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| 名称 | HCT 116 (人结肠癌细胞) (STR鉴定正确) |
| 别称 | HCT-116; HCT.116; HCT_116; HCT116; CoCL2 |
| 种属 | 人 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养方案A（默认） |
生长培养基:
培养条件:
气相：空气，95%；CO2，5%, 温度：37℃
|
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2-3次/周 |
| 背景描述 | HCT 116细胞是由M·Brattain等人于1979年从患结肠癌的男性病人中分离的三株恶性细胞中的一株。HCT 116细胞在半固体琼脂糖培养基中形成克隆；HCT 116细胞在无胸腺裸鼠有致瘤性，形成肿瘤结节。 |
| 年龄（性别） | 男性；成人 |
| 组织来源 | 结直肠癌 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 肠癌细胞 |
| 生物安全等级 | BSL-1 |
| 倍增时间 | ~25-48 hours |
| 致瘤性 | Yes, in nude mice. |
| 基因表达情况 | carcinoembryonic antigen (CEA) 1 ng per 1×10^6 cells per 10 days. |
| 保藏机构 | ATCC; CCL-247 BCRC; 60349 BCRJ; 0288 DSMZ; ACC-581 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 7,10 D2S1338 16 D3S1358 12,18 D5S818 10,11 D7S820 11,12 D8S1179 10,14,15 D13S317 10,12 D16S539 11,13 D18S51 16,17 D19S433 12 D21S11 29,30 FGA 18,23 PentaD 9,13 PentaE 12,13,14 TH01 8,9 TPOX 8,9 vWA 17,22 D6S1043 13,14 D12S391 17,21 D2S441 11,12 -
STR鉴定图
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参考文献
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Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis(2024/01/17)
作者：Can Cheng, Hanhui Yao, Heng Li
期刊：Acta Pharmaceutica Sinica B
DOI：10.1016/j.apsb.2024.01.006
影响因子 ：14.500
引用产品：CL-0096
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An enhanced cascade-based deep forest model for drug combination prediction(2022/03/10)
作者：Weiping Lin, Lianlian Wu, Yixin Zhang
期刊：Briefings In Bioinformatics
影响因子 ：13.994
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Nitroreductase-instructed supramolecular assemblies for microbiome regulation to enhance colorectal cancer treatments(2022/11/09)
作者：Jiali Chen, Pai Zhang, Yan Zhao, Jie Zhao, Xiaobo Wu, Ruijia Zhang, Ruitao Cha, Qingxin Yao, Yuan Gao
期刊：Science Advances
影响因子 ：13.600
引用产品：CL-0071 CL-0096 CL-0101 CL-0118 PM150110 PM150210 PM150710
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Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilities(2022/07/05)
作者：Yuechao Zhao, Tan Zhang, Xuelian Shen
期刊：MOLECULAR THERAPY
DOI：10.1016/j.ymthe.2022.06.017
影响因子 ：12.910
引用产品：CL-0096
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Targeting ATF4-dependent pro-survival autophagy to synergize glutaminolysis inhibition(2021/07/25)
作者：Shuting Han, Liyuan Zhu, Yiran Zhu
期刊：Theranostics
影响因子 ：12.400
引用产品：CL-0096
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Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA(2022/12/15)
作者：Chi Jin, Tuo Wang, Dongsheng Zhang
期刊：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI：10.1186/s13046-022-02551-7
影响因子 ：11.300
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Agrocybe cylindracea fucoglucogalactan induced lysosome-mediated apoptosis of colorectal cancer cell through H3K27ac-regulated cathepsin D(2023/07/17)
作者：Ziwei Wang, Kunying Chen, Ke Zhang
期刊：CARBOHYDRATE POLYMERS
DOI：10.1016/j.carbpol.2023.121208
影响因子 ：11.200
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The miR-145–MMP1 axis is a critical regulator for imiquimod-induced cancer stemness and chemoresistance(2022/03/28)
作者：Shan Zhu, Ning Yang, Chao Niu
期刊：Pharmacological Research
DOI：10.1016/j.phrs.2022.106196
影响因子 ：9.300
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CHIP-mediated ubiquitination of Galectin-1 predicts colorectal cancer prognosis(2020/01/14)
作者：Weimin Wang, Zhen Zhou, Liangliang Xiang
