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产品概述
名称 | HuH-7 (人肝癌细胞) (STR鉴定正确) |
别称 | HuH-7; HUH-7; HuH7; Huh7; HUH7; JTC-39; Japanese Tissue Culture-39 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
生长培养基 | DMEM+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | 据说,HuH-7细胞可产甲胎蛋白、胰酶α抗体、血浆铜蓝蛋白、纤维蛋白原、纤维粘连蛋白等。 |
年龄(性别) | 男 |
组织来源 | 肝;肝癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肝胆癌细胞 |
保藏机构 | CCLV; CCLV-RIE 1079 JCRB; JCRB0403 KCB; KCB 200970YJ KCLB; 60104 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11 D2S1338 19 D3S1358 15 D5S818 12 D7S820 11 D8S1179 14 D13S317 10,11 D16S539 10 D18S51 15 D19S433 13,14 D21S11 30 FGA 22,23 PentaD 12 PentaE 11 TH01 7 TPOX 8,11 vWA 16,18 D6S1043 13,15 D12S391 20,21 D2S441 12,14 -
STR鉴定图
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参考文献
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Lung cancer shapes commensal bacteria via exosome-like nanoparticles(2022/03/17)
作者:Jipeng Jianga, Jie Mei, Shasha Jiang
期刊:Nano Today
DOI:10.1016/j.nantod.2022.101451
影响因子 :18.962
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ncRNAs-mediated high expression of TICRR promotes tumor cell proliferation and migration and is correlated with poor prognosis and tumor immune infiltration of hepatocellular carcinoma(2022/09/19)
作者:Kejie He, Yangfan Zhang, Laiying Liang
期刊:Molecular Therapy-Nucleic Acids
DOI:10.1016/j.omtn.2022.09.007
影响因子 :8.800
-
LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathway(2021/11/27)
作者:Ying Xing,Yang Liu,Zhong Qi
期刊:Cellular & Molecular Biology Letters
DOI:10.1186/s11658-021-00295-4
影响因子 :8.300
-
Visualization system based on hierarchical targeting for diagnosis and treatment of hepatocellular carcinoma(2022/08/22)
作者:Shasha Shi, Huipu Li, Xi Zheng
期刊:Materials Today Bio
DOI:10.1016/j.mtbio.2022.100398
影响因子 :8.200
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5′-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor 4A-I(2023/03/28)
作者:Chengdong Wu, Dekai Liu, Lufei Zhang
期刊:Frontiers of Medicine
影响因子 :8.100
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Upregulation of UGT1A1 expression by ursolic acid and oleanolic acid via the inhibition of the PKC/NF-κB signaling pathway(2021/08/25)
作者:Li Yuan, Lingming Zhang, Na Yao
期刊:Phytomedicine
DOI:10.1016/j.phymed.2021.153726
影响因子 :7.900
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Panaxytriol upregulates CYP3A4 expression based on the interaction of PXR, CAR, HSP90α, and RXRα (2022/04/06)
作者:Lingming Zhang, Jingdi Yan, Jianming Liu
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2022.154097
影响因子 :7.900
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Porous hydrogel arrays for hepatoma cell spheroid formation and drug resistance investigation(2021/07/17)
作者:Xin Lei, Changmin Shao, Xin Shou
期刊:Bio-Design and Manufacturing
DOI:10.1007/s42242-021-00141-8
影响因子 :7.900
引用产品:CL-0120
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Glycolysis, a new mechanism of oleuropein against liver tumor(2023/03/15)
作者:Zongchao Hong, Yi Lu, Bo Liu
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2023.154770
影响因子 :7.900
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β-catenin-IRP2-primed iron availability to mitochondrial metabolism is druggable for active β-catenin-mediated cancer(2023/01/26)
作者:Yuting Wu, Shuhui Yang, Luyang Han
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-023-03914-0
影响因子 :7.400
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The necroptosis related gene LGALS3 can be used as a biomarker for the adverse progression from chronic HBV infection to HCC(2023/04/26)
