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产品概述
Dulbecco's 改良培养基--DMEM（Dulbecco's Modified Eagle Medium）是在MEM培养基的基础上研制的，与MEM培养基相比，氨基酸的含量增加了2倍，维生素增加了4倍，同时还增加了非必须氨基酸、微量铁离子以及丙酮酸钠。DMEM培养基最初设计葡萄糖含量为1000mg/L（低糖型），后来又发展出葡萄糖含量为4500mg/L（高糖型），现已广泛应用于各种细胞的培养，不含葡萄糖的DMEM培养基可以根据研究需要，随意调节葡萄糖的浓度，方便快捷。
本产品含有多类细胞培养所需的氨基酸、维生素、无机盐等多种成分，但不含蛋白质、脂类或任何生长因子，故此产品需搭配血清或无血清添加物使用。
成分说明
形态 | 液体 |
浓度 | 1× |
规格 | 500mL |
PH | 7.2～7.4 |
L-谷氨酰胺 | 4mM |
NaHCO3 | 3700mg/L |
D-葡萄糖 | 无 |
丙酮酸钠 | 1mM |
HEPES缓冲剂 | 无 |
酚红指示剂 | 15mg/L |
储存条件 | 2～8℃，避光 |
运输条件 | 常温 |
有效期 | 12个月 |
注意事项
1、本产品经过滤除菌，使用时应注意无菌操作，避免污染；
2、为保持本产品的最佳使用效果，请勿进行冻融处理；
3、本产品仅用于科研或进一步研究使用，不用于诊断和治疗。
参考文献
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Polyphenolic Oligomer-Derived Multienzyme Activity for Treatment of Ischemic Stroke through ROS Scavenging and Blood-Brain Barrier Restoration(2024/01/24)
作者：Wei Meng, Zhifang Ma, Hongbo Ye
期刊：Journal of Materials Chemistry B
影响因子 ：7.000
引用产品：PM150270
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Prenylated flavonoid fractions from Glycyrrhiza glabra alleviate insulin resistance in HepG2 cells by regulating the ERK/IRS-1 and PI3K/Akt signaling pathways(2024/01/24)
作者：Defeng Li, Jinling Fan, Lin Du
期刊：ARCHIVES OF PHARMACAL RESEARCH
DOI：10.1007/s12272-024-01485-2
影响因子 ：6.700
引用产品：PM150270
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Long non-coding RNA UCA1 relieves cardiomyocytes H9c2 injury aroused by oxygen-glucose deprivation via declining miR-122(2019/8/21)
作者：Zaiwei Zhang, Hu Li, Zhiyuan Cui
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1652630
影响因子 ：5.800
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Inhibition of PDE1-B by Vinpocetine Regulates Microglial Exosomes and Polarization Through Enhancing Autophagic Flux for Neuroprotection Against Ischemic Stroke(2021/02/04)
作者：Jiankun Zang, Yousheng Wu, Xuanlin Su
期刊：Frontiers in Cell and Developmental Biology
影响因子 ：5.500
引用产品：PM150270
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Neutral polysaccharide from Gastrodia elata alleviates cerebral ischemia–reperfusion injury by inhibiting ferroptosis-mediated neuroinflammation via the NRF2/HO-1 signaling pathway(2023/09/26)
作者：Yonggang Zhang, Peng Ye, Hua Zhu
期刊：CNS Neuroscience & Therapeutics
影响因子 ：5.500
引用产品：PM150270
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Pharmacological preconditioning by TERT inhibitor BIBR1532 confers neuronal ischemic tolerance through TERT-mediated transcriptional reprogramming(2021/10/09)
作者：Xuemin Xie, Mingxi Li, Mengyao Zhou
期刊：Journal Of Neurochemistry
影响因子 ：4.700
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Oxysophoridine protects against cerebral ischemia/reperfusion injury via inhibition of TLR4/p38MAPK‑mediated ferroptosis(2023/01/04)
作者：Jing Zhao, Mingming Ma, Lei Li
期刊：Molecular Medicine Reports
影响因子 ：3.400
引用产品：PM150270
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Targeting Microglia/Macrophages Notch1 Protects Neurons from Pyroptosis in Ischemic Stroke(2023/11/29)
作者：Ran Chen, Hua Zhu, Zhihui Wang
期刊：Brain Sciences
影响因子 ：3.300
引用产品：PM150270
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MiR-140-5p upregulation suppressed β-glycerophosphate-induced vascular smooth muscle cell calcification via targeting TLR4(2022/03/11)
作者：Fan Zhang,Jingxing Li,Chengxiong Gu
期刊：Immunopharmacology And Immunotoxicology
DOI：10.1080/08923973.2022.2043896
影响因子 ：3.300
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Fructose aggravates copper-deficiency-induced cardiac remodeling by inhibiting SERCA2a(2024/01/25)
作者：Yi Xu, Qiuxia Xu, Zhirui Zheng
期刊：JOURNAL OF PHARMACY AND PHARMACOLOGY
影响因子 ：3.300
引用产品：PM150270
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Protective effect of cornuside on OGD/R injury in SH-SY5Y cells and its underlying mechanism(2023/09/16)
作者：Xinyu Wang, Chao Yan, Chaoyun Wang
期刊：BRAIN RESEARCH
DOI：10.1016/j.brainres.2023.148585
影响因子 ：2.900
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Exosome-shuttled MYCBPAP from bone marrow mesenchymal stem cells regulates synaptic remodeling and ameliorates ischemic stroke in rats(2023/07/07)
作者：Qiuyue Yan, Yong Yin, Xuechun Li
期刊：JOURNAL OF CHEMICAL NEUROANATOMY
DOI：10.1016/j.jchemneu.2023.102309
影响因子 ：2.800
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Inhibition of perilipin 2 attenuates cerebral ischemia/reperfusion injury by blocking NLRP3 inflammasome activation both in vivo and in vitro(2023/04/03)
作者：Xuying Liu, Qiushi Li, Wenhai Yang
期刊：IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
DOI：10.1007/s11626-023-00759-1
影响因子 ：2.100
引用产品：PM150270
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LncRNA Taurine Up-Regulated 1 plays a proapoptotic role by regulating nuclear-cytoplasmic shuttle of HuR under the condition of neuronal ischemia(2022/10/27)
作者：Xiaocheng Shi, Wei Wei, Yichun Zou
期刊：NEUROREPORT
DOI：10.1097/WNR.0000000000001848
影响因子 ：1.700
