本司产品仅用于科研,不用于临床诊断和治疗

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  • McCoy's 5A
  • McCoy's 5A

McCoy's 5A

货号:PM150710

规格:500mL

价格: ¥98

数量: - +
  • McCoy's 5A
  • McCoy's 5A
产品概述

McCoy's 5A培养基是Thomas McCoy等人在1959年设计的培养基,最初专门用于Novikoff Hepatoma细胞的培养。McCoy's 5A培养基是改良的Basal Medium 5A,与其他培养基不同的是,McCoy's 5A含有还原型谷胱甘肽、细菌蛋白胨以及高浓度的葡萄糖。McCoy's 5A广泛用于多种类型的原代细胞的培养,如骨髓、皮肤、牙龈、肾、脾、肺、大鼠胚胎、网膜等。此外McCoy's 5A培养基还用于组织活检培养、细胞建系,以及一些淋巴细胞和较难培养的细胞的培养。

本产品含有多类细胞培养所需的氨基酸、维生素、无机盐等多种成分,但不含蛋白质、脂类或任何生长因子,故此产品需搭配血清或无血清添加物使用。

成分说明

形态

液体

浓度

规格

500mL

PH

7.27.4

L-谷氨酰胺

1.5mM

NaHCO3

2200mg/L

D-葡萄糖

3000mg/L

HEPES缓冲剂

酚红指示剂

10mg/L

储存条件

28,避光

运输条件

常温

有效期

12个月

注意事项

1、本产品经过滤除菌,使用时应注意无菌操作,避免污染;

2、为保持本产品的最佳使用效果,请勿进行冻融处理;

3、本产品仅用于科研或进一步研究使用,不用于诊断和治疗。


参考文献
文献列表
  • Nitroreductase-instructed supramolecular assemblies for microbiome regulation to enhance colorectal cancer treatments(2022/11/09)

    作者:Jiali Chen, Pai Zhang, Yan Zhao, Jie Zhao, Xiaobo Wu, Ruijia Zhang, Ruitao Cha, Qingxin Yao, Yuan Gao

    期刊:Science Advances

    DOI:10.1126/sciadv.add2789

    影响因子 :13.600

    引用产品:CL-0071 CL-0096 CL-0101 CL-0118 PM150110 PM150210 PM150710

  • WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity(2023/01/07)

    作者:Xiaosong Wei, Beibei Wang, Zixin Wu

    期刊:CANCER LETTERS

    DOI:10.1016/j.canlet.2023.216058

    影响因子 :9.700

    引用产品:CL-0002 CL-0125 CL-0222 CL-0227 CL-0449A CL-0463 CL-0628 PM150410 PM150710 PM150910 PM151010

  • Biodegradable Magnetic Hydrogel Robot with Multimodal Locomotion for Targeted Cargo Delivery(2023/06/07)

    作者:Xi Chen, Chenyao Tian, Hao Zhang

    期刊:ACS Applied Materials & Interfaces

    DOI:10.1021/acsami.3c02703

    影响因子 :9.500

    引用产品:164210 164210-50 CL-0005 CL-0096 PB180120 PB180327 PM150210 PM150710

  • Dimethyl fumarate inhibits necroptosis and alleviates systemic inflammatory response syndrome by blocking the RIPK1-RIPK3-MLKL axis(2023/02/14)

    作者:Fuli Shi, Lisha Yuan, Taksui Wong

    期刊:PHARMACOLOGICAL RESEARCH

    DOI:10.1016/j.phrs.2023.106697

    影响因子 :9.300

    引用产品:PM150710

  • A possible but unrecognized risk of acceptable daily intake dose triazole pesticides exposure—bile acid disturbance induced pharmacokinetic changes of oral medication(2023/02/21)

    作者:Yujing Xu, Yufeng Zhang, Quan Tao

    期刊:CHEMOSPHERE

    DOI:10.1016/j.chemosphere.2023.138209

    影响因子 :8.800

    引用产品:CL-0118 PM150710

  • Exosomal AP000439.2 from clear cell renal cell carcinoma induces M2 macrophage polarization to promote tumor progression through activation of STAT3(2022/09/24)

