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产品概述
| 名称 | AsPC-1 (人转移胰腺腺癌细胞) (STR鉴定正确) |
| 别称 | AsPc-1; Aspc-1; ASPC-1; As-PC1; ASPC1; AsPC1; Aspc1; AsPc1 |
| 背景描述 | AsPC-1细胞来源于人胰腺癌病人腹水中的细胞裸鼠异种移植而产生的癌性腹水细胞；AsPC-1细胞可以表达CEA、人胰腺相关抗原、人胰腺特异性抗原和黏蛋白。 |
| 种属 | 人 |
| 年龄（性别） | 62岁 |
| 组织来源 | 胰腺；转移灶；腹水腺癌 |
| 生长特性 | 贴壁细胞 |
| 细胞形态 | 上皮细胞样 |
| 细胞类型 | 肿瘤细胞 |
| 肿瘤类型 | 胰腺癌细胞 |
| 生物安全等级 | 1 |
| 生长培养基 | RPMI-1640＋10% FBS＋1% P/S |
| 推荐传代比例 | 1:3-1:4 |
| 推荐换液频率 | 2~3次/周 |
| 倍增时间 | ~38-48 hours |
| 冻存条件 | 冻存液：55% 基础培养基+40%FBS+5%DMSO 温度：液氮 |
| 培养条件 | 气相：空气，95%；CO2，5% 温度：37℃ |
| 基因表达情况 | carcinoembryonic antigen (CEA); human pancreas associated antigen; human pancreas specific antigen; mucin |
| 保藏机构 | ATCC; CRL-1682 BCRC; 60494 ECACC; 96020930 |
STR鉴定
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STR位点信息
Amelogenin X CSF1PO 10,13 D2S1338 22,23 D3S1358 16 D5S818 12 D7S820 12,13 D8S1179 13,15 D13S317 9,12 D16S539 11 D18S51 18 D19S433 14 D21S11 28,30 FGA 24 PentaD 9,12 PentaE 5,12 TH01 7,9.3 TPOX 8,10 vWA 17 D6S1043 11,20 D12S391 19 D2S441 11,14 -
STR鉴定图
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参考文献
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ZMAT1 acts as a tumor suppressor in pancreatic ductal adenocarcinoma by inducing SIRT3/p53 signaling pathway(2022/04/07)
作者：Ma Zuyi, Li Zhenchong, Wang Shujie
期刊：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
DOI：10.1186/s13046-022-02310-8
影响因子 ：12.6580
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Albumin binding revitalizes NQO1 bioactivatable drugs as novel therapeutics for pancreatic cancer(2022/08/04)
作者：Lei Dou, Huiqin Liu, Kaixin Wang
期刊：JOURNAL OF CONTROLLED RELEASE
DOI：10.1016/j.jconrel.2022.07.033
影响因子 ：11.4670
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Upstream stimulatory factor 2 inhibits erastin-induced ferroptosis in pancreatic cancer through transcriptional regulation of pyruvate kinase M2(2022/09/20)
作者：Meijie Chen, Xuena Li, Bulin Du
期刊：BIOCHEMICAL PHARMACOLOGY
影响因子 ：6.1000
引用产品：CL-0027 CL-0042 CL-0059 CL-0184 CL-0448A CL-0627 CM-0059 CM-0448A
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MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation(2020/1/21)
作者：Wenjie Huang, Jianyou Gu, Tian Tao
期刊：Frontiers in Oncology
影响因子 ：5.738
引用产品：CL-0027
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MiR-24-3p Inhibits the Progression of Pancreatic Ductal Adenocarcinoma Through LAMB3 Downregulation(2020/01/21)
作者：Wenjie Huang, Jianyou Gu, Tian Tao
期刊：Frontiers in Oncology
影响因子 ：5.738
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Long non-coding RNA OIP5-AS1 promotes pancreatic cancer cell growth through sponging miR-342-3p via AKT/ERK signaling pathway(2020/3/10)
作者：Xiangpeng Meng, Jia Ma, Baosheng Wang
期刊：Journal Of Physiology And Biochemistry
DOI：10.1007/s13105-020-00734-4
影响因子 ：5.0800
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CMTM3 Overexpression Predicts Poor Survival and Promotes Proliferation and Migration in Pancreatic Cancer(2021/08/03)
作者：Zixuan Zhou, Zuyi Ma, Zhenchong Li
期刊：Journal of Cancer
影响因子 ：4.478
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Targeting the EZH2-PPAR Axis Is a Potential Therapeutic Pathway for Pancreatic Cancer(2021/7/22)
作者：Jilong Hu, Zhinan Zheng, Jia Lei
期刊：PPAR Research
影响因子 ：4.3850
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miR-23a-5p inhibits cell proliferation and invasion in pancreatic ductal adenocarcinoma by suppressing ECM1 expression(2019/5/15)
作者：Wenjie Huang, Yaohuan Huang, Jianyou Gu
期刊：American Journal of Translational Research
DOI：PMID:31217868
影响因子 ：4.0600
引用产品：CL-0027
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Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells(2020/5/20)
作者：Lei Zhang, Zhenyong Wang, Deshuai Kong
期刊：Bioscience Biotechnology And Biochemistry
DOI：10.1080/09168451.2020.1762479
影响因子 ：2.3370
