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产品概述
名称 | NCI-H1975 (人肺腺癌细胞) (STR鉴定正确) |
别称 | H1975; H-1975 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
生长培养基 | RPMI-1640+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | NCI-H1975细胞是于1988年7月从一名女性(无抽烟史)非小细胞肺腺癌组织中分离得到的。 |
年龄(性别) | 女 |
组织来源 | 器官:肺;疾病:腺癌;非小细胞肺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肺癌细胞 |
生物安全等级 | 1 |
倍增时间 | ~28-45 hours |
保藏机构 | ATCC; CRL-5908 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 17 D3S1358 14,15 D5S818 11,12 D7S820 8,11 D8S1179 13,16 D13S317 10,13 D16S539 9,12 D18S51 13 D19S433 15,15.2 D21S11 28 FGA 21,24 PentaD 12,13 PentaE 12,16 TH01 7 TPOX 8,11 vWA 18 D6S1043 12 D12S391 17 D2S441 10,11 -
STR鉴定图
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参考文献
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Thioredoxin reductase 1 inhibitor shikonin promotes cell necroptosis via SecTRAPs generation and oxygen-coupled redox cycling(2021/12/30)
作者:Yue Zhang, Shibo Sun, Weiping Xu
期刊:Free Radical Biology And Medicine
DOI:10.1016/j.freeradbiomed.2021.12.314
影响因子 :8.101
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LncRNA CCAT2 promotes tumorigenesis by over-expressed Pokemon in non-small cell lung cancer(2017/01/12)
作者:Zhihong Zhao, Ju Wang, Shengfa Wang
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2016.12.122
影响因子 :7.500
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Plumbagin reduction by thioredoxin reductase 1 possesses synergy effects with GLUT1 inhibitor on KEAP1-mutant NSCLC cells(2021/12/23)
作者:Shibo Sun, Yue Zhang, Weiping Xu
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2021.112546
影响因子 :7.419
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Erianin inhibits human lung cancer cell growth via PI3K/Akt/mTOR pathway in vitro and in vivo(2021/03/17)
作者:Huiqiong Zhang, Xiaofang Xie, Gangmin Li
期刊:Phytotherapy Research
DOI:10.1002/ptr.7154
影响因子 :7.200
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Tumor-suppressive E3 ubiquitin ligase CHIP inhibits the PBK/ERK axis to repress stem cell properties and radioresistance in non-small cell lung cancer(2022/11/27)
作者:Tan, Bo, Zhang, Jingwei, Wang, Wen, Ma, Haibo, Yang, Yuanyuan
期刊:APOPTOSIS
DOI:10.1007/s10495-022-01789-y
影响因子 :7.200
引用产品:CL-0016 CL-0165 CL-0298 CL-0496 CL-0668 CM-0496 PCK001 PM150110
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Novel 4-anilinoquinazoline derivatives featuring an 1-adamantylmoiety as potent EGFR inhibitors with enhanced activity againstNSCLC cell lines(2016/01/26)
作者:Haiqing Yu, Yanxia Li, Yang Ge
期刊:European Journal of Medicinal Chemistry
DOI:DOI: 10.1016/j.ejmech.2016.01.045
影响因子 :6.700
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Long noncoding RNA FBXL19‐AS1 induces tumor growth and metastasis by sponging miR‐203a‐3p in lung adenocarcinoma(2019/09/20)
作者:Liming Wang, Xin Zhang, Yang Liu
期刊:Journal of Cellular Physiology
影响因子 :5.600
引用产品:CL-0298
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C1GALT1, Negatively Regulated by miR-181d-5p, Promotes Tumor Progression via Upregulating RAC1 in Lung Adenocarcinoma(2021/070/7)
作者:Xiaoxia Dong, Yongyu Liu, Xinzhou Deng
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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Prognostic Value of Genomic Instability of m 6 A-Related lncRNAs in Lung Adenocarcinoma(2022/03/03)
作者:Rui Li, JianPing Li, TingTing Liu
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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Inhibition effect of oxyepiberberine isolated from Coptis chinensis franch. On non-small cell lung cancer based on a network pharmacology approach and experimental validation(2021/6/1)
作者:Ying Zhang, Yunfeng Yao, Yingjie Fu
期刊:Journal Of Ethnopharmacology
影响因子 :5.400
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Structurally Diverse Diterpenes from the South China Sea Soft Coral Sarcophyton trocheliophorum(2023/01/20)
作者:Yuting Song, Dandan Yu, Mingzhi Su
期刊:Marine Drugs
影响因子 :5.400
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Exosomal Delivery of FTO Confers Gefitinib Resistance to Recipient Cells through ABCC10 Regulation in an m6A-dependent Manner(2021/02/09)
作者:Peng Xiao, Yukang Liu, Wei Han
期刊:Molecular Cancer Research
DOI:10.1158/1541-7786.MCR-20-0541
影响因子 :5.200
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Long non-coding RNA FAM83A antisense RNA 1 (lncRNA FAM83A-AS1) targets microRNA-141-3p to regulate lung adenocarcinoma cell proliferation, migration, invasion, and epithelial-mesenchymal transition progression(2022/02/14)
作者:Hongyu Huang, Chuyi Yang, Qichen Zhang
期刊:Bioengineered
DOI:10.1080/21655979.2022.2037871
影响因子 :4.900
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GRIN2D knockdown suppresses the progression of lung adenocarcinoma by regulating the E2F signalling pathway(2023/04/19)
作者:Zhitao Chen, Yanhui Song, Peipei Li
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2023.110685
影响因子 :4.800
