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产品概述
名称 | A549 [A-549] (人非小细胞肺癌细胞) (STR鉴定正确) |
别称 | A 549; A549; NCI-A549; A549/ATCC; A549 ATCC; A549ATCC; hA549 |
种属 | 人 |
生长特性 | 贴壁细胞 |
细胞形态 | 上皮细胞样 |
生长培养基 | Ham's F-12K+10% FBS+1% P/S |
冻存条件 | 冻存液:55% 基础培养基+40%FBS+5%DMSO 温度:液氮 |
培养条件 | 气相:空气,95%;CO2,5% 温度:37℃ |
推荐传代比例 | 1:3-1:4 |
推荐换液频率 | 2~3次/周 |
背景描述 | A549细胞是由D·J·Griad通过肺癌组织移植培养建系,源自于一位58岁白人男性;A549能通过胞苷二磷酸胆碱途径合成含有高含量不饱和脂肪酸的卵磷脂。 |
年龄(性别) | 男;58岁 |
组织来源 | 肺癌 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 肺癌细胞 |
生物安全等级 | 1 |
倍增时间 | ~22 hours |
保藏机构 | ATCC; CCL-185 ATCC; CRM-CCL-185 ATCC; CRL-7909BCRC; 60074 BCRJ; 0033 DSMZ; ACC-107 ECACC; 86012804 |
STR鉴定
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STR位点信息
Amelogenin X,Y CSF1PO 10,12 D2S1338 24 D3S1358 16 D5S818 11 D7S820 8,11 D8S1179 13,14 D13S317 11 D16S539 11,12 D18S51 14,17 D19S433 13 D21S11 29 FGA 23 PentaD 9 PentaE 7,11 TH01 8,9.3 TPOX 8,11 vWA 14 D6S1043 11,13 D12S391 18 D2S441 10,13 -
STR鉴定图
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参考文献
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Intrinsic bioactivity of black phosphorus nanomaterials on mitotic centrosome destabilization through suppression of PLK1 kinase(2021/08/05)
作者:Ximing Shao, Zhihao Ding, Wenhua Zhou
期刊:Nature Nanotechnology
DOI:10.1038/s41565-021-00952-x
影响因子 :38.300
引用产品:CL-0016 CL-0101 CL-0103 CL-0150A CL-0150B CL-0236 CL-0238
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LINC00173.v1 Promotes Angiogenesis and Progression of Lung Squamous Cell Carcinoma by Sponging miR-511-5p to Regulate VEGFA Expression(2020/07/10)
作者:Aibin Liu
期刊:Molecular Cancer
DOI:10.1186/s12943-020-01217-2
影响因子 :37.300
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Simulation guided intramolecular orthogonal reporters for dissecting cellular oxidative stress and response(2022/08/05)
作者:Yecan Pan, Rui Weng, Linghao Zhang
期刊:Nano Today
DOI:10.1016/j.nantod.2022.101573
影响因子 :17.400
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Lung cancer shapes commensal bacteria via exosome-like nanoparticles(2022/03/17)
作者:Jipeng Jianga, Jie Mei, Shasha Jiang
期刊:Nano Today
DOI:10.1016/j.nantod.2022.101451
影响因子 :17.400
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ANGPTL8 negatively regulates NF-κB activation byfacilitating selective autophagic degradation ofIKKγ(2017/12/18)
作者:Yu Zhang, Xian Guo, Wanyao Yan
期刊:Nature Communications
DOI:10.1038/s41467-017-02355-w
影响因子 :16.600
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Specific anti-glioma targeted-delivery strategy of engineered small extracellular vesicles dual-functionalised by Angiopep-2 and TAT peptides(2022/08/06)
作者:Zhanchi Zhu, Yuanxin Zhai, Ying Hao
期刊:Journal of Extracellular Vesicles
影响因子 :16.000
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Rotary Structural Color Spindles from Droplet Confined Magnetic Self-Assembly(2023/01/17)
作者:Hanxu Chen, Shuangshuang Miao, Yuanjin Zhao
期刊:Advanced Science
影响因子 :15.100
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Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury(2023/04/18)
作者:Lei Gao, Yongping Sun, Xinye Zhang
期刊:Advanced Science
影响因子 :15.100
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20(S)-Protopanaxatriol promotes the binding of P53 and DNA to regulate the antitumor network via multiomic analysis(2020/02/05)
作者:Zhihua Wang, Wenbo Wu, Xiangchen Guan
期刊:Acta Pharmaceutica Sinica B
DOI:10.1016/j.apsb.2020.01.017
影响因子 :14.500
引用产品:CL-0016
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Synthetic neutrophil extracellular traps dissect bactericidal contribution of NETs under regulation of α-1-antitrypsin(2023/04/28)
作者:Ting Yang, Jinlong Yu, Tasdiq Ahmed
期刊:Science Advances
影响因子 :13.600
引用产品:CL-0016
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Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription(2022/02/18)
作者:Weiwei Yang , Jing Li, Minghui Zhang
期刊:Journal Of Experimental & Clinical Cancer Research
DOI:10.1186/s13046-022-02260-1
影响因子 :11.300
引用产品:CL-0016 CL-0041 CL-0097 CL-0101 CL-0114 CL-0184 CL-0215 CL-0525
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Structural characterisation and antitumor activity against non-small cell lung cancer of polysaccharides from Sanghuangporus vaninii(2021/10/21)
作者:Xilin Wan, Xin Jin, Xinmin Wu
期刊:Carbohydrate Polymers
DOI:10.1016/j.carbpol.2021.118798
影响因子 :10.723
引用产品:CL-0016
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Combination of polythyleneimine regulating autophagy prodrug and Mdr1 siRNA for tumor multidrug resistance(2022/11/11)
作者:Wang Changduo, Li Zhipeng, Xu Ping, Xu Lisa, Han Shangcong, Sun Yong
期刊:JOURNAL OF NANOBIOTECHNOLOGY
DOI:10.1186/s12951-022-01689-y
影响因子 :10.200
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Intelligent Dual-Lock Deoxyribonucleic Acid Automatons Boosting Precise Tumor Imaging(2023/01/10)