作者:Jianming Dong, Rongzheng Zhang, Yan Xia
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1142319
影响因子 :7.300
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Overcoming the resistance of hepatocellular carcinoma to PD-1/PD-L1 inhibitor and the resultant immunosuppression by CD38 siRNA-loaded extracellular vesicles(2022/12/26)
作者:Jun Deng, Hui Ke
期刊:OncoImmunology
DOI:10.1080/2162402X.2022.2152635
影响因子 :7.200
引用产品:CL-0120 CL-0278 CL-0323 CL-0497 CP-M131 PB180323 PM150110 PM150210
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VEZF1, destabilized by STUB1, affects cellular growth and metastasis of hepatocellular carcinoma by transcriptionally regulating PAQR4(2022/10/14)
作者:Xiaobao Shi, Pengfei Zhao, Gang Zhao
期刊:Cancer Gene Therapy
DOI:10.1038/s41417-022-00540-8
影响因子 :6.400
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CRHBP is degraded via autophagy and exerts anti-hepatocellular carcinoma effects by reducing cyclin B2 expression and dissociating cyclin B2-CDK1 complex(2022/01/27)
作者:Zhiwei Wang, Mingxing Li, Yuanfeng Liu
期刊:Cancer Gene Therapy
DOI:10.1038/s41417-021-00423-4
影响因子 :5.854
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Disulfiram enhances cisplatin cytotoxicity by forming a novel platinum chelate Pt(DDTC)3+(2023/03/11)
作者:Xuexia Yuan, Youfa Duan, Chunxiang Luo
期刊:BIOCHEMICAL PHARMACOLOGY
影响因子 :5.800
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CRISPR activation screening in a mouse model for drivers of hepatocellular carcinoma growth and metastasis(2023/02/02)
作者:Bei Zhang, Zhiyao Ren, Hongmei Zheng
期刊:iScience
DOI:10.1016/j.isci.2023.106099
影响因子 :5.800
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Tanshinone I induces cell apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and by suppressing p53/DRAM-mediated autophagy in human hepatocellular carcinoma(2020/2/4)
作者:Xu Liu, JiKui Liu
期刊:Artificial Cells Nanomedicine and Biotechnology
DOI:10.1080/21691401.2019.1709862
影响因子 :5.800
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Establishment of Prognostic Signatures of N6-Methyladenosine-Related lncRNAs and Their Potential Functions in Hepatocellular Carcinoma Patients(2022/06/06)
作者:Xianbin Wu, Zhejun Deng, Xiaomin Liao
期刊:Frontiers in Oncology
影响因子 :5.738
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Propofol exerts anticancer activity on hepatocellular carcinoma cells by raising lncRNA DGCR5(2019/09/19)
作者:Yan Sun, Hai Sun
期刊:Journal Of Cellular Physiology
影响因子 :5.600
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The E3 ubiquitin ligase SOCS-7 reverses immunosuppression via Shc1 signaling in hepatocellular carcinoma(2022/01/18)
作者:Peixin Huang, Zhiying Zhao, Yi Chen
期刊:Laboratory Investigation
DOI:10.1038/s41374-022-00727-5
影响因子 :5.502
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Lack of MOF Decreases Susceptibility to Hypoxia and Promotes Multidrug Resistance in Hepatocellular Carcinoma via HIF-1α(2021/09/01)
作者:Meng Wang, Haoyu Liu, Xu Zhang
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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The bioactive ingredients in Actinidia chinensis Planch. Inhibit liver cancer by inducing apoptosis(2021/08/21)
作者:Zongchao Hong, Yi Lu, Chongwang Ran
期刊:Journal Of Ethnopharmacology
影响因子 :5.400
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Circular RNA hsa_circ_0003141 promotes tumorigenesis of hepatocellular carcinoma via a miR-1827/UBAP2 axis.(2020/05/28)
作者:Yong Wang, Rongfen Gao, Jinpeng Li
期刊:Aging-US
影响因子 :5.200
引用产品:CL-0120
