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  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)

H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)

货号:CL-0089

规格:1×10⁶cells/T25培养瓶

价格: ¥1600

生长培养基:DMEM10% FBS1% P/S

数量: - +

  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
  • H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)

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产品概述
产品信息
名称 H9c2(2-1) (大鼠心肌细胞) (种属鉴定正确)
别称 H9c2 (2-1); H9c2; H9C2
种属 大鼠
生长特性 贴壁细胞
细胞形态 成肌细胞样
冻存条件 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮
培养方案A(默认)
生长培养基:
培养条件:
气相:空气,95%;CO2,5%, 温度:37℃
推荐传代比例 1:2-1:4
推荐换液频率 2-3次/周
参考资料(来源文献)
背景描述 H9c2(2-1)细胞是一株由Kimes·B和Brandt·B从BD1X大鼠胚胎心脏组织的克隆细胞株亚克隆得到的细胞株;H9c2(2-1)细胞表现出许多骨骼肌的特性。H9c2(2-1)细胞中的成肌细胞能融合形成多核的肌管,并对乙酰胆碱的刺激发生反应。如果培养基中的血清浓度下降到1%,H9c2(2-1)细胞融合发生得很快。
年龄(性别) 胚胎
组织来源 心脏,心肌层
细胞类型 自发永生化细胞
生物安全等级 BSL-1
受体表达情况 acetylcholine, expressed
基因表达情况 myokinase; creatine phosphokinase; myosin
保藏机构 ATCC; CRL-1446 BCRC; 60096 BCRJ; 0098 ECACC; 88092904
种属鉴定
  • 种属鉴定图
参考文献
文献列表
  • Bioenergetic Metabolism Modulatory Peptide Hydrogel for Cardiac Protection and Repair After Myocardial Infarction(2024/01/12)

    作者:Yushan Zhang, Yu Gao, Jingrong Wang

    期刊:ADVANCED FUNCTIONAL MATERIALS

    DOI:10.1002/adfm.202312772

    影响因子 :19.000

    引用产品:CL-0089

  • Nb2CTx MXene coating with inhibition of oxidative stress prepared by Marangoni effect for hemodialysis therapy(2024/02/27)

    作者:Yang He, Hanshu Sun, Yanjie Wang

    期刊:CHEMICAL ENGINEERING JOURNAL

    DOI:10.1016/j.cej.2024.150047

    影响因子 :15.100

    引用产品:CL-0089

  • Xinshuaining preparation protects H9c2 cells from H2O2-induced oxidative damage through the PI3K/Akt/Nrf-2 signaling pathway(2022/10/20)

    作者:Mingjun Han, Jie Lin, Yi Yang

    期刊:CLINICAL AND EXPERIMENTAL HYPERTENSION

    DOI:10.1080/10641963.2022.2131806

    影响因子 :12.300

    引用产品:CL-0089

  • A Highly Sensitive Strategy for Fluorescence Imaging of MicroRNA in Living Cells and in Vivo Based on Graphene Oxide-Enhanced Signal Molecules Quenching of Molecular Beacon(2018/02/15)

    作者:Limin Yang, Bo Liu, Meimei Wang

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.7b19284

    影响因子 :9.500

    引用产品:CL-0089 CL-0101 CL-0103 CL-0149

  • Framework Nucleic Acid-Based Multifunctional Tumor Theranostic Nanosystem for miRNA Fluorescence Imaging and Chemo/Gene Therapy(2023/07/08)

    作者:Haikun Luo, Zhao Wang, Qian Mo

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.3c01611

    影响因子 :9.500

    引用产品:CL-0089 CL-0103

  • Triphenyl phosphate induces cardiotoxicity through myocardial fibrosis mediated by apoptosis and mitophagy of cardiomyocyte in mice(2024/02/24)

    作者:Feibo Xu, Yu He, Aili Xu

    期刊:ENVIRONMENTAL POLLUTION

    DOI:10.1016/j.envpol.2024.123651

    影响因子 :8.900

    引用产品:CL-0089

  • Sinapine Targeting PLCβ3 EF Hands Disrupts Gαq-PLCβ3 Interaction and Ameliorates Cardiovascular Diseases(2023/11/15)

    作者:Simeng Chu, Fukui Shen, Wenjuan Liu

    期刊:PHYTOMEDICINE

    DOI:10.1016/j.phymed.2023.155200

    影响因子 :7.900

    引用产品:CL-0089

  • Ramelteon alleviates myocardial ischemia/reperfusion injury (MIRI) through Sirt3-­dependent regulation of cardiomyocyte apoptosis(2024/02/07)

