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产品概述
| 名称 | HCCLM3 (人高转移肝癌细胞)(暂不出售） |
| 别称 | LM3; MHCC-LM3; MHCCLM3 |
| 背景描述 | HCCLM3细胞是一株由人肝癌细胞株MHCC97-H接种裸鼠、进行3次肺转移筛选、取肺转移瘤建成皮下接种后高度自发性肺转移的肝癌细胞系。HCCLM3细胞被广泛用于人肝癌发病机理的基础和临床研究，也可用于抗肿瘤药物筛选。 |
| 种属 | 人 |
| 年龄（性别） | 39岁 |
| 组织来源 | 肝；肝癌 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肝胆癌细胞 |
| 生长培养基 | DMEM＋10% FBS＋1% P/S |
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 倍增时间 | ~35-48 hours |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
参考文献
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lncRNA PRR34-AS1 promotes HCC development via modulating Wnt/β-catenin pathway by absorbing miR-296-5p and upregulating E2F2 and SOX12(2021/04/24)
作者：Minzhen Qin, Yiliang Meng, Chunying Luo
期刊：Molecular Therapy-Nucleic Acids
DOI：10.1016/j.omtn.2021.04.016
影响因子 ：10.183
引用产品：CL-0278
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The long noncoding RNA TINCR promotes self-renewal of human liver cancer stem cells through autophagy activation(2022/11/16)
作者：Shi, Jing, Guo, Cao, Li, Yang, Ma, Junli
期刊：Cell Death & Disease
DOI：10.1038/s41419-022-05424-1
影响因子 ：9.6850
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HIF1A activates the transcription of lncRNA RAET1K to modulate hypoxia-induced glycolysis in hepatocellular carcinoma cells via miR-100-5p(2020/03/09)
作者：Yufan Zhou, Yun Huang, Kuan Hu
期刊：Cell Death & Disease
影响因子 ：9.685
引用产品：CL-0278
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LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway(2021/11/27)
作者：Ying Xing,Yang Liu，Zhong Qi
期刊：Cellular & Molecular Biology Letters
DOI：10.1186/s11658-021-00295-4
影响因子 ：8.7020
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CircWHSC1 serves as an oncogene to promote hepatocellular carcinoma progression(2021/04/27)
作者：Pengfei Lyu, Zhensheng Zhai, Zhengwen Hao
期刊：European Journal Of Clinical Investigation
影响因子 ：5.722
引用产品：CL-0278
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CCAT2 enhances autophagy-related invasion and metastasis via regulating miR-4496 and ELAVL1 in hepatocellular carcinoma(2021/08/24)
作者：Jing Shi, Cao Guo, Junli Ma
期刊：Journal Of Cellular And Molecular Medicine
影响因子 ：5.295
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ZSCAN16-AS1 expedites hepatocellular carcinoma progression via modulating the miR-181c-5p/SPAG9 axis to activate the JNK pathway(2021/06/07)
作者：Jianwen Liu, Ruiqing Liu, Yuyan Liu
期刊：Cell Cycle
DOI：10.1080/15384101.2021.1919828
影响因子 ：5.173
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AC093797.1 as a Potential Biomarker to Indicate the Prognosis of Hepatocellular Carcinoma and Inhibits Cell Proliferation, Invasion, and Migration by Reprogramming Cell Metabolism and Extracellular Matrix Dynamics(2021/12/03)
作者：Xiaoling Liu, Chenyu Wang, Qing Yang
期刊：Frontiers in Genetics
影响因子 ：4.7720
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circ-PRKCI targets miR-1294 and miR-186-5p by downregulating FOXK1 expression to suppress glycolysis in hepatocellular carcinoma(2021/4/21)
作者：Wenqi Chen, Yuehua Li, Jing Zhong
期刊：Molecular Medicine Reports
影响因子 ：3.4230
引用产品：CL-0278
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LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma(2020/05/21)
作者：Wei Zhang, Lei Han, Peng Xing
期刊：Naunyn-Schmiedebergs Archives of Pharmacology
DOI：10.1007/s00210-020-01889-z
影响因子 ：3.1950
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Curcumin Inhibits Hepatocellular Carcinoma via Regulating miR-21/TIMP3 Axis(2020/07/17)
作者：Jingtao Li, Hailiang Wei, Yonggang Liu
期刊：Evidence-Based Complementary and Alternative Medicine
影响因子 ：2.6500
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LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma(2020/05/21)
作者：Wei Zhang, Lei Han, Peng Xing
期刊：Naunyn-Schmiedebergs Archives of Pharmacology
DOI：10.1007/s00210-020-01889-z
影响因子 ：2.0500
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CXCL14 inhibits the growth and promotes apoptosis of hepatocellular carcinoma cells via suppressing Akt/mTOR pathway(2020/10/27)
作者：Jianqiang Bi, Quanle Liu, Yunchuan Sun
期刊：Journal Of Receptors And Signal Transduction
DOI：10.1080/10799893.2020.1837870
影响因子 ：0.0000