作者:Liu Wang, Kang Wang, Xiaohui Wang
期刊:ACS Applied Materials & Interfaces
影响因子 :9.500
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Targeting visualization of malignant tumor based on the alteration of DWI signal generated by hTERT promoter–driven AQP1 overexpression(2022/01/19)
作者:Liang Zhang, Mingfu Gong, Sheng Lei
期刊:European Journal Of Nuclear Medicine And Molecular Imaging
DOI:10.1007/s00259-022-05684-1
影响因子 :9.100
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Noninvasive imaging of FAP expression using positron emission tomography: A comparative evaluation of a [18F]-labeled glycopeptide-containing FAPI with [18F]FAPI-42(2023/06/02)
作者:Jiawen Huang, LiLan Fu, XiaoJun Zhang
期刊:EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
DOI:10.1007/s00259-023-06282-5
影响因子 :9.100
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Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma(2022/08/30)
作者:Xiuqin Jia, Ming Xin, Juanjuan Xu
期刊:Cell Death & Disease
DOI:10.1038/s41419-022-05201-0
影响因子 :9.000
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A nanoplatform self-assembled by coordination delivers siRNA for lung cancer therapy(2023/02/16)
作者:Ziyao Wang, Jie Mei, Dongqi Ni
期刊:RARE METALS
DOI:10.1007/s12598-022-02185-w
影响因子 :8.800
引用产品:CL-0016
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Metal-Phenolic network pH-Sensitive Nanoparticle-Enabled Chemo/Chemodynamic therapy for lung cancer(2023/06/08)
作者:Daiwang Shi, Siyi Li, Wenhan Liu
期刊:MATERIALS & DESIGN
DOI:10.1016/j.matdes.2023.112072
影响因子 :8.400
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The O-glycosylating enzyme GALNT2 acts as an oncogenic driver in non-small cell lung cancer(2022/09/04)
作者:Qing Hu, Tian Tian, Yahui Leng
期刊:CELLULAR & MOLECULAR BIOLOGY LETTERS
DOI:10.1186/s11658-022-00378-w
影响因子 :8.300
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Drug-binding albumins forming stabilized nanoparticles for co-delivery of paclitaxel and resveratrol: In vitro/in vivo evaluation and binding properties investigation(2020/03/10)
作者:Yanna Zhao, Chang Cai, Min Liu
期刊:International Journal Of Biological Macromolecules
DOI:10.1016/j.ijbiomac.2020.03.060
影响因子 :8.200
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TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer(2021/04/30)
作者:Yuanming He, Xiumin Zhou, Shuoyi Jiang
期刊:Acta Pharmacologica Sinica
DOI:10.1038/s41401-021-00662-z
影响因子 :8.200
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Fluorinated carboxymethyl chitosan-based nano-prodrugs for precisely synergistic chemotherapy(2022/12/20)
作者:Chensong Zhang, Yining Song, Guoqing Yan
期刊:INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
DOI:10.1016/j.ijbiomac.2022.12.157
影响因子 :8.200
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Thioredoxin reductase 1 inhibitor shikonin promotes cell necroptosis via SecTRAPs generation and oxygen-coupled redox cycling(2021/12/30)
作者:Yue Zhang, Shibo Sun, Weiping Xu
期刊:Free Radical Biology And Medicine
DOI:10.1016/j.freeradbiomed.2021.12.314
影响因子 :8.101
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Curcumin suppresses the malignancy of non-small cell lung cancer by modulating the circ-PRKCA/miR-384/ITGB1 pathway(2021/03/06)
作者:Xiaoqing Xu, Xinyue Zhang, Yang Zhang
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2021.111439
影响因子 :7.500
引用产品:164210 164210-50 CL-0005 CL-0016 CL-0165 CL-0166 CL-0249 CL-0299 PB180120 PM150110
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Oxygen-supplied electrotherapy for enhanced photodynamic synergistic therapy overcomes hypoxia tumor microenvironment(2022/10/12)
作者:Chaozhou Li, Hui Tan, Ruitao Lu
期刊:Nanophotonics
影响因子 :7.500
引用产品:CL-0016
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Plumbagin reduction by thioredoxin reductase 1 possesses synergy effects with GLUT1 inhibitor on KEAP1-mutant NSCLC cells(2021/12/23)
作者:Shibo Sun, Yue Zhang, Weiping Xu
期刊:Biomedicine & Pharmacotherapy
DOI:10.1016/j.biopha.2021.112546
影响因子 :7.419
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Versatile Gold-Coupled Te-Carbon Dots for Quantitative Monitoring and Efficient Scavenging of Superoxide Anions(2021/07/06)
作者:Chang Xu, Wei Zhang, Ruixia Wang
期刊:Analytical Chemistry
DOI:10.1021/acs.analchem.1c00844
影响因子 :7.400
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De Novo Design of a Highly Selective Nonpeptide Fluorogenic Probe for Chymotrypsin Activity Sensing in a Living System(2022/12/14)
作者:Shiyu Liu, Xiaoting Zou, Xing Gao
期刊:Analytical Chemistry
DOI:10.1021/acs.analchem.2c03933
影响因子 :7.400
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The Immune Heterogeneity Between Pulmonary Adenocarcinoma and Squamous Cell Carcinoma: A Comprehensive Analysis Based on lncRNA Model(2021/07/29)
作者:Tao Yan, Guoyuan Ma, Kai Wang