    作者:Zhenbo Yang, Yilin Xie, Mengyang Li

    期刊:BIOMEDICINE & PHARMACOTHERAPY

    DOI:10.1016/j.biopha.2024.116229

    影响因子 :7.500

    引用产品:CL-0089

  • Phloretin ameliorates heart function after myocardial infarction via NLRP3/Caspase-1/IL-1β signaling(2023/07/04)

    作者:Bin Li, Liao Xu, Jiangwen Liu

    期刊:BIOMEDICINE & PHARMACOTHERAPY

    DOI:10.1016/j.biopha.2023.115083

    影响因子 :7.500

    引用产品:CL-0089

  • Myocardial protection properties of parishins from the roots of Gastrodia elata Bl(2019/11/15)

    作者:Qi Wang, Zhifeng Li, Dongxu Wang

    期刊:Biomedicine & Pharmacotherapy

    DOI:10.1016/j.biopha.2019.109645

    影响因子 :7.500

    引用产品:CL-0089

  • Fluorescent Nanocomposite for Visualizing Cross-Talk between MicroRNA-21 and Hydrogen Peroxide in Ischemia-Reperfusion Injury in Live Cells and In Vivo(2016/11/02)

    作者:Limin Yang, Yanfei Ren, Wei Pan

    期刊:analytical chemistry

    DOI:10.1021/acs.analchem.6b03701

    影响因子 :7.400

    引用产品:CL-0089

  • SIRT1 regulates mitochondrial fission to alleviate high altitude hypoxia inducedcardiac dysfunction in rats via the PGC-1α-DRP1/FIS1/MFF pathway(2024/04/27)

    作者:Hongbao Xu, Xiaona Song, Xiaoru Zhang

    期刊:APOPTOSIS

    DOI:10.1007/s10495-024-01954-5

    影响因子 :7.200

    引用产品:CL-0089

  • Tanshinone IIA alleviates acute ethanol-induced myocardial apoptosis mainly through inhibiting the expression of PDCD4 and activating the PI3K/Akt pathway(2021/03/09)

    作者:Hanyu Deng, Bo Yu, Yang Li

    期刊:Phytotherapy Research

    DOI:10.1002/ptr.7102

    影响因子 :7.200

    引用产品:CL-0089

  • Lotus Bee Pollen Extract Inhibits Isoproterenol-Induced Hypertrophy via JAK2/STAT3 Signaling Pathway in Rat H9c2 Cells(2022/12/30)

    作者:Shuo Han, Lifu Chen, Yi Zhang

    期刊:Antioxidants

    DOI:10.3390/antiox12010088

    影响因子 :7.000

    引用产品:CL-0089

  • Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4(2023/08/01)

    作者:Dingyan Zhou, Weizhe Liu, Juanjuan Zhang

    期刊:Cell Death Discovery

    DOI:10.1038/s41420-023-01563-2

    影响因子 :7.000

    引用产品:CL-0089

  • Toxic effects of bisphenol S on mice heart and human umbilical cord endothelial cells(2023/11/02)

    作者:Hanlin Luo, Yang Yang, Hongyu Zhang

    期刊:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

    DOI:10.1016/j.ecoenv.2023.115652

    影响因子 :6.800

    引用产品:CL-0089

  • Macrophage membrane-modified targeted phase-change nanoparticles for multimodal imaging of experimental autoimmune myocarditis(2024/02/29)

    作者:Dan Yin, Min Zheng, Qin Zhang

    期刊:Nanoscale

    DOI:10.1039/D3NR05391A

    影响因子 :6.700

    引用产品:CL-0089

  • Bilobalide protects H9c2 cell from oxygen-glucose-deprivation-caused damage through upregulation of miR-27a(2019/12/01)

    作者:Ailin Cao, Xiangting Li

    期刊:Artificial Cells Nanomedicine and Biotechnology

    DOI:PMID:31322008

    影响因子 :6.355

    引用产品:CL-0089

  • Integrative applications of network pharmacology and molecular docking: An herbal formula ameliorates H9c2 cells injury through pyroptosis(2022/03/28)

