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产品概述
| 名称 | HOS (人骨肉瘤细胞)(STR鉴定正确） |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 成纤维细胞、上皮细胞样 |
| 生长培养基 | MEM（含NEAA）＋10% FBS＋1% P/S |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 背景描述 | HOS细胞是从一名13岁的白人女性的骨肉瘤组织中分离建立的；HOS细胞表现为扁平形态、低饱和密度、软琼脂中的低克隆形成率和对化合物及病毒感染的敏感性。 |
| 年龄（性别） | 女；13岁 |
| 组织来源 | 骨；骨肉瘤 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肉瘤细胞 |
| 生物安全等级 | 1 |
| 保藏机构 | ATCC; CRL-1543 ECACC; 87070202 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 24,25 D3S1358 15 D5S818 13 D7S820 11,12 D8S1179 14 D13S317 12 D16S539 10,13 D18S51 14 D19S433 13 D21S11 31.2,32.2 FGA 24 PentaD 9,10 PentaE 7,12 TH01 6 TPOX 8,11 vWA 18 D6S1043 18 D12S391 20 D2S441 10 -
STR鉴定图
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参考文献
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A novel photothermally controlled multifunctional scaffold for clinical treatment of osteosarcoma and tissue regeneration(2020/06/01)
作者：Liang Ma, Xiaobo Feng, Hang Liang
期刊：Materials Today
DOI：10.1016/j.mattod.2019.12.005
影响因子 ：26.943
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lncRNA MELTF-AS1 facilitates osteosarcoma metastasis by modulating MMP14 expression(2021/08/26)
作者：Lei Ding, Taiyuan Liu, Yuan Qu
期刊：Molecular Therapy-Nucleic Acids
DOI：10.1016/j.omtn.2021.08.022
影响因子 ：10.183
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Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells(2021/10/18)
作者：Yi Luo, Xu Gao, Luetao Zou
期刊：Oxidative Medicine and Cellular Longevity
影响因子 ：7.310
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Ten-gene signature reveals the significance of clinical prognosis and immuno-correlation of osteosarcoma and study on novel skeleton inhibitors regarding MMP9(2021/07/14)
作者：Weihang Li, Ziyi Ding, Dong Wang
期刊：Cancer Cell International
DOI：10.1186/s12935-021-02041-4
影响因子 ：6.429
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ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p(2020/03/30)
作者：Quan Yuan, Honghao Yu, Jianhua Chen
期刊：Cancer Cell International
DOI：10.1186/s12935-020-01174-2
影响因子 ：6.429
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Sirt1 modulates H3 phosphorylation and facilitates osteosarcoma cell autophagy(2019/08/07)
作者：Hongliang Ying, Boda Ying, Jinrui Zhang
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1648280
影响因子 ：6.355
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Anoikis patterns exhibit distinct prognostic and immune landscapes in Osteosarcoma(2023/01/09)
作者：Zhao Zhang, Zhijie Zhu, Jun Fu
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.109684
影响因子 ：5.7140
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Hsa_circ_0097271 Knockdown Attenuates Osteosarcoma Progression via Regulating miR-640/MCAM Pathway(2022/10/26)
作者：Peng Sun, Xuan Yang
期刊：DISEASE MARKERS
影响因子 ：3.4640
引用产品：CL-0360
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Farnesyl diphosphate synthase promotes cell proliferation by regulating gene expression and alternative splicing profiles in HeLa cells(2023/02/28)
作者：Lijuan Wang, Zhigang Chen, Dong Chen
期刊：Oncology Letters
影响因子 ：3.1110
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Hsa_circ_0000591 drives osteosarcoma glycolysis and progression by sequestering miR-194-5p and elevating HK2 expression(2023/02/21)
作者：Dawei Wang, Yang Wang, Huadong Wang
期刊：CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
影响因子 ：2.9630
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A New 7-azaindole Structure Analog: Molecular Docking, Synthesis and Preliminary Biological Activity in vitro for Anticancer(2022/09/09)
作者：Yifeng Zhan, Hang Tong, Shibo He
期刊：CHEMISTRY & BIODIVERSITY
影响因子 ：2.7450
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Circ_0003732 promotes osteosarcoma progression through regulating miR-377-3p/CPEB1 axis and Wnt/β-catenin signaling pathway(2022/01/01)
作者：Zheng Zhou, Tang Liu, Zhihong Li
期刊：Anti-Cancer Drugs
DOI：10.1097/CAD.0000000000001206
影响因子 ：2.3890
