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产品概述
名称 | AGS (人胃腺癌细胞) (STR鉴定正确) |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
生长培养基 | Ham's F-12+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | AGS细胞源自一个未经治疗的切除肿瘤碎块;据报道,AGS细胞的植板率为34%。 |
年龄(性别) | 女;54岁 |
组织来源 | 胃;胃癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胃癌细胞 |
生物安全等级 | 2 |
倍增时间 | ~20-24 hours |
致瘤性 | Yes, in athymic BALB/c mice. |
保藏机构 | ATCC; CRL-1739 BCRC; 60102 BCRJ; 0311 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11,12 D2S1338 20,22 D3S1358 16 D5S818 9,12 D7S820 10,11 D8S1179 13 D13S317 12 D16S539 11,13 D18S51 13 D19S433 13.2,16 D21S11 29 FGA 23,24 PentaD 9,10 PentaE 13,16 TH01 6,7 TPOX 11,12 vWA 16,17 D6S1043 12 D12S391 19,20 D2S441 10,14 -
STR鉴定图
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参考文献
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AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination(2022/11/14)
作者:Zhao, Rou, He, Baoyu, Bie, Qingli, Cao, Jinghe, Lu, Haoran, Zhang, Zhixin, Liang, Jing, Wei, Li, Xiong, Huabao, Zhang, Bin
期刊:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI:10.1186/s13046-022-02532-w
影响因子 :11.300
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A sensitive and rapid electrochemical biosensor for sEV-miRNA detection based on domino-type localized catalytic hairpin assembly(2023/09/09)
作者:Wenbin Li, Wen Wang, Shihua Luo
期刊:JOURNAL OF NANOBIOTECHNOLOGY
DOI:10.1186/s12951-023-02092-x
影响因子 :10.200
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miR-497 defect contributes to gastric cancer tumorigenesis and progression via regulating CDC42/ITGB1/FAK/PXN/AKT signaling(2021/08/08)
作者:Lihui Zhang, Liwen Yao, Wei Zhou
期刊:Molecular Therapy-Nucleic Acids
DOI:10.1016/j.omtn.2021.07.025
影响因子 :8.800
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Neutrophil extracellular traps promote angiogenesis in gastric cancer(2023/07/21)
作者:Shifeng Yang, Boshi Sun, Jiacheng Li
期刊:Cell Communication and Signaling
DOI:10.1186/s12964-023-01196-z
影响因子 :8.400
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CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1(2022/11/12)
作者:Li, Dongbao, Wang, Yuhong, Dong, Chao, Chen, Tao, Dong, Anqi, Ren, Jiayu, Li, Weikang, Shu, Gege, Yang, Jiaoyang, Shen, Wenhao, Qin, Lei, Hu, Lin, Zhou, Jin
期刊:ONCOGENE
DOI:10.1038/s41388-022-02537-x
影响因子 :8.000
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Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis(2023/01/05)
作者:Chenggang Zhang, Guanxin Wei, Xiuxian Zhu
期刊:International Journal of Nanomedicine
影响因子 :8.000
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Compound Kushen Injection inhibits epithelial-mesenchymal transition of gastric carcinoma by regulating VCAM1 induced by the TNF signaling pathway(2023/07/17)
作者:Zhihong Huang, Chao Wu, Wei Zhou
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2023.154984
影响因子 :7.900
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Computed tomography-detected extramural venous invasion-related gene signature: a potential negative biomarker of immune checkpoint inhibitor treatment in patients with gastric cancer(2023/01/05)
作者:Hao Yang, Xinyi Gou, Caizhen Feng
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-022-03845-2
影响因子 :7.400
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Identification of lactylation related model to predict prognostic, tumor infiltrating immunocytes and response of immunotherapy in gastric cancer(2023/03/03)
作者:Hao Yang, Xiaoming Zou, Shifeng Yang
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1149989
影响因子 :7.300
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Effect of NETs/COX-2 pathway on immune microenvironment and metastasis in gastric cancer(2023/04/20)
作者:Ange Zhang, Xiaoming Zou, Shifeng Yang
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1177604
影响因子 :7.300
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A novel NAE/UAE dual inhibitor LP0040 blocks neddylation and ubiquitination leading to growth inhibition and apoptosis of cancer cells(2018/05/21)
