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MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)
货号:CL-0149
规格:1×10⁶cells/T25培养瓶
价格: ¥1600
产品概述
名称 | MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确) |
别称 | MCF 7; MCF.7; MCF7; Michigan Cancer Foundation-7; ssMCF-7; ssMCF7; MCF7/WT; IBMF-7; MCF7-CTRL |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
生长培养基 | MEM(含NEAA)+10μg/mL Insulin+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:2-1:3 |
推荐换液频率 | 2~3次/周 |
背景描述 | MCF7 [MCF-7]细胞保留了多个分化了的乳腺上皮的特性,包括:能通过胞质雌激素受体加工雌二醇并能形成圆形复合物。MCF7 [MCF-7]细胞含有Tx-4癌基因;肿瘤坏死因子α可以抑制MCF7 [MCF-7]细胞的生长,抗雌激素处理MCF7 [MCF-7]细胞能调变IGFBP'S的分泌。 |
年龄(性别) | 女;69岁 |
组织来源 | 乳腺,乳房;源自转移部位:胸腔积液 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 乳腺癌细胞 |
生物安全等级 | 1 |
倍增时间 | ~30-72 hours |
受体表达情况 | estrogen receptor, expressed |
抗原表达情况 | Blood Type O; Rh+ |
基因表达情况 | insulin-like growth factor binding proteins (IGFBP) BP-2; BP-4; BP-5 |
保藏机构 | ATCC; CRL-12584ATCC; HTB-22 BCRC; 60436 BCRJ; 0162 DSMZ; ACC-115 ECACC; 86012803 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 10 D2S1338 21,23 D3S1358 16 D5S818 11,12 D7S820 8,9 D8S1179 10,14 D13S317 11 D16S539 11,12 D18S51 14 D19S433 13,14 D21S11 30 FGA 23,25 PentaD 12 PentaE 7,12 TH01 6 TPOX 9,12 vWA 14,15 D6S1043 12,18 D12S391 18,20 D2S441 10,14 -
STR鉴定图
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参考文献
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影响因子 :4.600
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De Novo Design of Imidazopyridine-Tethered Pyrazolines That Target Phosphorylation of STAT3 in Human Breast Cancer Cells(2023/01/24)
作者:Akshay Ravish, Rashmi Shivakumar, Zhang Xi
期刊:Bioengineering-Basel
DOI:10.3390/bioengineering10020159
影响因子 :4.600
引用产品:CL-0149
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The Anti-Breast Cancer Activity of Dihydroartemisinin-5-methylisatin Hybrids Tethered via Different Carbon Spacers(2022/11/18)
作者:Yanfen Yao, Hong Wang, Jing Xu, Feng Gao, Wei Cao
期刊:MOLECULES
影响因子 :4.600
引用产品:CL-0149
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A ratiometric near-infrared fluorescence strategy based on spiropyran in situ switching for tracking dynamic changes of live-cell lysosomal pH(2019/03/27)
作者:Jin Li, Xiaokang Li, Jianbo Jia
期刊:Dyes And Pigments
DOI:10.1016/j.dyepig.2019.03.060
影响因子 :4.500
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Highly efficient and simultaneous production of thirteen taxanes from Taxus × media and mining of their new bioactivity(2023/06/16)
作者:Hua Zhang, Liming Huang, Ya Wu
期刊:PROCESS BIOCHEMISTRY
DOI:10.1016/j.procbio.2023.06.012
影响因子 :4.400
引用产品:CL-0149
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Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6(2020/6/11)
作者:Meng Jin, Daili Gao, Rongchun Wang
期刊:Oncology Reports
影响因子 :4.200
引用产品:CL-0149
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A colorimetric and near -infrared ratiometric fluorescent probe for the determination of endogenous tyrosinase activity based on cyanine aggregation(2019/09/21)
作者:Peng Zhang, Shasha Li, Caixia Fu
期刊:Analyst
影响因子 :4.200
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DNA nanolantern-based split aptamer probes for in situ ATP imaging in living cells and lighting up mitochondria(2021/03/02)
作者:Yaxin Wang, Dongxia Wang, Jiayi Ma
期刊:Analyst
影响因子 :4.200
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Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6(2020/06/11)
作者:Meng Jin, Daili Gao, Rongchun Wang
期刊:Oncology Reports
影响因子 :4.200
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Selinexor improves the anti-cancer effect of tucidinostat on TP53 wild-type breast cancer(2022/01/13)
作者:Yingfang Shi, Shengxi Xu, Sen Li
期刊:MOLECULAR AND CELLULAR ENDOCRINOLOGY
影响因子 :4.100
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Development of the expression and prognostic significance of m5C-related LncRNAs in breast cancer(2022/12/04)