    作者:Tianyi Shen, Suqin Miao, Yulin Zhou

    期刊:Cell Communication and Signaling

    DOI:10.1186/s12964-022-00957-6

    影响因子 :8.400

    引用产品:PM150710

  • Mutual regulation between TRIM21 and TRIM8 via K48-linked ubiquitination(2023/11/01)

    作者:Lin Wang, Hui Li, Aixue Huang

    期刊:ONCOGENE

    DOI:10.1038/s41388-023-02879-0

    影响因子 :8.000

    引用产品:PM150710

  • Photothermal Nanoheaters-Modified Spores for Safe and Controllable Antitumor Therapy(2022/12/15)

    作者:Xin Zhang, Yang Zhang, Ning Wang

    期刊:International Journal of Nanomedicine

    DOI:10.2147/IJN.S385269

    影响因子 :8.000

    引用产品:PM150710

  • Isothiocyanate Iberin inhibits cell proliferation and induces cell apoptosis in the progression of ovarian cancer by mediating ROS accumulation and GPX1 expression(2021/06/17)

    作者:Tingting Gong, Qian Guo, Xiao Li

    期刊:Biomedicine & Pharmacotherapy

    DOI:10.1016/j.biopha.2021.111533

    影响因子 :7.500

    引用产品:CL-0178 CL-0215 PM150110 PM150710

  • Novel pyrazolo[3,4-d]pyrimidines as potential anticancer agents: Synthesis, VEGFR-2 inhibition, and mechanisms of action(2022/10/31)

    作者:Zukela Ruzi, Khurshed Bozorov, Lifei Nie

    期刊:BIOMEDICINE & PHARMACOTHERAPY

    DOI:10.1016/j.biopha.2022.113948

    影响因子 :7.500

    引用产品:PM150710

  • Chiral Analysis of Lactate during Direct Contact Coculture by Single-Cell On-Probe Enzymatic Dehydrogenation Derivatization: Unraveling Metabolic Changes Caused by d-Lactate(2021/03/16)

    作者:Yuling Li, Bowen Zhou, Yuqi Cao

    期刊:Analytical Chemistry

    DOI:10.1021/acs.analchem.0c05015

    影响因子 :7.400

    引用产品:PB180327 PM150114 PM150710

  • Aa-Z2 triggers ROS-induced apoptosis of osteosarcoma by targeting PDK-1(2023/01/07)

    作者:Yixin Liu, Wenyan She, Yi Li

    期刊:Journal of Translational Medicine

    DOI:10.1186/s12967-022-03862-1

    影响因子 :7.400

    引用产品:CL-0602 PM150710

  • Combined Molecular and Morphological Imaging of CTCs for HER2-Targeted Chemotherapy Guidance(2023/08/22)

    作者:Haimeng Pei, Zhaojun Han, Dexin Du

    期刊:ANALYTICAL CHEMISTRY

    DOI:10.1021/acs.analchem.3c02333

    影响因子 :7.400

    引用产品:CL-0149 CL-0150B CL-0211 PM150710

  • Chlorophyllin Inhibits Mammalian Thioredoxin Reductase 1 and Triggers Cancer Cell Death(2021/10/29)

    作者:Shibo Sun, Yici Zhang, Weiping Xu

    期刊:Antioxidants

    DOI:10.3390/antiox10111733

    影响因子 :7.000

    引用产品:CL-0096 PM150710

  • Preparation and biological evaluation of antibody targeted metal-organic framework drug delivery system (TDDS) in Her2 receptor-positive cells(2023/11/13)

    作者:Chen Qing, Xiaonan Zhang, Guoyu Ding

    期刊:TALANTA

    DOI:10.1016/j.talanta.2023.125380

    影响因子 :6.100

    引用产品:PM150710

  • High-fat diet alters the radiation tolerance of female mice and the modulatory effect of melatonin(2023/06/19)