    作者:Zhongwen Qi, Zhipeng Yan, Yueyao Wang

    期刊:Journal of Ginseng Research

    DOI:10.1016/j.jgr.2022.03.003

    影响因子 :6.300

    引用产品:CL-0089

  • Cholesterol 25-hydroxylase prevents type 2 diabetes mellitus induced cardiomyopathy by alleviating cardiac lipotoxicity(2024/04/06)

    作者:Jialiang Zhang, Hao Zhou, Fan Lei

    期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

    DOI:10.1016/j.bbadis.2024.167158

    影响因子 :6.200

    引用产品:CL-0089

  • Meteorin-like (METRNL) attenuates hypertensive induced cardiac hypertrophy by inhibiting autophagy via activating BRCA2(2024/03/07)

    作者:Jun Li, Yinghui Hong, Yinsheng Zhong

    期刊:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

    DOI:10.1016/j.bbadis.2024.167113

    影响因子 :6.200

    引用产品:CL-0089

  • Plasma exosomes from patients with acute myocardial infarction alleviate myocardial injury by inhibiting ferroptosis through miR-26b-5p/SLC7A11 axis(2023/04/01)

    作者:Huili Li, Jiaxing Ding, Wei Liu

    期刊:Life Sciences

    DOI:10.1016/j.lfs.2023.121649

    影响因子 :6.100

    引用产品:CL-0089

  • Cardioprotective and anti-inflammatory effects of Caveolin 1 in experimental diabetic cardiomyopathy(2023/03/24)

    作者:Wenyan Gong, Qibin Jiao, Jinghua Yuan

    期刊:CLINICAL SCIENCE

    DOI:10.1042/CS20220874

    影响因子 :6.000

    引用产品:CL-0089

  • Long non-coding RNA UCA1 relieves cardiomyocytes H9c2 injury aroused by oxygen-glucose deprivation via declining miR-122(2019/08/21)

    作者:Zaiwei Zhang, Hu Li, Zhiyuan Cui

    期刊:Artificial Cells Nanomedicine and Biotechnology

    DOI:10.1080/21691401.2019.1652630

    影响因子 :5.800

    引用产品:164210 CL-0089 PM150210A PM150270

  • ATP5me alleviates high glucose-induced myocardial cell injury(2024/02/05)

    作者:Qingsha Hou, Fang Yan, Xiuling Li

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2024.111626

    影响因子 :5.600

    引用产品:CL-0089

  • Maresin1 ameliorates ventricular remodelling and arrhythmia in mice models of myocardial infarction via NRF2/HO-1 and TLR4/NF-kB signalling(2022/10/21)

    作者:Fengyuan Wang, Yang Gong, Tao Chen

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2022.109369

    影响因子 :5.600

    引用产品:CL-0089

  • Quercetin Attenuates Cardiac Hypertrophy by Inhibiting Mitochondrial Dysfunction Through SIRT3/PARP-1 Pathway(2021/10/28)

    作者:WenJing Chen, Yan Cheng, Wen Li

    期刊:Frontiers in Pharmacology

    DOI:10.3389/fphar.2021.739615

    影响因子 :5.600

    引用产品:164210 164210-50 CL-0089 PB180120 PM150210

  • Peficitinib ameliorates doxorubicin-induced cardiotoxicity by suppressing cellular senescence and enhances its antitumor activity(2023/07/12)

    作者:Hui Hua, Qi Zhao, Jing Xia

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2023.110630

    影响因子 :5.600

    引用产品:CL-0016 CL-0089 CL-0171

  • Ethanol extract of propolis alleviates diabetic cardiomyopathy via JAK2/STAT3 signaling pathway(2023/07/21)

    作者:Peiying Shi, Tianyu Du, Fei Meng

    期刊:Journal of Functional Foods

    DOI:10.1016/j.jff.2023.105688

    影响因子 :5.600

    引用产品:CL-0089

  • Clemastine Fumarate Protects Against Myocardial Ischemia Reperfusion Injury by Activating the TLR4/PI3K/Akt Signaling Pathway(2020/02/10)

    作者:Xiaoxiao Yuan, Zhaodong Juan, Rui Zhang

    期刊:Frontiers in Pharmacology

    DOI:10.3389/fphar.2020.00028

    影响因子 :5.600

    引用产品:CL-0089

  • DNA methyltransferase 1 (DNMT1) suppresses mitophagy and aggravates heart failure via the microRNA-152-3p/ETS1/RhoH axis(2022/02/11)

