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产品概述
| 名称 | Hep G2 (人肝癌细胞) (STR鉴定正确) |
| 别称 | HEP-G2; Hep G2; HEP G2; HepG2; HEPG2 |
| 种属 | 人类 |
| 年龄（性别） | 男性，15岁 |
| 组织来源 | 肝细胞癌 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 背景描述 | Hep G2细胞是来自15岁男性白人的组织；Hep G2细胞形态为上皮细胞样，模式染色体数为55；Hep G2细胞在免疫抑制小鼠中不致瘤。 |
| 生物安全等级 | 1 |
| 生长培养基 | MEM＋10% FBS＋1% P/S |
| 推荐传代比例 | 1:2-1:3 |
| 推荐换液频率 | 2~3次/周 |
| 倍增时间 | ~50-60小时 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 保藏机构 | ATCC; HB-8065 BCRC; 60025 BCRJ; 0103 DSMZ; ACC-180 ECACC; 85011430 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,11 D2S1338 19,20 D3S1358 15,16 D5S818 11,12 D7S820 10 D8S1179 15,16 D13S317 9,13 D16S539 12 D18S51 13,14 D19S433 15.2 D21S11 29,31 FGA 22,25 PentaD 9,13 PentaE 15,20 TH01 9 TPOX 8,9 vWA 17 D6S1043 13 D12S391 21,25 D2S441 11.3,14 -
STR鉴定图
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参考文献
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Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase(2021/8/5)
作者：Shao, Ximing, Ding, Zhihao, Zhou, Wenhua
期刊：Nature Nanotechnology
DOI：10.1038/s41565-021-00952-x
影响因子 ：39.213
引用产品：CL-0016 CL-0101 CL-0103 CL-0150A CL-0150B CL-0236 CL-0238
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ANGPTL8 negatively regulates NF-κB activation by facilitating selective autophagic degradation of IKKγ(2017/12/18)
作者：Yu Zhang, Xian Guo, Wanyao Yan
期刊：Nature Communications
DOI：10.1038/s41467-017-02355-w
影响因子 ：14.919
引用产品：CL-0103
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Photoelectrochemical cell enhanced by ternary heterostructured photoanode: Toward high-performance self-powered cathodic cytosensing(2019.07.15)
作者：Gao-Chao Fan, YanweiLu, HuanZhao
期刊：Biosensors and Bioelectronics
DOI：10.1016/j.bios.2019.04.063
影响因子 ：10.618
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Target-induced formation of multiple DNAzymes in solid-state nanochannels: Toward innovative photoelectrochemical probing of telomerase activity(2019.10.01)
作者：Gao-Chao Fan, Yanwei Lu, Linzheng Ma
期刊：Biosensors and Bioelectronics
DOI：10.1016/j.bios.2019.111564
影响因子 ：10.618
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Target-induced formation of multiple DNAzymes in solid-state nanochannels: Toward innovative photoelectrochemical probing of telomerase activity(2019/08/02)
作者：Gao-Chao Fan, Yanwei Lu, Linzheng Ma
期刊：Biosensors & Bioelectronics
DOI：10.1016/j.bios.2019.111564
影响因子 ：10.618
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Photoelectrochemical cell enhanced by ternary heterostructured photoanode: Toward high-performance self-powered cathodic cytosensing(2019/05/03)
作者：Gao-Chao Fan, Yanwei Lu, Huan Zhao
期刊：Biosensors & Bioelectronics
DOI：10.1016/j.bios.2019.04.063
影响因子 ：10.618
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MoS2 Quantum Dot@Polyaniline Inorganic–Organic Nanohybrids for in Vivo Dual-Modal Imaging Guided Synergistic Photothermal/Radiation Therapy(2016/9/7)
作者：Jinping Wang, Xiaoxiao Tan, Xiaojuan Pang
期刊：ACS Applied Materials & Interfaces
影响因子 ：9.228999999999999
引用产品：CL-0016 CL-0101 CL-0103 CL-0150A CL-0150B CL-0236 CL-0238
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The enantiomer-selective metabolism of hexabromocyclododecanes (HBCDs) by human HepG2 cells(2021/1/4)
作者：Xue-song Wang, Xiao Tan, Yan Zhang
期刊：Science Of The Total Environment
DOI：10.1016/j.scitotenv.2020.144430
影响因子 ：7.963
引用产品：CL-0103
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Deep learning based label-free small extracellular vesicles analyzer with light-sheet illumination differentiates normal and cancer liver cells(2021/08/20)
作者：Zhuo Wang, Shuanglian Wang, Gao Chen
期刊：Sensors And Actuators B-Chemical
影响因子 ：7.460
引用产品：CL-0103
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Multienzyme-Targeted Fluorescent Probe as a Biosensing Platform for Broad Detection of Pesticide Residues(2021/5/11)
作者：Wu-Yingzheng Guo, Yi-Xuan Fu, Shi-Yu Liu
期刊：Anal Chem
DOI：10.1021/acs.analchem.1c00553
影响因子 ：6.986
引用产品：CL-0103
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Dual drug delivery system of photothermal-sensitive carboxymethyl chitosan nanosphere for photothermal-chemotherapy(2020.11.15)
作者：Xianwu Liu, Zuyu He, YuChen, ChuangZhou
期刊：International Journal of Biological Macromolecules
DOI：10.1016/j.ijbiomac.2020.06.202
影响因子 ：6.953
引用产品：CL-0103
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Regorafenib-loaded poly (lactide-co-glycolide) microspheres designed to improve transarterial chemoembolization therapy for hepatocellular carcinoma(2020.01.19)
作者：Xiang Li, Guangwei He, Feng Su, Zhaoxing Chu
期刊：Asian Journal of Pharmaceutical Sciences
DOI：10.1016/j.ajps.2020.01.001
影响因子 ：6.598
引用产品：CL-0103
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DMEP induces mitochondrial damage regulated by inhibiting Nrf2 and SIRT1/PGC-1α signaling pathways in HepG2 cells(2021/06/30)
