
引用产品：CL-0233
-
LSD1 knockdown confers protection against osteoclast formation by reducing histone 3 lysine 9 monomethylation and dimethylation in ITGB3 promoter(2023/07/07)
作者：Dongping Yu, Zhen Li, Jie Cao
期刊：ACTA HISTOCHEMICA
DOI：10.1016/j.acthis.2023.152073
影响因子 ：2.500
引用产品：CL-0233
-
The synergistic Reduning and cefmetazole sodium treatment of severe pneumonia is mediated by the AhR-Src-STAT3 pathway(2022/02/01)
作者：Shanjun Luo, Lianfang Gan, Shengxing Liu
期刊：Journal of Thoracic Disease
影响因子 ：2.500
-
MiR-223-3p and miR-22-3p inhibit monosodium urate-induced gouty inflammation by targeting NLRP3(2021/3/1)
作者：Xiang Wang, Jingwei Chi, Bingzi Dong
期刊：International Journal of Rheumatic Diseases
影响因子 ：2.500
引用产品：CL-0233
-
Comparison of the different monosodium urate crystals in the preparation process and pro-inflammation(2023/08/08)
作者：Fei Yan, Hui Zhang, Xuan Yuan
期刊：Advances in Rheumatology
DOI：10.1186/s42358-023-00307-1
影响因子 ：2.300
引用产品：CL-0233
-
Neutrophil extracellular traps induce the bone erosion of gout(2022/12/26)
作者：Ertao Jia, Zhiling Li, Hongling Geng
期刊：BMC MUSCULOSKELETAL DISORDERS
DOI：10.1186/s12891-022-06115-w
影响因子 ：2.300
引用产品：CL-0233
-
Long non-coding RNA GAS5 knockdown facilitates proliferation and impedes apoptosis by regulating miR-128-3p/FBLN2 axis in ox-LDL-induced THP-1 cells(2021/1/1)
作者：Zijian Shen, Haigang Li
期刊：Clinical Hemorheology And Microcirculation
影响因子 ：2.100
-
Luteolin suppresses the growth of colon cancer cells by inhibiting the IL-6/STAT3 signaling pathway.(2022/08/01)
作者：Jingwen Jiang, Fengting Zhu, Hui Zhang
期刊：Journal of Gastrointestinal Oncology
影响因子 ：2.100
引用产品：CL-0233
-
Human umbilical cord mesenchymal stem cells overexpressing RUNX1 promote tendon-bone healing by inhibiting osteolysis, enhancing osteogenesis and promoting angiogenesis(2024/01/05)
作者：Dan Guo, Jian Yang, Dianwei Liu
期刊：Genes & Genomics
DOI：10.1007/s13258-023-01478-3
影响因子 ：2.100
引用产品：CL-0233
-
Exosomes Promote Atherosclerosis Progression by Regulating Circ_100696/miR-503-5p/PAPPA Axis-Mediated Vascular Smooth Muscle Cells Proliferation and Migration(2023/09/30)
作者：Jing Liu, Xiangyang Zhang, Zhaoxia Yu
期刊：International Heart Journal
影响因子 ：1.500
