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产品概述
| 名称 | U251 (人胶质瘤细胞) (STR鉴定正确) |
| 别称 | U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG |
| 背景描述 | U251细胞源自一位患者的胶质母细胞瘤组织。 |
| 种属 | 人 |
| 年龄（性别） | 75岁 |
| 组织来源 | 脑组织 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 成纤维细胞样 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胶质瘤细胞 |
| 生长培养基 | DMEM＋10% FBS＋1% P/S |
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 倍增时间 | ~24 hours |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 保藏机构 | ECACC; 09063001 |
STR鉴定
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STR位点信息
Amelogenin X,X CSF1PO 11,12 D2S1338 22,24 D3S1358 16,17 D5S818 11,12 D7S820 10,12 D8S1179 13,15 D13S317 10,11 D16S539 12,12 D18S51 13,13 D19S433 13,15 D21S11 29,29 FGA 21,25 PentaD 12,12 PentaE 7,10 TH01 9.3,9.3 TPOX 8,8 vWA 16,18 D6S1043 12,12 D12S391 17,22 D2S441 11,11 -
STR鉴定图
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参考文献
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Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma(2020/07/16)
作者：Junhui Liu, Lun Gao, Na Zhan
期刊：Journal Of Experimental & Clinical Cancer Research
DOI：10.1186/s13046-020-01641-8
影响因子 ：12.658
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Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide resistance in glioma(2021/05/11)
作者：Chenyu Ding, Xuehan Yi, Xiangrong Chen
期刊：Journal Of Experimental & Clinical Cancer Research
DOI：10.1186/s13046-021-01942-6
影响因子 ：12.658
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Genome-wide CRISPR/Cas9 screening identifies CARHSP1 responsible for radiation resistance in glioblastoma(2021/07/21)
作者：Guodong Zhu, Jing Yu, Zhengyu Sun
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-04000-3
影响因子 ：9.685
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Histone demethylase JMJD1C promotes the polarization of M1 macrophages to prevent glioma by upregulating miR-302a(2021/09/26)
作者：Chuanhong Zhong, Bei Tao, Feilong Yang
期刊：Clinical and Translational Medicine
DOI：10.1002/ctm2.424
影响因子 ：8.554
引用产品：CL-0237
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N-2-(phenylamino) benzamide derivatives as novel anti-glioblastoma agents: Synthesis and biological evaluation(2021/09/10)
作者：Junfang Li, Xiaoling Hu, Tian Luo
期刊：European Journal Of Medicinal Chemistry
DOI：10.1016/j.ejmech.2021.113817
影响因子 ：7.088
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Overexpression of GINS4 is associated with poor prognosis and survival in glioma patients(2021/09/23)
作者：Binfeng Liu, Zhendong Liu, Yanbiao Wang
期刊：Molecular Medicine
DOI：10.1186/s10020-021-00378-0
影响因子 ：6.376
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Overexpressed XRCC2 as an independent risk factor for poor prognosis in glioma patients(2021/05/29)
作者：Zhendong Liu, Wang Zhang, Xingbo Cheng
期刊：Molecular Medicine
DOI：10.1186/s10020-021-00316-0
影响因子 ：6.376
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LINC01087 inhibits glioma cell proliferation and migration, and increases cell apoptosis via miR-384/Bcl-2 axis(2021/08/30)
作者：Yaohui Tian, Linwei Jia, Zhifeng Liu
期刊：Aging-US
影响因子 ：5.9550
引用产品：CL-0237
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The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells(2021/11/18)
作者：Dong Xuchen, Zhang Peng, Liu Liang
期刊：Frontiers in Oncology
影响因子 ：5.7380
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Long Non-Coding RNA H19 Regulates Glioma Cell Growth and Metastasis via miR-200a-Mediated CDK6 and ZEB1 Expression(2021/11/2)
作者：Xuezhu Chen, Yuhong Li, Chenghai Zuo
期刊：Frontiers in Oncology
影响因子 ：5.7380
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ITGB3BP is a potential biomarker associated with poor prognosis of glioma( 2021/12/24)
作者：Zhendong Liu, Binfeng Liu, Lu Bian
期刊：Journal of Cellular and Molecular Medicine
影响因子 ：5.2950
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Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression(2019/9/12)
作者：Qiong Jiang, Qing Xie, Chengliang Hu
期刊：Bmc Cancer
影响因子 ：4.6380
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Inhibitory effect of gefitinib derivative LPY‑9 on human glioma(2021/7/2)
作者：Yuchen Sun, Liangzhao Chu, Huijuan Wang
期刊：Molecular Medicine Reports
影响因子 ：3.4230
引用产品：CL-0237
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FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling(2018/11/13)
作者：Qinchen Cao, Xinxin Wang, Yonggang Shi
期刊：Molecular Medicine Reports
影响因子 ：3.4230
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CFTR activation suppresses glioblastoma cell proliferation, migration and invasion(2018/11/17)
作者：Xiao Zhong, Hongqi Chen, Xiuling Yang
期刊：Biochemical and Biophysical Research Communications
DOI：10.1016/j.bbrc.2018.12.080
影响因子 ：3.3220
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Neuregulin 1 enhances cell adhesion molecule L1 like expression levels and promotes malignancy in human glioma(2020/4/21)
作者：Wenwen Lin, Guanyong Ou, Jiazhe Lin
期刊：Oncology Letters
影响因子 ：3.1110
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Neuregulin 1 enhances cell adhesion molecule L1 like expression levels and promotes malignancy in human glioma(2020/04/21)
作者：Wenwen Lin, Guanyong Ou, Jiazhe Lin
期刊：Oncology Letters
影响因子 ：3.111
引用产品：CL-0237
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Sevoflurane Represses Proliferation and Migration of Glioma Cells by Regulating the ANRIL/let-7b-5p Axis(2020/8/19)
作者：Yufeng Gao, Hui Ma, Dongnan Hou
期刊：Cancer Biother And Radiopharm
影响因子 ：3.0990
引用产品：CL-0237
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Tumor-promoting function of PIMREG in glioma by activating the β-catenin pathway(2021/7/23)
作者：Dekang Wang, Aili Hu, Hao Peng
期刊：3 BIOTECH
DOI：10.1007/s13205-021-02922-5
影响因子 ：2.8930
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circ_0082375 promotes the progression of glioma by regulating Wnt7B(2021/01/01)
作者：Xianbing Meng, Hailong Tian, Wenqiang Guo
期刊：Translational Neuroscience
影响因子 ：1.2639
引用产品：CL-0237
![NCI-H508[H508] (人结肠直肠腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0702-1.jpg)