    作者:Lu Lu, Jinming Ren, Tong Yuan

    期刊:Food & Function

    DOI:10.1039/D3FO01831H

    影响因子 :6.100

    引用产品:PM150710

  • LncRNA-LET inhibits cell growth of clear cell renal cell carcinoma by regulating miR-373-3p(2019/11/21)

    作者:Zhuo Ye, Jiachen Duan, Lihui Wang

    期刊:Cancer Cell International

    DOI:10.1186/s12935-019-1008-6

    影响因子 :5.800

    引用产品:CL-0005 CL-0009 CL-0010 CL-0052 PM150110 PM150210 PM150710

  • ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p(2020/03/30)

    作者:Quan Yuan, Honghao Yu, Jianhua Chen

    期刊:Cancer Cell International

    DOI:10.1186/s12935-020-01174-2

    影响因子 :5.800

    引用产品:CL-0202 CL-0360 CL-0447A CL-0447B PM150710

  • A1BG-AS1 promotes the biological functions of osteosarcoma cells via regulating the microRNA-148a-3p/USP22 axis and stabilizing the expression of SIRT1 through deubiquitinase function(2023/10/03)

    作者:Xiuxin Han, Mengfan Yin, Chen Gong

    期刊:EXPERT OPINION ON THERAPEUTIC TARGETS

    DOI:10.1080/14728222.2023.2263908

    影响因子 :5.800

    引用产品:PM150710

  • Nigericin exerts anticancer effects through inhibition of the SRC/STAT3/BCL-2 in osteosarcoma(2022/01/31)

    作者:Zhiqiang Yang, Jiangtao Xie, Jiayu Fang

    期刊:Biochemical Pharmacology

    DOI:10.1016/j.bcp.2022.114938

    影响因子 :5.800

    引用产品:PM150710

  • Celastrol inhibits necroptosis by attenuating the RIPK1/RIPK3/MLKL pathway and confers protection against acute pancreatitis in mice(2023/03/08)

    作者:Qiqi Liang, Zijian Shi, Tao Yuan

    期刊:INTERNATIONAL IMMUNOPHARMACOLOGY

    DOI:10.1016/j.intimp.2023.109974

    影响因子 :5.600

    引用产品:PM150710

  • IGF2BP2 promotes colorectal cancer progression by upregulating the expression of TFRC and enhancing iron metabolism(2023/04/23)

    作者:Tianyue Liu, Chenchen Hu, Chenying Han

    期刊:Biology Direct

    DOI:10.1186/s13062-023-00373-x

    影响因子 :5.500

    引用产品:PM150710

  • A Moexitecan Magnetic Liposomal Strategy for Ferroptosis-Enhanced Chemotherapy(2023/07/24)

    作者:Weiling Miao, Yang Liu, Jian Tang

    期刊:Pharmaceutics

    DOI:10.3390/pharmaceutics15072012

    影响因子 :5.400

    引用产品:CL-0103 CL-0118 CL-0185 PM150410 PM150710 PM150910

  • PYY modulates the tumorigenesis and progression of colorectal cancer unveiled by proteomics(2022/12/15)

    作者:Fangyan Jing, Guanglong Liu, Renyi Zhang

    期刊:American Journal of Cancer Research

    DOI:PMID:36628274

    影响因子 :5.300

    引用产品:PM150710

  • Comprehensive Pan-Cancer Analyses of Immunogenic Cell Death as a Biomarker in Predicting Prognosis and Therapeutic Response(2022/12/01)

    作者:Yuan Wang, Yongbiao Huang, Mu Yang

    期刊:Cancers

    DOI:10.3390/cancers14235952

    影响因子 :5.200

    引用产品:PM150710

  • Discovery of novel (E)-1-methyl-9-(3-methylbenzylidene)-6,7,8,9-tetrahydropyrazolo[3,4-d]pyrido[1,2-a]pyrimidin-4(1H)-one as DDR2 kinase inhibitor: Synthesis, molecular docking, and anticancer properties(2023/04/03)

    作者:Zukela Ruzi, Khurshed Bozorov, Lifei Nie

    期刊:BIOORGANIC CHEMISTRY

    DOI:10.1016/j.bioorg.2023.106506

    影响因子 :5.100

    引用产品:PM150710

  • Synthesis and anticancer activity of ethyl 5-amino-1-N-substituted-imidazole-4-carboxylate building blocks(2021/05/25)

