本司产品仅用于科研,不用于临床诊断和治疗

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  • Leibovitz's L-15
  • Leibovitz's L-15

Leibovitz's L-15

货号:PM151010

规格:500mL

价格: ¥160

数量: - +
  • Leibovitz's L-15
  • Leibovitz's L-15
产品概述

Leibovitz's L-15培养基的缓冲系统由磷酸盐和游离碱基氨基酸组成,代替了传统的碳酸氢钠缓冲系统,同时,用半乳糖和丙酮酸钠代替葡萄糖可以防止酸性代谢副产物的形成,有助于维持培养液PH的稳定,适合用于非CO2平衡环境的细胞培养。Leibovitz's L-15培养基适用于猴肾细胞和HEP-2的培养、原代(如胚胎和成人组织)细胞分离、多种病毒的培养以及神经元的培养等。

本产品含有多类细胞培养所需的氨基酸、维生素、无机盐等多种成分,但不含蛋白质、脂类或任何生长因子,故此产品需搭配血清或无血清添加物使用。

成分说明

形态

液体

浓度

规格

500mL

PH

7.27.4

缓冲系统

磷酸盐、氨基酸缓冲系统

L-谷氨酰胺

300mg/L

NaHCO3

D-葡萄糖

D-半乳糖

900mg/L

丙酮酸钠

550mg/L

HEPES缓冲剂

酚红指示剂

10mg/L

储存条件

28,避光

运输条件

常温

有效期

12个月

注意事项

1、本产品经过滤除菌,使用时应注意无菌操作,避免污染;

2、本品不适用于CO2环境,CO2会导致培养液PH降低(培养液变黄),严重影响细胞生长;

3、为保持本产品的最佳使用效果,请勿进行冻融处理;

4、本产品仅用于科研或进一步研究使用,不用于诊断和治疗。


参考文献
文献列表
  • In vivo imaging of mitochondrial DNA mutations using an integrated nano Cas12a sensor(2023/11/24)

    作者:Yanan Li, Yonghua Wu, Ru Xu

    期刊:Nature Communications

    DOI:10.1038/s41467-023-43552-0

    影响因子 :16.600

    引用产品:PM151010

  • Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer(2023/04/02)

    作者:Yan Guo, Yuqing Cui, Yangyang Li

    期刊:Cancer Communications

    DOI:10.1002/cac2.12417

    影响因子 :16.200

    引用产品:CM-0525 PB180337 PM151010

  • Circ-MBOAT2 knockdown represses tumor progression and glutamine catabolism by miR-433-3p/GOT1 axis in pancreatic cancer(2021/04/08)

    作者:Zhou Xiaoxiao, Liu Kun, Cui Jing

    期刊:Journal of Experimental & Clinical Cancer Research

    DOI:10.1186/s13046-021-01894-x

    影响因子 :11.300

    引用产品:164210 164210-50 PB180120 PM150110 PM150210 PM151010

  • The perturbation of parabens on the neuroendocrine system in zebrafish larvae(2023/04/21)

    作者:Jiefeng Liang, Xiaoxi Yang, Tongtong Xiang

    期刊:SCIENCE OF THE TOTAL ENVIRONMENT

    DOI:10.1016/j.scitotenv.2023.163593

    影响因子 :9.800

    引用产品:PM151010 PM151013

  • WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity(2023/01/07)

    作者:Xiaosong Wei, Beibei Wang, Zixin Wu

    期刊:CANCER LETTERS

    DOI:10.1016/j.canlet.2023.216058

    影响因子 :9.700

    引用产品:CL-0002 CL-0125 CL-0222 CL-0227 CL-0449A CL-0463 CL-0628 PM150410 PM150710 PM150910 PM151010

  • Exosomal miR-625-3p secreted by cancer-associated fibroblasts in colorectal cancer promotes EMT and chemotherapeutic resistance by blocking the CELF2/WWOX pathway(2022/11/03)

    作者:Ying Zhang, Changjun Yin, Chao Wei, Shuai Xia, Zhu Qiao, Xue-Wen Zhang, Bin Yu, Jun Zhou, Rong Wang