作者:Peng Lu, Yahui Guo, Lijuan Zhu
期刊:European Journal Of Medicinal Chemistry
DOI:10.1016/j.ejmech.2018.05.027
影响因子 :6.700
引用产品:CL-0022
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Isorhamnetin Promotes MKN-45 Gastric Cancer Cell Apoptosis by Inhibiting PI3K-Mediated Adaptive Autophagy in a Hypoxic Environment(2021/07/16)
作者:Chenghao Li, Jiawei Li, Yan Li
期刊:Journal Of Agricultural And Food Chemistry
影响因子 :6.100
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Circ_0021087 acts as a miR-184 sponge and represses gastric cancer progression by adsorbing miR-184 and elevating FOSB expression(2021/06/02)
作者:Yin Yu, Hong Li, Chunhua Wu
期刊:European Journal Of Clinical Investigation
影响因子 :5.500
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Identification of 14 Differentially-Expressed Metabolism-Related Genes as Potential Targets of Gastric Cancer by Integrated Proteomics and Transcriptomics(2022/02/21)
作者:Yongxin Zhang, Wenwei Liu, Wei Feng
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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Long noncoding RNA PSMA3-AS1 functions as a competing endogenous RNA to promote gastric cancer progression by regulating the miR-329-3p/ALDOA axis(2023/07/04)
作者:Liang Kan, Meiqi Yang, Huijing Zhang
期刊:Biology Direct
DOI:10.1186/s13062-023-00392-8
影响因子 :5.500
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Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec498 Residue of Cytosolic Selenoprotein Thioredoxin Reductase(2023/09/28)
作者:Minghui Liu, Shibo Sun, Yao Meng
期刊:MOLECULES
影响因子 :4.600
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Depletion of hsa_circ_0000144 Suppresses Oxaliplatin Resistance of Gastric Cancer Cells by Regulating miR-502-5p/ADAM9 Axis(2021/04/20)
作者:Haifeng Gao, Jiajia Xu, Fen Qiao
期刊:OncoTargets and Therapy
影响因子 :4.345
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Effects and mechanisms of trifluridine alone or in combination with cryptotanshinone in inhibiting malignant biological behavior of gastric cancer(2023/06/04)
作者:Panquan Luo, Lixiang Zhang, Zhangming Chen
期刊:CELL CYCLE
DOI:10.1080/15384101.2023.2215678
影响因子 :4.300
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Cancer-associated fibroblast expression of glutamine fructose-6-phosphate aminotransferase 2 (GFPT2) is a prognostic marker in gastric cancer(2023/07/03)
作者:Shuo Yang, Guoli Li, Xin Yin
期刊:Journal of Pathology Clinical Research
DOI:10.1002/cjp2.333
影响因子 :4.100
引用产品:CL-0022 CL-0033 CL-0107 CL-0291 CL-0563 PM150110 PM150810
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LINC01224 accelerates malignant transformation via MiR-193a-5p/CDK8 axis in gastric cancer(2021/03/02)
作者:Hui Sun, Jihong Yan, Guangyu Tian
期刊:Cancer Medicine
影响因子 :4.000
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LINC_00355 promotes gastric cancer progression by upregulating PHF19 expression through sponging miR-15a-5p(2021/06/02)
作者:Jishui Zhang, Wenhao Lv, Yagang Liu
期刊:Bmc Cancer
DOI:10.1186/s12885-021-08227-3
影响因子 :3.800
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Unveiling DNA damage repair-based molecular subtypes, tumor microenvironment and pharmacogenomic landscape in gastric cancer(2023/04/14)
作者:Weiqi Kong, Zhiqiang Wang, Bingyi Wang
期刊:Frontiers in Genetics
DOI:10.3389/fgene.2023.1118889
影响因子 :3.700
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KRT18 Modulates Alternative Splicing of Genes Involved in Proliferation and Apoptosis Processes in Both Gastric Cancer Cells and Clinical Samples(2021/07/05)
作者:Biao Chen, Ximing Xu, Dandan Lin
期刊:Frontiers in Genetics
影响因子 :3.700
引用产品:CL-0022
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Demethylase FTO enhances the PI3K/Akt signaling to promote gastric cancer malignancy(2023/03/27)
作者:Yuxuan Zhu, Jing Yang, Yongxiang Li
期刊:MEDICAL ONCOLOGY
DOI:10.1007/s12032-023-01990-2
影响因子 :3.400
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ZNF521/EBF1 axis regulates AKR1B1 to promote the proliferation, migration, and invasion of gastric cancer cells(2022/11/17)