期刊：International Journal of Biological Sciences
影响因子 ：9.200
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The feedback loop of ANKHD1/lncRNA MALAT1/YAP1 strengthens the radioresistance of CRC by activating YAP1/AKT signaling(2022/02/02)
作者：Pingan Yao, Yong Wu , Kui Zhao
期刊：Cell Death & Disease
DOI：10.1038/s41419-022-04554-w
影响因子 ：9.000
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Detection of circulating tumor cells using antibody-functionalized microchips to monitor tumorigenesis in a mouse model of metastatic breast cancer(2022/12/29)
作者：Qiuyue Wu, Lin Zhu, Xinyu Wei
期刊：SENSORS AND ACTUATORS B-CHEMICAL
影响因子 ：8.400
引用产品：CL-0096
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Anti-colon cancer effects of Spirulina polysaccharide and its mechanism based on 3D models(2022/12/26)
作者：Yingfang Lu, Zexin Chen, Qianmin Lin
期刊：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI：10.1016/j.ijbiomac.2022.12.244
影响因子 ：8.200
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Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis(2020/05/02)
作者：Le Yu, Ling Dong, Hui Li
期刊：Oncogene
影响因子 ：8.000
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PD-1-siRNA Delivered by Attenuated Salmonella Enhances the Antitumor Effect of Chloroquine in Colon Cancer(2021/07/06)
作者：Shuya Lu, Jianhui Gao, Huijie Jia
期刊：Frontiers in Immunology
影响因子 ：7.300
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Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D(2024/01/10)
作者：Chuan Zhou, Zisheng Fan, Yuejiao Gu
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c01622
影响因子 ：7.300
引用产品：CL-0096
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Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5′-UTR RNA G-Quadruplexes(2024/01/25)
作者：Maolin Li, Letian Dai, Zhuoyu Gao
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c01773
影响因子 ：7.300
引用产品：CL-0096
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Design, Synthesis, and Biological Evaluation of Proteolysis-Targeting Chimeras as Highly Selective and Efficient Degraders of Extracellular Signal-Regulated Kinase 5(2023/09/26)
作者：Pengming Pan, Tongtong Geng, Zhongtang Li
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c00864
影响因子 ：7.300
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Mechanism of Bazhen decoction in the treatment of colorectal cancer based on network pharmacology, molecular docking, and experimental validation(2023/09/20)
作者：Shuai Lu, Xibo Sun, Zhongbao Zhou
期刊：Frontiers in Immunology
DOI：10.3389/fimmu.2023.1235575
影响因子 ：7.300
引用产品：CL-0096
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Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers(2023/03/10)
作者：Zehui Zhou, Guizhen Zhou, Chuan Zhou
期刊：JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1021/acs.jmedchem.3c00075
影响因子 ：7.300
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Chlorophyllin Inhibits Mammalian Thioredoxin Reductase 1 and Triggers Cancer Cell Death(2021/10/29)
作者：Shibo Sun, Yici Zhang, Weiping Xu
期刊：Antioxidants
影响因子 ：7.000
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Chronic exposure to low-dose deltamethrin can lead to colon tissue injury through PRDX1 inactivation-induced mitochondrial oxidative stress injury and gut microbial dysbiosis(2023/09/13)
作者：Rulan Ma, Tuanhe Sun, Xueni Wang
期刊：ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
DOI：10.1016/j.ecoenv.2023.115475
影响因子 ：6.800
引用产品：CL-0096