    作者:Zukela Ruzi, Lifei Nie, Khurshed Bozorov

    期刊:Archiv Der Pharmazie

    DOI:10.1002/ardp.202000470

    影响因子 :5.100

    引用产品:PM150710

  • Anti-Necroptotic Effects of Itaconate and its Derivatives(2023/09/27)

    作者:Sitao Ni, Qing Li, Ying Chen

    期刊:INFLAMMATION

    DOI:10.1007/s10753-023-01909-z

    影响因子 :5.100

    引用产品:PM150710

  • Multiscale Magnetic Hydrogel Robot with a Core–Shell Structure for Active Targeted Delivery(2022/10/25)

    作者:Xi Chen, Hao Zhang, Chenyao Tian

    期刊:ACS Applied Polymer Materials

    DOI:10.1021/acsapm.2c01555

    影响因子 :5.000

    引用产品:164210 164210-50 CL-0005 CL-0096 PB180120 PM150210 PM150710

  • NPR3, transcriptionally regulated by POU2F1, inhibits osteosarcoma cell growth through blocking the PI3K/AKT pathway(2021/7/3)

    作者:Shuo Li, Ruirong Guo, Zhibin Peng

    期刊:Cellular Signalling

    DOI:10.1016/j.cellsig.2021.110074

    影响因子 :4.800

    引用产品:PM150710

  • LAMA5 promotes cell proliferation and migration in ovarian cancer by activating Notch signaling pathway(2023/08/01)

    作者:Bowen Diao, Chongfeng Sun, Panpan Yu

    期刊:FASEB JOURNAL

    DOI:10.1096/fj.202300306R

    影响因子 :4.800

    引用产品:PM150710

  • TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy(2023/03/18)

    作者:Tanjing Song, Suli Lv, Xianyun Ma

    期刊:JOURNAL OF BIOLOGICAL CHEMISTRY

    DOI:10.1016/j.jbc.2023.104621

    影响因子 :4.800

    引用产品:CM-0568 PM150110 PM150210 PM150410 PM150710

  • Upregulated X-C motif chemokine ligand 2 (XCL2) is associated with poor prognosis and increased immune infiltration in clear cell renal cell carcinoma(2022/12/09)

    作者:Qingqiong Cao, Daoquan Liu, Zhao Chen

    期刊:CELLULAR SIGNALLING

    DOI:10.1016/j.cellsig.2022.110556

    影响因子 :4.800

    引用产品:PM150710

  • Exosomal lncRNA NEAT1 from cancer-associated fibroblasts facilitates endometrial cancer progression via miR-26a/b-5p-mediated STAT3/YKL-40 signaling pathway(2021/06/18)

    作者:Jiangtao Fan, Zhaoyu Zhou, Yanlu Luo

    期刊:Neoplasia

    DOI:10.1016/j.neo.2021.05.004

    影响因子 :4.800

    引用产品:CP-H058 PM150312 PM150410P PM150710

  • The ubiquitin E3 ligase MDM2 induces chemoresistance in colorectal cancer by degradation of ING3(2023/06/06)

    作者:Liangliang Zhang, Dagang Zhu, Jiwen Jiang

    期刊:CARCINOGENESIS

    DOI:10.1093/carcin/bgad040

    影响因子 :4.700

    引用产品:164210 CL-0096 PB180120 PM150410 PM150710

  • ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop(2023/06/16)

    作者:Sijia Han, Xueying Jin, Tianyu Hu

    期刊:CARCINOGENESIS

    DOI:10.1093/carcin/bgad042

    影响因子 :4.700

    引用产品:CL-0211 CL-0228 PM150710 PM151010

  • A ferroptosis-related gene signature associated with immune landscape and therapeutic response in osteosarcoma.(2022/11/11)

    作者:Xinxing Wang, Guang Xia, Shilang Xiao, Song Wu, Lina Zhang, Junjie Huang, Wenxiu Zhang, Xu Cao, Image_1.tif, Image_2.tif, Image_3.tif, Image_4.tif, Image_5.tif, Image_6.tif, Image_7.tif, DataSheet_1.csv, DataSheet_2.csv, DataSheet_3.csv, DataSheet_4.