期刊:Frontiers in Immunology
影响因子 :7.300
引用产品:CL-0016
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Prediction of prognosis, immunogenicity and efficacy of immunotherapy based on glutamine metabolism in lung adenocarcinoma(2022/08/11)
作者:Jichang Liu, Hongchang Shen, Wenchao Gu
期刊:Frontiers in Immunology
影响因子 :7.300
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Inhibition of DNA methylation derepresses PPARγ and attenuates pulmonary fibrosis(2021/08/11)
作者:Ai Wei, Qi Gao, Fang Chen
期刊:British Journal Of Pharmacology
影响因子 :7.300
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Erianin inhibits human lung cancer cell growth via PI3K/Akt/mTOR pathway in vitro and in vivo(2021/03/17)
作者:Huiqiong Zhang, Xiaofang Xie, Gangmin Li
期刊:Phytotherapy Research
DOI:10.1002/ptr.7154
影响因子 :7.200
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Tumor-suppressive E3 ubiquitin ligase CHIP inhibits the PBK/ERK axis to repress stem cell properties and radioresistance in non-small cell lung cancer(2022/11/27)
作者:Tan, Bo, Zhang, Jingwei, Wang, Wen, Ma, Haibo, Yang, Yuanyuan
期刊:APOPTOSIS
DOI:10.1007/s10495-022-01789-y
影响因子 :7.200
引用产品:CL-0016 CL-0165 CL-0298 CL-0496 CL-0668 CM-0496 PCK001 PM150110
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FERMT3 mediates cigarette smoke-induced epithelial–mesenchymal transition through Wnt/β-catenin signaling(2021/11/06)
作者:Xiaoshan Su, Junjie Chen, Xiaoping Lin
期刊:Respiratory Research
DOI:10.1186/s12931-021-01881-y
影响因子 :7.162
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pH-programmed responsive nanoplatform for synergistic cancer therapy based on single atom catalysts(2022/02/26)
作者:Mei Yao, Wenxiu Han, Lu Feng
期刊:European Journal Of Medicinal Chemistry
DOI:10.1016/j.ejmech.2022.114236
影响因子 :7.088
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RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma(2023/06/30)
作者:Yanan Guo, Rong Shen, Keren Yang
期刊:Cell Death Discovery
DOI:10.1038/s41420-023-01500-3
影响因子 :7.000
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Novel 4-anilinoquinazoline derivatives featuring an 1-adamantylmoiety as potent EGFR inhibitors with enhanced activity againstNSCLC cell lines(2016/01/26)
作者:Haiqing Yu, Yanxia Li, Yang Ge
期刊:European Journal of Medicinal Chemistry
DOI:DOI: 10.1016/j.ejmech.2016.01.045
影响因子 :6.700
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Design, synthesis, activity and molecular dynamics studies of 1,3,4-thiadiazole derivatives as selective allosteric inhibitors of SHP2 for the treatment of cancer(2023/06/24)
作者:Wenshan Liu, Jifeng Zhao, Xiaojing Guo
期刊:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
DOI:10.1016/j.ejmech.2023.115585
影响因子 :6.700
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Radiation-induced bystander effect on the genome of bone marrow mesenchymal stem cells in lung cancer(2022/10/14)
作者:Yiming Zhang, Liying Zhang, Yangyang Li
期刊:ANTIOXIDANTS & REDOX SIGNALING
影响因子 :6.600
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A mitochondria-targeting nitroreductase fluorescent probe with large Stokes shift and long-wavelength emission for imaging hypoxic status in tumor cells(2019/12/24)
作者:Quanzhi Yang, Shuzhan Wang, Duan Li
期刊:Analytica Chimica Acta
影响因子 :6.200
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Neural network-enhanced real-time impedance flow cytometry for single-cell intrinsic characterization(2022/1/18)
作者:Yongxiang Feng, Zhen Cheng, Huichao Chai
期刊:LAB ON A CHIP
影响因子 :6.100
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CAR-T-Cell Therapy for Solid Tumors Positive for Fibronectin Extra Domain B(2022/09/14)
作者:Zhijie Zhang, Chang Liu, Zhe Yang
期刊:Cells
影响因子 :6.000
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Inhibition of EZH2 Ameliorates Sepsis Acute Lung Injury (SALI) and Non-Small-Cell Lung Cancer (NSCLC) Proliferation through the PD-L1 Pathway(2022/12/07)
作者:Ziyi Wang, Zhe Guo, Xuesong Wang
期刊:Cells
影响因子 :6.000
引用产品:CL-0016
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AIEE-Active Flavones as a Promising Tool for the Real-Time Tracking of Uptake and Distribution in Live Zebrafish(2023/06/15)
作者:Yi Wu, Ying He, Huiqing Luo
期刊:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
影响因子 :5.600
引用产品:CL-0016
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miR-371b-5p-Engineered Exosomes Enhances Tumor Inhibitory Effect(2021/10/04)
作者:Qiang Xue, Yang Yang, Linlin Yang
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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Inhibition of miR-185-3p Confers Erlotinib Resistance Through Upregulation of PFKL/MET in Lung Cancers(2021/07/21)
作者:Ke Li, Xinling Zhu, Conghu Yuan
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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C1GALT1, Negatively Regulated by miR-181d-5p, Promotes Tumor Progression via Upregulating RAC1 in Lung Adenocarcinoma(2021/070/7)
