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产品概述
名称 | ACHN (人肾细胞腺癌细胞) (STR鉴定正确) |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
生长培养基 | MEM(含NEAA)+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:2-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | 人干扰素可抑制ACHN细胞生长;ACHN细胞能用于人干扰素、干扰素诱导因子的抗肿瘤活性研究。 |
年龄(性别) | 男;22岁 |
组织来源 | 肾细胞腺癌,胸水转移灶 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肾癌细胞 |
生物安全等级 | 1 |
倍增时间 | ~28-36 hours |
致瘤性 | Yes, in nude mice (Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells). |
保藏机构 | ATCC; CRL-1611 ECACC; 88100508 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11 D2S1338 17 D3S1358 17 D5S818 12 D7S820 9,11 D8S1179 12 D13S317 12 D16S539 12,13 D18S51 16 D19S433 14,15 D21S11 30 FGA 22 PentaD 12 PentaE 16 TH01 8 TPOX 8,11 vWA 16,17 D6S1043 11 D12S391 19,22 D2S441 11,14 -
STR鉴定图
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参考文献
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The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors(2022/04/02)
作者:Liu Wentao, Zhang Bin, Zhang Dan
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-04760-6
影响因子 :9.000
引用产品:CL-0005 CL-0010 CL-0021 PB180120 PM150110 PM150210 PM150410
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Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming(2023/02/20)
作者:Zhangnan Liu, Mengzhen Fan, Junqing Hou
期刊:Cell Death & Disease
DOI:10.1038/s41419-023-05677-4
影响因子 :9.000
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Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer(2022/11/17)
作者:Ren, Jiannan, Yu, Haixin, Li, Wei, Jin, Xin, Yan, Bin
期刊:BRITISH JOURNAL OF CANCER
DOI:10.1038/s41416-022-02058-0
影响因子 :8.800
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Prognostic and tumor microenvironmental feature of clear cell renal cell carcinoma revealed by m6A and lactylation modification-related genes(2023/08/11)
作者:Lin Yang, Xiaoyu Wang, Jiahao Liu
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1225023
影响因子 :7.300
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RETRACTED ARTICLE: Silencing circular RNA-ZNF652 represses proliferation and EMT process of renal carcinoma cells via raising miR-205(2020/2/19)
作者:Ludong Zhang, Ya Guo
期刊:Artificial Cells Nanomedicine and Biotechnology
DOI:10.1080/21691401.2020.1725532
影响因子 :5.800
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HOXD8 suppresses renal cell carcinoma growth by upregulating SHMT1 expression(2023/09/26)
作者:Yang Yang, Minghui Zhang, Yaxuan Zhao
期刊:CANCER SCIENCE
影响因子 :5.700
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Root extract of Hemsleya amabilis Diels suppresses renal cell carcinoma cell growth through inducing apoptosis and G2/M phase arrest via PI3K/AKT signaling pathway activation(2023/08/07)
作者:Kai Li, Ganhua You, Kehua Jiang, Rongpin Wang, Wuchao Li, Yonglu Meng, Yinyi Fang, Weiming Chen, Guohua Zhu, Jukun Song, Wei Wang, Hao Su, Bin Hu, Fa Sun, Zhenyu Jia, Can Li, Jianguo Zhu
期刊:JOURNAL OF ETHNOPHARMACOLOGY
影响因子 :5.400
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The mechanism of long-chain acyl-CoA synthetase 3 in inhibiting cell proliferation, migration, and invasion in clear cell renal cell carcinoma(2023/03/15)
作者:Lin Zhang, Bo Wu, Dongwen Wang
期刊:American Journal of Cancer Research
DOI:PMID:37034217
影响因子 :5.300
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LncRNA-encoded Micropeptide ACLY-BP drives lipid deposition and cell proliferation in Clear Cell Renal Cell Carcinoma via maintenance of ACLY acetylation(2023/07/06)
作者:Shenghua Zhang, Zheng Zhang, Xiaolong Liu
期刊:MOLECULAR CANCER RESEARCH
DOI:10.1158/1541-7786.MCR-22-0781
影响因子 :5.200
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AKG induces cell apoptosis by inducing reactive oxygen species-mediated endoplasmic reticulum stress and by suppressing PI3K/AKT/mTOR-mediated autophagy in renal cell carcinoma(2022/09/16)
作者:Fan Wu, Xuexia Xie, Guoliang Li
期刊:ENVIRONMENTAL TOXICOLOGY
影响因子 :4.500
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma(2019/05/21)
作者:Jin Wang, Chao Tang, Chao Yang
期刊:J Cancer
影响因子 :4.478
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GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling(2023/01/20)
作者:Shujiang Ye, Siyu Li, Lei Qin
期刊:ONCOLOGY REPORTS
影响因子 :4.200
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δ‐Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β‐catenin nuclear localization and activating its downstream target genes(2020/01/28)
作者:Lincheng Ju, Liping Shan, Bo Yin
期刊:Cancer Medicine
影响因子 :4.000
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TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT(2020/3/4)
作者:Mengya Zhong, Maoshu Zhu, Yu Liu
期刊:Journal of Cancer
影响因子 :3.900
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma(2019/5/21)
作者:Jin Wang, Chao Tang, Chao Yang
期刊:Journal of Cancer
影响因子 :3.900
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Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma(2022/08/09)
作者:Xiao Liu, Meng Jiang, Chenggang Pang
期刊:BMC CANCER
DOI:10.1186/s12885-022-09965-8
影响因子 :3.800
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The potential of Lycium barbarum miR166a in kidney cancer treatment(2022/12/28)
作者:Qiang Zhang, Zhiyuan Xie, Yan Li
期刊:EXPERIMENTAL CELL RESEARCH
DOI:10.1016/j.yexcr.2022.113455
影响因子 :3.700
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P4HA3 promotes clear cell renal cell carcinoma progression via the PI3K/AKT/GSK3β pathway(2023/01/02)
作者:Zhechuan Zhang, Yuanfeng Zhang, Ronggui Zhang
期刊:MEDICAL ONCOLOGY
DOI:10.1007/s12032-022-01926-2
影响因子 :3.400
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Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma(2018/3/7)
作者:Chao Tang, Jin Wang, Qi Wei
期刊:Oncology Letters
影响因子 :2.900
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Identification of a combined lncRNA prognostic signature and knockdown of lncRNA MANCR to inhibit progression of clear cell renal cell carcinoma by bioinformatics analysis(2022/09/01)
作者:Sheng Xue, Hanxu Guo, Shibo Wei
期刊:Translational Andrology and Urology
影响因子 :2.000
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Pachymic Acid Inhibits the Migration and Epithelial–Mesenchymal Transition of Renal Cell Carcinoma(2022/10/17)
作者:Yuanyuan Luo, Zewen Chu, Zhefeng Wang
期刊:Natural Product Communications
影响因子 :1.800
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Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression(2022/11/30)
作者:Liqing Yang, Lin Wang, Jitao Wu, Yongqiang Wang
期刊:TRANSPLANT IMMUNOLOGY
DOI:10.1016/j.trim.2022.101764
影响因子 :1.500