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Design, synthesis and evaluation of N3-substituted quinazolinone derivatives as potential Blooms Syndrome protein (BLM) helicase inhibitor for sensitization treatment of colorectal cancer(2022/11/21)
作者：Jia-Li Tu, Bi-Han Wu, Heng-Bo Wu, Jia-En Wang, Zi-Lin Zhang, Kun-Yu Gao, Lu-Xuan Zhang, Qin-Rui Chen, Ying-Chen Zhou, Jia-Heng Tan, Zhi-Shu Huang, Shuo-Bin Chen
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2022.114944
影响因子 ：6.700
引用产品：CL-0096
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Design, synthesis, and biological evaluation of 1,6-naphthyridine-2-one derivatives as novel FGFR4 inhibitors for the treatment of colorectal cancer(2023/08/04)
作者：Bo Fang, Yinshuang Lai, Hao Yan
期刊：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI：10.1016/j.ejmech.2023.115703
影响因子 ：6.700
引用产品：CL-0096
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METTL3-mediated RanGAP1 promotes colorectal cancer progression through the MAPK pathway by recruiting YTHDF1(2024/01/24)
作者：Rui Yang, Cheng Yang, Danjie Su
期刊：CANCER GENE THERAPY
DOI：10.1038/s41417-024-00731-5
影响因子 ：6.400
引用产品：CL-0096
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Impact of Sulfur Fumigation on Ginger: Chemical and Biological Evidence(2022/09/21)
作者：Weihao Zhang, Hanyan Luo, Jing Fang
期刊：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子 ：6.100
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USP7-mediated JUND suppresses RCAN2 transcription and elevates NFATC1 to enhance stem cell property in colorectal cancer(2023/08/03)
作者：Yunli Chang, Lingling Chen, Jie Tang
期刊：CELL BIOLOGY AND TOXICOLOGY
DOI：10.1007/s10565-023-09822-9
影响因子 ：6.100
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Promotion of intestinal epithelial cell apoptosis by enterotoxigenic Escherichia coli via PKA-mediated inhibition of mTORC1 activation(2023/01/12)
作者：Yining Zheng, Guoyan Wang, Rongnuo Li
期刊：MICROBES AND INFECTION
DOI：10.1016/j.micinf.2023.105099
影响因子 ：5.800
引用产品：CL-0096
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Silencing UNC5B antisense lncRNA 1 represses growth and metastasis of human Colon cancer cells via raising miR-622(2019/12/18)
作者：Yan Zhang, Zhen Li, Zhi Lan
期刊：Artificial Cells Nanomedicine and Biotechnology
DOI：10.1080/21691401.2019.1699809
影响因子 ：5.800
引用产品：CL-0096
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A 3-circular RNA signature as a noninvasive biomarker for diagnosis of colorectal cancer(2019/11/04)
作者：Daoxiong Ye, Sisi Wang, Ying Huang
期刊：Cancer Cell International
影响因子 ：5.800
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Identification and validation of a novel prognosis model based on m5C-related long non-coding RNAs in colorectal cancer(2023/09/05)
作者：Ziyang Di, Gaoran Xu, Zheyu Ding
期刊：Cancer Cell International
DOI：10.1186/s12935-023-03025-2
影响因子 ：5.800
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USP29 activation mediated by FUBP1 promotes AURKB stability and oncogenic functions in gastric cancer(2024/01/17)
作者：Rongfu Tu, Ye Kang, Yiwen Pan
期刊：Cancer Cell International
DOI：10.1186/s12935-024-03224-5
影响因子 ：5.800
引用产品：CL-0096
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Itraconazole inhibits tumor growth via CEBPB-mediated glycolysis in colorectal cancer(2024/01/26)
作者：Yong Zhang, Lu Li, Feifei Chu
期刊：CANCER SCIENCE
影响因子 ：5.700
引用产品：CL-0096