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Calycosin-7-glucoside promotes mitochondria-mediated apoptosis in hepatocellular carcinoma by targeting thioredoxin 1 to regulate oxidative stress(2023/02/21)
作者:Xiaodong Wei, Yanping Zeng, Fancheng Meng
期刊:CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 :5.100
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Asymmetric total synthesis and anti-hepatocellular carcinoma profile of enantiopure euphopilolide and jolkinolide E(2023/06/22)
作者:Xin Li, Jian Chen, Kaixuan Luo
期刊:BIOORGANIC CHEMISTRY
DOI:10.1016/j.bioorg.2023.106688
影响因子 :5.100
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Daphnetin inhibits the survival of hepatocellular carcinoma cells through regulating Wnt/β-catenin signaling pathway(2022/02/07)
作者:Chaohui Liu, Jiansheng Pan, Hongyu Liu
期刊:Drug Development Research
影响因子 :5.004
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Inhibition of FGFR2 Signaling by Cynaroside Attenuates Liver Fibrosis(2023/04/06)
作者:Qilin Meng, Lin Luo, Minghua Lei
期刊:Pharmaceuticals
影响因子 :4.600
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Circ_0007429/miR-637/TRIM71/Ago2 axis participates in the regulation of proliferation, migration, invasion, apoptosis, and aerobic glycolysis of HCC(2023/03/15)
作者:Lilan Fan, Panpan Xia, Jing Wang
期刊:MOLECULAR CARCINOGENESIS
DOI:10.1002/mc.23526
影响因子 :4.600
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Sorafenib/2800Z Co-Loaded into Cholesterol and PEG Grafted Polylysine NPs for Liver Cancer Treatment(2023/01/13)
作者:Chen Zhang, Wu Zhong, Ying Cao
期刊:Pharmaceuticals
影响因子 :4.600
引用产品:CL-0120
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KIN17 promotes cell migration and invasion through stimulating the TGF-β/Smad2 pathway in hepatocellular carcinoma(2022/12/05)
作者:Zichang Dai, Qiyuan Huang, Xueran Huang
期刊:MOLECULAR CARCINOGENESIS
DOI:10.1002/mc.23492
影响因子 :4.600
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Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1(2022/02/17)
作者:Hongyang Shi, Yonghong Zhang, Yu Wang
期刊:Toxicology And Applied Pharmacology
DOI:10.1016/j.taap.2022.115926
影响因子 :4.460
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Ultrasound-Targeted Microbubble Destruction-Mediated Downregulation of EZH2 Inhibits Stemness and Epithelial-Mesenchymal Transition of Liver Cancer Stem Cells(2021/01/11)
作者:Jie Wu, Lulu Sun, Tingting Liu
期刊:OncoTargets and Therapy
影响因子 :4.345
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ZSCAN16-AS1 expedites hepatocellular carcinoma progression via modulating the miR-181c-5p/SPAG9 axis to activate the JNK pathway(2021/06/07)
作者:Jianwen Liu, Ruiqing Liu, Yuyan Liu
期刊:Cell Cycle
DOI:10.1080/15384101.2021.1919828
影响因子 :4.300
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LINC00886 Facilitates Hepatocellular Carcinoma Tumorigenesis by Sequestering microRNA-409-3p and microRNA-214-5p(2023/06/07)
作者:Lu Li, Rong Ai, Xiwei Yuan
期刊:Journal of Hepatocellular Carcinoma
影响因子 :4.100
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Circular RNA circBNC2 facilitates glycolysis and stemness of hepatocellular carcinoma through the miR-217/high mobility group AT-hook 2 (HMGA2) axis.(2023/06/09)
作者:Yan Feng, Shufeng Xia, Junlan Hui
期刊:Heliyon
DOI:10.1016/j.heliyon.2023.e17120
影响因子 :4.000
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Long noncoding RNA HULC regulates the NF-κB pathway and represents a promising prognostic biomarker in liver cancer(2022/10/10)
作者:Shihai Liu, Lakshmi Huttad, Guifang He
期刊:Cancer Medicine
影响因子 :4.000
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Hsa_circ_0006916 Knockdown Represses the Development of Hepatocellular Carcinoma via Modulating miR-599/SRSF2 Axis(2020/11/4)
