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产品概述
名称 | MKN-45 (人胃癌细胞)(STR鉴定正确) |
种属 | 人 |
生长特性 | 半贴半悬 |
细胞形态 | 圆形 |
生长培养基 | RPMI-1640+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | MKN-45 细胞是由 Hojo H建立,源于日本一位62岁低分化胃腺癌女性患者的肝转移灶。 |
年龄(性别) | 女;62岁 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胃癌细胞 |
生物安全等级 | 1 |
倍增时间 | ~30-60 hours |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 12 D2S1338 18 D3S1358 15,16 D5S818 10,11 D7S820 10,11 D8S1179 13,17 D13S317 8,11 D16S539 10 D18S51 16 D19S433 14,16.2 D21S11 31 FGA 19,24 PentaD 10 PentaE 10 TH01 7 TPOX 8 vWA 19 D6S1043 14 D12S391 26 D2S441 11 -
STR鉴定图
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参考文献
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Neutrophil extracellular traps promote angiogenesis in gastric cancer(2023/07/21)
作者:Shifeng Yang, Boshi Sun, Jiacheng Li
期刊:Cell Communication and Signaling
DOI:10.1186/s12964-023-01196-z
影响因子 :8.400
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CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1(2022/11/12)
作者:Li, Dongbao, Wang, Yuhong, Dong, Chao, Chen, Tao, Dong, Anqi, Ren, Jiayu, Li, Weikang, Shu, Gege, Yang, Jiaoyang, Shen, Wenhao, Qin, Lei, Hu, Lin, Zhou, Jin
期刊:ONCOGENE
DOI:10.1038/s41388-022-02537-x
影响因子 :8.000
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Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis(2023/01/05)
作者:Chenggang Zhang, Guanxin Wei, Xiuxian Zhu
期刊:International Journal of Nanomedicine
影响因子 :8.000
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Compound Kushen Injection inhibits epithelial-mesenchymal transition of gastric carcinoma by regulating VCAM1 induced by the TNF signaling pathway(2023/07/17)
作者:Zhihong Huang, Chao Wu, Wei Zhou
期刊:PHYTOMEDICINE
DOI:10.1016/j.phymed.2023.154984
影响因子 :7.900
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The regulatory role of cancer stem cell marker gene CXCR4 in the growth and metastasis of gastric cancer(2023/09/07)
作者:Hongying Zhao, Rongke Jiang, Chunmei Zhang
期刊:npj Precision Oncology
DOI:10.1038/s41698-023-00436-2
影响因子 :7.900
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Computed tomography-detected extramural venous invasion-related gene signature: a potential negative biomarker of immune checkpoint inhibitor treatment in patients with gastric cancer(2023/01/05)
作者:Hao Yang, Xinyi Gou, Caizhen Feng
期刊:Journal of Translational Medicine
DOI:10.1186/s12967-022-03845-2
影响因子 :7.400
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Identification of lactylation related model to predict prognostic, tumor infiltrating immunocytes and response of immunotherapy in gastric cancer(2023/03/03)
作者:Hao Yang, Xiaoming Zou, Shifeng Yang
期刊:Frontiers in Immunology
DOI:10.3389/fimmu.2023.1149989
影响因子 :7.300
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LINC01354 enhances the metastatic ability of gastric cancer cells by adjusting miR-153-5p/CADM2 expression(2023/06/15)
作者:Fa Fang, Yin Gu, Jie Gao
期刊:American Journal of Cancer Research
DOI:PMID:37424819
影响因子 :5.300
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Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec498 Residue of Cytosolic Selenoprotein Thioredoxin Reductase(2023/09/28)
作者:Minghui Liu, Shibo Sun, Yao Meng
期刊:MOLECULES
影响因子 :4.600
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Depletion of hsa_circ_0000144 Suppresses Oxaliplatin Resistance of Gastric Cancer Cells by Regulating miR-502-5p/ADAM9 Axis(2021/04/20)
作者:Haifeng Gao, Jiajia Xu, Fen Qiao
期刊:OncoTargets and Therapy
影响因子 :4.345
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Macrophage-derived exosomes regulate gastric cancer cell oxaliplatin resistance by wrapping circ 0008253(2022/11/23)
作者:Dandan Yu, Zhiwei Chang, Xiaolei Liu, Pengfei Chen, Huixian Zhang, Yanru Qin
期刊:CELL CYCLE
DOI:10.1080/15384101.2022.2146839
影响因子 :4.300
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LncRNA SNHG6 knockdown inhibits cisplatin resistance and progression of gastric cancer through miR-1297/BCL-2 axis(2021/12/22)
作者:Jiazhan Mei, Guiju Liu, Ruijun Li
期刊:Bioscience Reports
影响因子 :4.000
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TYMSOS drives the proliferation, migration, and invasion of gastric cancer cells by regulating ZNF703 via sponging miR-4739(2021/4/12)
作者:Yulan Gu, Chuandan Wan, Guoqiang Zhou
期刊:Cell Biology International
影响因子 :3.900
引用产品:CL-0292
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Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway(2022/03/02)
作者:Dong Tan, Yafei Zhang