作者:Xiaoxia Dong, Yongyu Liu, Xinzhou Deng
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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Prognostic Value of Genomic Instability of m 6 A-Related lncRNAs in Lung Adenocarcinoma(2022/03/03)
作者:Rui Li, JianPing Li, TingTing Liu
期刊:Frontiers in Cell and Developmental Biology
影响因子 :5.500
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Inhibition effect of oxyepiberberine isolated from Coptis chinensis franch. On non-small cell lung cancer based on a network pharmacology approach and experimental validation(2021/6/1)
作者:Ying Zhang, Yunfeng Yao, Yingjie Fu
期刊:Journal Of Ethnopharmacology
影响因子 :5.400
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Structurally Diverse Diterpenes from the South China Sea Soft Coral Sarcophyton trocheliophorum(2023/01/20)
作者:Yuting Song, Dandan Yu, Mingzhi Su
期刊:Marine Drugs
影响因子 :5.400
-
Nanomicelle-Microsphere Composite as a Drug Carrier to Improve Lung-Targeting Specificity for Lung Cancer(2022/02/25)
作者:Qianqian Zhang, Jianwei Bao, Tijie Duan
期刊:Pharmaceutics
DOI:10.3390/pharmaceutics14030510
影响因子 :5.400
-
Efficient Delivery of Gemcitabine by Estrogen Receptor-Targeted PEGylated Liposome and Its Anti-Lung Cancer Activity In Vivo and In Vitro(2023/03/19)
作者:Huan Tang, Zheng Zhang, Ming Zhu
期刊:Pharmaceutics
DOI:10.3390/pharmaceutics15030988
影响因子 :5.400
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Onvansertib inhibits the proliferation and improves the cisplatin-resistance of lung adenocarcinoma via β-catenin/c-Myc signaling pathway(2023/02/15)
作者:Rong Wang, Yihan Hou, Guojun Geng
期刊:American Journal of Cancer Research
DOI:PMID:36895968
影响因子 :5.300
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Structures and antitumor activities of ten new and twenty known surfactins from the deep-sea bacterium Limimaricola sp. SCSIO 53532( 2021/12/31)
作者:Wenping Ding, Yanqun Li, Min Chen
期刊: BIOORGANIC CHEMISTRY
DOI:10.1016/j.bioorg.2021.105589
影响因子 :5.100
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Aloe-emodin induces autophagy and apoptotic cell death in non-small cell lung cancer cells via Akt/mTOR and MAPK signaling(2020/9/11)
作者:Fengge Shen, Chunpo Ge, Peng Yuan
期刊:European Journal Of Pharmacology
DOI:10.1016/j.ejphar.2020.173550
影响因子 :5.000
引用产品:CL-0016
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Long non-coding RNA FAM83A antisense RNA 1 (lncRNA FAM83A-AS1) targets microRNA-141-3p to regulate lung adenocarcinoma cell proliferation, migration, invasion, and epithelial-mesenchymal transition progression(2022/02/14)
作者:Hongyu Huang, Chuyi Yang, Qichen Zhang
期刊:Bioengineered
DOI:10.1080/21655979.2022.2037871
影响因子 :4.900
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Ubiquilin 1 suppresses the cancer stem cell–like traits of non-small cell lung cancer cells by regulating reactive oxygen species homeostasis(2021/9/24)
作者:Ting Liu, Qianqian Ma, Wenjie Li
期刊:Bioengineered
DOI:10.1080/21655979.2021.1979353
影响因子 :4.900
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Regulating COX10-AS1 / miR-142-5p / PAICS axis inhibits the proliferation of non-small cell lung cancer(2021/7/29)
作者:Xinyu Tang, YiHe Wu, Jie Yang
期刊:Bioengineered
DOI:10.1080/21655979.2021.1957072
影响因子 :4.900
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Hsa_circ_0006677 regulates special AT-rich binding protein-2-mediated tumor-suppressive effect via functioning as a miR-1245a sponge in non-small cell lung cancer(2022/01/26)
作者:Xizhong Sui, Zongzhi Liu, Lei Niu
期刊:Bioengineered
DOI:10.1080/21655979.2022.2031400
影响因子 :4.900
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N6-methyladenosine-induced SVIL antisense RNA 1 restrains lung adenocarcinoma cell proliferation by destabilizing E2F1(2022/01/22)
作者:Zedong Hu, Liang Zhu, Yilin Zhang
期刊:Bioengineered
DOI:10.1080/21655979.2022.2025697
影响因子 :4.900
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24-Dehydrocholesterol Reductase alleviates oxidative damage-induced apoptosis in alveolar epithelial cells via regulating Phosphatidylinositol-3-Kinase/Protein Kinase B activation(2021/11/23)
作者:Ming Yao, Feng Li, Liang Xu
期刊:Bioengineered
DOI:10.1080/21655979.2021.2011634
影响因子 :4.900
引用产品:CL-0016
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Hsa_circ_0017639 regulates cisplatin resistance and tumor growth via acting as a miR-1296-5p molecular sponge and modulating sine oculis homeobox 1 expression in non-small cell lung cancer(2022/03/28)
作者:Feiyun Chang , Jiali Li , Quan Sun
期刊:Bioengineered
DOI:10.1080/21655979.2022.2053810
影响因子 :4.900
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Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275(2020/12/31)
作者:Junpeng Feng, Jianhang Li , Peng Qie