作者:Zhixiang Zhu, Songhe Shen, Sen Zhao
期刊:OncoTargets and Therapy
影响因子 :4.000
引用产品:CL-0120
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c-Jun-mediated JMJD6 restoration enhances resistance of liver cancer to radiotherapy through the IL-4-activated ERK pathway(2023/04/18)
作者:Yong Liu, Aixia Sui, Jirui Sun
期刊:CELL BIOLOGY INTERNATIONAL
影响因子 :3.900
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The expression characteristics and clinical significance of ACP6, a potential target of nitidine chloride, in hepatocellular carcinoma(2022/12/01)
作者:Li Gao, Dandan Xiong, Xia Yang
期刊:BMC CANCER
DOI:10.1186/s12885-022-10292-1
影响因子 :3.800
引用产品:CL-0120
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Hsa-miR-22-3p inhibits liver cancer cell EMT and cell migration/ invasion by indirectly regulating SPRY2(2023/02/07)
作者:Shuaishuai Cui, Yuanyuan Chen, Yunfei Guo
期刊:PLoS One
DOI:10.1371/journal.pone.0281536
影响因子 :3.700
引用产品:CL-0120
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AC093797.1 as a Potential Biomarker to Indicate the Prognosis of Hepatocellular Carcinoma and Inhibits Cell Proliferation, Invasion, and Migration by Reprogramming Cell Metabolism and Extracellular Matrix Dynamics(2021/12/03)
作者:Xiaoling Liu, Chenyu Wang, Qing Yang
期刊:Frontiers in Genetics
影响因子 :3.700
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BTF3 promotes proliferation and glycolysis in hepatocellular carcinoma by regulating GLUT1(2023/06/29)
作者:Peng Wang, Jianmin Sun, Chengming Sun
期刊:CANCER BIOLOGY & THERAPY
DOI:10.1080/15384047.2023.2225884
影响因子 :3.600
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Active compounds and potential targets of Shuganning injection in the treatment of hepatocellular carcinoma by network pharmacology and in vitro validation(2023/03/04)
作者:Xiao Han, Jiayan Huang, Jia Lu
期刊:NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
DOI:10.1007/s00210-023-02432-6
影响因子 :3.600
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PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway(2021/10/30)
作者:Gang Zhao, Xiaobao Shi, Zhanbo Sun
期刊:Acta Biochimica Et Biophysica Sinica
影响因子 :3.511
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PSPC1 regulates CHK1 phosphorylation through phase separation and participates in mouse oocyte maturation(2021/09/07)
作者:Li Jiong, Cui Peng, Sun Qi
期刊:Acta Biochimica Et Biophysica Sinica
影响因子 :3.511
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LncRNA FAM13A-AS1, transcriptionally regulated by PHOX2B, modulates hepatocellular carcinoma chemoresistance via stabilizing PPARγ(2023/06/16)
作者:Daowen Ye, Jun Ma, Tingdong Yu
期刊:GENE
DOI:10.1016/j.gene.2023.147570
影响因子 :3.500
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Complement factor H‑related 3 overexpression affects hepatocellular carcinoma proliferation and apoptosis(2019/7/23)
作者:Hong Liu, Ligang Zhang, Pengyan Wang
期刊:Molecular Medicine Reports
影响因子 :3.400
引用产品:CL-0120
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Circular RNA circ_0091579 Promotes Hepatocellular Carcinoma Proliferation, Migration, Invasion, and Glycolysis Through miR-490-5p/CASC3 Axis(2020/07/14)
作者:Wei Liu, Changbin Yin, Yue Liu
期刊:CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
影响因子 :3.400
引用产品:CL-0120
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Long noncoding RNA HAND2-AS1 reduced the viability of hepatocellular carcinoma via targeting microRNA-300/SOCS5 axis(202/3/12)
作者:Huaqiang Bi, Zhonghui Li, Hui Zhang
期刊:Hepatobiliary & Pancreatic Diseases International
DOI:10.1016/j.hbpd.2020.02.011.