作者:Yu Cheng, Yi-Jiang Ni, Li-Ming Tang
期刊:KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
影响因子 :3.300
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Circ_0000419 acts as a tumor suppressor in gastric cancer development via regulating miR-300/RGMB axis(2023/07/20)
作者:Jiajun Lu, Yuan Zhou, Zhiheng Chen
期刊:International Journal of Clinical Oncology
DOI:10.1007/s10147-023-02379-x
影响因子 :3.300
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Circular RNA Circ_0006282 Promotes Cell Proliferation and Metastasis in Gastric Cancer by Regulating MicroRNA-144-5p/Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein β Axis(2021/1/27)
作者:Yunqi Hua, Hailong Wang, Haizhen Wang
期刊:Cancer Management and Research
影响因子 :3.300
引用产品:164210 164210-50 CL-0022 CL-0107 CL-0563 PB180120 PM150110
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Circ_0032821 Facilitates Gastric Cancer Cell Proliferation, Migration, Invasion and Glycolysis by Regulating MiR-1236-3p/HMGB1 Axis(2020/10/12)
作者:Lei Chen, Kun Chi, Huaguo Xiang
期刊:Cancer Management and Research
影响因子 :3.300
引用产品:164210 164210-50 CL-0022 CL-0107 CL-0169 CL-0292 CL-0563 PB180120 PM150110
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Achaete-scute complex-like 2 regulated inflammatory mechanism through Toll-like receptor 4 activating in stomach adenocarcinoma(2022/08/25)
作者:Enqi Zheng, Zhun Cai, Wangyong Li
期刊:World Journal of Surgical Oncology
DOI:10.1186/s12957-022-02722-y
影响因子 :3.200
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Circ_0026359 induces HOXA9 to regulate gastric cancer malignant progression through miR-140-3p(2022/08/22)
作者:Shuirong Lu, Jinlai Lu, Lang Liu
期刊:Applied Biological Chemistry
DOI:10.1186/s13765-022-00726-6
影响因子 :3.200
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Circ_0003159 upregulates LIFR expression through competitively binding to miR-221-3p/miR-222-3p to block gastric cancer development(2022/01/16)
作者:Liansheng Zheng, Boshi Yan, Guoliang Jin
期刊:Journal Of Molecular Histology
DOI:10.1007/s10735-021-10044-8
影响因子 :3.200
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Circ-RNF111 aggravates the malignancy of gastric cancer through miR-876-3p-dependent regulation of KLF12(2020/08/30)
作者:Guoxian Wu, Aimin Zhang, Yinglin Yang
期刊:World Journal of Surgical Oncology
DOI:10.1186/s12957-021-02373-5
影响因子 :3.200
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The GLI2/CDH6 axis enhances migration, invasion and mitochondrial fission of stomach adenocarcinoma cells(2023/07/24)
作者:Guangyi Liu, Huan Wang, Rui Ran
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.07.038
影响因子 :3.100
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Lidocaine Suppresses Gastric Cancer Development Through Circ_ANO5/miR-21-5p/LIFR Axis(2021/5/29)
作者:Enjian Guan, Hongrong Liu, Ning Xu
期刊:Digestive Diseases And Sciences
DOI:10.1007/s10620-021-07055-6
影响因子 :3.100
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Elastic net-based identification of GAMT as potential diagnostic marker for early-stage gastric cancer(2021/12/21)
作者:Congcong Gong, Mao Zhou, Yang Hu
期刊:Biochemical And Biophysical Research Communications
DOI:10.1016/j.bbrc.2021.12.055
影响因子 :3.100
引用产品:CL-0022
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Amentoflavone attenuates cell proliferation and induces ferroptosis in human gastric cancer by miR-496/ATF2 axis(2023/07/16)
作者:Fengying Tang, Yongpan Xu, Erpeng Gao
期刊:Chemical Biology & Drug Design
影响因子 :3.000
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Sinomenine regulates circTRPM7-related pathway to inhibit gastric cancer cell growth and metastasis(2023/07/26)
作者:Jingwei Yan, Jingqing Yang, Huifen Shen
期刊:Chemical Biology & Drug Design
影响因子 :3.000
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Flavonoid-Rich Extract of Oldenlandia diffusa (Willd.) Roxb. Inhibits Gastric Cancer by Activation of Caspase-Dependent Mitochondrial Apoptosis(2022/08/31)
作者:Jiayin Ling, Qiulan Wang, Haonan Liang