    期刊:PHARMACOLOGICAL RESEARCH

    DOI:10.1016/j.phrs.2022.106534

    影响因子 :9.300

    引用产品:PM151010

  • CL4-modified exosomes deliver lncRNA DARS-AS1 siRNA to suppress triple-negative breast cancer progression and attenuate doxorubicin resistance by inhibiting autophagy(2023/08/05)

    作者:Xinli Liu, Ge Zhang, Tongyao Yu

    期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

    DOI:10.1016/j.ijbiomac.2023.126147

    影响因子 :8.200

    引用产品:PM150110 PM150210 PM151010

  • PSMD12 interacts with CDKN3 and facilitates pancreatic cancer progression(2023/04/10)

    作者:Jia Ma, Wenyang Zhou, Yifeng Yuan

    期刊:Cancer Gene Therapy

    DOI:10.1038/s41417-023-00609-y

    影响因子 :6.400

    引用产品:CL-0059 PM150510 PM151010

  • Circular RNA circ-ERBB2 Elevates the Warburg Effect and Facilitates Triple-Negative Breast Cancer Growth by the MicroRNA 136-5p/Pyruvate Dehydrogenase Kinase 4 Axis | Molecular and Cellular Biology(2021/9/24)

    作者:Yihong Huang, Shuo Zheng, Ying Lin, Liming Kea

    期刊:Molecular And Cellular Biology

    DOI:10.1128/MCB.00609-20

    影响因子 :5.300

    引用产品:164210 CL-0041 CL-0150A CL-0152A CL-0290A CL-0525 PB180120 PM150110 PM151010

  • GID2 interacts with CDKN3 and regulates pancreatic cancer growth and apoptosis(2023/02/23)

    作者:Xin Deng, Jia Ma, Wenyang Zhou

    期刊:LABORATORY INVESTIGATION

    DOI:10.1016/j.labinv.2023.100122

    影响因子 :5.000

    引用产品:CL-0059 PM150510 PM151010

  • Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin(2021/6/2)

    作者:Yan Wang, Zhiqiang Cheng, Jing Xu

    期刊:Bioengineered

    DOI:10.1080/21655979.2021.1924544

    影响因子 :4.900

    引用产品:CL-0114 CL-0149 CL-0150A PM151010

  • Timosaponin B-II alleviates osteoarthritis-related inflammation and extracellular matrix degradation through inhibition of mitogen-activated protein kinases and nuclear factor-κB pathways in vitro(2022/01/30)

    作者:Xinwei Liu, Dulei Xiang, Wenming Jin

    期刊:Bioengineered

    DOI:10.1080/21655979.2021.2024685

    影响因子 :4.900

    引用产品:PM151010

  • PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1(2021/07/26)

    作者:Yihui Ma, Peiyi Xia, Zhengyang Wang

    期刊:Neoplasia

    DOI:doi.org/10.1016/j.neo.2021.07.004

    影响因子 :4.800

    引用产品:PM150510 PM151010

  • ARHGAP25 suppresses the development of breast cancer by an ARHGAP25/Wnt/ASCL2 feedback loop(2023/06/16)

    作者:Sijia Han, Xueying Jin, Tianyu Hu

    期刊:CARCINOGENESIS

    DOI:10.1093/carcin/bgad042

    影响因子 :4.700

    引用产品:CL-0211 CL-0228 PM150710 PM151010

  • Induction of oocyte maturation and changes in the biochemical composition, physiology and molecular biology of oocytes during maturation and hydration in the orange-spotted grouper (Epinephelus coioides)(2020/2/12)

    作者:Lin Tang, Xinxun Xiao, Herong Shi

    期刊:Aquaculture

    DOI:10.1016/j.aquaculture.2020.735115

    影响因子 :4.500

    引用产品:PM151010

  • Preliminary study on the main mode of the death of red blood cells in grass carp (Ctenopharyngodon idella)(2022/11/24)

    作者:Hong Chen, Minshan Yao, Yin Tang, Lixiang Wei, Junyan Lin, Fei Shi, Fanbin Zhan, Yanan Li, Jun Li, Li Lin, Zhendong Qin