期刊:Bioengineered
DOI:10.1080/21655979.2020.1860492
影响因子 :4.900
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GRIN2D knockdown suppresses the progression of lung adenocarcinoma by regulating the E2F signalling pathway(2023/04/19)
作者:Zhitao Chen, Yanhui Song, Peipei Li
期刊:CELLULAR SIGNALLING
DOI:10.1016/j.cellsig.2023.110685
影响因子 :4.800
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Junctional adhesion molecule-like protein as a novel target for kaempferol to ameliorate lung adenocarcinoma(2023/04/06)
作者:Qian Wu, Yongbin Wang, Xiaowen Che
期刊:Journal of Integrative Medicine-JIM
DOI:10.1016/j.joim.2023.03.009
影响因子 :4.800
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Integrated analysis of single-cell and Bulk RNA sequencing reveals a malignancy-related signature in lung adenocarcinoma(2023/06/23)
作者:Mengxi Wu, Zhenyu Wu, Jun Yan
期刊:Frontiers in Oncology
影响因子 :4.700
-
18F-labeled FGFR1 peptide: a new PET probe for subtype FGFR1 receptor imaging(2023/04/27)
作者:Yang Chen, Jingya Han, Yan Zhao
期刊:Frontiers in Oncology
影响因子 :4.700
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Rutaecarpine Increases Anticancer Drug Sensitivity in Drug-Resistant Cells through MARCH8-Dependent ABCB1 Degradation(2021/09/02)
作者:Tingting Zou, Cheng Zeng, Junyan Qu
期刊:Biomedicines
DOI:10.3390/biomedicines9091143
影响因子 :4.700
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Triptonodiol, a Diterpenoid Extracted from Tripterygium wilfordii, Inhibits the Migration and Invasion of Non-Small-Cell Lung Cancer(2023/06/12)
作者:Xiaochen Ni, Xiaomin Jiang, Shilong Yu
期刊:MOLECULES
影响因子 :4.600
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Ajuforrestin A, an Abietane Diterpenoid from Ajuga ovalifolia var. calanthe, Induces A549 Cell Apoptosis by Targeting SHP2(2022/08/25)
作者:Hongling Yan, Miao Jiang, Fujin Yang
期刊:MOLECULES
影响因子 :4.600
引用产品:CL-0016
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Bioactive PKS–NRPS Alkaloids from the Plant-Derived Endophytic Fungus Xylaria arbuscula(2021/12/27)
作者:Ya Wang, Sinan Zhao, Tao Guo
期刊:Molecules
影响因子 :4.600
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Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3(2022/11/12)
作者:Wu Xu, Zhang Hui, Jiang Gang, Peng Minlian, Li Cheng, Lu Jiaxin, Jiang Shiyin, Yang Xiaoping, Jiang Yongliang
期刊:Clinical And Experimental Immunology
影响因子 :4.600
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Antioxidant Effects of Roasted Licorice in a Zebrafish Model and Its Mechanisms(2022/11/10)
作者:Qian Zhou, Shanshan Zhang, Xue Geng, Haiqiang Jiang, Yanpeng Dai, Ping Wang, Min Hua, Qi Gao, Shiyue Lang, Lijing Hou, Dianhua Shi, Meng Zhou
期刊:MOLECULES
影响因子 :4.600
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Circular RNA circ_0010235 sponges miR-338-3p to play oncogenic role in proliferation, migration and invasion of non-small-cell lung cancer cells through modulating KIF2A(2021/05/22)
作者:Yanan Zhu, Chunling Ma, Aiai Lv
期刊:Annals Of Medicine
DOI:10.1080/07853890.2021.1925736
影响因子 :4.400
-
Tanshinone IIA (TSIIA) represses the progression of non-small cell lung cancer by the circ_0020123/miR-1299/HMGB3 pathway(2022/12/31)
作者:Fei Sun, Xiaoli Yang, Wei Song
期刊:MOLECULAR AND CELLULAR BIOCHEMISTRY
DOI:10.1007/s11010-022-04646-3
影响因子 :4.300
引用产品:164210 164210-50 CL-0016 CL-0167 PB180120 PM150110 PM150910
-
E3 Ubiquitin Ligase CHIP Inhibits the Interaction between Hsp90β and MAST1 to Repress Radiation Resistance in Non-Small-Cell Lung Cancer Stem Cells(2022/09/20)
作者:Bo Tan, Jingwei Zhang, Wen Wang
期刊:Stem Cells International
影响因子 :4.300
-
Circ_0025039 acts an oncogenic role in the progression of non-small cell lung cancer through miR-636-dependent regulation of CORO1C(2022/01/16)
作者:Lei Wang, Cimei Zeng, Zhongren Chen
期刊:Molecular and Cellular Biochemistry
DOI:10.1007/s11010-021-04320-0
影响因子 :4.300
引用产品:164210 164210-50 CL-0016 CL-0122 CL-0165 CL-0249 PB180120 PM150110 PM150910
-
Ratiometric fluorescence and colorimetric dual-mode sensing platform based on carbon dots for detecting copper(II) ions and D-penicillamine(2022/01/06)
作者:Wei Zhang, Yu Zhang, Xin Liu
期刊:ANALYTICAL AND BIOANALYTICAL CHEMISTRY
DOI:10.1007/s00216-021-03789-4
影响因子 :4.300
引用产品:CL-0016
-
SPOCK2 and SPRED1 function downstream of EZH2 to impede the malignant progression of lung adenocarcinoma in vitro and in vivo(2023/01/11)
作者:Yang Liu, Xiaoxi Fan, Changrui Jiang
期刊:Human Cell
DOI:10.1007/s13577-023-00855-0
影响因子 :4.300
-
In Vivo Fluorescent Screening for HPPD-Targeted Herbicide Discovery(2022/08/07)
作者:Yixuan Fu, Ziye Zhang, Wuyingzheng Guo
期刊:PEST MANAGEMENT SCIENCE
DOI:10.1002/ps.7117
影响因子 :4.100
-
Optimized Fluorescent Probe for Specific Imaging of Glutathione S‐Transferases in Living Cells and Mice(2020/03/30)
作者:Tian Feng, Shouchang Gai, Haiqing Wei
期刊:Chemistry-An Asian Journal
影响因子 :4.100
引用产品:CL-0016
