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产品概述
名称 | BV2 (小鼠小胶质细胞) (种属鉴定正确) |
别称 | BV-2 |
种属 | 小鼠 |
年龄(性别) | 不详 |
组织来源 | 脑;胶质瘤 |
生长特性 | 半贴半悬 |
细胞形态 | 上皮细胞样 |
背景描述 | BV-2细胞是由E·Blasi建立于1990年;BV-2细胞由小鼠小神经胶质细胞经逆转录病毒介导转染v-raf/v-myc获永生化。BV-2细胞保留有小神经胶质细胞多种形态、表征和功能特征;免疫组化结果显示,BV-2细胞为MAC1、MAC2阳性;而MAC3、胶质细胞原纤维酸性蛋白、半乳糖脑苷脂为阴性。 |
生长培养基 | MEM+10% FBS+1% P/S |
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2~3次/周 |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
STR鉴定
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STR位点信息
18-3 16,17 9-2 17.3 6-7 15 5-5 17 X-1 27 15-3 22.3,23.3,24.3 12-1 17 6-4 18 4-2 20.3 jaridl X -
STR鉴定图
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参考文献
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NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma(2020/4/15)
作者:Hui Chen, Yang Deng, Xiaoliang Gan
期刊:Molecular Neurodegeneration
DOI:10.1186/s13024-020-00372-w
影响因子 :14.195
引用产品:CL-0493
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Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice(2022/2/10)
作者:Libin Ni, Jian Xiao, Di Zhang
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-04592-4
影响因子 :8.4690
引用产品:CL-0493
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The Regulatory NOD-Like Receptor NLRC5 Promotes Ganglion Cell Death in Ischemic Retinopathy by Inducing Microglial Pyroptosis(2021/5/20)
作者:Yang Deng, Yunzhao Fu, Longxiang Sheng
期刊:Frontiers in Cell and Developmental Biology
影响因子 :6.684
引用产品:CL-0493
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Study on the antidepressant effect of panaxynol through the IκB-α/NF-κB signaling pathway to inhibit the excessive activation of BV-2 microglia(2021/03/13)
作者:Yan Zhao, Xialin Sun, Tingwen Zhang
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2021.111387
影响因子 :6.529
引用产品:CL-0493
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Design and synthesis of 3-(4-pyridyl)-5-(4-sulfamido-phenyl)-1,2,4-oxadiazole derivatives as novel GSK-3β inhibitors and evaluation of their potential as multifunctional anti-Alzheimer agents(2020/09/28)
作者:Min Wang, Tongtong Liu, Shiming Chen
期刊:European Journal Of Medicinal Chemistry
DOI:10.1016/j.ejmech.2020.112874
影响因子 :6.514
引用产品:CL-0493
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DOK3 is involved in microglial cell activation in neuropathic pain by interacting with GPR84(2020/12/3)
作者:Wenshuang Gao, Yujuan Qu, Juan Huai
期刊:Aging-US
影响因子 :5.682
引用产品:CL-0493
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The protective effect of 5-O-methylvisammioside on LPS-induced depression in mice by inhibiting the over activation of BV-2 microglia through Nf-κB/IκB-α pathway(2020/9/19)
作者:Xialin Sun, Tingwen Zhang, Yan Zhao
期刊:Phytomedicine
DOI:10.1016/j.phymed.2020.153348
影响因子 :5.34
引用产品:CL-0493
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Mafenide derivatives inhibit neuroinflammation in Alzheimers disease by regulating pyroptosis(2021/10/10)
作者:Chenyang Han, Qiaohong Hu, Anqi Yu
期刊:Journal Of Cellular And Molecular Medicine
影响因子 :5.31
引用产品:CL-0493
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Serum Extracellular Vesicle–Derived miR-124-3p as a Diagnostic and Predictive Marker for Early-Stage Acute Ischemic Stroke(2021/7/1)
作者:Zheng Qi, Yingying Zhao, Yu Su
期刊:Frontiers in Molecular Biosciences
影响因子 :5.246
引用产品:CL-0493
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Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinsons disease(2019.03.14)
作者:Lv R, Du L, Liu X, Zhou F, Zhang Z, Zhang L
期刊:Life Sciences
影响因子 :5.037
引用产品:CL-0493
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Investigation on the mechanism of mafenide in inhibiting pyroptosis and the release of inflammatory factors(2020.04.30)
作者:Chenyang Han, Yi Yang, Anqi Yu
期刊:European Journal of Pharmaceutical Sciences
DOI:10.1016/j.ejps.2020.105303
影响因子 :4.384
引用产品:CL-0493
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A Causal Relationship in Spinal Cord Injury Rat Model Between Microglia Activation and EGFR/MAPK Detected by Overexpression of MicroRNA-325-3p(25 March 2019)
作者:Penghui Yan, Xuejian Wu, Xiaokang Liu, Yingchun Cai
期刊:Journal of Molecular Neuroscience
DOI:10.1007/s12031-019-01297-w
影响因子 :3.444
引用产品:CL-0493
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Comprehensive analysis of the differential expression profile of microRNAs in rats with spinal cord injury treated by electroacupuncture(May 20, 2020)
作者:Zhidong Zhou, Hejian Li, Hongchun Li
期刊:Molecular Medicine Reports
影响因子 :2.952
引用产品:CL-0493