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| 名称 | U-87 MG (人脑星形胶质母细胞瘤细胞) (STR鉴定正确) |
| 别称 | U-87MG; U-87 MG; U87 MG; U-87-MG; U87-MG; U87MG; U-87; U87; 87 MG; 87MG |
| 背景描述 | U-87 MG细胞是由Ponten·J等建立，源于恶性神经胶质瘤；U-87 MG细胞裸鼠皮下接种可成瘤。 |
| 种属 | 人 |
| 年龄（性别） | 女 |
| 组织来源 | 脑星形胶质母细胞瘤 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胶质瘤细胞 |
| 生物安全等级 | 1 |
| 生长培养基 | MEM（含NEAA）＋10% FBS＋1% P/S |
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 倍增时间 | ~36-72 hours |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 致瘤性 | Yes, in nude mice inoculated subcutaneously with 1×10^7 cells. |
| 注意事项 | 该细胞容易聚团，可使用多聚-L-赖氨酸溶液包被后改善，建议提前配备多聚-L-赖氨酸溶液（货号 PB180523）。 |
| 保藏机构 | ATCC; HTB-14 ECACC; 89081402 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 10,11 D2S1338 20,23 D3S1358 16,17 D5S818 11,12 D7S820 8,9 D8S1179 10,11 D13S317 8,11 D16S539 12 D18S51 13 D19S433 15,15.2 D21S11 28,32.2 FGA 18,24 PentaD 9,14 PentaE 7,14 TH01 9.300000000000001 TPOX 8 vWA 15,17 D6S1043 11,18 D12S391 18,21 D2S441 10,11 -
STR鉴定图
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参考文献
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Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase(2021/08/05)
作者：Ximing Shao, Zhihao Ding, Wenhua Zhou
期刊：Nature Nanotechnology
DOI：10.1038/s41565-021-00952-x
影响因子 ：40.523
引用产品：CL-0016 CL-0101 CL-0103 CL-0150A CL-0150B CL-0236 CL-0238
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Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides(2022/08/06)
作者：Zhanchi Zhu, Yuanxin Zhai, Ying Hao
期刊：Journal of Extracellular Vesicles
影响因子 ：17.3370
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Controlling dielectric loss of biodegradable black phosphorus nanosheets by iron-ion-modification for imaging-guided microwave thermoacoustic therapy(2022/07/01)
作者：Xiaoyu Chen, Shanxiang Zhang, Jiaqian Liu
期刊：BIOMATERIALS
DOI：10.1016/j.biomaterials.2022.121662
影响因子 ：15.3040
引用产品：CL-0238
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Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma(2020/07/16)
作者：Junhui Liu, Lun Gao, Na Zhan
期刊：Journal Of Experimental & Clinical Cancer Research
DOI：10.1186/s13046-020-01641-8
影响因子 ：12.658
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Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide resistance in glioma(2021/05/11)
作者：Chenyu Ding, Xuehan Yi, Xiangrong Chen
期刊：Journal Of Experimental & Clinical Cancer Research
DOI：10.1186/s13046-021-01942-6
影响因子 ：12.658
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Profiling demethylase activity using epigenetically inactivated DNAzyme(2022/03/18)
作者：Juan Huang, Jiao Wang, Zhenkun Wu
期刊：Biosensors & Bioelectronics
DOI：10.1016/j.bios.2022.114186
影响因子 ：12.5450
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Chitinase-3 like-protein-1 promotes glioma progression via the NF-κB signaling pathway and tumor microenvironment reprogramming.(2022/10/03)
作者：Ting Zhao, Jianming Zeng, Yujie Xu
期刊：Theranostics
影响因子 ：11.6000
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MoS2 Quantum Dot@Polyaniline Inorganic–Organic Nanohybrids for in Vivo Dual-Modal Imaging Guided Synergistic Photothermal/Radiation Therapy(2016/09/07)
作者：Jinping Wang, Xiaoxiao Tan, Xiaojuan Pang
期刊：ACS Applied Materials & Interfaces
影响因子 ：10.3830
引用产品：CL-0016 CL-0101 CL-0103 CL-0150A CL-0150B CL-0236 CL-0238
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The miR-145–MMP1 axis is a critical regulator for imiquimod-induced cancer stemness and chemoresistance(2022/03/28)
作者：Shan Zhu, Ning Yang, Chao Niu
期刊：Pharmacological Research
DOI：10.1016/j.phrs.2022.106196
影响因子 ：10.3340
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Genome-wide CRISPR/Cas9 screening identifies CARHSP1 responsible for radiation resistance in glioblastoma(2021/07/21)
作者：Guodong Zhu, Jing Yu, Zhengyu Sun
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-04000-3
影响因子 ：9.685
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MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses(2022/03/12)
作者： JiajieTu, Yilong Fang, Dafei Han
期刊：Oncogene
DOI：10.1038/s41388-022-02236-7
影响因子 ：8.7560
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Carbon Ion Irradiation Downregulates Notch Signaling in Glioma Cell Lines, Impacting Cell Migration and Spheroid Formation(2022/10/24)
作者：Vivek Kumar, Mohit Vashishta, Lin Kong
期刊：Cells
影响因子 ：7.6660
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CAR-T-Cell Therapy for Solid Tumors Positive for Fibronectin Extra Domain B(2022/09/14)
作者：Zhijie Zhang, Chang Liu, Zhe Yang
期刊：Cells
影响因子 ：7.6660
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N-2-(phenylamino) benzamide derivatives as novel anti-glioblastoma agents: Synthesis and biological evaluation(2021/09/10)
作者：Junfang Li, Xiaoling Hu, Tian Luo
期刊：European Journal Of Medicinal Chemistry
DOI：10.1016/j.ejmech.2021.113817
影响因子 ：7.088
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Decreased RNA m6A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma(2022/02/15)
作者：Min Tao, Xiaoyu Li, Lei He
期刊：American Journal of Cancer Research