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Autophagy Induction by Trichodermic Acid Attenuates Endoplasmic Reticulum Stress-Mediated Apoptosis in Colon Cancer Cells(2021/5/25)
作者：Junyan Qu, Cheng Zeng, Tingting Zou
期刊：International Journal Of Molecular Sciences
影响因子 ：5.600
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An anti-PD-1 antisense oligonucleotide promotes the expression of soluble PD-1 by blocking the interaction between SRSF3 and an exonic splicing enhancer of PD-1 exon 3(2023/12/04)
作者：Xu Wang, Lingyan Yan, Jihua Guo
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.111280
影响因子 ：5.600
引用产品：CL-0096
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Attenuated Salmonella-delivered PD-1 siRNA enhances the antitumor effects of EZH2 inhibitors in colorectal cancer(2023/09/12)
作者：Mengmeng Lv, Sheng Guo, Xinyu Zhang
期刊：INTERNATIONAL IMMUNOPHARMACOLOGY
DOI：10.1016/j.intimp.2023.110918
影响因子 ：5.600
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Circ_0011385 knockdown inhibits cell proliferation, migration and invasion, whereas promotes cell apoptosis by regulating miR-330-3p/MYO6 axis in colorectal cancer(2022/01/26)
作者：Jing Wang, Shaobo Ke, Yi Gong
期刊：Biomedical Journal
影响因子 ：5.500
引用产品：164210 164210-50 CL-0096 CL-0144 CL-0223 CL-0225 PM150110 PM150210
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Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells(2023/03/12)
作者：Hao Kuang, Xuehua Sun, Ying Liu
期刊：FEBS Journal
影响因子 ：5.400
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Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer(2020/01/03)
作者：Man Hu, Zhaomin Yu, Peiyuan Mei
期刊：Aging-US
影响因子 ：5.200
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Characterization of SHCBP1 to prognosis and immunological landscape in pan-cancer: novel insights to biomarker and therapeutic targets(2023/03/14)
作者：Fei Jiang, Yanlong Shi, Yue Wang
期刊：Aging-US
影响因子 ：5.200
引用产品：CL-0096
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Structures and antitumor activities of ten new and twenty known surfactins from the deep-sea bacterium Limimaricola sp. SCSIO 53532( 2021/12/31)
作者：Wenping Ding, Yanqun Li, Min Chen
期刊： BIOORGANIC CHEMISTRY
DOI：10.1016/j.bioorg.2021.105589
影响因子 ：5.100
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Berberine promotes IGF2BP3 ubiquitination by TRIM21 to induce G1/S phase arrest in colorectal cancer cells(2023/02/21)
作者：Zhenwei Gui, Jingwei Li, Juan Li
期刊：CHEMICO-BIOLOGICAL INTERACTIONS
影响因子 ：5.100
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Exosomal circCOL1A2 from cancer cells accelerates colorectal cancer progression via regulating miR-665/LASP1 signal axis(2023/04/12)
作者：Zhi Miao, Xiaomeng Zhao, Xiang Liu
期刊：EUROPEAN JOURNAL OF PHARMACOLOGY
DOI：10.1016/j.ejphar.2023.175722
影响因子 ：5.000
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MicroRNA-934 facilitates cell proliferation, migration, invasion and angiogenesis in colorectal cancer by targeting B-cell translocation gene 2(2021/10/16)
作者：Bo Li, Xianyi Liu, Guogang Wu
期刊：Bioengineered
DOI：10.1080/21655979.2021.1996505.
影响因子 ：4.900
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Long noncoding RNA SNHG10 promotes colorectal cancer cells malignant progression by targeting miR-3690(2021/9/3)
作者：Hao Zhang, Zhenghua Fang, Yesong Guo
期刊：Bioengineered
DOI：10.1080/21655979.2021.1972199
影响因子 ：4.900
引用产品：CL-0096
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Notum palmitoleoyl-protein carboxylesterase regulates Fas cell surface death receptor-mediated apoptosis via the Wnt signaling pathway in colon adenocarcinoma(2021/8/17)