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LncRNA surfactant associated 1 activates large tumor suppressor kinase 1/Yes-associated protein pathway via modulating hypoxic exosome-delivered miR-4766–5p to inhibit lung adenocarcinoma metastasis(2022/10/22)
作者:Weiqiang Zhang, Miaochun Bai, Keqiang Liu
期刊:INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI:10.1016/j.biocel.2022.106317
影响因子 :4.000
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SLC7A5 is a lung adenocarcinoma-specific prognostic biomarker and participates in forming immunosuppressive tumor microenvironment(2022/10/02)
作者:Yong Liu, Guoyuan Ma, Jichang Liu
期刊:Heliyon
DOI:10.1016/j.heliyon.2022.e10866
影响因子 :4.000
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TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT(2021/11/7)
作者:Danjie Zhang, Liangzhang Sun, Jin Zhang
期刊:Toxicology And Applied Pharmacology
DOI:10.1016/j.taap.2021.115793
影响因子 :3.800
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RNA editing enzyme adenosine deaminases acting on RNA 1 deficiency increases the sensitivity of non-small cell lung cancer cells to anlotinib by regulating CX3CR1-fractalkine expression(2021/07/28)
作者:Min Wu, Mengmeng Jin, Xiaohui Cao
期刊:Drug Development Research
影响因子 :3.800
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Comprehensive analysis of an immune infiltrate-related competitive endogenous RNA network reveals potential prognostic biomarkers for non-small cell lung cancer(2021/12/02)
作者:Caizhi Yang, Leihao Hu, Zhongyu Huang
期刊:PLoS One
DOI:10.1371/journal.pone.0260720
影响因子 :3.700
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SLC6A8 is involved in the progression of non-small cell lung cancer through the Notch signaling pathway(2020/10/27)
作者:Yan Feng, Xiangyu Guo, Huaping Tang
期刊:Annals of Translational Medicine
影响因子 :3.616
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Intelligent Genetic Decoding System Based on Nucleic Acid Isothermal Amplification for Non-Small Cell Lung Cancer Diagnosis(2023/03/12)
作者:Xiaonan Liu, Jiaxing Zhang, Kai Hua
期刊:Micromachines
影响因子 :3.400
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Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma(2023/02/24)
作者:Rui Chen, Zhiping Wang, Tianzhu Lu
期刊:Thoracic Cancer
影响因子 :2.900
引用产品:CL-0016 CL-0161 CL-0165 CL-0166 CL-0298 CL-0668 CM-0161
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Mechanism of Key Ingredient of Astragalus membranaceus on Lung Adenocarcinoma via PI3K/AKT Signaling Clarified by Utilizing Network Pharmacology Approach and Experimental Validation(2022/08/31)
作者:Yuanchun Wang, Jianrong Hui, Gang Xiao
期刊:Chinese Journal of Integrative Medicine
影响因子 :2.900
引用产品:CL-0298
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MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34(2023/06/13)
作者:Junhua Wu, Chongmei Yue, Weiguo Xu
期刊:Oncology Letters
影响因子 :2.900
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Calponin 3 suppresses proliferation, migration and invasion of non‑small cell lung cancer cells(2021/7/1)
作者:Chenglin Yang, Shiping Zhu, Weifeng Feng
期刊:Oncology Letters
影响因子 :2.900
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Anti-tumor cembrane diterpenoids from the South China Sea soft coral Lobophytum sp.(2023/02/28)
作者:Fan Yang, Yuting Song, Dandan Yu
期刊:CHEMISTRY & BIODIVERSITY
影响因子 :2.900
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Long noncoding RNA LINC00968 inhibits proliferation, migration and invasion of lung adenocarcinoma through targeting miR-22-5p/CDC14A axis(2021/09/14)
作者:Chao Wu, Xuzhao Bian, Liyuan Zhang
期刊:3 BIOTECH
DOI:10.1007/s13205-021-02981-8
影响因子 :2.893
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Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p(2020/01/10)
作者:Runa Dao, Muli Wudu, Linping Hui
期刊:Pathology Research and Practice
影响因子 :2.800
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LncRNA PCAT6 promotes proliferation, migration, invasion, and epithelial-mesenchymal transition of lung adenocarcinoma cell by targeting miR-545-3p(2023/02/14)
作者:Chuyi Yang, Hongyu Huang, Yongpeng Li
期刊:MOLECULAR BIOLOGY REPORTS
DOI:10.1007/s11033-023-08259-x
影响因子 :2.800
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Anticancer roles of let‑7f‑1‑3p in non‑small cell lung cancer via direct targeting of integrin β1(2021/9/16)
作者:Yanan Yang, Yuanrong Liu,Ning Xie
期刊:Experimental and Therapeutic Medicine
影响因子 :2.700
引用产品:CL-0298
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Dysregulated expression of microRNA involved in resistance to osimertinib in EGFR mutant non-small cell lung cancer cells(2023/04/24)
作者:Dianbao Zhang, Yukun Yang, Yixin Kang
期刊:Journal of Thoracic Disease
影响因子 :2.500
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Circular RNA Circ_0005962 Contributes to Lung Adenocarcinoma Cell Proliferation and Stem Cell Formation Through Sponging of miR-3611 and Modulating CYP24A1 Expression(2022/12/21)
作者:Wenjing Lu, Zhigao Yu, Jun Liu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10312-6
影响因子 :2.400
引用产品:164210-50 CL-0016 CL-0094 CL-0298 CL-0496 CM-0016 CM-0094 CM-0298 CM-0496 PB180120 PM150110 PM150210 PM150910