    期刊:Aquaculture

    DOI:10.1016/j.aquaculture.2022.739071

    影响因子 :4.500

    引用产品:PB180352 PM151010

  • MiR-519d and miR-328-3p Combinatorially Suppress Breast Cancer Progression(2020/12/18)

    作者:Haiming Ma, Tao Liu, Yanhua Xu

    期刊:OncoTargets and Therapy

    DOI:10.2147/OTT.S281962

    影响因子 :4.345

    引用产品:164210 PB180120 PB180432 PM150312 PM150410 PM150710 PM151010

  • Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer(2022/08/02)

    作者:Bo Zhang, Wenbin Cao, Yang Liu

    期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY

    DOI:10.1007/s11010-022-04525-x

    影响因子 :4.300

    引用产品:164210 164210-50 CL-0096 CL-0144 PM150710 PM151010

  • Pseudolaric acid B induces apoptosis associated with the mitochondrial and PI3K/AKT/mTOR pathways in triple‑negative breast cancer(2023/09/14)

    作者:Ke Yang, Junqi Wang, Kai Li

    期刊:ONCOLOGY REPORTS

    DOI:10.3892/or.2023.8630

    影响因子 :4.200

    引用产品:164210-50 PM150312 PM151010

  • LAPTM5 regulated by FOXP3 promotes the malignant phenotypes of breast cancer through activating the Wnt/β‑catenin pathway(2023/02/10)

    作者:Sijia Han, Xueying Jin, Tianyu Hu, Feng Chi

    期刊:ONCOLOGY REPORTS

    DOI:10.3892/or.2023.8497

    影响因子 :4.200

    引用产品:CL-0211 CL-0228 PM150710 PM151010

  • CKAP2L, transcriptionally inhibited by FOXP3, promotes breast carcinogenesis through the AKT/mTOR pathway(2022/01/21)

    作者:Feng Chi, Long Chen, Xiaoming Jin

    期刊:EXPERIMENTAL CELL RESEARCH

    DOI:10.1016/j.yexcr.2022.113035

    影响因子 :3.700

    引用产品:CL-0150A CL-0211 CL-0228 CL-0290A PM150710 PM151010

  • hsa_circ_0020378 regulating miR-339-3p/COL1A1 promotes osteosarcoma progression(2023/11/18)

    作者:Liang Liu, Wenze Huang

    期刊:CANCER BIOLOGY & THERAPY

    DOI:10.1080/15384047.2023.2274120

    影响因子 :3.600

    引用产品:PM151010

  • STAM binding protein regulated by hsa_circ_0007334 exerts oncogenic potential in pancreatic cancer(2022/08/30)

    作者:Shan Yu, Changyong E, Jinghui Yang

    期刊:PANCREATOLOGY

    DOI:10.1016/j.pan.2022.08.010

    影响因子 :3.600

    引用产品:CL-0448A PM151010

  • Isoliquiritin modulates ferroptosis via NF-κB signalling inhibition and alleviates doxorubicin resistance in breast cancer(2023/01/05)

    作者:Jiguo Wang, Yang Li, Jing Zhang

    期刊:IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

    DOI:10.1080/08923973.2023.2165943

    影响因子 :3.300

    引用产品:164210 CL-0525 CM-0525 PB180120 PM150410 PM151010

  • Karyopherin Subunit Alpha 1 Enhances the Malignant Behaviors of Colon Cancer Cells via Promoting Nuclear Factor-κB p65 Nuclear Translocation(2023/04/10)

    作者:Lianrong Zhao, Di Wu, Qiao Qu

    期刊:DIGESTIVE DISEASES AND SCIENCES

    DOI:10.1007/s10620-023-07936-y

    影响因子 :3.100

    引用产品:CL-0629A PM151010

  • The New Role of HNF1A-NAS1/miR-214/INHBA Signaling Axis in Colorectal Cancer(2023/11/24)