作者：Hua Gong, Qiang Niu, Yi Zhou
期刊：Bioengineered
DOI：10.1080/21655979.2021.1961657
影响因子 ：4.900
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Blocking NFATc3 ameliorates azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer in mice via the inhibition of inflammatory responses and epithelial-mesenchymal transition(2020/07/10)
作者：Yan Lin, Moussa Harouna Koumba, Suxuan Qu
期刊：Cellular Signalling
DOI：10.1016/j.cellsig.2020.109707
影响因子 ：4.800
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miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition(2020/3/13)
作者：Lianjie Lin, Dongxu Wang, Suxuan Qu
期刊：Drug Design Development and Therapy
影响因子 ：4.800
引用产品：CL-0096
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Integrated analysis of single cell and bulk RNA sequencing identifies CTHRC1+INHBA+CAF as drivers of colorectal cancer progression(2023/08/04)
作者：Shangshang Hu, Jian Qin, Rui Gao
期刊：MOLECULAR CARCINOGENESIS
DOI：10.1002/mc.23615
影响因子 ：4.600
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Colorectal cancer with low SLC35A3 is associated with immune infiltrates and poor prognosis(2024/01/03)
作者：Shuai Lu, Xibo Sun, Huazhen Tang
期刊：Scientific Reports
DOI：10.1038/s41598-023-51028-w
影响因子 ：4.600
引用产品：CL-0096
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Inhibition of MORC2 Mediates HDAC4 to Promote Cellular Senescence through p53/p21 Signaling Axis(2022/09/22)
作者：Kepeng Ou, Youjian Li, Yiling Long
期刊：MOLECULES
影响因子 ：4.600
引用产品：CL-0096
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Variation of Saponins in Sanguisorba officinalis L. before and after Processing (Paozhi) and Its Effects on Colon Cancer Cells In Vitro(2022/12/19)
作者：Zhengyang Wang, Chunjuan Yang, Lihong Wu
期刊：MOLECULES
影响因子 ：4.600
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Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway(2023/12/27)
作者：Fenglin Luo, Yimeng Tang, Lin Zheng
期刊：Pharmaceuticals
影响因子 ：4.600
引用产品：CL-0096
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Up-Regulation of SH3TC2 Induced by YTHDF1 Predicts Poor Outcome and Facilitates Cell-Cycle Progress in Colorectal Cancer(2022/12/15)
作者：Huili Wu, Feifei Chu, Lu Li
期刊：Journal of Oncology
影响因子 ：4.501
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Identification of KIF21B as a Biomarker for Colorectal Cancer and Associated with Poor Prognosis(2022/11/21)
作者：Shanshan Xu, Youran Li, Hua Huang, Xian Miao, Yunfei Gu
期刊：Journal of Oncology
影响因子 ：4.501
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Matrine restrains the development of colorectal cancer through regulating the AGRN/Wnt/β-catenin pathway(2023/01/09)
作者：Xianzhe Li, Ye Lu, Penghao Wen
期刊：ENVIRONMENTAL TOXICOLOGY
影响因子 ：4.500
引用产品：CL-0096
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CD155/TIGIT signaling regulates the effector function of tumor-infiltrating CD8+ T cell by NF-κB pathway in colorectal cancer(2021/11/12)
作者：Shanshan Li, Jihu Ding, Ying Wang
期刊：Journal Of Gastroenterology And Hepatology
影响因子 ：4.369
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Annexin A9 promotes cell proliferation by regulating the Wnt signaling pathway in colorectal cancer(2023/06/22)
作者：Xuemei Lu, Liqiang Hu, Jiayan Mao
期刊：Human Cell
DOI：10.1007/s13577-023-00939-x
影响因子 ：4.300
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Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer(2022/08/02)
