产品中心Cell Resources
联系我们CONTACT US
400-999-210024小时服务热线
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0149-1.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0149-2.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0149-3.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0149-4.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0149-5.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/xbx/CL-0149-6.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](/Public/upfile/pic/product/cell-line-new.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0149-1.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0149-2.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0149-3.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0149-4.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0149-5.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/xbx/CL-0149-6.jpg)
![MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确)](http://www.procell.com.cn/Public/upfile/pic/product/cell-line-new.jpg)
产品概述
| 名称 | MCF7 [MCF-7] (人乳腺癌细胞) (STR鉴定正确) |
| 别称 | MCF 7; MCF.7; MCF7; Michigan Cancer Foundation-7; ssMCF-7; ssMCF7; MCF7/WT; IBMF-7; MCF7-CTRL |
| 背景描述 | MCF7 [MCF-7]细胞保留了多个分化了的乳腺上皮的特性，包括：能通过胞质雌激素受体加工雌二醇并能形成圆形复合物。MCF7 [MCF-7]细胞含有Tx-4癌基因；肿瘤坏死因子α可以抑制MCF7 [MCF-7]细胞的生长，抗雌激素处理MCF7 [MCF-7]细胞能调变IGFBP'S的分泌。 |
| 种属 | 人 |
| 年龄（性别） | 女；69岁 |
| 组织来源 | 乳腺，乳房；源自转移部位：胸腔积液 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 乳腺癌细胞 |
| 生物安全等级 | 1 |
| 生长培养基 | MEM（含NEAA）＋0.01mg/ml Insulin＋10% FBS＋1% P/S |
| 推荐传代比例 | 1:2-1:3 |
| 推荐换液频率 | 2~3次/周 |
| 倍增时间 | ~30-72 hours |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 受体表达情况 | estrogen receptor, expressed |
| 抗原表达情况 | Blood Type O; Rh+ |
| 基因表达情况 | insulin-like growth factor binding proteins (IGFBP) BP-2; BP-4; BP-5 |
| 保藏机构 | ATCC; CRL-12584ATCC; HTB-22 BCRC; 60436 BCRJ; 0162 DSMZ; ACC-115 ECACC; 86012803 |
STR鉴定
-
STR位点信息
Amelogenin X CSF1PO 10 D2S1338 21,23 D3S1358 16 D5S818 11,12 D7S820 8,9 D8S1179 10,14 D13S317 11 D16S539 11,12 D18S51 14 D19S433 13,14 D21S11 30 FGA 23,25 PentaD 12 PentaE 7,12 TH01 6 TPOX 9,12 vWA 14,15 D6S1043 12,18 D12S391 18,20 D2S441 10,14 -
STR鉴定图
-
参考文献
-
SO2 prodrug doped nanorattles with extra-high drug payload for “collusion inside and outside” photothermal/pH triggered - gas therapy(2020/7/13)
作者：Qianglan Lu, TongLu, Min Xu
期刊：Biomaterials
DOI：10.1016/j.biomaterials.2020.120236
影响因子 ：15.304
引用产品：CL-0149
-
Zebrafish xenograft model for studying mechanism and treatment of non-small cell lung cancer brain metastasis(2021/11/20)
作者：Ruoyue Fan, Jiaqi Wu, Yuyang Liu
期刊：Journal Of Experimental & Clinical Cancer Research
DOI：10.1186/s13046-021-02173-5
影响因子 ：12.6580
-
Photoelectrochemical cell enhanced by ternary heterostructured photoanode: Toward high-performance self-powered cathodic cytosensing(2019/07/15)
作者：Gaochao Fan, Yanwei Lu, Huan Zhao
期刊：Biosens Bioelectron
DOI：10.1016/j.bios.2019.04.063
影响因子 ：12.545
-
Target-induced formation of multiple DNAzymes in solid-state nanochannels: Toward innovative photoelectrochemical probing of telomerase activity(2019/10/01)
作者：Gaochao Fan, Yanwei Lu, Linzheng Ma
期刊：Biosens Bioelectron .
