产品中心Cell Resources
联系我们CONTACT US
400-999-210024小时服务热线
产品概述
名称 | U251 (人胶质瘤细胞) (STR鉴定正确) |
别称 | U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 成纤维细胞样 |
生长培养基 | DMEM+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | U251细胞源自一位患者的胶质母细胞瘤组织。 |
年龄(性别) | 75岁 |
组织来源 | 脑组织 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胶质瘤细胞 |
倍增时间 | ~24 hours |
保藏机构 | ECACC; 09063001 |
STR鉴定
-
STR位点信息
Amelogenin X CSF1PO 11,12 D2S1338 22,24 D3S1358 16,17 D5S818 11,12 D7S820 10,12 D8S1179 13,15 D13S317 10,11 D16S539 12 D18S51 13 D19S433 13,15 D21S11 29 FGA 21,25 PentaD 12 PentaE 7,10 TH01 9.3 TPOX 8 vWA 16,18 D6S1043 12 D12S391 17,22 D2S441 11 -
STR鉴定图
-
参考文献
-
Sphingosine kinase 1 promotes growth of glioblastoma by increasing inflammation mediated by the NF-κB /IL-6/STAT3 and JNK/PTX3 pathways(2022/09/29)
作者:Wan Li, Hongqing Cai, Liwen Ren
期刊:Acta Pharmaceutica Sinica B
DOI:10.1016/j.apsb.2022.09.012
影响因子 :14.500
-
Chitinase-3 like-protein-1 promotes glioma progression via the NF-κB signaling pathway and tumor microenvironment reprogramming.(2022/10/03)
作者:Ting Zhao, Jianming Zeng, Yujie Xu
期刊:Theranostics
影响因子 :12.400
-
Epigenetically regulated lncRNAs dissect the intratumoural heterogeneity and facilitate immune evasion of glioblastomas(2023/03/05)
作者:Dahua Xu, Meng Cao, Bo Wang, Xiaoman Bi
期刊:Theranostics
影响因子 :12.400
-
Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma(2020/07/16)
作者:Junhui Liu, Lun Gao, Na Zhan
期刊:Journal Of Experimental & Clinical Cancer Research
DOI:10.1186/s13046-020-01641-8
影响因子 :11.300
-
Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide resistance in glioma(2021/05/11)
作者:Chenyu Ding, Xuehan Yi, Xiangrong Chen
期刊:Journal Of Experimental & Clinical Cancer Research
DOI:10.1186/s13046-021-01942-6
影响因子 :11.300
-
circMMD reduction following tumor treating fields inhibits glioblastoma progression through FUBP1/FIR/DVL1 and miR-15b-5p/FZD6 signaling(2023/03/17)
作者:Shengchao Xu, Chengke Luo, Dikang Chen
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-023-02642-z
影响因子 :11.300
引用产品:CL-0237
-
Histone demethylase JMJD1C promotes the polarization of M1 macrophages to prevent glioma by upregulating miR-302a(2021/09/26)
作者:Chuanhong Zhong, Bei Tao, Feilong Yang
期刊:Clinical and Translational Medicine
DOI:10.1002/ctm2.424
影响因子 :10.600
引用产品:CL-0237
-
Genome-wide CRISPR/Cas9 screening identifies CARHSP1 responsible for radiation resistance in glioblastoma(2021/07/21)
作者:Guodong Zhu, Jing Yu, Zhengyu Sun
期刊:Cell Death & Disease
DOI:10.1038/s41419-021-04000-3
影响因子 :9.000
-
MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses(2022/03/12)
作者: JiajieTu, Yilong Fang, Dafei Han
期刊:Oncogene
DOI:10.1038/s41388-022-02236-7
影响因子 :8.000
-
The development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1(2023/06/21)
作者:Haojie Cheng, Jie Yuan, Chaozhu Pei
期刊:Cell and Bioscience
DOI:10.1186/s13578-023-01059-7
影响因子 :7.500
-
A novel prognostic related lncRNA signature associated with amino acid metabolism in glioma(2023/04/11)
作者:Qiang Lei, Bo Yuan, Kun Liu
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1014378
影响因子 :7.300
-
Neogenin suppresses tumor progression and metastasis via inhibiting Merlin/YAP signaling(2023/02/06)
作者:Xiaohan Hu, Li Li, Fang Li
期刊:Cell Death Discovery
DOI:10.1038/s41420-023-01345-w
影响因子 :7.000
-
E2F2 drives glioma progression via PI3K/AKT in a PFKFB4-dependent manner(2021/03/24)
作者:Longzhou Zhang, Zengjin Liu, Yang Dong
期刊:Life Sciences
影响因子 :6.780
-
N-2-(phenylamino) benzamide derivatives as novel anti-glioblastoma agents: Synthesis and biological evaluation(2021/09/10)