影响因子 :3.300
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Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma(2022/01/25)
作者:Xu Qian, Zhongming Bao, Dan Yao
期刊:Kaohsiung Journal of Medical Sciences
影响因子 :3.300
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CircPVT1 Regulates Cell Proliferation, Apoptosis and Glycolysis in Hepatocellular Carcinoma via miR-377/TRIM23 Axis(2020/12/16)
作者:Nan Bu, Zheng Dong, Lingfeng Zhang
期刊:Cancer Management and Research
影响因子 :3.300
引用产品:CL-0120
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Lidocaine Inhibits Hepatocellular Carcinoma Development by Modulating circ_ITCH/miR-421/CPEB3 Axis(2021/1/12)
作者:Lili Zhao, Ning Ma, Gaihong Liu
期刊:Digestive Diseases And Sciences
DOI:10.1007/s10620-020-06787-1
影响因子 :3.100
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IL-35 promotes EMT through STAT3 activation and induces MET by promoting M2 macrophage polarization in HCC(2021/4/28)
作者:Yuan He, Jinhong Pei, Xueqing Li
期刊:Biochemical and Biophysical Research Communications
DOI:10.1016/j.bbrc.2021.04.050
影响因子 :3.100
引用产品:CL-0120
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miR-93-5p knockdown repressed hepatocellular carcinoma progression via increasing ERBB4 and TETs-dependent DNA demethylation(2021/08/26)
作者:Yuqiang Li, Bin Wu, Rongli Sun
期刊:Autoimmunity
DOI:10.1080/08916934.2021.1969552
影响因子 :2.957
引用产品:CL-0120
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Hyposterolactone A, a 3α-Hydroxy Steroidal Lactone from the Deep-Sea-Derived Fungus Hypocrea sp. ZEN14(2023/06/02)
作者:Lin Xu, Huabin Ma, Taizong Wu
期刊:CHEMISTRY & BIODIVERSITY
影响因子 :2.900
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Curcumin inhibits proliferation of hepatocellular carcinoma cells by blocking PTPN1 and PTPN11 expression(2023/06/01)
作者:Jingru Zhang, Yang Liu, Xiaojie Wang
期刊:Oncology Letters
影响因子 :2.900
引用产品:CL-0120
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(2E)-1-(2,4,6-Trimethoxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one, a Chalcone Derivative, Promotes Apoptosis by Suppressing RAS-ERK and AKT/FOXO3a Pathways in Hepatocellular Carcinoma Cells(2023/06/14)
作者:Meigui Zhang, Jing Li, Ruixia Ma
期刊:CHEMISTRY & BIODIVERSITY
影响因子 :2.900
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Folic acid modified TPGS as a novel nano-micelle for delivery of nitidine chloride to improve apoptosis induction in Huh7 human hepatocellular carcinoma(2021/1/6)
作者:Danni Li, Shaogang Liu, Jiahao Zhu
期刊:BMC Pharmacology & Toxicology
DOI:10.1186/s40360-020-00461-y
影响因子 :2.900
引用产品:CL-0120
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CKS1B promotes the progression of hepatocellular carcinoma by activating JAK/STAT3 signal pathway(2021/07/14)
作者:Xitao Liu, Defang Zhao
期刊:Animal Cells and Systems
DOI:10.1080/19768354.2021.1953142
影响因子 :2.900
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Metformin promotes ferroptosis and sensitivity to sorafenib in hepatocellular carcinoma cells via ATF4/STAT3(2023/06/16)
作者:Zongqiang Hu, Yingpeng Zhao, Laibang Li
期刊:MOLECULAR BIOLOGY REPORTS
DOI:10.1007/s11033-023-08492-4
影响因子 :2.800
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CXCL14 inhibits the growth and promotes apoptosis of hepatocellular carcinoma cells via suppressing Akt/mTOR pathway(2020/10/27)
作者:Jianqiang Bi, Quanle Liu, Yunchuan Sun
期刊:Journal Of Receptors And Signal Transduction
DOI:10.1080/10799893.2020.1837870
影响因子 :2.800
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PAIP1 regulates expression of immune and inflammatory response associated genes at transcript level in liver cancer cell(2023/04/21)
作者:Jianfeng Zheng, Weiwei Fan, Xiaoyu Zhang
期刊:PeerJ
影响因子 :2.700
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Centromere protein N may be a novel malignant prognostic biomarker for hepatocellular carcinoma(2021/5/3)
作者:Qingqing Wang, Xiaoyan Yu, Zhewen Zheng
期刊:PeerJ
影响因子 :2.700
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Exosome-derived GTF2H2 from Huh7 cells can inhibit endothelial cell viability, migration, tube formation, and permeability(2022/09/08)
作者:Zhenkun Li, Yanmeng Li, Qin Ouyang
期刊:TISSUE & CELL
DOI:10.1016/j.tice.2022.101922
影响因子 :2.600
引用产品:CL-0120
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Propofol enhances the lethality of cisplatin on liver cancer cells by up-regulating miR-195-5p(2021/11/19)
作者:Lan Gao, Xiufeng Zhang
期刊:Tissue & Cell
DOI:10.1016/j.tice.2021.101680
影响因子 :2.600
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CircRNA circBACH1 facilitates hepatitis B virus replication and hepatoma development by regulating the miR-200a-3p/MAP3K2 axis.(2022/02/03)
作者:Du N, Li K, Wang Y
期刊:Histology And Histopathology
影响因子 :2.000