作者：Bo Zhang, Wenbin Cao, Yang Liu
期刊：MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI：10.1007/s11010-022-04525-x
影响因子 ：4.300
引用产品：164210 164210-50 CL-0096 CL-0144 CL-0223 CL-0225 PM150710 PM151010
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Deoxycholic acid-modified microporous SiO2 nanofibers mimicking colorectal microenvironment to optimize radiotherapy-chemotherapy combined therapy(2021/10/12)
作者：Lihuan Wang, Congzhao Zhao, Haoru Shan
期刊：Biomedical Materials
影响因子 ：4.103
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Site-directed Late-Stage Diversification of Macrocyclic Nannocystins Facilitating Anticancer SAR and Mode of Action Studies(2022/12/22)
作者：Han Zhang, Yunfeng Tian, Xiaoya Yuan
期刊：RSC Medicinal Chemistry
影响因子 ：4.100
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CILP2: A prognostic biomarker associated with immune infiltration in colorectal cancer.(2023/04/20)
作者：Xueli Wang, Yu Zhang, Niping Song
期刊：Heliyon
DOI：10.1016/j.heliyon.2023.e15535
影响因子 ：4.000
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miR-140-3p inhibits colorectal cancer progression and its liver metastasis by targeting BCL9 and BCL2(2021/04/10)
作者：Dingsheng Liu, Chunsheng Chen, Mingming Cui
期刊：Cancer Medicine
影响因子 ：4.000
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5-Aza-2′-deoxycytidine advances the epithelial–mesenchymal transition of breast cancer cells by demethylating Sipa1 promoter-proximal elements(2020/05/11)
作者：Ang Lu, Wei Wang, Shu Fang
期刊：Journal of Cell Science
影响因子 ：4.000
引用产品：CL-0096
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Targeting proteasome enhances anticancer activity of oncolytic HSV-1 in colorectal cancer(2022/11/11)
作者：Xiaxi Li, Wei Hu, Jiangang Shen, Mingsong Li, Wei Gong
期刊：VIROLOGY
DOI：10.1016/j.virol.2022.11.002
影响因子 ：3.700
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Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway(2023/06/22)
作者：Weiwei Zheng, Yingchang Guo, Guangtan Zhang
期刊：PLoS One
DOI：10.1371/journal.pone.0287133
影响因子 ：3.700
引用产品：CL-0096
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P300 increases CSNK2A1 expression which accelerates colorectal cancer progression through activation of the PI3K-AKT-mTOR axis(2023/06/28)
作者：Jilong Liu
期刊：EXPERIMENTAL CELL RESEARCH
DOI：10.1016/j.yexcr.2023.113694
影响因子 ：3.700
-
A bicyclic pentapeptide-based highly potent and selective pan-SIRT1/2/3 inhibitor harboring Nε-thioacetyl-lysine(2020/4/1)
作者：Renwu Li, Lingling Yan, Xun Sun
期刊：BIOORGANIC & MEDICINAL CHEMISTRY
DOI：10.1016/j.bmc.2020.115356.
影响因子 ：3.500
引用产品：CL-0096
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The bromodomain and extra-terminal domain inhibitor JQ1 synergistically sensitizes human colorectal cancer cells to topoisomerase I inhibitors through repression of Mre11-mediated DNA repair pathway(2020/09/26)
作者：Linping Lei, Xuqin Xie, Long He
期刊：Investigational New Drugs
DOI：10.1007/s10637-020-01014-0
影响因子 ：3.400
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Vitamin C inhibits the growth of colorectal cancer cell HCT116 and reverses the glucose-induced oncogenic effect by downregulating the Warburg effect(2023/09/13)
作者：Chang Yu, Su Min, Feng Lv
期刊：MEDICAL ONCOLOGY
DOI：10.1007/s12032-023-02155-x
影响因子 ：3.400
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CircCSNK1G1 Contributes to the Development of Colorectal Cancer by Increasing the Expression of MYO6 via Competitively Targeting miR-455-3p(2020/10/2)