作者:Junfang Li, Xiaoling Hu, Tian Luo
期刊:European Journal Of Medicinal Chemistry
DOI:10.1016/j.ejmech.2021.113817
影响因子 :6.700
-
Design, synthesis, and biological evaluation of novel spirocyclic compounds as potential anti-glioblastoma agents(2023/06/25)
作者:Heping Zhu, Xiaomin Song, Yihui Pan
期刊:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1016/j.ejmech.2023.115595
影响因子 :6.700
-
Carbon Ion Irradiation Downregulates Notch Signaling in Glioma Cell Lines, Impacting Cell Migration and Spheroid Formation(2022/10/24)
作者:Vivek Kumar, Mohit Vashishta, Lin Kong
期刊:Cells
影响因子 :6.000
-
Overexpression of GINS4 is associated with poor prognosis and survival in glioma patients(2021/09/23)
作者:Binfeng Liu, Zhendong Liu, Yanbiao Wang
期刊:Molecular Medicine
DOI:10.1186/s10020-021-00378-0
影响因子 :5.700
-
Overexpressed XRCC2 as an independent risk factor for poor prognosis in glioma patients(2021/05/29)
作者:Zhendong Liu, Wang Zhang, Xingbo Cheng
期刊:Molecular Medicine
DOI:10.1186/s10020-021-00316-0
影响因子 :5.700
-
Nifuroxazide inhibits the growth of glioblastoma and promotes the infiltration of CD8 T cells to enhance antitumour immunity(2023/03/14)
作者:Xinzhuang Wang, Junyi Ye, Ming Gao
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2023.109987
影响因子 :5.600
-
RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12(2022/11/15)
作者:Liang Liu, Xuelan Zhou, Shan Cheng, Yuyuan Ge, Baomin Chen, Jia Shi, Haoran Li, Suwen Li, Yongdong Li, Jiaqi Yuan, Anyi Wu, Xinglei Liu, Shilu Huang, Zhipeng Xu, Jun Dong
期刊:CNS Neuroscience & Therapeutics
影响因子 :5.500
引用产品:CL-0012 CL-0233 CL-0237 CL-0458 CL-0578 CL-0583 CP-H122
-
ITGB3BP is a potential biomarker associated with poor prognosis of glioma( 2021/12/24)
作者:Zhendong Liu, Binfeng Liu, Lu Bian
期刊:Journal of Cellular and Molecular Medicine
影响因子 :5.300
-
lncRNA TUSC7 sponges miR-10a-5p and inhibits BDNF/ERK pathway to suppress glioma cell proliferation and migration(2023/04/14)
作者:Runhui Wang, Jia Wang, Yuanyu Wang
期刊:Aging-US
影响因子 :5.200
-
LINC01087 inhibits glioma cell proliferation and migration, and increases cell apoptosis via miR-384/Bcl-2 axis(2021/08/30)
作者:Yaohui Tian, Linwei Jia, Zhifeng Liu
期刊:Aging-US
影响因子 :5.200
引用产品:CL-0237
-
FDX1 serves as a prognostic biomarker and promotes glioma progression by regulating the immune response(2023/06/10)
作者:Guangying Zhang, Liangfang Shen, Zhanzhan Li
期刊:Aging-US
影响因子 :5.200
-
Isobavachalcone’s Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3(2022/09/02)
作者:Yueshan Wu, Jing Chang, Juanjuan Ge
期刊:MOLECULAR NEUROBIOLOGY
DOI:10.1007/s12035-022-03010-2
影响因子 :5.100
-
Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway(2023/06/02)
作者:Lei Zhang, Peng Luo, Xinggang Mao
期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
DOI:10.1016/j.bbamcr.2023.119509
影响因子 :5.100
引用产品:164210-50 CL-0012 CL-0237 CL-0238 CL-0458 CL-0583 PB180120 PM150210 PM150410
-
GD2 CAR-T cells in combination with Nivolumab exhibit enhanced antitumor efficacy(2023/03/24)
作者:Guangji Zhang, Yu Zhao, Zhongfeng Liu
期刊:Translational Oncology
DOI:10.1016/j.tranon.2023.101663
影响因子 :5.000
-
Circular RNA 0010117 promotes aggressive glioblastoma behavior by regulating the miRNA-6779-5p/SPEN axis(2022/09/07)
作者:Xuanyong Yang, Yue Liu, Xinhui Zhou
期刊:Translational Oncology
DOI:10.1016/j.tranon.2022.101515
影响因子 :5.000
-
LINC01088 promotes the growth and invasion of glioma cells through regulating small nuclear ribonucleoprotein polypeptide A transcription(2022/04/07)
作者:Tao Peng, Dongliang Chen, Shilan Chen
期刊:Bioengineered.