作者:Gaoran Xu, Chengxin Li, Ziyang Di
期刊:Cancer Medicine
影响因子 :4.000
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Hyaluronic acid functionalized biodegradable mesoporous silica nanocomposites for efficient photothermal and chemotherapy in breast cancer(2021/01/29)
作者:Wenhua Zhan, Hanrui Li, Yingying Guo
期刊:Nanotechnology
影响因子 :3.953
引用产品:CL-0149
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Nano-ZrO2-Catalyzed Biginelli Reaction and the Synthesis of Bioactive Dihydropyrimidinones That Targets PPAR-γ in Human Breast Cancer Cells(2023/01/18)
作者:Suresha N. Deveshegowda, Jirui Yang, Zhang Xi
期刊:Catalysts
影响因子 :3.900
引用产品:CL-0149
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Binding of combined irinotecan and epicatechin to a pH-responsive DNA tetrahedron for controlled release and enhanced cytotoxicity(2023/03/10)
作者:Lu Wang, Yushu Wu, Tianxin Weng
期刊:JOURNAL OF MOLECULAR STRUCTURE
DOI:10.1016/j.molstruc.2023.135323
影响因子 :3.800
引用产品:CL-0149
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Ferroptosis regulators, especially SQLE, play an important role in prognosis, progression and immune environment of breast cancer(2021/10/29)
作者:Wenqing Tang, Fangshi Xu, Meng Zhao
期刊:Bmc Cancer
DOI:10.1186/s12885-021-08892-4
影响因子 :3.800
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The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway(2022/09/09)
作者:Jiao Yu, Kai Wang, Sanhu Yang
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2022.116232
影响因子 :3.800
引用产品:CL-0041 CL-0114 CL-0149 CL-0228 CL-0324 CL-0525 PM150110 PM150312 PM150411
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Isopimaric acid, an ion channel regulator, regulates calcium and oxidative phosphorylation pathways to inhibit breast cancer proliferation and metastasis(2023/02/06)
作者:Jiacheng Li, Xiaozhen Liu, Lin Chen
期刊:TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI:10.1016/j.taap.2023.116415
影响因子 :3.800
引用产品:CL-0007 CL-0093 CL-0149 CL-0150B CL-0152B CL-0525 P-CA-201
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PAIP2 is a potential diagnostic and prognostic biomarker of breast cancer and is associated with immune infiltration.(2022/11/10)
作者:Chenyu Wang, Xianglai Jiang, Jiaojiao Qi, Jiachao Xu, Guangfei Yang, Chengrong Mi, DataSheet2.PDF, Image1.JPEG, DataSheet1.PDF
期刊:Frontiers in Genetics
DOI:10.3389/fgene.2022.1009056
影响因子 :3.700
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Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer(2020/12/13)
作者:Lin Niu, Songhe Yang, Xueying Zhao
期刊:Molecular Medicine Reports
影响因子 :3.400
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The anti-breast cancer potential of dihydroartemisinin-isatin hybrids with hydrogen bond donors at C-3 position of isatin moiety(2023/01/03)
作者:Feng Ding, Xiao Chen, Wei Cao
期刊:FITOTERAPIA
DOI:10.1016/j.fitote.2023.105426
影响因子 :3.400
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Design, synthesis, and in vitro cytotoxicity evaluation of novel dihydroartemisinin-isatin hybrids tethered via different length of esters as potential anti-breast cancer agents(2023/01/21)
作者:Zhi Xu, Bowen Pan, Linzhi Chen
期刊:FITOTERAPIA
DOI:10.1016/j.fitote.2023.105436
影响因子 :3.400
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Preparation and bioevaluation of [99mTc]Tc-labeled A7R and DA7R for SPECT imaging of triple-negative breast cancer(2022/10/25)
作者:Hongxing Su, Lingzhou Zhao, Buhui Yu
期刊:NEW JOURNAL OF CHEMISTRY
影响因子 :3.300
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Nickel-Doped Microfluidic Chip for Rapid and Efficient Immunomagnetic Separation and Detection of Breast Cancer Cell-Derived Exosomes(2022/12/21)
作者:Huiying Fang, Mei Liu, Wei Jiang
期刊:APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
DOI:10.1007/s12010-022-04272-1
影响因子 :3.000
引用产品:CL-0149
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Saikosaponin A alleviates glycolysis of breast cancer cells through repression of Akt/STAT3 pathway(2023/04/23)