    作者:Zhuojun Deng, Jiaqi Yao, Na Xiao

    期刊:Laboratory Investigation

    DOI:10.1038/s41374-022-00740-8

    影响因子 :5.502

    引用产品:CL-0089

  • Discovery of the signal pathways and major bioactive compounds responsible for the anti-hypoxia effect of Chinese cordyceps(2021/5/24)

    作者:Hailin Long, Xuehong Qiu, Li Cao

    期刊:Journal Of Ethnopharmacology

    DOI:10.1016/j.jep.2021.114215

    影响因子 :5.400

    引用产品:CL-0089

  • Maternal androgen excess inhibits fetal cardiomyocytes proliferation through RB-mediated cell cycle arrest and induces cardiac hypertrophy in adulthood(2023/08/29)

    作者:Huo Y., Wang W., Zhang J.

    期刊:JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

    DOI:10.1007/s40618-023-02178-1

    影响因子 :5.400

    引用产品:CL-0089 PM150210A

  • Quercetin ameliorates ferroptosis of rat cardiomyocytes via activation of the SIRT1/p53/SLC7A11 signaling pathway to alleviate sepsis‑induced cardiomyopathy(2023/10/18)

    作者:Xin Lin, Xiaoxia Zhao, Qingfeng Chen

    期刊:INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

    DOI:10.3892/ijmm.2023.5319

    影响因子 :5.400

    引用产品:CL-0089

  • Jingfang Granule mitigates Coxsackievirus B3-induced myocardial damage by modulating mucolipin 1 expression(2023/11/10)

    作者:Bowen Sun, Lin Lin, Tian Yao

    期刊:JOURNAL OF ETHNOPHARMACOLOGY

    DOI:10.1016/j.jep.2023.117396

    影响因子 :5.400

    引用产品:CL-0089

  • Exploring the effective components of honey-processed licorice (Glycyrrhiza uralensis Fisch.) in attenuating Doxorubicin-induced myocardial cytotoxicity by combining network pharmacology and in vitro experiments(2024/04/09)

    作者:Peijun Sun, Huixian Chen, Xiaoyu Fan

    期刊:JOURNAL OF ETHNOPHARMACOLOGY

    DOI:10.1016/j.jep.2024.118178

    影响因子 :5.400

    引用产品:CL-0089

  • Sodium butyrate attenuates angiotensin II‐induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6‐dependent mechanism(2019/09/29)

    作者:Linlin Zhang, Mokan Deng, Aihua Lu

    期刊:Journal Of Cellular And Molecular Medicine

    DOI:10.1111/jcmm.14684

    影响因子 :5.300

    引用产品:CL-0089

  • Qishen Yiqi Drop Pill, a novel compound Chinese traditional medicine protects against high glucose‐induced injury in cardiomyocytes(2019/07/06)

    作者:Shouyan Zhang, Hao Wang, Lixia Li

    期刊:Journal Of Cellular And Molecular Medicine

    DOI:10.1111/jcmm.14527

    影响因子 :5.300

    引用产品:CL-0089

  • The Antioxidant and Anti-Inflammatory Effects of Flavonoids from Propolis via Nrf2 and NF-κB Pathways(2022/08/13)

    作者:Wenzhen Xu, Han Lu, Yuan Yuan

    期刊:Foods

    DOI:10.3390/foods11162439

    影响因子 :5.200

    引用产品:CL-0089

  • Synthesis and biological evaluation of lycoctonine derivatives with cardiotonic and calcium channels inhibitory activities(2024/03/16)

    作者:Jianzhu Wang, Xiangyu Li, Min Zhang

    期刊:BIOORGANIC CHEMISTRY

    DOI:10.1016/j.bioorg.2024.107297

    影响因子 :5.100

    引用产品:CL-0089

  • Kinsenoside mitigates myocardial ischemia/reperfusion-induced ferroptosis via activation of the Akt/Nrf2/HO-1 pathway(2023/08/10)

    作者:Rong Wang, Siwei Dong, Rui Xia

    期刊:EUROPEAN JOURNAL OF PHARMACOLOGY

    DOI:10.1016/j.ejphar.2023.175985

    影响因子 :5.000

    引用产品:CL-0089

  • Effect of sotagliflozin on ventricular arrhythmias in mice with myocardial infraction(2022/10/28)

    作者:Gong Yang, Kong Bin, Shuai Wei

    期刊:EUROPEAN JOURNAL OF PHARMACOLOGY

    DOI:10.1016/j.ejphar.2022.175357

    影响因子 :5.000

    引用产品:CL-0089

  • Ferroportin-mediated ferroptosis involved in new-onset atrial fibrillation with LPS-induced endotoxemia(2021/11/05)