DOI：10.1016/j.bios.2019.111564
影响因子 ：12.545
-
Electrochemical biosensor for ultrasensitive exosomal miRNA analysis by cascade primer exchange reaction and MOF@Pt@MOF nanozyme(2020/08/25)
作者：Xinyu Li, Xinmin Li, Dandan Li
期刊：Biosensors & Bioelectronics
DOI：10.1016/j.bios.2020.112554
影响因子 ：12.545
引用产品：CL-0149
-
Target-induced formation of multiple DNAzymes in solid-state nanochannels: Toward innovative photoelectrochemical probing of telomerase activity(2019/08/02)
作者：Gaochao Fan, Yanwei Lu, Linzheng Ma
期刊：Biosensors & Bioelectronics
DOI：10.1016/j.bios.2019.111564
影响因子 ：12.545
-
A facile homogeneous electrochemical biosensing strategy based on displacement reaction for intracellular and extracellular hydrogen peroxide detection(2019/06/19)
作者：Fengjuan Liu, Limin Yang, Xuehan Yin
期刊：Biosensors & Bioelectronics
DOI：10.1016/j.bios.2019.111446
影响因子 ：12.545
引用产品：CL-0149
-
Photoelectrochemical cell enhanced by ternary heterostructured photoanode: Toward high-performance self-powered cathodic cytosensing(2019/05/03)
作者：Gaochao Fan, Yanwei Lu, Huan Zhao
期刊：Biosensors & Bioelectronics
DOI：10.1016/j.bios.2019.04.063
影响因子 ：12.545
-
A Highly Sensitive Strategy for Fluorescence Imaging of MicroRNA in Living Cells and in Vivo Based on Graphene Oxide-Enhanced Signal Molecules Quenching of Molecular Beacon(2018/02/15)
作者：Limin Yang, Bo Liu, Meimei Wang
期刊：ACS Applied Materials & Interfaces
影响因子 ：10.3830
-
Hyaluronic Acid-Functionalized Gold Nanorods with pH/NIR Dual-Responsive Drug Release for Synergetic Targeted Photothermal Chemotherapy of Breast Cancer(2017/10/12)
作者：Weijun Xu, Junmin Qian, Guanghui Hou
期刊：ACS Applied Materials & Interfaces
影响因子 ：10.3830
引用产品：CL-0149
-
Cadmium promotes breast cancer cell proliferation, migration and invasion by inhibiting ACSS2/ATG5-mediated autophagy(2021/01/15)
作者：Yidan Liang, Huifeng Pi, Lingzhi Liao
期刊：Environmental Pollution
DOI：10.1016/j.envpol.2021.116504
影响因子 ：9.988
-
Phenotype-related drug sensitivity analysis of single CTCs for medicine evaluation(2020/08/10)
作者：Haimeng Pei, Mei Yu, Defang Dong
期刊：Chemical Science
影响因子 ：9.969
-
Up-regulated circBACH2 contributes to cell proliferation, invasion, and migration of triple-negative breast cancer(2021/4/19)
作者：Xinxing Wang, Bingjian Xue, Yujie Zhang
期刊：Cell Death & Disease
DOI：10.1038/s41419-021-03684-x
影响因子 ：9.685
引用产品：CL-0040 CL-0041 CL-0149 CL-0150A CL-0150B CL-0152A CL-0152B CL-0290A CL-0290B CL-0525
-
Lignin-Based Hydrogen-Bonded Covalent Organic Polymers as Functional “Switches” of Modified Atmosphere Packaging Membranes for Preservation of Perishable Foods(2022/08/08)
作者：Zhanchao Li, Wei Li, Dongxia Wang
期刊：ACS Sustainable Chemistry & Engineering
DOI：10.1021/acssuschemeng.2c01735
影响因子 ：9.2240
引用产品：CL-0149
-
Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization(2017/05/08)
作者：H Guo, Q Zhu, X Yu
期刊：Oncogene
影响因子 ：8.756
-
A graphene-based fluorescent nanoprobe for simultaneous monitoring of miRNA and mRNA in living cells(2018/06/29)
作者：Wei Pan, Bo Liu, Xiaonan Gao
期刊：Nanoscale
影响因子 ：8.307
-
Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex(2022/09/19)
作者：Maolin Li, Jingmei Yuan, Hao Yuan