期刊:Toxicology And Applied Pharmacology
DOI:10.1016/j.taap.2022.115968
影响因子 :3.800
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LINC_00355 promotes gastric cancer progression by upregulating PHF19 expression through sponging miR-15a-5p(2021/06/02)
作者:Jishui Zhang, Wenhao Lv, Yagang Liu
期刊:Bmc Cancer
DOI:10.1186/s12885-021-08227-3
影响因子 :3.800
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Long non‑coding RNA lnc‑GNAT1‑1 inhibits gastric cancer cell proliferation and invasion through the Wnt/β‑catenin pathway in Helicobacter pylori infection(2018/8/20)
作者:Liping Liu, Tiankui Shuai, Bin Li
期刊:Molecular Medicine Reports
影响因子 :3.400
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Long Noncoding RNA SNHG22 Induces Cell Migration, Invasion, and Angiogenesis of Gastric Cancer Cells via microRNA-361-3p/HMGA1/Wnt/β-Catenin Axis(2020/12/15)
作者:Xiaofeng Cui, Huaiyu Zhang, Tong Chen
期刊:Cancer Management and Research
影响因子 :3.300
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Circ_0032821 Facilitates Gastric Cancer Cell Proliferation, Migration, Invasion and Glycolysis by Regulating MiR-1236-3p/HMGB1 Axis(2020/10/12)
作者:Lei Chen, Kun Chi, Huaguo Xiang
期刊:Cancer Management and Research
影响因子 :3.300
引用产品:164210 164210-50 CL-0022 CL-0107 CL-0169 CL-0292 CL-0563 PB180120 PM150110
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CREB1 Suppresses Transcription of microRNA-186 to Promote Growth, Invasion and Epithelial–Mesenchymal Transition of Gastric Cancer Cells Through the KRT8/HIF-1α Axis(2020/9/25)
作者:Xue Huang, Fujian Liu, Zhiyong Jiang
期刊:Cancer Management and Research
影响因子 :3.300
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Achaete-scute complex-like 2 regulated inflammatory mechanism through Toll-like receptor 4 activating in stomach adenocarcinoma(2022/08/25)
作者:Enqi Zheng, Zhun Cai, Wangyong Li
期刊:World Journal of Surgical Oncology
DOI:10.1186/s12957-022-02722-y
影响因子 :3.200
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The GLI2/CDH6 axis enhances migration, invasion and mitochondrial fission of stomach adenocarcinoma cells(2023/07/24)
作者:Guangyi Liu, Huan Wang, Rui Ran
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.07.038
影响因子 :3.100
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Flavonoid-Rich Extract of Oldenlandia diffusa (Willd.) Roxb. Inhibits Gastric Cancer by Activation of Caspase-Dependent Mitochondrial Apoptosis(2022/08/31)
作者:Jiayin Ling, Qiulan Wang, Haonan Liang
期刊:Chinese Journal of Integrative Medicine
影响因子 :2.900
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SPI1 Mediates N-Myristoyltransferase 1 to Advance Gastric Cancer Progression via PI3K/AKT/mTOR Pathway(2023/03/17)
作者:Ping Qiu, Xing Li, Min Gong
期刊:Canadian Journal of Gastroenterology and Hepatology
影响因子 :2.700
引用产品:164210 CL-0001 CL-0022 CL-0107 CL-0292 CL-0563 PB180120 PM150110 PM150467 PM150510 PM150810
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Ubiquitin-specific protease 1 overexpression indicates poor prognosis and promotes proliferation, migration, and invasion of gastric cancer cells(2021/12/29)
作者:Debin Meng, Delong Li
期刊:Tissue & Cell
DOI:10.1016/j.tice.2021.101723
影响因子 :2.600
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Isoquercitrin Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Gastric Cancer Cells(2022/12/08)
作者:Jiang Liu, LiJun Ren, HaoWen Wang
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10309-1
影响因子 :2.400
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A new anthraquinone derivative from the marine fish-derived fungus Alternaria sp. X112(2023/09/13)
作者:Xiaoyuan Xu, Gang Li, Rao Fu
期刊:NATURAL PRODUCT RESEARCH
DOI:10.1080/14786419.2023.2258540
影响因子 :2.200
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Curcumin suppresses the progression of gastric cancer by regulating circ_0056618/miR-194-5p axis(2021/1/1)
作者:Shan Li, Lihai Zhang, Shuhua Li
期刊:Open Life Sciences
影响因子 :2.200
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RNA-binding protein ENO1 promotes the tumor progression of gastric cancer by binding to and regulating gastric cancer-related genes(2023/04/17)
作者:Na Wang, Hui Qiao, Jianpeng Hao
期刊:Journal of Gastrointestinal Oncology
影响因子 :2.100
引用产品:CL-0292
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Knockdown of kinesin family member 2C restricts cell proliferation and induces cell cycle arrest in gastric cancer(2022/11/30)
作者:Shuai Li, Yulian Ma, Chen Wu, Xinfang Hou, Shuai Li, Yulian Ma, Chen Wu, Xinfang Hou
期刊:HISTOLOGY AND HISTOPATHOLOGY
影响因子 :2.000