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产品概述
名称 | HCCLM3 (人高转移肝癌细胞)(暂不出售) |
别称 | LM3; MHCC-LM3; MHCCLM3 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
生长培养基 | DMEM+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | HCCLM3细胞是一株由人肝癌细胞株MHCC97-H接种裸鼠、进行3次肺转移筛选、取肺转移瘤建成皮下接种后高度自发性肺转移的肝癌细胞系。HCCLM3细胞被广泛用于人肝癌发病机理的基础和临床研究,也可用于抗肿瘤药物筛选。 |
年龄(性别) | 39岁 |
组织来源 | 肝;肝癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肝胆癌细胞 |
倍增时间 | ~35-48 hours |
参考文献
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The long noncoding RNA TINCR promotes self-renewal of human liver cancer stem cells through autophagy activation(2022/11/16)
作者:Shi, Jing, Guo, Cao, Li, Yang, Ma, Junli
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-05424-1
影响因子 :9.000
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HIF1A activates the transcription of lncRNA RAET1K to modulate hypoxia-induced glycolysis in hepatocellular carcinoma cells via miR-100-5p(2020/03/09)
作者:Yufan Zhou, Yun Huang, Kuan Hu
期刊:Cell Death & Disease
影响因子 :9.000
引用产品:CL-0278
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USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilization(2023/06/13)
作者:Jianing Tang, Guo Long, Liang Xiao
期刊:Cell Death & Disease
DOI:10.1038/s41419-023-05747-7
影响因子 :9.000
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lncRNA PRR34-AS1 promotes HCC development via modulating Wnt/β-catenin pathway by absorbing miR-296-5p and upregulating E2F2 and SOX12(2021/04/24)
作者:Minzhen Qin, Yiliang Meng, Chunying Luo
期刊:Molecular Therapy-Nucleic Acids
DOI:10.1016/j.omtn.2021.04.016
影响因子 :8.800
引用产品:CL-0278
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LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway(2021/11/27)
作者:Ying Xing,Yang Liu,Zhong Qi
期刊:Cellular & Molecular Biology Letters
DOI:10.1186/s11658-021-00295-4
影响因子 :8.300
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Overcoming the resistance of hepatocellular carcinoma to PD-1/PD-L1 inhibitor and the resultant immunosuppression by CD38 siRNA-loaded extracellular vesicles(2022/12/26)
作者:Jun Deng, Hui Ke
期刊:OncoImmunology
DOI:10.1080/2162402X.2022.2152635
影响因子 :7.200
引用产品:CL-0120 CL-0278 CL-0323 CL-0497 CP-M131 PB180323 PM150110 PM150210
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CircWHSC1 serves as an oncogene to promote hepatocellular carcinoma progression(2021/04/27)
作者:Pengfei Lyu, Zhensheng Zhai, Zhengwen Hao
期刊:European Journal Of Clinical Investigation
影响因子 :5.500
引用产品:CL-0278
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CCAT2 enhances autophagy-related invasion and metastasis via regulating miR-4496 and ELAVL1 in hepatocellular carcinoma(2021/08/24)
作者:Jing Shi, Cao Guo, Junli Ma
期刊:Journal Of Cellular And Molecular Medicine
影响因子 :5.300
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Circ_0007429/miR-637/TRIM71/Ago2 axis participates in the regulation of proliferation, migration, invasion, apoptosis, and aerobic glycolysis of HCC(2023/03/15)
作者:Lilan Fan, Panpan Xia, Jing Wang
期刊:MOLECULAR CARCINOGENESIS
DOI:10.1002/mc.23526
影响因子 :4.600
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Comprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma(2023/04/20)
作者:Bowen Li, Jinghang Liu, Liangzhi Xu
期刊:Journal of Inflammation Research
影响因子 :4.500
引用产品:CL-0278
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Ultrasound-Targeted Microbubble Destruction-Mediated Downregulation of EZH2 Inhibits Stemness and Epithelial-Mesenchymal Transition of Liver Cancer Stem Cells(2021/01/11)
作者:Jie Wu, Lulu Sun, Tingting Liu
期刊:OncoTargets and Therapy
影响因子 :4.345
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ZSCAN16-AS1 expedites hepatocellular carcinoma progression via modulating the miR-181c-5p/SPAG9 axis to activate the JNK pathway(2021/06/07)
作者:Jianwen Liu, Ruiqing Liu, Yuyan Liu
期刊:Cell Cycle
DOI:10.1080/15384101.2021.1919828
影响因子 :4.300
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Circular RNA circBNC2 facilitates glycolysis and stemness of hepatocellular carcinoma through the miR-217/high mobility group AT-hook 2 (HMGA2) axis.(2023/06/09)
作者:Yan Feng, Shufeng Xia, Junlan Hui
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e17120
影响因子 :4.000
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AC093797.1 as a Potential Biomarker to Indicate the Prognosis of Hepatocellular Carcinoma and Inhibits Cell Proliferation, Invasion, and Migration by Reprogramming Cell Metabolism and Extracellular Matrix Dynamics(2021/12/03)
作者:Xiaoling Liu, Chenyu Wang, Qing Yang
期刊:Frontiers in Genetics
影响因子 :3.700
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LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma(2020/05/21)
作者:Wei Zhang, Lei Han, Peng Xing
期刊:Naunyn-Schmiedebergs Archives of Pharmacology
DOI:10.1007/s00210-020-01889-z
影响因子 :3.600
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LncRNA RHPN1-AS1 accelerates proliferation, migration, and invasion via regulating miR-485-5p/BSG axis in hepatocellular carcinoma(2020/05/21)
作者:Wei Zhang, Lei Han, Peng Xing
期刊:Naunyn-Schmiedebergs Archives of Pharmacology
DOI:10.1007/s00210-020-01889-z
影响因子 :3.600
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BTF3 promotes proliferation and glycolysis in hepatocellular carcinoma by regulating GLUT1(2023/06/29)
作者:Peng Wang, Jianmin Sun, Chengming Sun
期刊:CANCER BIOLOGY & THERAPY
DOI:10.1080/15384047.2023.2225884
影响因子 :3.600
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circ-PRKCI targets miR-1294 and miR-186-5p by downregulating FOXK1 expression to suppress glycolysis in hepatocellular carcinoma(2021/4/21)
作者:Wenqi Chen, Yuehua Li, Jing Zhong
期刊:Molecular Medicine Reports
影响因子 :3.400
引用产品:CL-0278
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CXCL14 inhibits the growth and promotes apoptosis of hepatocellular carcinoma cells via suppressing Akt/mTOR pathway(2020/10/27)
作者:Jianqiang Bi, Quanle Liu, Yunchuan Sun
期刊:Journal Of Receptors And Signal Transduction
DOI:10.1080/10799893.2020.1837870
影响因子 :2.800
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Curcumin Inhibits Hepatocellular Carcinoma via Regulating miR-21/TIMP3 Axis(2020/07/17)
作者:Jingtao Li, Hailiang Wei, Yonggang Liu
期刊:Evidence-Based Complementary and Alternative Medicine
影响因子 :2.650