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.2c00467
影响因子 ：8.0390
-
Characterization of a polysaccharide from Sanghuangporus vaninii and its antitumor regulation via activation of the p53 signaling pathway in breast cancer MCF-7 cells(2020/11/15)
作者：Xilin Wan, Xin Jin, Mengle Xie
期刊：International Journal of Biological Macromolecules
DOI：10.1016/j.ijbiomac.2020.06.279
影响因子 ：8.025
-
Accurate and Nonpurified Identification of Extracellular Vesicles Using Dual-Binding Recognition Mode(2021/8/27)
作者：Wenyu Sun, Yu Wang, Zhixue Zhu
期刊：Analytical Chemistry
DOI：10.1021/acs.analchem.1c02259
影响因子 ：8.0080
-
Metal–Organic Framework-Functionalized Paper-Based Electrochemical Biosensor for Ultrasensitive Exosome Assay(2021/8/19)
作者：Xiaojuan Liu, Xin Gao, Limin Yang
期刊：Analytical Chemistry
DOI：10.1021/acs.analchem.1c02286
影响因子 ：8.0080
引用产品：CL-0149
-
Pumping-controlled multicolor modulation of upconversion emission for dual-mode dynamic anti-counterfeiting(2020/06/01)
作者：Xiaoru Dai, Ke Wang, Lei Lei
期刊：Nanophotonics
影响因子 ：7.923
-
Low Dose of Paclitaxel Combined with XAV939 Attenuates Metastasis, Angiogenesis and Growth in Breast Cancer by Suppressing Wnt Signaling(2019/08/14)
作者：Dattatrya Shetti, Bao Zhang
期刊：Cells
影响因子 ：7.666
-
miR-29b-3p promotes progression of MDA-MB-231 triple-negative breast cancer cells through downregulating TRAF3(2019/7/26)
作者：Bao Zhang, Shetti, Dattatrya
期刊：Biological Research
影响因子 ：7.6340
-
Neural network-enhanced real-time impedance flow cytometry for single-cell intrinsic characterization(2022/1/18)
作者：Yongxiang Feng, Zhen Cheng, Huichao Chai
期刊：Lab on a Chip
影响因子 ：7.5170
-
A microfluidic device enabling deterministic single cell trapping and release(2021/05/20)
作者：Chai Huichao, Feng Yongxiang, Liang Fei
期刊：Lab On A Chip
影响因子 ：7.517
引用产品：CL-0149
-
Small nucleolar RNA SNORA71A promotes epithelial-mesenchymal transition by maintaining ROCK2 mRNA stability in breast cancer(2022/03/30)
作者：Ting Hu, Chong Lu, Yun Xia
期刊：Molecular Oncology
影响因子 ：7.4490
-
N6-methyladenosine-mediated downregulation of miR-374c-5p promotes cadmium-induced cell proliferation and metastasis by targeting GRM3 in breast cancer cells( 2021/12/15)
作者：Yang Yue, Ping Deng, Heng Xiao
期刊： ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2021.113085
影响因子 ：7.1290
-
Rapamycin antagonizes cadmium-induced breast cancer cell proliferation and metastasis through directly modulating ACSS2(2021/08/16)
作者：Yidan Liang, Lai Yi, Ping Deng
期刊：Ecotoxicology And Environmental Safety
DOI：10.1016/j.ecoenv.2021.112626
影响因子 ：7.129
-
Novel 4-anilinoquinazoline derivatives featuring an 1-adamantylmoiety as potent EGFR inhibitors with enhanced activity againstNSCLC cell lines(2016/01/26)
作者：Haiqing Yu, Yanxia Li, Yang Ge
期刊：European Journal of Medicinal Chemistry
DOI：DOI: 10.1016/j.ejmech.2016.01.045
影响因子 ：7.088
-
Intelligent triggering of nanomicelles based on a ROS-activated anticancer prodrug and photodynamic therapy (PDT)-synergistic therapy for lung cancers(2022/08/03)
作者：Lixue Chen, Ruping Xu, Yanfang Ding
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2022.114622
影响因子 ：7.0880
-
A Combined Self-Assembled Drug Delivery for Effective Anti-Breast Cancer Therapy(2021/03/23)