DOI:10.1080/21655979.2022.2051786
影响因子 :4.900
-
Integration analysis of single-cell and spatial transcriptomics reveal the cellular heterogeneity landscape in glioblastoma and establish a polygenic risk model(2023/06/15)
作者:Yaxuan Liu, Zhenyu Wu, Yueyuan Feng
期刊:Frontiers in Oncology
影响因子 :4.700
-
CASP6 predicts poor prognosis in glioma and correlates with tumor immune microenvironment.(2022/09/02)
作者:Kai Guo, Jiahui Zhao, Qianxu Jin
期刊:Frontiers in Oncology
影响因子 :4.700
-
The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells(2021/11/18)
作者:Dong Xuchen, Zhang Peng, Liu Liang
期刊:Frontiers in Oncology
影响因子 :4.700
-
Long Non-Coding RNA H19 Regulates Glioma Cell Growth and Metastasis via miR-200a-Mediated CDK6 and ZEB1 Expression(2021/11/2)
作者:Xuezhu Chen, Yuhong Li, Chenghai Zuo
期刊:Frontiers in Oncology
影响因子 :4.700
-
The overexpression and clinical significance of TBX15 in human gliomas(2023/06/16)
作者:Dongming Yan, Yaping Yu, Qiongwei Ni
期刊:Scientific Reports
DOI:10.1038/s41598-023-36410-y
影响因子 :4.600
-
A Potential Anti-Glioblastoma Compound LH20 Induces Apoptosis and Arrest of Human Glioblastoma Cells via CDK4/6 Inhibition(2023/06/28)
作者:Yan Wang, Youbin Li, Dong Liu
期刊:MOLECULES
影响因子 :4.600
-
Daphnetin Improves Neuropathic Pain by Inhibiting the Expression of Chemokines and Inflammatory Factors in the Spinal Cord and Interfering with Glial Cell Polarization(2023/02/06)
作者:Tianrui Zhang, Wulin Liang, Mingqian Zhang
期刊:Pharmaceuticals
影响因子 :4.600
-
Study on the Inhibitory Effect of Curcumin on GBM and Its Potential Mechanism(2021/06/28)
作者:Xiaotao Su, Shaohua Chen, Hongyu Lu
期刊:Drug Design Development and Therapy
影响因子 :4.319
引用产品:CL-0237
-
Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression(2019/9/12)
作者:Qiong Jiang, Qing Xie, Chengliang Hu
期刊:Bmc Cancer
影响因子 :3.800
-
Abietane diterpenoids from Phlegmariurus carinatus and their biological activities(2022/09/28)
作者:Jiawei Hu, Qiang Wang, Lin Liu
期刊:PHYTOCHEMISTRY
DOI:10.1016/j.phytochem.2022.113457
影响因子 :3.800
引用产品:CL-0237
-
Silencing lncRNA LINC01410 suppresses cell viability yet promotes apoptosis and sensitivity to temozolomide in glioblastoma cells by inactivating PTEN/AKT pathway via targeting miR-370-3p(2021/08/26)
作者:Tingkai Fu, Yunxue Yang, Zhenxin Mu
期刊:Immunopharmacology and Immunotoxicology
DOI:10.1080/08923973.2021.1966031
影响因子 :3.712
-
Circ_0001588 Upregulates ERBB4 to Promote Glioma Malignant Progression Through Sponging miR-1281(2022/01/04)
作者:Jun Wang, Juan Li, Peng Duan
期刊:Neurotoxicity Research
DOI:10.1007/s12640-021-00464-5
影响因子 :3.700
-
CircRNA circ_POSTN promotes the malignancy of glioma by regulating the miR-433-3p/SPARC axis(2022/12/01)
作者:Xiangting Hua, Chaoyong Zhang, Yongfeng Ba
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-022-01126-x
影响因子 :3.600
-
EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR(2022/01/17)
作者:Xiaoli Li, Chengmou Wang, Guanghui Chen
期刊: Metabolic Brain Disease
DOI:10.1007/s11011-021-00899-x
影响因子 :3.600
引用产品:164210 CL-0012 CL-0237 CL-0238 CL-0583 PB180120 PM150210
-
Circular RNA circ_0000741/miR-379-5p/TRIM14 signaling axis promotes HDAC inhibitor (SAHA) tolerance in glioblastoma(2023/03/11)
作者:Liang Meng, Yuefei Wang, Qin Tu
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-023-01184-9
影响因子 :3.600
-
EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR(2022/01/17)
作者:Xiaoli Li, Chengmou Wang, Guanghui Chen
期刊: Metabolic Brain Disease
DOI:10.1007/s11011-021-00899-x
影响因子 :3.600
引用产品:164210 CL-0012 CL-0237 CL-0238 CL-0583 PB180120 PM150210
-