    作者:Jin Fang, Bin Kong, Wei Shuai

    期刊:European Journal of Pharmacology

    DOI:10.1016/j.ejphar.2021.174622

    影响因子 :5.000

    引用产品:CL-0089

  • Berberine inhibits NLRP3 inflammasome activation by regulating mTOR/mtROS axis to alleviate diabetic cardiomyopathy(2023/12/12)

    作者:Changsheng Zhong, Yilin Xie, Huifang Wang

    期刊:EUROPEAN JOURNAL OF PHARMACOLOGY

    DOI:10.1016/j.ejphar.2023.176253

    影响因子 :5.000

    引用产品:CL-0089

  • MicroRNA-381-3p signatures as a diagnostic marker in patients with sepsis and modulates sepsis-steered cardiac damage and inflammation by binding HMGB1(2021/11/12)

    作者:Jian Liu, Yadong Yang, Rong Lu

    期刊:Bioengineered

    DOI:10.1080/21655979.2021.2006967

    影响因子 :4.900

    引用产品:CL-0089

  • Xinyang Tablet attenuates chronic hypoxia-induced right ventricular remodeling via inhibiting cardiomyocytes apoptosis(2022/12/05)

    作者:Anran Gao, Shuo Li, Xiaocui Tan

    期刊:Chinese Medicine

    DOI:10.1186/s13020-022-00689-2

    影响因子 :4.900

    引用产品:CL-0089

  • Propofol protects ardiomyocytes from doxorubicin-induced toxic injury by activating the nuclear factor erythroid 2-related factor 2/glutathione peroxidase 4 signaling pathways(2022/04/01)

    作者:Ziyun Lu, Zhiyi Liu, Bei Fang

    期刊:Bioengineered

    DOI:10.1080/21655979.2022.2036895

    影响因子 :4.900

    引用产品:CL-0089

  • Sevoflurane inhibits the apoptosis of hypoxia/reoxygenation-induced cardiomyocytes via regulating miR-27a-3p-mediated autophagy(2021/10/07)

    作者:Yang Zhang, Biming Zhan, Ying Hu

    期刊:Journal Of Pharmacy And Pharmacology

    DOI:10.1093/jpp/rgab111

    影响因子 :4.810

    引用产品:164210 CL-0089 PB180322 PM150210

  • 7,8,3′-Trihydroxyflavone prevents doxorubicin-induced cardiotoxicity and mitochondrial dysfunction via activating Akt signaling pathway in H9c2 cells(2023/10/12)

    作者:Jing Zhao, Huaqing Yu, Fengqin Ge

    期刊:CELLULAR SIGNALLING

    DOI:10.1016/j.cellsig.2023.110924

    影响因子 :4.800

    引用产品:CL-0089

  • Mechanism of Action of Flavonoids of Oxytropis falcata on the Alleviation of Myocardial Ischemia–Reperfusion Injury(2022/03/05)

    作者:Yang Guo, Benyin Zhang, Yanfeng Peng

    期刊:Molecules

    DOI:10.3390/molecules27051706

    影响因子 :4.600

    引用产品:CL-0089

  • Puerarin Attenuates High-Glucose and High-Lipid-Induced Inflammatory Injury in H9c2 Cardiomyocytes via CAV3 Protein Upregulation(2023/06/28)

    作者:YiFu Tian, CaiXia Zhou, XiaoYang Bu

    期刊:Journal of Inflammation Research

    DOI:10.2147/JIR.S408681

    影响因子 :4.500

    引用产品:CL-0089

  • Phenylacetyl glutamine (PAGln) enhances cardiomyocyte death after myocardial infarction through β1 adrenergic receptor(2023/12/02)

    作者:Hang Xu, Na Yang, Baoyan Wang

    期刊:ENVIRONMENTAL TOXICOLOGY

    DOI:10.1002/tox.24063

    影响因子 :4.500

    引用产品:CL-0089

  • Protective Effect of Lemon Peel Extract on Oxidative Stress in H9c2 Rat Heart Cell Injury(2021/05/14)

    作者:Jun Wang, Yulin Zhai, Mingguang Ou

    期刊:Drug Design Development and Therapy

    DOI:10.2147/DDDT.S304624

    影响因子 :4.319

    引用产品:CL-0089

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