作者：Hairong Wang, Yawen Zhang, Xiangle Zeng
期刊：International Journal of Nanomedicine
影响因子 ：7.0330
-
Single-Cell Phenotypic Profiling of CTCs in Whole Blood Using an Integrated Microfluidic Device(2019/08/02)
作者：Haimeng Pei, Lu Li
期刊：Anal. Chem
DOI：10.1021/acs.analchem.9b01647
影响因子 ：6.9860
-
Highly Soluble and Stable, High Release Rate Nanocellulose Codrug Delivery System of Curcumin and AuNPs for Dual Chemo-Photothermal Therapy(2022/01/14)
作者：Yan Tian, Dongmei Jia, Mahmut Dirican
期刊：Biomacromolecules
DOI：10.1021/acs.biomac.1c01367
影响因子 ：6.9780
-
Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin(2021/6/2)
作者：Yan Wang, Zhiqiang Cheng, Jing Xu
期刊：Bioengineered
DOI：10.1080/21655979.2021.1924544
影响因子 ：6.8320
-
Solasodine suppress MCF7 breast cancer stem-like cells via targeting Hedgehog/Gli1(2022/09/06)
作者：Jing Chen, Da Ma, Cuicui Zeng
期刊：PHYTOMEDICINE
DOI：10.1016/j.phymed.2022.154448
影响因子 ：6.6560
引用产品：CL-0149
-
Idarubicin/mithramycin-acridine orange combination drugs co-loaded by DNA nanostructures: Different effects of intercalation and groove binding on drug release and cytotoxicity(2022/03/17)
作者：Danfeng Wang, Min Liu, Yushu Wu
期刊：Journal Of Molecular Liquids
DOI：10.1016/j.molliq.2022.118947
影响因子 ：6.6330
引用产品：CL-0149
-
UBE2C affects breast cancer proliferation through the AKT/mTOR signaling pathway(2021/10/20)
作者：Zinan Lu, Jia Song, Tonghui Sun
期刊：Chinese Medical Journal
DOI：10.1097/CM9.0000000000001708
影响因子 ：6.1330
-
A gold–selenium-bonded nanoprobe for real-time in situ imaging of the upstream and downstream relationship between uPA and MMP-9 in cancer cells(2019/03/16)
作者：Mingming Luan
期刊：Chem Commun
影响因子 ：6.065
-
A System Pharmacology Model for Decoding the Synergistic Mechanisms of Compound Kushen Injection in Treating Breast Cancer(2021/11/16)
作者：Yi Li, Kexin Wang, Yupeng Chen
期刊：Frontiers in Pharmacology
影响因子 ：5.9880
引用产品：CL-0149
-
A Modular Coassembly Approach to All-In-One Multifunctional Nanoplatform for Synergistic Codelivery of Doxorubicin and Curcumin(2018/03/15)
作者：Muyang Yang, Lixia Yu, Ruiwei Guo
期刊：Nanomaterials
影响因子 ：5.7190
-
Systematic screening reveals synergistic interactions that overcome MAPK inhibitor resistance in cancer cells(2021/6/9)
作者：Yu Yu, Minzhen Tao, Libin Xu
期刊：Cancer Biology & Medicine
DOI：10.20892/j.issn.2095-3941.2020.0560
影响因子 ：5.3470
-
A colorimetric and near -infrared ratiometric fluorescent probe for the determination of endogenous tyrosinase activity based on cyanine aggregation(2019/09/21)
作者：Peng Zhang, Shasha Li, Caixia Fu
期刊：Analyst
影响因子 ：5.227
-
DNA nanolantern-based split aptamer probes for in situ ATP imaging in living cells and lighting up mitochondria(2021/03/02)
作者：Yaxin Wang, Dongxia Wang, Jiayi Ma
期刊：Analyst
影响因子 ：5.227
-
Quercus acutissima Carruth. root extract triggers apoptosis, autophagy and inhibits cell viability in breast cancer cells(2022/01/29 )
作者：Wenjing Ding, Chen Chen, Jun Li
期刊： journal of ethnopharmacology
影响因子 ：5.1950
-
Jolkinolide B inhibits proliferation or migration and promotes apoptosis of MCF-7 or BT-474 breast cancer cells by downregulating the PI3K-Akt pathway(2021/08/28)
作者：Yang Wang, Shiyang Shen, Lei Liu