期刊:Chinese Journal of Integrative Medicine
影响因子 :2.900
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Syntheses and Preliminary Biological Evaluations of the Dibromopyrrole-Containing Marine Natural Products Agesasine A, Agesasine B, Longamide E and Various Congeners(2023/02/12)
作者:Chengzhi Chen, Tingting Yuan, Ping Lan
期刊:EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
影响因子 :2.800
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T-17, a spirostanol saponin, inhibits p53-independent proliferation and p53-dependent migration of gastric cancer cells(2021/03/26)
作者:Jingwen Xu, Yi Wang, Zhe Wang
期刊:Steroids
DOI:10.1016/j.steroids.2021.108828
影响因子 :2.700
引用产品:CL-0022
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MFAP2 enhances cisplatin resistance in gastric cancer cells by regulating autophagy(2023/06/07)
作者:Meng Li, Hongyi Zhang, Ronggui Zhang
期刊:PeerJ
影响因子 :2.700
引用产品:CL-0022
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SPI1 Mediates N-Myristoyltransferase 1 to Advance Gastric Cancer Progression via PI3K/AKT/mTOR Pathway(2023/03/17)
作者:Ping Qiu, Xing Li, Min Gong
期刊:Canadian Journal of Gastroenterology and Hepatology
影响因子 :2.700
引用产品:164210 CL-0001 CL-0022 CL-0107 CL-0292 CL-0563 PB180120 PM150110 PM150467 PM150510 PM150810
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Ubiquitin-specific protease 1 overexpression indicates poor prognosis and promotes proliferation, migration, and invasion of gastric cancer cells(2021/12/29)
作者:Debin Meng, Delong Li
期刊:Tissue & Cell
DOI:10.1016/j.tice.2021.101723
影响因子 :2.600
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NREP is a Diagnostic and Prognostic Biomarker, and Promotes Gastric Cancer Cell Proliferation and Angiogenesis(2022/09/12)
作者:Qian Li, Lei Fu, Daoyuan Wu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10276-7
影响因子 :2.400
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Knockdown circZNF131 Inhibits Cell Progression and Glycolysis in Gastric Cancer Through miR-186-5p/PFKFB2 Axis(2022/01/21)
作者:Xingjie Shen, Xiaoyan Zhu, Peixin Hu
期刊:Biochemical Genetics
DOI:10.1007/s10528-021-10165-5
影响因子 :2.400
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Circular RNA circ_0001017 Sensitizes Cisplatin-Resistant Gastric Cancer Cells to Chemotherapy by the miR-543/PHLPP2 Axis(2021/7/27)
作者:Jianmin Zhang, Wenzhang Zha, Changchun Qian
期刊:Biochemical Genetics
DOI:10.1007/s10528-021-10110-6
影响因子 :2.400
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Exosomal circPRRX1 functions as a ceRNA for miR-596 to promote the proliferation, migration, invasion, and reduce radiation sensitivity of gastric cancer cells via the upregulation of NF-κB activating protein(2022/10/05)
作者:Yuxin He, Liangjian Zheng, Mengzhen Yuan
期刊:ANTI-CANCER DRUGS
DOI:10.1097/CAD.0000000000001358
影响因子 :2.300
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Knockdown of kinesin family member 2C restricts cell proliferation and induces cell cycle arrest in gastric cancer(2022/11/30)
作者:Shuai Li, Yulian Ma, Chen Wu, Xinfang Hou, Shuai Li, Yulian Ma, Chen Wu, Xinfang Hou
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.000
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Circular RNA circ_SKA3 enhances gastric cancer development by targeting miR-520h(2022/09/22)
作者:Chuntao Wang, Hao Jiang, Jiaqun Peng
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.000
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Investigation of target genes and potential mechanisms related to compound Xiao-ai-fei honey ointment based on network pharmacology and bioinformatics analysis(2023/08/11)
作者:Abudurousuli Kayisaier, Talihati Ziruo, Hailati Sendaer
期刊:MEDICINE
DOI:10.1097/MD.0000000000034629
影响因子 :1.600
引用产品:CL-0022
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Silencing CDCA8 inhibits the proliferation and invasion of gastric cancer cells and induces apoptosis by blocking the Akt pathway(2022/01/17)
作者:Fuxiang Fan, Jingbo Du, Yanbo Lou
期刊:Tropical Journal Of Pharmaceutical Research
影响因子 :0.600