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产品概述
| 名称 | ACHN (人肾细胞腺癌细胞) (STR鉴定正确) |
| 背景描述 | 人干扰素可抑制ACHN细胞生长；ACHN细胞能用于人干扰素、干扰素诱导因子的抗肿瘤活性研究。 |
| 种属 | 人 |
| 年龄（性别） | 男；22岁 |
| 组织来源 | 肾细胞腺癌，胸水转移灶 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肾癌细胞 |
| 生物安全等级 | 1 |
| 生长培养基 | MEM＋10% FBS＋1% P/S |
| 推荐传代比例 | 1:2-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 倍增时间 | ~28-36 hours |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 致瘤性 | Yes, in nude mice (Tumors developed within 21 days at 100% frequency (5/5) in nude mice inoculated subcutaneously with 1×10^7 cells). |
| 保藏机构 | ATCC; CRL-1611 ECACC; 88100508 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 11 D2S1338 17 D3S1358 17 D5S818 12 D7S820 9,11 D8S1179 12 D13S317 12 D16S539 12,13 D18S51 16 D19S433 13,14,15,16.2 D21S11 30 FGA 22 PentaD 12 PentaE 16 TH01 8 TPOX 8,11 vWA 16,17 D6S1043 11 D12S391 19,22 D2S441 11,14 -
STR鉴定图
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参考文献
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The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors(2022/04/02)
作者：Liu Wentao, Zhang Bin, Zhang Dan
期刊：Cell Death & Disease
DOI：10.1038/s41419-022-04760-6
影响因子 ：9.6850
引用产品：CL-0005 CL-0010 CL-0021 PB180120 PM150110 PM150210 PM150410
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Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer(2022/11/17)
作者：Ren, Jiannan, Yu, Haixin, Li, Wei, Jin, Xin, Yan, Bin
期刊：BRITISH JOURNAL OF CANCER
DOI：10.1038/s41416-022-02058-0
影响因子 ：9.0750
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RETRACTED ARTICLE: Silencing circular RNA-ZNF652 represses proliferation and EMT process of renal carcinoma cells via raising miR-205(2020/2/19)
作者：Ludong Zhang, Ya Guo
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2020.1725532
影响因子 ：6.3550
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δ‐Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β‐catenin nuclear localization and activating its downstream target genes(2020/01/28)
作者：Lincheng Ju, Liping Shan, Bo Yin
期刊：Cancer Medicine
影响因子 ：4.711
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Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma(2022/08/09)
作者：Xiao Liu, Meng Jiang, Chenggang Pang
期刊：BMC CANCER
DOI：10.1186/s12885-022-09965-8
影响因子 ：4.6380
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma(2019/05/21)
作者：Jin Wang, Chao Tang, Chao Yang
期刊：J Cancer
影响因子 ：4.478
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TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT(2020/3/4)
作者：Mengya Zhong, Maoshu Zhu, Yu Liu
期刊：Journal of Cancer
影响因子 ：4.2070
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Tropomyosin-1 Functions as a Tumor Suppressor with Respect to Cell Proliferation, Angiogenesis and Metastasis in Renal Cell Carcinoma(2019/5/21)
作者：Jin Wang, Chao Tang, Chao Yang
期刊：Journal of Cancer
影响因子 ：4.2070
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AKG induces cell apoptosis by inducing reactive oxygen species-mediated endoplasmic reticulum stress and by suppressing PI3K/AKT/mTOR-mediated autophagy in renal cell carcinoma(2022/09/16)
作者：Fan Wu, Xuexia Xie, Guoliang Li
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.1090
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Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma(2018/3/7)
作者：Chao Tang, Jin Wang, Qi Wei
期刊：Oncology Letters
影响因子 ：3.1110
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Identification of a combined lncRNA prognostic signature and knockdown of lncRNA MANCR to inhibit progression of clear cell renal cell carcinoma by bioinformatics analysis(2022/09/01)
作者：Sheng Xue, Hanxu Guo, Shibo Wei
期刊：Translational Andrology and Urology
影响因子 ：2.4790
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Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression(2022/11/30)
作者：Liqing Yang, Lin Wang, Jitao Wu, Yongqiang Wang
期刊：TRANSPLANT IMMUNOLOGY
DOI：10.1016/j.trim.2022.101764
影响因子 ：2.0320
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Pachymic Acid Inhibits the Migration and Epithelial–Mesenchymal Transition of Renal Cell Carcinoma(2022/10/17)
作者：Yuanyuan Luo, Zewen Chu, Zhefeng Wang
期刊：Natural Product Communications
影响因子 ：1.4960