    作者:Xuan Zhang, Tao Wu, Rujia Qin

    期刊:Frontiers in Bioscience-Landmark

    DOI:10.31083/j.fbl2811301

    影响因子 :3.100

    引用产品:PM151010

  • Transcriptomic Analysis Revealed the Regulatory Mechanisms of Oocyte Maturation and Hydration in Orange-Spotted Grouper (Epinephelus coioides)(2019/05/25)

    作者:Lin Tang, Jiaxing Chen, Zhifeng Ye

    期刊:Marine Biotechnology

    DOI:10.1007/s10126-019-09902-0

    影响因子 :3.000

    引用产品:PM151010

  • Naringin Inhibits Colorectal Carcinogenesis by Inhibiting Viability of Colorectal Cancer Cells(2023/06/21)

    作者:Juanni Zeng, Jinyu Tan, Li Mo

    期刊:Chinese Journal of Integrative Medicine

    DOI:10.1007/s11655-023-3698-9

    影响因子 :2.900

    引用产品:CL-0050 CL-0096 CL-0118 CL-0223A PM150411 PM150710 PM151010

  • Tumor-promoting properties of enolase-phosphatase 1 in breast cancer via activating the NF-κB signaling pathway(2022/11/15)

    作者:Bu, Yuhui, Hao, Jun, He, Jianchao, Li, Xiaolong, Liu, Yinfeng, Ma, Li

    期刊:MOLECULAR BIOLOGY REPORTS

    DOI:10.1007/s11033-022-08066-w

    影响因子 :2.800

    引用产品:PM151010

  • microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16(2021/08/26)

    作者:Wei Li, Zhe Song, Nan Jia

    期刊:In Vitro Cellular & Developmental Biology-Animal

    DOI:10.1007/s11626-021-00603-4

    影响因子 :2.723

    引用产品:CL-0050 CL-0096 CL-0144 PM150710 PM150910 PM151010

  • Circular RNA circHMCU promotes breast tumorigenesis through miR-4458/PGK1 regulatory cascade(2023/03/23)

    作者:Shubian Qiu, Lele Zou, Ruimin Qiu

    期刊:HEREDITAS

    DOI:10.1186/s41065-023-00275-y

    影响因子 :2.700

    引用产品:CL-0005 CL-0149 CL-0150A CL-0525 PM150210 PM150312 PM150411 PM151010

  • Identification and characterization of the inhibitory effect of ART on colorectal cancer cells using Raman spectroscopy(2022/01/10)

    作者:Senmao Chai,Xiaodong Sun,Chuhua Fu

    期刊:Journal of Raman Spectroscopy

    DOI:10.1002/jrs.6292

    影响因子 :2.500

    引用产品:CL-0096 CL-0223A CL-0225A PM150710 PM151010

  • Hsa_circ_0069094 positively regulates the expression of oncogenic ZNF217 by competitively targeting miR-758–3p to promote the development of breast cancer(2022/11/08)

    作者:Huaqing Ou, Jialing Li, Qinhua Lv, Decai Feng

    期刊:Reproductive Biology

    DOI:10.1016/j.repbio.2022.100708

    影响因子 :2.100

    引用产品:CL-0041 CL-0150A CL-0525 PM150110 PM150210 PM151010

  • Inhibition of glycolysis represses the growth and alleviates the endoplasmic reticulum stress of breast cancer cells by regulating TMTC3(2023/04/10)

    作者:Xue Hu, Baoliang Guo, Tong Sun

    期刊:Open Medicine

    DOI:10.1515/med-2023-0635

    影响因子 :2.100

    引用产品:164210 164215 CL-0149 CL-0211 CL-0525 PB180120 PB180424 PM150140 PM150312 PM150710 PM151010

  • GLIS Family Zinc Finger 3 Promotes Triple-Negative Breast Cancer Progression by Inducing Cell Proliferation, Migration and Invasion, and Activating the NF-κB Signaling Pathway(2023/02/01)

    作者:Chenhao Li, Cuizhi Geng

    期刊:BIOLOGICAL & PHARMACEUTICAL BULLETIN

    DOI:10.1248/bpb.b22-00595

    影响因子 :2.000

    引用产品:CL-0290A PM151010

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