作者：Xianming Huang, Xiaohua Shen, Lixiang Peng
期刊：Cancer Management and Research
影响因子 ：3.300
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Sevoflurane inhibits malignant progression of colorectal cancer via hsa_circ_0000231-mediated miR-622(2021/6/28)
作者：Jingpeng Wang, Shuyuan Li, Gaofeng Zhang
期刊：Journal of Biological Research-Thessaloniki
DOI：10.1186/s40709-021-00145-6
影响因子 ：3.300
-
Circ_0029803 serves as the sponge of miR-216b-5p to promote the progression of colorectal cancer by regulating SKIL expression(2021/09/03)
作者：Linfei Huang , Lei Zhu , Sheng Pan
期刊：World Journal of Surgical Oncology
DOI：10.1186/s12957-021-02368-2
影响因子 ：3.200
-
Maintenance of the Expression of c-FLIPL by Hsp70 to Resist Licochalcone A-Induced Anti-Colorectal Cancer Effect through ERK-Mediated Autophagy Induction(2023/12/01)
作者：Tianpeng Li, Ting Li, Hongbin Zhang
期刊：Frontiers in Bioscience-Landmark
影响因子 ：3.100
引用产品：CL-0096
-
PEX26 Functions as a Metastasis Suppressor in Colorectal Cancer(2023/11/13)
作者：Bianbian Yan, Lichao Cao, Liyang Gao
期刊：DIGESTIVE DISEASES AND SCIENCES
DOI：10.1007/s10620-023-08168-w
影响因子 ：3.100
引用产品：CL-0096
-
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway(2022/08/15)
作者：Xiaolong Zhang, Lifei Tian, Zeyu Li
期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI：10.1016/j.bbrc.2022.08.036
影响因子 ：3.100
-
Astragaloside IV regulates circ_0001615 and miR-873-5p/LASP1 axis to suppress colorectal cancer cell progression(2024/01/04)
作者：Pengfei Kong, Xuemei Tang, Fang Liu
期刊：Chemical Biology & Drug Design
影响因子 ：3.000
引用产品：CL-0096
-
MicroRNA‑9‑5p increases the sensitivity of colorectal cancer cells to 5‑fluorouracil by downregulating high mobility group A2 expression(2021/1/26)
作者：Huizhe Zheng, Bin Yan, Qi Wu
期刊：Oncology Letters
影响因子 ：2.900
引用产品：CL-0096
-
microRNA-4429-5p suppresses the malignant development of colon cancer by targeting matrix metalloproteinase 16(2021/08/26)
作者：Wei Li, Zhe Song, Nan Jia
期刊：In Vitro Cellular & Developmental Biology-Animal
DOI：10.1007/s11626-021-00603-4
影响因子 ：2.723
引用产品：CL-0050 CL-0096 CL-0144 CL-0223 CL-0225 PM150710 PM150910 PM151010
-
Calorie restriction remodels gut microbiota and suppresses tumorigenesis of colorectal cancer in mice(2022/12/08)
作者：Xingchen Dai, Yuhuan Zhang, Yongli Huang
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.700
引用产品：CL-0096
-
circASS1 overexpression inhibits the proliferation, invasion and migration of colorectal cancer cells by regulating the miR‑1269a/VASH1 axis(2021/8/10)
作者：HaiLin Xiong, XiaoHua Zhong, XiaoHong Guo
期刊：Experimental and Therapeutic Medicine
影响因子 ：2.700
-
Identifying Active Compounds and Mechanism of Camellia nitidissima Chi on Anti-Colon Cancer by Network Pharmacology and Experimental Validation(2021/08/26)
作者：Yiwei Chen, Erwei Hao, Fan Zhang
期刊：Evidence-Based Complementary and Alternative Medicine
影响因子 ：2.650
引用产品：CL-0096
-
Circular RNA (circ)_0053277 Contributes to Colorectal Cancer Cell Growth, Angiogenesis, Metastasis and Glycolysis(2023/11/02)
作者：Jianbin Zhuang, Weiliang Song, Minghao Li
期刊：MOLECULAR BIOTECHNOLOGY
DOI：10.1007/s12033-023-00936-3
影响因子 ：2.600
引用产品：CL-0096
-
Identification and characterization of the inhibitory effect of ART on colorectal cancer cells using Raman spectroscopy(2022/01/10)
作者：Senmao Chai,Xiaodong Sun,Chuhua Fu
期刊：Journal of Raman Spectroscopy
DOI：10.1002/jrs.6292
影响因子 ：2.500
-