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2022.1024915

    影响因子 :4.700

    引用产品:CL-0236 CL-0492 PM150411 PM150710

  • Copine 7 promotes colorectal cancer proliferation through PKM2 interaction and MAPK signaling pathway(2023/07/04)

    作者:Tianwen Yu, Changhao Huang, Chen Lai

    期刊:Frontiers in Oncology

    DOI:10.3389/fonc.2023.1166444

    影响因子 :4.700

    引用产品:164210 164210-50 CL-0001 CL-0074 CL-0096 PM150110 PM150210 PM150710

  • MMP9 and TYROBP affect the survival of circulating tumor cells in clear cell renal cell carcinoma by adapting to tumor immune microenvironment(2023/04/28)

    作者:Lingyu Guo, Tian An, Haibin Zhou

    期刊:Scientific Reports

    DOI:10.1038/s41598-023-34317-2

    影响因子 :4.600

    引用产品:PM150710

  • A Novel Cuproptosis-Related Prognostic Model and the Hub Gene FDX1 Predict the Prognosis and Correlate with Immune Infiltration in Clear Cell Renal Cell Carcinoma(2022/12/10)

    作者:Kenan Zhang, Wuping Yang, Zedan Zhang

    期刊:Journal of Oncology

    DOI:10.1155/2022/2124088

    影响因子 :4.501

    引用产品:PM150110 PM150210 PM150710

  • Up-Regulation of SH3TC2 Induced by YTHDF1 Predicts Poor Outcome and Facilitates Cell-Cycle Progress in Colorectal Cancer(2022/12/15)

    作者:Huili Wu, Feifei Chu, Lu Li

    期刊:Journal of Oncology

    DOI:10.1155/2022/1600611

    影响因子 :4.501

    引用产品:CL-0096 PM150510 PM150710

  • Fatty Acid–Binding Protein 4 (FABP4) Suppresses Proliferation and Migration of Endometrial Cancer Cells via PI3K/Akt Pathway(2021/06/29)

    作者:Zimeng Wu, Ji-Hak Jeong, Chenchen Ren

    期刊:OncoTargets and Therapy

    DOI:10.2147/OTT.S311792

    影响因子 :4.345

    引用产品:CL-0133 PM150710

  • MiR-519d and miR-328-3p Combinatorially Suppress Breast Cancer Progression(2020/12/18)

    作者:Haiming Ma, Tao Liu, Yanhua Xu

    期刊:OncoTargets and Therapy

    DOI:10.2147/OTT.S281962

    影响因子 :4.345

    引用产品:164210 PB180120 PB180432 PM150312 PM150410 PM150710 PM151010

  • OSU-03012 Disrupts Akt Signaling and Prevents Endometrial Carcinoma Progression in vitro and in vivo(2021/04/30)

    作者:Leilei Ding, Chenchen Ren, Li Yang

    期刊:Drug Design Development and Therapy

    DOI:10.2147/DDDT.S304128

    影响因子 :4.319

    引用产品:CL-0133 PM150710

  • The induction of ferroptosis by KLF11/NCOA4 axis: the inhibitory role in clear cell renal cell carcinoma(2023/08/29)

    作者:Ziqi Zhou, Xi Lv, Shibo Liu

    期刊:Human Cell

    DOI:10.1007/s13577-023-00973-9

    影响因子 :4.300

    引用产品:CL-0009 CL-0109 PM150710

  • Odd-skipped related 1 plays a tumor suppressor role in ovarian cancer via promoting follistatin-like protein 1 transcription(2022/08/14)

    作者:Yu Zhong, Ouyang Ling

    期刊:Human Cell

    DOI:10.1007/s13577-022-00767-5

    影响因子 :4.300

    引用产品:PM150710

  • Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer(2022/08/02)

