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当前位置:首页 >> 产品中心 >> 辅助试剂 >> 细胞因子 >> Human

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  • Procell-IL-10RB/ IL-10R2, Human, Recombinant

IL-10RB/ IL-10R2, Human, Recombinant

货号:PCK168

价格:¥780¥1880¥7880¥9980

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +
产品概述

产品信息

别名 Interleukin-10 Receptor subunit beta (IL10RB); Cytokine Receptor class-II member 4; Cytokine Receptor family 2 member 4; Interleukin-10 Receptor subunit 2
物种 Human
表达宿主 Human Cells
序列信息 Met20-Ser220
检索号 NP_000619.3
分子量 24.5 kDa
表观分子量 48 kDa
标签 C-6His
生物活性 Testing in progress

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized Protein should be stored at < -20℃, though stable at room temperature for 3 weeks. Reconstituted Protein solution can be stored at 4-7℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
运输 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
制剂 Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

IL10RB is a single- pass type I membrane Protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active Interleukin 10 Receptor complex. Coexpression of IL10RB and IL10RA Proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
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