-
Elevated Notch1 enhances interleukin-22 production by CD4+ T cells via aryl hydrocarbon receptor in patients with lung adenocarcinoma(2018/12/21)
作者:Bo Pang, Cong Hu, Na Xing
期刊:Bioscience Reports
影响因子 :4.000
引用产品:CL-0016
-
Cell adhesion molecule 4 suppresses cell growth and metastasis by inhibiting the Akt signaling pathway in non-small cell lung cancer(2020/04/20)
作者:Fang Luo, Yi Zhao, Jiwei Liu
期刊:International Journal Of Biochemistry & Cell Biology
DOI:10.1016/j.biocel.2020.105750
影响因子 :4.000
-
LncRNA surfactant associated 1 activates large tumor suppressor kinase 1/Yes-associated protein pathway via modulating hypoxic exosome-delivered miR-4766–5p to inhibit lung adenocarcinoma metastasis(2022/10/22)
作者:Weiqiang Zhang, Miaochun Bai, Keqiang Liu
期刊:INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
DOI:10.1016/j.biocel.2022.106317
影响因子 :4.000
-
MicroRNA-21-3p modulates FGF2 to facilitate influenza A virus H5N1 replication by refraining type I interferon response(2020/5/29)
作者:Jianli Shi, Ping Feng, Tingting Gu
期刊:Bioscience Reports
影响因子 :4.000
引用产品:CL-0016
-
SLC7A5 is a lung adenocarcinoma-specific prognostic biomarker and participates in forming immunosuppressive tumor microenvironment(2022/10/02)
作者:Yong Liu, Guoyuan Ma, Jichang Liu
期刊:Heliyon
DOI:10.1016/j.heliyon.2022.e10866
影响因子 :4.000
-
High-content screening of active components of Traditional Chinese Medicine inhibiting TGF-β-induced cell EMT(2022/08/15)
作者:Mengzhen Xu, Qinghua Cui, Wen Su
期刊:Heliyon
DOI:10.1016/j.heliyon.2022.e10238
影响因子 :4.000
引用产品:CL-0016
-
Study on antitumor activity of three ruthenium arene complexes in vitro(2023/06/28)
作者:Xiaolong Peng, Qiang Tang, Huiyun Zhu
期刊:JOURNAL OF INORGANIC BIOCHEMISTRY
DOI:10.1016/j.jinorgbio.2023.112310
影响因子 :3.900
引用产品:CL-0016
-
Immunoassay-aptasensor for the determination of tumor-derived exosomes based on the combination of magnetic nanoparticles and hybridization chain reaction(2021/2/10)
作者:Hua Zhang, Yajuan Zhou, Dan Luo, Jingjian Liu
期刊:RSC Advances
影响因子 :3.900
引用产品:CL-0016
-
Mixed-ligand copper(II) hydrazone complexes: Synthesis, structure, and anti-lung cancer properties(2023/01/19)
作者:YouRu Wu, LiXia Hou, JianFeng Lan
期刊:JOURNAL OF MOLECULAR STRUCTURE
DOI:10.1016/j.molstruc.2023.134986
影响因子 :3.800
-
TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT(2021/11/7)
作者:Danjie Zhang, Liangzhang Sun, Jin Zhang
期刊:Toxicology And Applied Pharmacology
DOI:10.1016/j.taap.2021.115793
影响因子 :3.800
-
Molecular mechanism of Rhubarb in the treatment of non-small cell lung cancer based on network pharmacology and molecular docking technology(2022/08/06)
作者:Yeru Tan, Yu Lu
期刊:MOLECULAR DIVERSITY
DOI:10.1007/s11030-022-10501-w
影响因子 :3.800
引用产品:CL-0016
-
CLEC12B suppresses lung cancer progression by inducing SHP-1 expression and inactivating the PI3K/AKT signaling pathway(2021/11/12)
作者:Decai Chi, Dong Wang, Minghui Zhang
期刊:Experimental Cell Research
DOI:10.1016/j.yexcr.2021.112914
影响因子 :3.700
-
Proteasome 26S subunit, non-ATPase 1 (PSMD1) facilitated the progression of lung adenocarcinoma by the de-ubiquitination and stability of PTEN-induced kinase 1 (PINK1)(2022/02/19)
作者:Lihua Liu, Aihua Liu, Jun Dong
期刊:Experimental Cell Research
DOI:10.1016/j.yexcr.2022.113075
影响因子 :3.700
-
SLC6A8 is involved in the progression of non-small cell lung cancer through the Notch signaling pathway(2020/10/27)
作者:Yan Feng, Xiangyu Guo, Huaping Tang
期刊:Annals of Translational Medicine
影响因子 :3.616
-
Effect of circ_0000009 on lung adenocarcinoma progression by regulating PDZD2 in a ceRNA- and RBP- dependent manner(2023/06/10)
作者:Tan Tan, Mingming Ma, Shigui Xing
期刊:GENE
DOI:10.1016/j.gene.2023.147555
影响因子 :3.500
-
Circ-METTL15 contributes to the proliferation, metastasis, immune escape and restrains apoptosis in lung cancer by regulating miR-1299/PDL1 axis(2021/11/19)
作者:Rui Zhang, Liang Shang, Jinniang Nan
期刊:Autoimmunity
DOI:10.1080/08916934.2021.2001801
影响因子 :3.500
引用产品:164210 164210-50 CL-0016 CL-0165 CL-0166 CL-0229 PB180120 PM150110
-
Construction of a Humanized PBMC-PDX Model to Study the Efficacy of a Bacterial Marker in Lung Cancer Immunotherapy(2022/08/28)
作者:Chengwei Wu, Xinning Wang, Haitao Shang
期刊:DISEASE MARKERS
影响因子 :3.464
引用产品:CL-0016
-
Artesunate inhibits lung cancer cells via regulation of mitochondrial membrane potential and induction of apoptosis(2020/7/15)
作者:Yan Zhao, Jianghui Liu, Liang Liu
期刊:Molecular Medicine Reports
影响因子 :3.400
引用产品:CL-0016
-
Intelligent Genetic Decoding System Based on Nucleic Acid Isothermal Amplification for Non-Small Cell Lung Cancer Diagnosis(2023/03/12)
作者:Xiaonan Liu, Jiaxing Zhang, Kai Hua
期刊:Micromachines
影响因子 :3.400
-
Coculture with bone marrow‑derived mesenchymal stem cells attenuates inflammation and apoptosis in lipopolysaccharide‑stimulated alveolar epithelial cells via enhanced secretion of keratinocyte growth factor and angiopoietin‑1 modulating the Toll‑lik(2019/1/8)