作者：Huan Liu, Siyu Zhu, Wenna Han
期刊：Ecotoxicology And Environmental Safety
DOI：10.1016/j.ecoenv.2021.112449
影响因子 ：6.291
引用产品：CL-0103
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Detecting lipid droplets polarity: Silicone-based unique fluorescent probe for cancer diagnosis in living cells(2020/12/29)
作者：Fengqing Gai, Yujing Zuo, Weiying Lin
期刊：Talanta
DOI：10.1016/j.talanta.2020.122059
影响因子 ：6.057
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Mesencephalic astrocyte-derived neurotrophic factor ameliorates steatosis in HepG2 cells by regulating hepatic lipid metabolism(2020.03.14)
作者：Miao He, Cong Wang, Xiao-Hong Long, Jia-Jia Peng, Dong-Fang Liu, Gang-Yi Yang, Michael D Jensen, and Li-Li Zhang
期刊：World J Gastroenterol
影响因子 ：5.742
引用产品：CL-0103
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Multiwalled carbon nanotubes co-delivering sorafenib and epidermal growth factor receptor siRNA enhanced tumor-suppressing effect on liver cancer(2021/1/13)
作者：Zhili Wen, Yuliang Feng, Youwen Hu
期刊：Aging-US
影响因子 ：5.682
引用产品：CL-0103
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Tanshinone I induces cell apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and by suppressing p53/DRAM-mediated autophagy in human hepatocellular carcinoma(2020.02.04)
作者：Xu Liu, JiKui Liu
期刊：Artificial Cells, Nanomedicine, and Biotechnology
DOI：10.1080/21691401.2019.1709862
影响因子 ：5.678
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The effects of carbon dots produced by the Maillard reaction on the HepG2 cell substance and energy metabolism(2020.07.22)
作者：Dongmei Li, Xiaokang Na, Haitao Wang
期刊：FOOD & FUNCTION
影响因子 ：5.396
引用产品：CL-0103
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CCAT2 enhances autophagy-related invasion and metastasis via regulating miR-4496 and ELAVL1 in hepatocellular carcinoma(2021/08/24)
作者：Jing Shi, Cao Guo, Junli Ma
期刊：Journal Of Cellular And Molecular Medicine
影响因子 ：5.31
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A two-photon excited red-emissive probe for imaging mitochondria with high fidelity and its application in monitoring mitochondrial depolarization via FRET(2019.02.13)
作者：Jie Sun, Minggang Tian, Weiying Lin
期刊：Analyst
影响因子 ：4.616
引用产品：CL-0103
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Aronia melanocarpa anthocyanin extracts are an effective regulator of suppressor of cytokine signaling 3-dependent insulin resistance in HepG2 and C2C12 cells(2020/10/28)
作者：Jing Chen, Jinyan Zhu, Xianjun Meng
期刊：Journal of Functional Foods
影响因子 ：4.451
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Novel Deoxyvasicinone–Donepezil Hybrids as Potential Multitarget Drug Candidates for Alzheimer’s Disease(2019/02/05)
作者：Hongtao Du, Xinlian Liu, Jusen Xie
期刊：ACS Chemical Neuroscience
DOI：10.1021/acschemneuro.8b00699
影响因子 ：4.418
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Regulation of insulin resistance by targeting the insulin‐like growth factor 1 receptor with microRNA‐122‐5p in hepatic cells(08 April 2019)
作者：Li Dong, Xiaoyu Hou, Fengsui Liu
期刊：Cell Biol Int
影响因子 ：3.612
引用产品：CL-0103
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Surface charge switchable and core cross-linked polyurethane micelles as a reduction-triggered drug delivery system for cancer therapy(2017.02.13)
作者：Chang Liu, Yayuan Guan, Yuling Su
期刊：RSC Adv
影响因子 ：3.361
引用产品：CL-0103
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Effects of compound Kushen injection on pathology and angiogenesis of tumor tissues(2018.12.21)
作者：Hongyan Wang, Haiyan Hu, Hua Rong, Xuwei Zhao
期刊：Oncology Letters
影响因子 ：2.967
引用产品：CL-0103
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Resveratrol-loaded PLGA nanoparticles: enhanced stability, solubility and bioactivity of resveratrol for non-alcoholic fatty liver disease therapy(2018.10.14)
作者：Shuqian Wan, Long Zhang, Yunyun Quan
期刊：Royal Society Open Science
影响因子 ：2.963
引用产品：CL-0103
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MicroRNA-124a contributes to glucocorticoid resistance in acute-on-chronic liver failure by negatively regulating glucocorticoid receptor alpha(2020.03)
作者：Xin Wang, Hongrui Xu, Yadong Wang
期刊：Annals of Hepatology
DOI：10.1016/j.aohep.2019.08.007
影响因子 ：2.400
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Amelioration of the lipogenesis, oxidative stress and apoptosis of hepatocytes by a novel proteoglycan from Ganoderma lucidum()
作者：Shilin Yuan, Yanna Pan, Zeng Zhang
期刊：BIOLOGICAL & PHARMACEUTICAL BULLETIN
影响因子 ：2.233
引用产品：CL-0103
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Systematic understanding of the potential targets and pharmacological mechanisms of acteoside by network pharmacology approach(2020.01.25)
作者：Yiliyasi Aisa, Kurexi Yunusi
期刊：Medicinal Chemistry Research
DOI：10.1007/s00044-020-02524-5
影响因子 ：1.965
引用产品：CL-0103