Circ_0005785 Silencing Constrains the Functional Properties of Colorectal Cancer Cells Depending on miR-7-5p/DNMT3A Axis(2023/09/20)
作者：Zhu Li, Gangling Tong, Xiaodan Peng
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-023-10522-6
影响因子 ：2.400
-
High Expression of circ_0001821 Promoted Colorectal Cancer Progression Through miR-600/ISOC1 Axis(2022/08/09)
作者：Cheng Li, Xudong Gao, Yi Zhao
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-022-10262-z
影响因子 ：2.400
引用产品：CL-0096
-
Circ_0000370 Plays an Oncogenic Role in Colorectal Cancer by Regulating the miR-502-5p/SIRT1 Axis(2023/08/10)
作者：Zhu Li, Gangling Tong, Xiaodan Peng
期刊：BIOCHEMICAL GENETICS
DOI：10.1007/s10528-023-10468-9
影响因子 ：2.400
-
Circ_0000467 Exerts an Oncogenic Role in Colorectal Cancer via miR-330-5p-Dependent Regulation of TYRO3(2022/01/18)
作者：Yubao Huang, Zhiyu Chen, Xiong Zhou, Hai Huang
期刊：Biochemical Genetics
DOI：10.1007/s10528-021-10171-7
影响因子 ：2.400
-
Circ_0007031 Silencing Inhibits Cell Proliferation and Induces Cell Apoptosis via Downregulating MELK at a miR-485-3p-Dependent Way in Colorectal Cancer(2021/7/28)
作者：Shengtian Su, Wenjing Lu, Jun Liu
期刊：Biochemical Genetics
DOI：10.1007/s10528-021-10111-5
影响因子 ：2.400
-
Circ_KIAA1199 inhibits MSI1 degradation by targeting miR-34c-5p to drive the malignant cell behaviors and tumor growth of colorectal cancer(2022/01/01)
作者：Yanbo Zhang, Hailong Yu, Zhen Guo
期刊：Anti-Cancer Drugs
DOI：10.1097/CAD.0000000000001164
影响因子 ：2.300
-
Atractylenolide III induces apoptosis by regulating the Bax/Bcl-2 signaling pathway in human colorectal cancer HCT-116 Cells in vitro and in vivo(2022/01/01)
作者：Dan Zhang, Xiaofang Li, Daqiang Song
期刊：Anti-Cancer Drugs
DOI：10.1097/CAD.0000000000001136
影响因子 ：2.300
-
A new anthraquinone derivative from the marine fish-derived fungus Alternaria sp. X112(2023/09/13)
作者：Xiaoyuan Xu, Gang Li, Rao Fu
期刊：NATURAL PRODUCT RESEARCH
DOI：10.1080/14786419.2023.2258540
影响因子 ：2.200
-
Protein Kinase D1 Correlates with Less Lymph Node Metastasis Risk, Enhanced 5-FU Sensitivity, and Better Prognosis in Colorectal Cancer(2023/08/11)
作者：Bo Huang, Zhuo He
期刊：TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
影响因子 ：2.200
-
TRIM29 knockdown prevented the colon cancer progression through decreasing the ubiquitination levels of KRT5(2023/08/30)
作者：Lihui Sun, Dawei Wang, Zhenyu Chen
期刊：Open Life Sciences
影响因子 ：2.200
-
NCAPG is transcriptionally regulated by CBX3 and activates the Wnt/β-catenin signaling pathway to promote proliferation and the cell cycle and inhibit apoptosis in colorectal cancer(2023/02/27)
作者：Hong Yang, Leilei Pu, Ruobing Li
期刊：Journal of Gastrointestinal Oncology
影响因子 ：2.100
-
MicroRNA miR-425 inhibits proliferation and migration of colorectal cancer HCT116 cells(2021/9/1)
作者：Huifang Zhou, Wen Liu, Haiyun Chen
期刊：Journal Of The Pakistan Medical Association
影响因子 ：0.900
引用产品：CL-0096
-
miRNA-101通过靶向CDK8调控结肠癌细胞侵袭和Wnt/β-catenin通路活化(2018/05/18)
作者：龙建辰, 赵泉, 杜晓倩
期刊：肿瘤防治研究
DOI：10.3971/j.issn.1000-8578.2018.17.1558
影响因子 ：0.702
-
The Upregulation of GSTO2 is Associated with Colon Cancer Progression and a Poor Prognosis(2023/01/11)
作者：Xingyu Peng, Jinfeng Zhu, Sicheng Liu
期刊：Journal of Oncology
影响因子 ：0.000
-
Investigation of the Effects of Glabridin on the Proliferation, Apoptosis, and Migration of the Human Colon Cancer Cell Lines SW480 and SW620 and Its Mechanism Based on Reverse Virtual Screening and Proteomics(2023/01/05)
作者：Tingting Li, Hang Li, Wenxin Xia
期刊：Oxidative Medicine and Cellular Longevity
影响因子 ：0.000