作者:XuXin Chen, Lu Tang, Zhihai Han
期刊:Molecular Medicine Reports
影响因子 :3.400
引用产品:CL-0016
-
Nuclear factor-kappaB regulates the transcription of NADPH oxidase 1 in human alveolar epithelial cells(2021/03/23)
作者:Weijing Wu, Li Li, Xiaoshan Su
期刊:BMC Pulmonary Medicine
DOI:10.1186/s12890-021-01464-z
影响因子 :3.320
引用产品:CL-0016
-
BMI1 induces ubiquitination and protein degradation of Nod-like receptor family CARD domain containing 5 and suppresses human leukocyte antigen class I expression to induce immune escape in non-small cell lung cancer(2022/10/04)
作者:Zhihui Lu, Ganjie Tu, Silv Fu
期刊:KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
影响因子 :3.300
-
circRNA Hsa_circ_0020850 Silence Represses the Development of Lung Adenocarcinoma via Regulating miR-195-5p/IRS2 Axis(2020/10/28)
作者:Tuye Xin, Shuangshuang Li, Ying Zhang
期刊:Cancer Management and Research
影响因子 :3.300
引用产品:CL-0016
-
IL-17A Promotes the Migration, Invasion and the EMT Process of Lung Cancer Accompanied by NLRP3 Activation(2022/10/30)
作者:Wenping Liu, Miaomiao Xin, Qing Li
期刊:Biomed Research International
影响因子 :3.246
-
Ginsenoside CK Inhibits TGF-β-Induced Epithelial-Mesenchymal Transition in A549 Cell via SIRT1(2021/12/12)
作者:Mingyang Sun, Xuefeng Zhuang, Guangfu Lv
期刊:Biomed Research International
影响因子 :3.246
引用产品:CL-0016
-
AHNAK2 Is Associated with Poor Prognosis and Cell Migration in Lung Adenocarcinoma(2020/8/20)
作者:Shusen Zhang, Yuanyuan Lu, Lei Qi
期刊:Biomed Research International
影响因子 :3.246
引用产品:CL-0016
-
circRNA-mediated upregulation of HOXC9 is correlated with poor outcome and immune microenvironment infiltrates in LUAD(2022/10/14)
作者:Yunlong Liu, Liling Jing, Jie Zhang
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2022.10.043
影响因子 :3.100
-
TNNC1 Reduced Gemcitabine Sensitivity of Nonsmall-Cell Lung Cancer by Increasing Autophagy(2020/09/18)
作者:Xian Ye, Guanghui Xie, Zhijian Liu
期刊:Medical Science Monitor
影响因子 :3.100
引用产品:CL-0016
-
Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening(2023/02/07)
作者:Yicheng Ni, Zhongyuan Luo, Yixin Lv
期刊:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
DOI:10.1016/j.bbrc.2023.02.014
影响因子 :3.100
-
Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms(2020/12/22)
作者:Lulu Sun, Hongliang Dong, Weiqun Zhang
期刊:Dna And Cell Biology
影响因子 :3.100
引用产品:CL-0016
-
miR-324-3p reverses cisplatin resistance by inducing GPX4-mediated ferroptosis in lung adenocarcinoma cell line A549(2021/3/1)
作者:Shihua Deng, Dongming Wu, Li Li
期刊:Biochemical and Biophysical Research Communications
DOI:10.1016/j.bbrc.2021.02.077
影响因子 :3.100
引用产品:CL-0016
-
EGFR mutation status in Tunisian non-small-cell lung cancer patients evaluated by mutation-specific immunohistochemistry(2018/8/9)
作者:Zohra Mraihi1, Jihen Ben Amar , Hend Bouacha
期刊:BMC Pulmonary Medicine
影响因子 :3.100
引用产品:CL-0016
-
Circ_0086720 knockdown strengthens the radiosensitivity of non-small cell lung cancer via mediating the miR-375/SPIN1 axis(2020/09/16)
作者:Yurong Jin, Zhenjun Su, Hui Sheng
期刊:Neoplasma
DOI:10.4149/neo_2020_200331N333
影响因子 :3.000
-
Circ_0002476 regulates cell growth, invasion, and mtDNA damage in non–small cell lung cancer by targeting miR-1182/TFAM axis(2022/09/03)
作者:Weijie Wang, Haiting Sun, Xuan Ma
期刊:Thoracic Cancer
影响因子 :2.900
-
Overexpression of close homolog of L1 enhances the chemosensitivity of lung cancer cells via inhibition of the Akt pathway(2020/8/12)
作者:Xiangdao Cai, Bang Hu, Sheng Liu
期刊:Oncology Letters
影响因子 :2.900
-
Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma(2023/02/24)
作者:Rui Chen, Zhiping Wang, Tianzhu Lu
期刊:Thoracic Cancer
影响因子 :2.900
引用产品:CL-0016 CL-0161 CL-0165 CL-0166 CL-0298 CL-0668 CM-0161
-
MNX1 facilitates the malignant progress of lung adenocarcinoma through transcriptionally upregulating CCDC34(2023/06/13)
作者:Junhua Wu, Chongmei Yue, Weiguo Xu
期刊:Oncology Letters
影响因子 :2.900
-
Hsa_circ_0003220 Drives Chemoresistance of Human NSCLC Cells by Modulating miR-489-3p/IGF1(2023/06/16)
作者:Shaofeng Xia, Chenliang Wang
期刊:International Journal of Genomics
影响因子 :2.900
-
Anti-tumor cembrane diterpenoids from the South China Sea soft coral Lobophytum sp.(2023/02/28)
作者:Fan Yang, Yuting Song, Dandan Yu
期刊:CHEMISTRY & BIODIVERSITY
影响因子 :2.900
-
CircRNA PRH1-PRR4 stimulates RAB3D to regulate the malignant progression of NSCLC by sponging miR-877-5p(2022/01/25)
作者:Jun Ma, Quanxing Li, Yuling Li
期刊:Thoracic Cancer
影响因子 :2.900
-
One-step determination of deletion mutation based on loop-mediated isothermal amplification(2020/12/19)
作者:Xiaonan Liu, Chao Zhang, Sinong Zhang
期刊:Analytical Biochemistry
影响因子 :2.900
引用产品:CL-0016
-
Long noncoding RNA LINC00968 inhibits proliferation, migration and invasion of lung adenocarcinoma through targeting miR-22-5p/CDC14A axis(2021/09/14)