    作者:Bo Zhang, Wenbin Cao, Yang Liu

    期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY

    DOI:10.1007/s11010-022-04525-x

    影响因子 :4.300

    引用产品:164210 164210-50 CL-0096 CL-0144 PM150710 PM151010

  • Long non‑coding RNA BLACAT2/miR‑378a‑3p/YY1 feedback loop promotes the proliferation, migration and invasion of uterine corpus endometrial carcinoma(2023/04/13)

    作者:Chen Zhang, Ruicong Wang, Mengyuan Li

    期刊:ONCOLOGY REPORTS

    DOI:10.3892/or.2023.8544

    影响因子 :4.200

    引用产品:PM150312 PM150710

  • NONHSAG028908.3 sponges miR‑34a‑5p to promote growth of colorectal cancer via targeting ALDOA(2023/03/15)

    作者:Chuanzhuo Wang, He Xin, Guangxin Yan

    期刊:ONCOLOGY REPORTS

    DOI:10.3892/or.2023.8526

    影响因子 :4.200

    引用产品:CL-0050 CL-0096 CL-0144 CP-H040 PM150710 PM150910

  • GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling(2023/01/20)

    作者:Shujiang Ye, Siyu Li, Lei Qin

    期刊:ONCOLOGY REPORTS

    DOI:10.3892/or.2023.8486

    影响因子 :4.200

    引用产品:CL-0010 CL-0021 PM150710

  • LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway(2023/02/10)

    作者:Sijia Han, Xueying Jin, Tianyu Hu, Feng Chi

    期刊:ONCOLOGY REPORTS

    DOI:10.3892/or.2023.8497

    影响因子 :4.200

    引用产品:CL-0211 CL-0228 PM150710 PM151010

  • Long-Lasting Proteinaceous Nanoformulation for Tumor Imaging and Therapy(2022/08/24)

    作者:Lai Zhao, Xinquan Gu, Fuquan Jiang

    期刊:ACS Omega

    DOI:10.1021/acsomega.2c03561

    影响因子 :4.100

    引用产品:CL-0431 PM150710

  • Synthesis and Antitumor Activities of Novel Mitochondria-Targeted Dihydroartemisinin Ether Derivatives(2022/10/18)

    作者:Cangcang Xu, Linfan Xiao, Peiyu Lin

    期刊:ACS Omega

    DOI:10.1021/acsomega.2c04562

    影响因子 :4.100

    引用产品:164210 164210-50 PM150110 PM150411 PM150710

  • Identification of an EMT-related gene-based prognostic signature in osteosarcoma(2023/04/27)

    作者:Haoli Gong, Ye Tao, Sheng Xiao

    期刊:Cancer Medicine

    DOI:10.1002/cam4.5942

    影响因子 :4.000

    引用产品:CL-0236 CL-0492 PM150411 PM150710

  • Circular RNA circ_0007142 Facilitates Colorectal Cancer Progression by Modulating CDC25A Expression via miR-122-5p(2020/5/1)

    作者:Wenzhe Yin, Jun Xu, Chao Li

    期刊:OncoTargets and Therapy

    DOI:10.2147/OTT.S238338

    影响因子 :4.000

    引用产品:PM150710

  • UBP43 promotes epithelial ovarian carcinogenesis via activation of β-catenin signaling pathway(2023/04/26)

    作者:Hongyang Xie, Junyu Chen, Changyan Ma

    期刊:CELL BIOLOGY INTERNATIONAL

    DOI:10.1002/cbin.12028

    影响因子 :3.900

    引用产品:CM-0653 PM150710

  • Anti-colorectal cancer of Ardisia gigantifolia Stapf. and targets prediction via network pharmacology and molecular docking study(2023/01/09)

    作者:Weibo Dai, Jing Yang, Xin Liu

    期刊:BMC Complementary Medicine and Therapies

    DOI:10.1186/s12906-022-03822-8

    影响因子 :3.900

    引用产品:PM150710

  • FDX1 expression predicts favourable prognosis in clear cell renal cell carcinoma identified by bioinformatics and tissue microarray analysis(2022/09/16)

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