期刊：Journal Of Ethnopharmacology
影响因子 ：5.195
-
A ratiometric near-infrared fluorescence strategy based on spiropyran in situ switching for tracking dynamic changes of live-cell lysosomal pH(2019/03/27)
作者：Jin Li, Xiaokang Li, Jianbo Jia
期刊：Dyes And Pigments
DOI：10.1016/j.dyepig.2019.03.060
影响因子 ：5.122
-
Rutaecarpine Increases Anticancer Drug Sensitivity in Drug-Resistant Cells through MARCH8-Dependent ABCB1 Degradation(2021/09/02)
作者：Tingting Zou, Cheng Zeng, Junyan Qu
期刊：Biomedicines
DOI：10.3390/biomedicines9091143
影响因子 ：4.757
-
Ferroptosis regulators, especially SQLE, play an important role in prognosis, progression and immune environment of breast cancer(2021/10/29)
作者：Wenqing Tang, Fangshi Xu, Meng Zhao
期刊：Bmc Cancer
DOI：10.1186/s12885-021-08892-4
影响因子 ：4.638
-
The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway(2022/09/09)
作者：Jiao Yu, Kai Wang, Sanhu Yang
期刊：TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI：10.1016/j.taap.2022.116232
影响因子 ：4.4600
引用产品：CL-0041 CL-0114 CL-0149 CL-0228 CL-0324 CL-0525 PM150110 PM150312 PM150411
-
Selinexor improves the anti-cancer effect of tucidinostat on TP53 wild-type breast cancer(2022/01/13)
作者：Yingfang Shi, Shengxi Xu, Sen Li
期刊：MOLECULAR AND CELLULAR ENDOCRINOLOGY
影响因子 ：4.3690
-
Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6(2020/6/11)
作者：Meng Jin, Daili Gao, Rongchun Wang
期刊：Oncol Rep
影响因子 ：4.1360
引用产品：CL-0149
-
Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6(2020/06/11)
作者：Meng Jin, Daili Gao, Rongchun Wang
期刊：Oncology Reports
影响因子 ：4.136
-
Preparation and bioevaluation of [99mTc]Tc-labeled A7R and DA7R for SPECT imaging of triple-negative breast cancer(2022/10/25)
作者：Hongxing Su, Lingzhou Zhao, Buhui Yu
期刊：NEW JOURNAL OF CHEMISTRY
影响因子 ：3.9250
-
Sericin inhibits MDA‑MB‑468 cell proliferation via the PI3K/Akt pathway in triple‑negative breast cancer(2020/12/13)
作者：Lin Niu, Songhe Yang, Xueying Zhao
期刊：Molecular Medicine Reports
影响因子 ：3.4230
-
Overexpression of HOXD8 inhibits the proliferation, migration and invasion of breast cancer cells by downregulating ILP2 expression(2021/7/15)
作者：Xiaoyun Wen,Yu Chen, Xiansong Fang
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.7510
-
7-Methoxy-13-dehydroxypaxilline: New indole diterpenoid from an endophytic fungus Penicillium sp. Nb 19(2022/08/05)
作者：Jing Yu, Jiapeng Wang, Shifang Liu
期刊：NATURAL PRODUCT RESEARCH
DOI：10.1080/14786419.2022.2107639
影响因子 ：2.4880
-
Effect of pluronic block composition on the structure, stability, and cytotoxicity of liposomes(2020/06/12)
作者：Ziling Li, Xiangyuan Xiong, Shengfeng Peng
期刊：Journal of Dispersion Science and Technology
DOI：10.1080/01932691.2020.1776130
影响因子 ：2.0420
引用产品：CL-0149
-
Construction of the targeted and pH-sensitive paclitaxel drug delivery system RGD/PTX@ZIF-90 and anti-tumor activity research(2021/04/16)
作者：Fei Ge, Rui Qiao, Ping Song
期刊：Materials Research Express
影响因子 ：2.0250
引用产品：CL-0149
-
CircRNA DNA methyltransferase 1 silence inhibits breast cancer development by regulating micoRNA-485-3p/zinc finger E-box binding homeobox 1 axis(2021/01/05)
作者：Chen Xie, Junyu Li, Chen Xu
期刊：Journal Of Obstetrics And Gynaecology Research
影响因子 ：1.6970