DOI：PMID:35261810
影响因子 ：5.9420
引用产品：CL-0238
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The Circ_0001367/miR-545-3p/LUZP1 Axis Regulates Cell Proliferation, Migration and Invasion in Glioma Cells(2021/11/18)
作者：Dong Xuchen, Zhang Peng, Liu Liang
期刊：Frontiers in Oncology
影响因子 ：5.7380
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Long Non-Coding RNA H19 Regulates Glioma Cell Growth and Metastasis via miR-200a-Mediated CDK6 and ZEB1 Expression(2021/11/2)
作者：Xuezhu Chen, Yuhong Li, Chenghai Zuo
期刊：Frontiers in Oncology
影响因子 ：5.7380
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Isobavachalcone’s Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3(2022/09/02)
作者：Yueshan Wu, Jing Chang, Juanjuan Ge
期刊：MOLECULAR NEUROBIOLOGY
DOI：10.1007/s12035-022-03010-2
影响因子 ：5.6820
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Tanshinone I induces apoptosis and protective autophagy in human glioblastoma cells via a reactive oxygen species‑dependent pathway(2020/02/13)
作者：Shangguan Jian, Liang Chen, Lian Minxue
期刊：International Journal of Molecular Medicine
影响因子 ：5.314
引用产品：CL-0238
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Circular RNA 0010117 promotes aggressive glioblastoma behavior by regulating the miRNA-6779-5p/SPEN axis(2022/09/07)
作者：Xuanyong Yang, Yue Liu, Xinhui Zhou
期刊：Translational Oncology
DOI：10.1016/j.tranon.2022.101515
影响因子 ：4.8030
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Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression(2019/9/12)
作者：Qiong Jiang, Qing Xie, Chengliang Hu
期刊：Bmc Cancer
影响因子 ：4.6380
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GPX8 as a Novel Prognostic Factor and Potential Therapeutic Target in Primary Glioma(2022/08/23)
作者：Zhaoshou Yang, Qin Yang, Xiaoxiao Sun
期刊：Journal of Immunology Research
影响因子 ：4.4930
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Linc01094 Accelerates the Growth and Metastatic-Related Traits of Glioblastoma by Sponging miR-126-5p(2020/10/6)
作者：Xinxing Li, Qi Yu
期刊：OncoTargets and Therapy
影响因子 ：4.3450
引用产品：CL-0238
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EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR(2022/01/17)
作者：Xiaoli Li, Chengmou Wang, Guanghui Chen
期刊： Metabolic Brain Disease
DOI：10.1007/s11011-021-00899-x
影响因子 ：3.6550
引用产品：164210 CL-0012 CL-0237 CL-0238 CL-0583 PB180120 PM150210
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EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR(2022/01/17)
作者：Xiaoli Li, Chengmou Wang, Guanghui Chen
期刊： Metabolic Brain Disease
DOI：10.1007/s11011-021-00899-x
影响因子 ：3.6550
引用产品：164210 CL-0012 CL-0237 CL-0238 CL-0583 PB180120 PM150210
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Deubiquitination of TNKS1 Regulates Wnt/β-Catenin to Affect the Expression of USP25 to Promote the Progression of Glioma(2022/04/11)
作者：Bin Tang, Hai Luo, Shenhao Xie
期刊：DISEASE MARKERS
影响因子 ：3.4640
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FOXG1 mediates the radiosensitivity of glioma cells through regulation of autophagy(2020/11/17)
作者：Ning Xiao, Churong Li, Wenjun Liao
期刊：International Journal Of Radiation Biology
DOI：10.1080/09553002.2021.1846816
影响因子 ：3.3520
引用产品：CL-0238
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CFTR activation suppresses glioblastoma cell proliferation, migration and invasion(2018/11/17)
作者：Xiao Zhong, Hongqi Chen, Xiuling Yang
期刊：Biochemical and Biophysical Research Communications
DOI：10.1016/j.bbrc.2018.12.080
影响因子 ：3.3220
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Long Noncoding RNA NEAT1 Suppresses Proliferation and Promotes Apoptosis of Glioma Cells Via Downregulating MiR-92b:(2020/1/14)
作者：Dongdong Liu, Zheng Zou, Gen Li
期刊：Cancer Control
影响因子 ：3.3020
引用产品：CL-0238
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Inhibition of proliferation and migration and induction of apoptosis in glioma cells by silencing TLR4 expression levels via RNA interference(2020/11/6)
作者：Yingzi Liu, Yingchao Ju, Jianghui Liu
期刊：Oncology Letters
影响因子 ：3.1110
引用产品：CL-0238
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miR-9-3p inhibits glioma cell proliferation and apoptosis by directly targeting FOXG1(2020/6/11)
作者：Jianwen Zhen, Hengxun Zhang, Hongzhi Dong
期刊：Oncology Letters
影响因子 ：3.1110
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Neuregulin 1 enhances cell adhesion molecule L1 like expression levels and promotes malignancy in human glioma(2020/4/21)
作者：Wenwen Lin, Guanyong Ou, Jiazhe Lin
期刊：Oncology Letters
影响因子 ：3.1110
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Effect of the interference with DRP1 expression on the biological characteristics of glioma stem cells(2021/3/2)
作者：Linna Zhang, Huimei Cao, Hong Tao
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.7510
引用产品：CL-0238
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Construction of a novel microRNA-based signature for predicting the prognosis of glioma(2022/03/30)
作者：Gaoxin Liu, Xiaoming Rong, Xinrou Lin
期刊：International Journal Of Neuroscience
DOI：10.1080/00207454.2021.1993848
影响因子 ：2.5900