作者:Chao Wu, Xuzhao Bian, Liyuan Zhang
期刊:3 BIOTECH
DOI:10.1007/s13205-021-02981-8
影响因子 :2.893
-
Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p(2020/01/10)
作者:Runa Dao, Muli Wudu, Linping Hui
期刊:Pathology Research and Practice
影响因子 :2.800
-
LncRNA PCAT6 promotes proliferation, migration, invasion, and epithelial-mesenchymal transition of lung adenocarcinoma cell by targeting miR-545-3p(2023/02/14)
作者:Chuyi Yang, Hongyu Huang, Yongpeng Li
期刊:MOLECULAR BIOLOGY REPORTS
DOI:10.1007/s11033-023-08259-x
影响因子 :2.800
-
Pseudogene CSPG4P12 affects the biological behavior of non‑small cell lung cancer by Bcl‑2/Bax mitochondrial apoptosis pathway(2022/10/26)
作者:Wenqian Hu, Hongjiao Wu, Ang Li
期刊:Experimental and Therapeutic Medicine
影响因子 :2.700
-
Remifentanil modulates the TLR4‑mediated MMP‑9/TIMP1 balance and NF‑κB/STAT3 signaling in LPS‑induced A549 cells(2022/12/30)
作者:Jun Chang, Wei Zhang
期刊:Experimental and Therapeutic Medicine
影响因子 :2.700
引用产品:CL-0016
-
Qiyusanlong Formula Induces Autophagy in Non-Small-Cell Lung Cancer Cells and Xenografts through the mTOR Signaling Pathway(2021/03/22)
作者:Yating Gao, Xinheng Wang, Qinjun Yan
期刊:Evidence-Based Complementary and Alternative Medicine
影响因子 :2.650
引用产品:CL-0016
-
Potent anti-MRSA activity and synergism with aminoglycosides by flavonoid derivatives from the root barks of Morus alba, a traditional Chinese medicine(2019/07/13)
作者:Guoying Zuo, CuiXian Yang,ZhaoJua Ruan
期刊:Medicinal Chemistry Research
DOI:10.1007/s00044-019-02393-7
影响因子 :2.600
引用产品:CL-0016
-
The synergistic Reduning and cefmetazole sodium treatment of severe pneumonia is mediated by the AhR-Src-STAT3 pathway(2022/02/01)
作者:Shanjun Luo, Lianfang Gan, Shengxing Liu
期刊:Journal of Thoracic Disease
影响因子 :2.500
-
Dysregulated expression of microRNA involved in resistance to osimertinib in EGFR mutant non-small cell lung cancer cells(2023/04/24)
作者:Dianbao Zhang, Yukun Yang, Yixin Kang
期刊:Journal of Thoracic Disease
影响因子 :2.500
-
Circular RNA Circ_0005962 Contributes to Lung Adenocarcinoma Cell Proliferation and Stem Cell Formation Through Sponging of miR-3611 and Modulating CYP24A1 Expression(2022/12/21)
作者:Wenjing Lu, Zhigao Yu, Jun Liu
期刊:BIOCHEMICAL GENETICS
DOI:10.1007/s10528-022-10312-6
影响因子 :2.400
引用产品:164210-50 CL-0016 CL-0094 CL-0298 CL-0496 CM-0016 CM-0094 CM-0298 CM-0496 PB180120 PM150110 PM150210 PM150910
-
Atractylenolide III induces apoptosis by regulating the Bax/Bcl-2 signaling pathway in human colorectal cancer HCT-116 Cells in vitro and in vivo(2022/01/01)
作者:Dan Zhang, Xiaofang Li, Daqiang Song
期刊:Anti-Cancer Drugs
DOI:10.1097/CAD.0000000000001136
影响因子 :2.300
-
Ginsenoside Rg3 enhances the radiosensitivity of lung cancer A549 and H1299 cells via the PI3K/AKT signaling pathway(2023/02/15)
作者:Jialin Li, Bo Yang
期刊:IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
DOI:10.1007/s11626-023-00749-3
影响因子 :2.100
-
Involvement of ZDHHC9 in lung adenocarcinoma: regulation of PD-L1 stability via palmitoylation(2023/03/31)
作者:Zhe Li, Da Jiang, Fengling Liu
期刊:IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
DOI:10.1007/s11626-023-00755-5
影响因子 :2.100
-
MicroRNA-106a-5p alleviated the resistance of cisplatin in lung cancer cells by targeting Jumonji domain containing 6(2021/10/02)
作者:Xiang Ge, Yifei Jiang, Xun Hu
期刊:Transplant Immunology
DOI:10.1016/j.trim.2021.101478
影响因子 :2.032
-
Targeted delivery of quercetin by nanoparticles based on chitosan sensitizing paclitaxel-resistant lung cancer cells to paclitaxel(2020/08/25)
作者:Yonghong Wang, Hongli Yu, Saisai Wang
期刊:Materials Science and Engineering: C
DOI:10.1016/j.msec.2020.111442
影响因子 :1.900
-
Overexpression of Human Aspartyl (Asparaginyl) β-hydroxylase in NSCLC: Its Diagnostic Value by Means of Exosomes of Bronchoalveolar Lavage(2021/11/01)
作者:Haohao Zhu, Huai Liu, Jianfeng Wen
期刊:Applied Immunohistochemistry & Molecular Morphology
DOI:10.1097/PAI.0000000000000963
影响因子 :1.600
-
Hsa_circ_0079530/AQP4 Axis Is Related to Non-Small Cell Lung Cancer Development and Radiosensitivity.(2022/10/01)
作者:Xianghui Yang, Min Li, Yang Zhao
期刊:Annals of Thoracic and Cardiovascular Surgery
影响因子 :1.300
-
miR-137 represses migration and cell motility by targeting COX-2 in non-small cell lung cancer(2022/10/01)
作者:Yutu Luo, Suwei Hu, Fang Wang
期刊:Translational Cancer Research
影响因子 :0.900
-
Human EVI2B acts as a Janus-faced oncogene/antioncogene by differently affecting as per cancer type neoplastic cells growth and immune infiltration:(2023/03/23)
作者:Fangyingnan Zhang, Xinning Wang, Xiaoqi Zhang
期刊:Oncologie
DOI:10.1515/oncologie-2022-1002
影响因子 :0.900
-
MiR-582-3p participates in the regulation of biological behaviors of A549 cells by ambient PM 2.5 exposure(2021/09/30)
作者:Mei Yang, Liangliang Ju, Changlian Li
期刊:Environ Sci Pollut Res Int
DOI:10.1007/s11356-021-16801-2
影响因子 :0.000
引用产品:CL-0016