Hsa_circ_0043949 reinforces temozolomide resistance via upregulating oncogene ITGA1 axis in glioblastoma(2022/10/27)
作者:Xuzhao Li, Nianhua Wang, Haibin Leng
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-022-01069-3
影响因子 :3.600
-
Propofol inhibits glioma progression by regulating circMAPK4/miR-622/HOXA9 axis(2022/11/03)
作者:Xiao, Gaopeng, Yu, Liuqiong, Tan, Wenmin, Yang, Hao, Li, Wensen, Xia, Rongzhou, Li, Yujin
期刊:METABOLIC BRAIN DISEASE
DOI:10.1007/s11011-022-01099-x
影响因子 :3.600
-
Deubiquitination of TNKS1 Regulates Wnt/β-Catenin to Affect the Expression of USP25 to Promote the Progression of Glioma(2022/04/11)
作者:Bin Tang, Hai Luo, Shenhao Xie
期刊:DISEASE MARKERS
影响因子 :3.464
-
Inhibitory effect of gefitinib derivative LPY‑9 on human glioma(2021/7/2)
作者:Yuchen Sun, Liangzhao Chu, Huijuan Wang
期刊:Molecular Medicine Reports
影响因子 :3.400
引用产品:CL-0237
-
Novel tumor necrosis factor-related long non-coding RNAs signature for risk stratification and prognosis in glioblastoma(2023/04/20)
作者:Shengrong Long, Bingbing Wu, Liu Yang
期刊:Frontiers in Neurology
DOI:10.3389/fneur.2023.1054686
影响因子 :3.400
-
FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling(2018/11/13)
作者:Qinchen Cao, Xinxin Wang, Yonggang Shi
期刊:Molecular Medicine Reports
影响因子 :3.400
-
Sevoflurane Represses Proliferation and Migration of Glioma Cells by Regulating the ANRIL/let-7b-5p Axis(2020/8/19)
作者:Yufeng Gao, Hui Ma, Dongnan Hou
期刊:Cancer Biother And Radiopharm
影响因子 :3.400
引用产品:CL-0237
-
Enhanced Glycolysis Confers Resistance Against Photon but Not Carbon Ion Irradiation in Human Glioma Cell Lines(2023/01/03)
作者:Mohit Vashishta, Vivek Kumar, Chandan Guha
期刊:Cancer Management and Research
影响因子 :3.300
引用产品:CL-0237
-
VSIG4 Silencing Inhibits Glioblastoma Growth by Regulating the JAK2/STAT3 Pathway(2023/06/02)
作者:Congying Zheng, Chengliang Mao, Kai Tang
期刊:Neuropsychiatric Disease and Treatment
影响因子 :3.200
-
CFTR activation suppresses glioblastoma cell proliferation, migration and invasion(2018/11/17)
作者:Xiao Zhong, Hongqi Chen, Xiuling Yang
期刊:Biochemical and Biophysical Research Communications
DOI:10.1016/j.bbrc.2018.12.080
影响因子 :3.100
-
Neuregulin 1 enhances cell adhesion molecule L1 like expression levels and promotes malignancy in human glioma(2020/4/21)
作者:Wenwen Lin, Guanyong Ou, Jiazhe Lin
期刊:Oncology Letters
影响因子 :2.900
-
Neuregulin 1 enhances cell adhesion molecule L1 like expression levels and promotes malignancy in human glioma(2020/04/21)
作者:Wenwen Lin, Guanyong Ou, Jiazhe Lin
期刊:Oncology Letters
影响因子 :2.900
引用产品:CL-0237
-
HNF4G accelerates glioma progression by facilitating NRP1 transcription(2023/02/01)
作者:Hongmin Che, Qi Zheng, Zijun Liao
期刊:Oncology Letters
影响因子 :2.900
-
Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway(2021/7/23)
作者:Dekang Wang, Aili Hu, Hao Peng
期刊:3 BIOTECH
DOI:10.1007/s13205-021-02922-5
影响因子 :2.800
-
MicroRNA-640 Inhibition Enhances the Chemosensitivity of Human Glioblastoma Cells to Temozolomide by Targeting Bcl2 Modifying Factor(2022/08/19)
作者:Shu Jiang, Chao Luo, Yongli Chen
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10264-x
影响因子 :2.400
引用产品:CL-0237
-
Construction of a novel microRNA-based signature for predicting the prognosis of glioma(2022/03/30)
作者:Gaoxin Liu, Xiaoming Rong, Xinrou Lin
期刊:International Journal Of Neuroscience
DOI:10.1080/00207454.2021.1993848
影响因子 :2.200
-
circ_0082375 promotes the progression of glioma by regulating Wnt7B(2021/01/01)
作者:Xianbing Meng, Hailong Tian, Wenqiang Guo
期刊:Translational Neuroscience
影响因子 :1.200
引用产品:CL-0237