作者:Yan Zhang, Kun Dai, Dedong Xu
期刊:Chemical Biology & Drug Design
影响因子 :3.000
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Design, synthesis, and biological evaluation of novel amyl ester tethered dihydroartemisinin-isatin hybrids as potent anti-breast cancer agents(2023/02/20)
作者:Zhi Xu, Xiaoyan Zhang, Jie Liu
期刊:CHEMISTRY & BIODIVERSITY
影响因子 :2.900
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Deciphering the map of METTL14-mediated lncRNA m6A modification at the transcriptome-wide level in breast cancer(2022/11/06)
作者:Dandan Yi, Fazhan Xu, Ru Wang, Chaoyu Jiang, Jiabo Qin, YiHsuan Lee, Xianbiao Shi, Jianfeng Sang
期刊:JOURNAL OF CLINICAL LABORATORY ANALYSIS
影响因子 :2.700
-
PRAF2 is an oncogene acting to promote the proliferation and invasion of breast cancer cells(2022/11/01)
作者:Yabing Wang, Zhiyong Zhao, Wei Jiao, Zhaocai Yin, Wanjun Zhao, Hongguang Bo, Zilin Bi, Bingbin Dong, Bin Chen, Zheng Wang
期刊:Experimental and Therapeutic Medicine
影响因子 :2.700
引用产品:CL-0149
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Overexpression of HOXD8 inhibits the proliferation, migration and invasion of breast cancer cells by downregulating ILP2 expression(2021/7/15)
作者:Xiaoyun Wen,Yu Chen, Xiansong Fang
期刊:Experimental and Therapeutic Medicine
影响因子 :2.700
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Design, synthesis and anti-breast cancer properties of butyric ester tethered dihydroartemisinin-isatin hybrids(2023/02/14)
作者:Shijia Zhao, Xiaoyan Zhang, Min Tang
期刊:MEDICINAL CHEMISTRY RESEARCH
DOI:10.1007/s00044-023-03030-0
影响因子 :2.600
引用产品:CL-0149
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Construction of the targeted and pH-sensitive paclitaxel drug delivery system RGD/PTX@ZIF-90 and anti-tumor activity research(2021/04/16)
作者:Fei Ge, Rui Qiao, Ping Song
期刊:Materials Research Express
影响因子 :2.300
引用产品:CL-0149
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Expression and Clinical Significance of TIGIT in Primary Breast Cancer(2023/06/12)
作者:Limin Tang, Min Sha, Ting Guo
期刊:International Journal of General Medicine
影响因子 :2.300
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Effect of pluronic block composition on the structure, stability, and cytotoxicity of liposomes(2020/06/12)
作者:Ziling Li, Xiangyuan Xiong, Shengfeng Peng
期刊:Journal of Dispersion Science and Technology
DOI:10.1080/01932691.2020.1776130
影响因子 :2.200
引用产品:CL-0149
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7-Methoxy-13-dehydroxypaxilline: New indole diterpenoid from an endophytic fungus Penicillium sp. Nb 19(2022/08/05)
作者:Jing Yu, Jiapeng Wang, Shifang Liu
期刊:NATURAL PRODUCT RESEARCH
DOI:10.1080/14786419.2022.2107639
影响因子 :2.200
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Inhibition of glycolysis represses the growth and alleviates the endoplasmic reticulum stress of breast cancer cells by regulating TMTC3(2023/04/10)
作者:Xue Hu, Baoliang Guo, Tong Sun
期刊:Open Medicine
影响因子 :2.100
引用产品:164210 164215 CL-0149 CL-0211 CL-0525 PB180120 PB180424 PM150140 PM150312 PM150710 PM151010
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CircRNA DNA methyltransferase 1 silence inhibits breast cancer development by regulating micoRNA-485-3p/zinc finger E-box binding homeobox 1 axis(2021/01/05)
作者:Chen Xie, Junyu Li, Chen Xu
期刊:Journal Of Obstetrics And Gynaecology Research
影响因子 :1.600
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AXL upregulates c‑Myc expression through AKT and ERK signaling pathways in breast cancers(2023/02/08)
作者:Xiaobai Sun, Hong Chen, Shuling You
期刊:Molecular and Clinical Oncology
影响因子 :1.200
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In vitro study of piwi interaction RNA-31106 promoting breast carcinogenesis by regulating METTL3-mediated m6A RNA methylation(2023/06/30)
作者:Shengchao Huang, Baoying Chen, Pu Qiu
期刊:Translational Cancer Research
影响因子 :0.900